Rik Ossenkoppele

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 41

Top Topics

Cerebrospinal Fluid

Positron Emission Tomography

Cognitive Decline

Top Venues

Nature medicine

Nature communications

bioRxiv : the preprint server for biology

This page only lists publications with an associated author ORCID identifier.

Publications

Sophie E Mastenbroek, Jacob W Vogel, Lyduine E Collij, Geidy E Serrano, Cécilia Tremblay, Alexandra L Young, Richard A Arce, Holly A Shill, Erika D Driver-Dunckley, Shyamal H Mehta, Christine M Belden, Alireza Atri, Parichita Choudhury, Frederik Barkhof, Charles H Adler, Rik Ossenkoppele, Thomas G Beach, Oskar Hansson
Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology. Nature communications 15 (1) (2024)
Nicolas R Barthélemy, Gemma Salvadó, Suzanne E Schindler, Yingxin He, Shorena Janelidze, Lyduine E Collij, Benjamin Saef, Rachel L Henson, Charles D Chen, Brian A Gordon, Yan Li, Renaud La Joie, Tammie L S Benzinger, John C Morris, Niklas Mattsson-Carlgren, Sebastian Palmqvist, Rik Ossenkoppele, Gil D Rabinovici, Erik Stomrud, Randell J Bateman, Oskar Hansson
Highly accurate blood test for Alzheimer's disease is similar or superior to clinical cerebrospinal fluid tests. Nature medicine 30 (4) (2024)
Sophie E Mastenbroek, Arianna Sala, David Vállez García, Mahnaz Shekari, Gemma Salvadó, Luigi Lorenzini, Leonard Pieperhoff, Alle Meije Wink, Isadora Lopes Alves, Robin Wolz, Craig Ritchie, Merce Boada, Pieter Jelle Visser, Marco Bucci, Gill Farrar, Oskar Hansson, Agneta K Nordberg, Rik Ossenkoppele, Frederik Barkhof, Juan-Domingo Gispert, Elena Rodriguez-Vieitez, Lyduine E Collij, null null
Continuous β-Amyloid CSF/PET Imbalance Model to Capture Alzheimer Disease Heterogeneity. Neurology 103 (1) (2024)
Nicolas R Barthélemy, Gemma Salvadó, Suzanne E Schindler, Yingxin He, Shorena Janelidze, Lyduine E Collij, Benjamin Saef, Rachel L Henson, Charles D Chen, Brian A Gordon, Yan Li, Renaud La Joie, Tammie L S Benzinger, John C Morris, Niklas Mattsson-Carlgren, Sebastian Palmqvist, Rik Ossenkoppele, Gil D Rabinovici, Erik Stomrud, Randell J Bateman, Oskar Hansson
Highly Accurate Blood Test for Alzheimer's Disease Comparable or Superior to Clinical CSF Tests. Nature medicine (2024)
Nicolas R Barthélemy, Gemma Salvadó, Suzanne E Schindler, Yingxin He, Shorena Janelidze, Lyduine E Collij, Benjamin Saef, Rachel L Henson, Charles D Chen, Brian A Gordon, Yan Li, Renaud La Joie, Tammie L S Benzinger, John C Morris, Niklas Mattsson-Carlgren, Sebastian Palmqvist, Rik Ossenkoppele, Gil D Rabinovici, Erik Stomrud, Randell J Bateman, Oskar Hansson
Highly accurate blood test for Alzheimer's disease is similar or superior to clinical cerebrospinal fluid tests. Nature medicine 30 (4) (2024)
Nicolas R Barthélemy, Gemma Salvadó, Suzanne E Schindler, Yingxin He, Shorena Janelidze, Lyduine E Collij, Benjamin Saef, Rachel L Henson, Charles D Chen, Brian A Gordon, Yan Li, Renaud La Joie, Tammie L S Benzinger, John C Morris, Niklas Mattsson-Carlgren, Sebastian Palmqvist, Rik Ossenkoppele, Gil D Rabinovici, Erik Stomrud, Randell J Bateman, Oskar Hansson
