Peter E Czabotar (Peter Czabotar)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 24

Top Topics

Endoplasmic Reticulum Stress

Duchenne Muscular Dystrophy

Top Venues

Cell death and differentiation

Nature communications

Nature chemical biology

Science signaling

This page only lists publications with an associated author ORCID identifier.

Publications

Hema Preethi Subas Satish, Sweta Iyer, Melissa X Shi, Agnes W Wong, Karla C Fischer, Ahmad Z Wardak, Daisy Lio, Jason M Brouwer, Rachel T Uren, Peter E Czabotar, Michelle S Miller, Ruth M Kluck
A novel inhibitory BAK antibody enables assessment of non-activated BAK in cancer cells. Cell death and differentiation (2024)
Hema Preethi Subas Satish, Sweta Iyer, Melissa X Shi, Agnes W Wong, Karla C Fischer, Ahmad Z Wardak, Daisy Lio, Jason M Brouwer, Rachel T Uren, Peter E Czabotar, Michelle S Miller, Ruth M Kluck
A novel inhibitory BAK antibody enables assessment of non-activated BAK in cancer cells. Cell death and differentiation 31 (6) (2024)
Hema Preethi Subas Satish, Sweta Iyer, Melissa X Shi, Agnes W Wong, Karla C Fischer, Ahmad Z Wardak, Daisy Lio, Jason M Brouwer, Rachel T Uren, Peter E Czabotar, Michelle S Miller, Ruth M Kluck
A novel inhibitory BAK antibody enables assessment of non-activated BAK in cancer cells. Cell death and differentiation 31 (6) (2024)
Hema Preethi Subas Satish, Sweta Iyer, Melissa X Shi, Agnes W Wong, Karla C Fischer, Ahmad Z Wardak, Daisy Lio, Jason M Brouwer, Rachel T Uren, Peter E Czabotar, Michelle S Miller, Ruth M Kluck
A novel inhibitory BAK antibody enables assessment of non-activated BAK in cancer cells. Cell death and differentiation 31 (6) (2024)
Hema Preethi Subas Satish, Sweta Iyer, Melissa X Shi, Agnes W Wong, Karla C Fischer, Ahmad Z Wardak, Daisy Lio, Jason M Brouwer, Rachel T Uren, Peter E Czabotar, Michelle S Miller, Ruth M Kluck
A novel inhibitory BAK antibody enables assessment of non-activated BAK in cancer cells. Cell death and differentiation 31 (6) (2024)
Peter E Czabotar, Ana J Garcia-Saez
Mechanisms of BCL-2 family proteins in mitochondrial apoptosis. Nature reviews. Molecular cell biology (2023)
Yanxiang Meng, Sarah E Garnish, Katherine A Davies, Katrina A Black, Andrew P Leis, Christopher R Horne, Joanne M Hildebrand, Hanadi Hoblos, Cheree Fitzgibbon, Samuel N Young, Toby Dite, Laura F Dagley, Aarya Venkat, Natarajan Kannan, Akiko Koide, Shohei Koide, Alisa Glukhova, Peter E Czabotar, James G Murphy
Phosphorylation-dependent pseudokinase domain dimerization drives full-length MLKL oligomerization. Nature communications 14 (1) (2023)
Michelle S Miller, Angus D Cowan, Jason M Brouwer, Sean T Smyth, Liuyu Peng, Ahmad Z Wardak, Rachel T Uren, Cindy Luo, Michael J Roy, Sayali Shah, Ziwen Tan, Gavin E Reid, Peter M Colman, Peter E Czabotar
Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids. The FEBS journal (2023)
Ruitao Jin, Sitong He, Katrina A Black, Oliver B Clarke, Di Wu, Jani Reddy Bolla, Paul Johnson, Agalya Periasamy, Ahmad Z Wardak, Peter E Czabotar, Peter M Colman, Carol V Robinson, Derek Laver, Brian J Smith, Jacqueline M Gulbis
Ion currents through Kir potassium channels are gated by anionic lipids. Nature communications 13 (1) (2022)
