Richard W Birkinshaw

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 12

Top Venues

PLoS biology

Nature communications

Cell death and differentiation

Science signaling

Walter and Eliza Hall Institute of Medical Research

University of Bristol (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Walter and Eliza Hall Institute of Medical Research

Australia

Senior Research Officer :: Structural Biology

Monash University

Australia

Postdoc :: School of Biological Sciences

Education History

University of Bristol

United Kingdom

PHD :: School of Biochemistry

University of East Anglia

United Kingdom

BSC

Publications

Zheng Yuan, Mark F van Delft, Mark Xiang Li, Fransisca Sumardy, Brian J Smith, David C S Huang, Guillaume Lessene, Yelena Khakam, Ruitao Jin, Sitong He, Nicholas A Smith, Richard W Birkinshaw, Peter E Czabotar, Grant Dewson
Key residues in the VDAC2-BAK complex can be targeted to modulate apoptosis. PLoS biology 22 (5) (2024)
Zheng Yuan, Mark F van Delft, Mark Xiang Li, Fransisca Sumardy, Brian J Smith, David C S Huang, Guillaume Lessene, Yelena Khakam, Ruitao Jin, Sitong He, Nicholas A Smith, Richard W Birkinshaw, Peter E Czabotar, Grant Dewson
Key residues in the VDAC2-BAK complex can be targeted to modulate apoptosis. PLoS biology 22 (5) (2024)
Zheng Yuan, Mark F van Delft, Mark Xiang Li, Fransisca Sumardy, Brian J Smith, David C S Huang, Guillaume Lessene, Yelena Khakam, Ruitao Jin, Sitong He, Nicholas A Smith, Richard W Birkinshaw, Peter E Czabotar, Grant Dewson
Key residues in the VDAC2-BAK complex can be targeted to modulate apoptosis. PLoS biology 22 (5) (2024)
Zheng Yuan, Mark F van Delft, Mark Xiang Li, Fransisca Sumardy, Brian J Smith, David C S Huang, Guillaume Lessene, Yelena Khakam, Ruitao Jin, Sitong He, Nicholas A Smith, Richard W Birkinshaw, Peter E Czabotar, Grant Dewson
Key residues in the VDAC2-BAK complex can be targeted to modulate apoptosis. PLoS biology 22 (5) (2024)
Zheng Yuan, Grant Dewson, Peter E Czabotar, Richard W Birkinshaw
VDAC2 and the BCL-2 family of proteins. Biochemical Society transactions 49 (6) (2022)
Adeline Y Robin, Michelle S Miller, Sweta Iyer, Melissa X Shi, Ahmad Z Wardak, Daisy Lio, Nicholas A Smith, Brian J Smith, Richard W Birkinshaw, Peter E Czabotar, Ruth M Kluck, Peter M Colman
Structure of the BAK-activating antibody 7D10 bound to BAK reveals an unexpected role for the α1-α2 loop in BAK activation. Cell death and differentiation 29 (9) (2022)
Richard W Birkinshaw
Challenges in small-molecule target identification: a commentary on "BDA-366, a putative Bcl-2 BH4 domain antagonist, induces apoptosis independently of Bcl-2 in a variety of cancer cell models". Cell death and differentiation 28 (3) (2021)
Alan John, Michael A Järvå, Sayali Shah, Runyu Mao, Stephane Chappaz, Richard W Birkinshaw, Peter E Czabotar, Alvin W Lo, Nichollas E Scott, Ethan D Goddard-Borger
Yeast- and antibody-based tools for studying tryptophan C-mannosylation. Nature chemical biology 17 (4) (2021)
Kelan Chen, Richard W Birkinshaw, Alexandra D Gurzau, Iromi Wanigasuriya, Ruoyun Wang, Megan Iminitoff, Jarrod J Sandow, Samuel N Young, Patrick J Hennessy, Tracy A Willson, Denise A Heckmann, Andrew Ian Webb, Marnie E Blewitt, Peter E Czabotar, James G Murphy
Crystal structure of the hinge domain of Smchd1 reveals its dimerization mode and nucleic acid-binding residues. Science signaling 13 (636) (2020)
Katherine A Davies, Cheree Fitzgibbon, Samuel N Young, Sarah E Garnish, Wayland Yeung, Diane Coursier, Richard W Birkinshaw, Jarrod John Sandow, Wil I L Lehmann, Lung-Yu Liang, Isabelle S Lucet, James D Chalmers, Wayne M Patrick, Natarajan Kannan, Emma J Petrie, Peter E Czabotar, James G Murphy
Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues. Nature communications 11 (1) (2020)
Richard W Birkinshaw, Jia-Nan Gong, Cindy S Luo, Daisy Lio, Christine A White, Mary Ann Anderson, Piers Blombery, Guillaume L Lessene, Ian J Majewski, Rachel Thijssen, Andrew W Roberts, David C S Huang, Peter M Colman, Peter E Czabotar
Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations. Nature communications 10 (1) (2019)
Piers Blombery, Mary Ann Anderson, Jia-Nan Gong, Rachel Thijssen, Richard W Birkinshaw, Ella R Thompson, Charis E Teh, Tamia Nguyen, Zhen Xu, Christoffer Flensburg, Thomas E Lew, Ian J Majewski, Daniel H D Gray, David A Westerman, Constantine S Tam, John Francis Seymour, Peter E Czabotar, David Ching Siang Huang, Andrew W Roberts
Acquisition of the Recurrent Gly101Val Mutation in BCL2 Confers Resistance to Venetoclax in Patients with Progressive Chronic Lymphocytic Leukemia. Cancer discovery 9 (3) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Richard W Birkinshaw