Highly accurate blood test for Alzheimer's disease is similar or superior to clinical cerebrospinal fluid tests. Nature medicine (2024)
Lyduine E Collij, Sophie E Mastenbroek, Niklas Mattsson-Carlgren, Olof Strandberg, Ruben Smith, Shorena Janelidze, Sebastian Palmqvist, Rik Ossenkoppele, Oskar Hansson
Lewy body pathology exacerbates brain hypometabolism and cognitive decline in Alzheimer's disease. Nature communications 15 (1) (2024)
Nicolas R Barthélemy, Gemma Salvadó, Suzanne E Schindler, Yingxin He, Shorena Janelidze, Lyduine E Collij, Benjamin Saef, Rachel L Henson, Charles D Chen, Brian A Gordon, Yan Li, Renaud La Joie, Tammie L S Benzinger, John C Morris, Niklas Mattsson-Carlgren, Sebastian Palmqvist, Rik Ossenkoppele, Gil D Rabinovici, Erik Stomrud, Randell J Bateman, Oskar Hansson
Highly accurate blood test for Alzheimer's disease is similar or superior to clinical cerebrospinal fluid tests. Nature medicine (2024)
Nicolas R Barthélemy, Gemma Salvadó, Suzanne E Schindler, Yingxin He, Shorena Janelidze, Lyduine E Collij, Benjamin Saef, Rachel L Henson, Charles D Chen, Brian A Gordon, Yan Li, Renaud La Joie, Tammie L S Benzinger, John C Morris, Niklas Mattsson-Carlgren, Sebastian Palmqvist, Rik Ossenkoppele, Gil D Rabinovici, Erik Stomrud, Randell J Bateman, Oskar Hansson
Highly accurate blood test for Alzheimer's disease is similar or superior to clinical cerebrospinal fluid tests. Nature medicine 30 (4) (2024)
Sophie E Mastenbroek, Arianna Sala, David Vállez García, Mahnaz Shekari, Gemma Salvadó, Luigi Lorenzini, Leonard Pieperhoff, Alle Meije Wink, Isadora Lopes Alves, Robin Wolz, Craig Ritchie, Merce Boada, Pieter Jelle Visser, Marco Bucci, Gill Farrar, Oskar Hansson, Agneta K Nordberg, Rik Ossenkoppele, Frederik Barkhof, Juan-Domingo Gispert, Elena Rodriguez-Vieitez, Lyduine E Collij, null null
Continuous β-Amyloid CSF/PET Imbalance Model to Capture Alzheimer Disease Heterogeneity. Neurology 103 (1) (2024)
Nicolas R Barthélemy, Gemma Salvadó, Suzanne E Schindler, Yingxin He, Shorena Janelidze, Lyduine E Collij, Benjamin Saef, Rachel L Henson, Charles D Chen, Brian A Gordon, Yan Li, Renaud La Joie, Tammie L S Benzinger, John C Morris, Niklas Mattsson-Carlgren, Sebastian Palmqvist, Rik Ossenkoppele, Gil D Rabinovici, Erik Stomrud, Randell J Bateman, Oskar Hansson
Highly accurate blood test for Alzheimer's disease is similar or superior to clinical cerebrospinal fluid tests. Nature medicine 30 (4) (2024)
Nicolas R Barthélemy, Gemma Salvadó, Suzanne E Schindler, Yingxin He, Shorena Janelidze, Lyduine E Collij, Benjamin Saef, Rachel L Henson, Charles D Chen, Brian A Gordon, Yan Li, Renaud La Joie, Tammie L S Benzinger, John C Morris, Niklas Mattsson-Carlgren, Sebastian Palmqvist, Rik Ossenkoppele, Gil D Rabinovici, Erik Stomrud, Randell J Bateman, Oskar Hansson
Highly accurate blood test for Alzheimer's disease is similar or superior to clinical cerebrospinal fluid tests. Nature medicine 30 (4) (2024)