Yanxiang Meng, Christopher R Horne, André L Samson, Laura F Dagley, Samuel N Young, Jarrod John Sandow, Peter E Czabotar, James G Murphy
Human RIPK3 C-lobe phosphorylation is essential for necroptotic signaling. Cell death & disease 13 (6) (2022)
Ashish Sethi, Christopher R Horne, Cheree Fitzgibbon, Karyn L Wilde, Katherine A Davies, Sarah E Garnish, Annette V Jacobsen, André L Samson, Joanne M Hildebrand, Ahmad Z Wardak, Peter E Czabotar, Emma J Petrie, Paul R Gooley, James G Murphy
Membrane permeabilization is mediated by distinct epitopes in mouse and human orthologs of the necroptosis effector, MLKL. Cell death and differentiation 29 (9) (2022)
Adeline Y Robin, Michelle S Miller, Sweta Iyer, Melissa X Shi, Ahmad Z Wardak, Daisy Lio, Nicholas A Smith, Brian J Smith, Richard W Birkinshaw, Peter E Czabotar, Ruth M Kluck, Peter M Colman
Structure of the BAK-activating antibody 7D10 bound to BAK reveals an unexpected role for the α1-α2 loop in BAK activation. Cell death and differentiation 29 (9) (2022)
Alan John, Michael A Järvå, Sayali Shah, Runyu Mao, Stephane Chappaz, Richard W Birkinshaw, Peter E Czabotar, Alvin W Lo, Nichollas E Scott, Ethan D Goddard-Borger
Yeast- and antibody-based tools for studying tryptophan C-mannosylation. Nature chemical biology 17 (4) (2021)
Emma M Carrington, Cynthia Louis, Tobias Kratina, Manuela Hancock, Christine R Keenan, Nadia Iannarella, Rhys S Allan, Ahmad Z Wardak, Peter E Czabotar, Marco J Herold, Robyn L Schenk, Christine A White, Damian D'Silva, Yuyan Yang, Wesley Wong, Huon Wong, Vanessa L Bryant, Nicholas D Huntington, Jai Rautela, Robyn M Sutherland, Yifan Zhan, Jacinta A Hansen, Duong Nhu, Guillaume L Lessene, Ian P Wicks, Andrew M Lew
BCL-XL antagonism selectively reduces neutrophil life span within inflamed tissues without causing neutropenia. Blood advances 5 (11) (2021)
Sarah E Garnish, Yanxiang Meng, Akiko Koide, Jarrod John Sandow, Eric Denbaum, Annette V Jacobsen, Wayland Yeung, André L Samson, Christopher R Horne, Cheree Fitzgibbon, Samuel N Young, Phoebe P C Smith, Andrew Ian Webb, Emma J Petrie, Joanne M Hildebrand, Natarajan Kannan, Peter E Czabotar, Shohei Koide, James G Murphy
Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis. Nature communications 12 (1) (2021)
Yanxiang Meng, Katherine A Davies, Cheree Fitzgibbon, Samuel N Young, Sarah E Garnish, Christopher R Horne, Cindy Luo, Jean-Marc Garnier, Lung-Yu Liang, Angus D Cowan, André L Samson, Guillaume L Lessene, Jarrod John Sandow, Peter E Czabotar, James G Murphy
Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis. Nature communications 12 (1) (2021)
Yanxiang Meng, Jarrod John Sandow, Peter E Czabotar, James G Murphy
The regulation of necroptosis by post-translational modifications. Cell death and differentiation 28 (3) (2021)
Sarah T Diepstraten, Mary Ann Anderson, Peter E Czabotar, Guillaume L Lessene, Andreas Strasser, Gemma L Kelly
The manipulation of apoptosis for cancer therapy using BH3-mimetic drugs. Nature reviews. Cancer (2021)
