Katherine A Davies

Publication Activity (10 Years)

Years Active: 2020-2023
Publications (10 Years): 6

Top Topics

Vascular Endothelial Growth Factor

Tyrosine Kinase

Top Venues

Nature communications

The Biochemical journal

Cell death and differentiation

This page only lists publications with an associated author ORCID identifier.

Publications

Yanxiang Meng, Sarah E Garnish, Katherine A Davies, Katrina A Black, Andrew P Leis, Christopher R Horne, Joanne M Hildebrand, Hanadi Hoblos, Cheree Fitzgibbon, Samuel N Young, Toby Dite, Laura F Dagley, Aarya Venkat, Natarajan Kannan, Akiko Koide, Shohei Koide, Alisa Glukhova, Peter E Czabotar, James G Murphy
Phosphorylation-dependent pseudokinase domain dimerization drives full-length MLKL oligomerization. Nature communications 14 (1) (2023)
Catia L Pierotti, Annette V Jacobsen, Christoph Grohmann, Ruby K Dempsey, Nima Etemadi, Joanne M Hildebrand, Cheree Fitzgibbon, Samuel N Young, Katherine A Davies, Wilhelmus J A Kersten, John Silke, Kym N Lowes, Hélène Jousset Sabroux, David C S Huang, Mark F van Delft, James G Murphy, Guillaume Lessene
The VEGFR/PDGFR tyrosine kinase inhibitor, ABT-869, blocks necroptosis by targeting RIPK1 kinase. The Biochemical journal 480 (9) (2023)
Ashish Sethi, Christopher R Horne, Cheree Fitzgibbon, Karyn L Wilde, Katherine A Davies, Sarah E Garnish, Annette V Jacobsen, André L Samson, Joanne M Hildebrand, Ahmad Z Wardak, Peter E Czabotar, Emma J Petrie, Paul R Gooley, James G Murphy
Membrane permeabilization is mediated by distinct epitopes in mouse and human orthologs of the necroptosis effector, MLKL. Cell death and differentiation 29 (9) (2022)
Yanxiang Meng, Katherine A Davies, Cheree Fitzgibbon, Samuel N Young, Sarah E Garnish, Christopher R Horne, Cindy Luo, Jean-Marc Garnier, Lung-Yu Liang, Angus D Cowan, André L Samson, Guillaume L Lessene, Jarrod John Sandow, Peter E Czabotar, James G Murphy
Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis. Nature communications 12 (1) (2021)
Katherine A Davies, Cheree Fitzgibbon, Samuel N Young, Sarah E Garnish, Wayland Yeung, Diane Coursier, Richard W Birkinshaw, Jarrod John Sandow, Wil I L Lehmann, Lung-Yu Liang, Isabelle S Lucet, James D Chalmers, Wayne M Patrick, Natarajan Kannan, Emma J Petrie, Peter E Czabotar, James G Murphy
Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues. Nature communications 11 (1) (2020)
André L Samson, Ying Zhang, Niall D Geoghegan, Xavier J Gavin, Katherine A Davies, Michael J Mlodzianoski, Lachlan W Whitehead, Daniel Frank, Sarah E Garnish, Cheree Fitzgibbon, Anne Hempel, Samuel N Young, Annette V Jacobsen, Wayne Cawthorne, Emma J Petrie, Maree C Faux, Kristy Shield-Artin, Najoua Lalaoui, Joanne M Hildebrand, John Silke, Kelly L Rogers, Guillaume L Lessene, Edwin D Hawkins, James G Murphy
MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis. Nature communications 11 (1) (2020)