Joanne M Hildebrand, Maria Kauppi, Ian J Majewski, Zikou Liu, Allison J Cox, Sanae Miyake, Emma J Petrie, Michael A Silk, Zhixiu Li, Maria C Tanzer, Gabriela Brumatti, Samuel N Young, Cathrine Hall, Sarah E Garnish, Jason Corbin, Michael D Stutz, Ladina Di Rago, Pradnya Gangatirkar, Emma C Josefsson, Kristin Rigbye, Holly Anderton, James A Rickard, Anne Tripaydonis, Julie M Sheridan, Thomas S Scerri, Victoria E Jackson, Peter E Czabotar, Jian-Guo Zhang, Leila Varghese, Cody C Allison, Marc Pellegrini, Gillian M Tannahill, Esme C Hatchell, Tracy A Willson, Dina Stockwell, Carolyn A de Graaf, Janelle Collinge, Adrienne Hilton, Natasha Silke, Sukhdeep K Spall, Diep Chau, Vicki Athanasopoulos, Donald Metcalf, Ronald M Laxer, Alexander G Bassuk, Benjamin W Darbro, Maria A Fiatarone Singh, Nicole Vlahovich, David Hughes, Maria Kozlovskaia, David Benjamin Ascher, Klaus Warnatz, Nils Venhoff, Jens Thiel, Christine Biben, Stefan Blum, John Reveille, Michael S Hildebrand, Carola G Vinuesa, Pamela A McCombe, Matthew A Brown, Benjamin T Kile, Catriona A Mclean, Melanie Bahlo, Seth L Masters, Hiroyasu Nakano, Polly J Ferguson, James G Murphy, Warren S Alexander, John Silke
A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction. Nature communications 11 (1) (2020)
Kelan Chen, Richard W Birkinshaw, Alexandra D Gurzau, Iromi Wanigasuriya, Ruoyun Wang, Megan Iminitoff, Jarrod J Sandow, Samuel N Young, Patrick J Hennessy, Tracy A Willson, Denise A Heckmann, Andrew Ian Webb, Marnie E Blewitt, Peter E Czabotar, James G Murphy
Crystal structure of the hinge domain of Smchd1 reveals its dimerization mode and nucleic acid-binding residues. Science signaling 13 (636) (2020)
Angus D Cowan, Nicholas A Smith, Jarrod John Sandow, Eugene A Kapp, Yepy Hardi Rustam, James G Murphy, Jason M Brouwer, Jonathan P Bernardini, Michael J Roy, Ahmad Z Wardak, Iris K Tan, Andrew Ian Webb, Jacqueline M Gulbis, Brian J Smith, Gavin E Reid, Grant Dewson, Peter M Colman, Peter E Czabotar
BAK core dimers bind lipids and can be bridged by them. Nature structural & molecular biology 27 (11) (2020)
Katherine A Davies, Cheree Fitzgibbon, Samuel N Young, Sarah E Garnish, Wayland Yeung, Diane Coursier, Richard W Birkinshaw, Jarrod John Sandow, Wil I L Lehmann, Lung-Yu Liang, Isabelle S Lucet, James D Chalmers, Wayne M Patrick, Natarajan Kannan, Emma J Petrie, Peter E Czabotar, James G Murphy
Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues. Nature communications 11 (1) (2020)
Richard W Birkinshaw, Jia-Nan Gong, Cindy S Luo, Daisy Lio, Christine A White, Mary Ann Anderson, Piers Blombery, Guillaume L Lessene, Ian J Majewski, Rachel Thijssen, Andrew W Roberts, David C S Huang, Peter M Colman, Peter E Czabotar
Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations. Nature communications 10 (1) (2019)
Mark F van Delft, Stephane Chappaz, Yelena Khakham, Chinh T Bui, Marlyse A Debrincat, Kym N Lowes, Jason M Brouwer, Christoph Grohmann, Phillip P Sharp, Laura F Dagley, Lucy Li, Kate McArthur, Meng-Xiao Luo, Hui San Chin, W Douglas Fairlie, Erinna F Lee, David Segal, Stéphane Duflocq, Romina Lessene, Sabrina Bernard, Laure Peilleron, Thao Nguyen, Caroline Miles, Soo San Wan, Rachael M Lane, Ahmad Wardak, Kurt Lackovic, Peter M Colman, Jarrod J Sandow, Andrew I Webb, Peter E Czabotar, Grant Dewson, Keith G Watson, David C S Huang, Guillaume L Lessene, Benjamin T Kile
A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis. Nature chemical biology 15 (11) (2019)