Nicolas R Barthélemy, Gemma Salvadó, Suzanne E Schindler, Yingxin He, Shorena Janelidze, Lyduine E Collij, Benjamin Saef, Rachel L Henson, Charles D Chen, Brian A Gordon, Yan Li, Renaud La Joie, Tammie L S Benzinger, John C Morris, Niklas Mattsson-Carlgren, Sebastian Palmqvist, Rik Ossenkoppele, Gil D Rabinovici, Erik Stomrud, Randell J Bateman, Oskar Hansson
Highly accurate blood test for Alzheimer's disease is similar or superior to clinical cerebrospinal fluid tests. Nature medicine 30 (4) (2024)
Sophie E Mastenbroek, Jacob W Vogel, Lyduine E Collij, Geidy E Serrano, Cécilia Tremblay, Alexandra L Young, Richard A Arce, Holly A Shill, Erika D Driver-Dunckley, Shyamal H Mehta, Christine M Belden, Alireza Atri, Parichita Choudhury, Frederik Barkhof, Charles H Adler, Rik Ossenkoppele, Thomas G Beach, Oskar Hansson
Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology. Nature communications 15 (1) (2024)
Sophie E Mastenbroek, Jacob W Vogel, Lyduine E Collij, Geidy E Serrano, Cécilia Tremblay, Alexandra L Young, Richard A Arce, Holly A Shill, Erika D Driver-Dunckley, Shyamal H Mehta, Christine M Belden, Alireza Atri, Parichita Choudhury, Frederik Barkhof, Charles H Adler, Rik Ossenkoppele, Thomas G Beach, Oskar Hansson
Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology. Nature communications 15 (1) (2024)
Sophie E Mastenbroek, Jacob W Vogel, Lyduine E Collij, Geidy E Serrano, Cécilia Tremblay, Alexandra L Young, Richard A Arce, Holly A Shill, Erika D Driver-Dunckley, Shyamal H Mehta, Christine M Belden, Alireza Atri, Parichita Choudhury, Frederik Barkhof, Charles H Adler, Rik Ossenkoppele, Thomas G Beach, Oskar Hansson
Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology. Nature communications 15 (1) (2024)
Sophie E Mastenbroek, Jacob W Vogel, Lyduine E Collij, Geidy E Serrano, Cécilia Tremblay, Alexandra L Young, Richard A Arce, Holly A Shill, Erika D Driver-Dunckley, Shyamal H Mehta, Christine M Belden, Alireza Atri, Parichita Choudhury, Frederik Barkhof, Charles H Adler, Rik Ossenkoppele, Thomas G Beach, Oskar Hansson
Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology. Nature communications 15 (1) (2024)
Sophie E Mastenbroek, Jacob W Vogel, Lyduine E Collij, Geidy E Serrano, Cecilia Tremblay, Alexandra L Young, Richard A Arce, Holly A Shill, Erika D Driver-Dunckley, Shyamal H Mehta, Christine M Belden, Alireza Atri, Parichita Choudhury, Frederik Barkhof, Charles H Adler, Rik Ossenkoppele, Thomas G Beach, Oskar Hansson
Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology. bioRxiv : the preprint server for biology (2023)
Sophie E Mastenbroek, Jacob W Vogel, Lyduine E Collij, Geidy E Serrano, Cecilia Tremblay, Alexandra L Young, Richard A Arce, Holly A Shill, Erika D Driver-Dunckley, Shyamal H Mehta, Christine M Belden, Alireza Atri, Parichita Choudhury, Frederik Barkhof, Charles H Adler, Rik Ossenkoppele, Thomas G Beach, Oskar Hansson
Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology. bioRxiv : the preprint server for biology (2023)
Sophie E Mastenbroek, Jacob W Vogel, Lyduine E Collij, Geidy E Serrano, Cecilia Tremblay, Alexandra L Young, Richard A Arce, Holly A Shill, Erika D Driver-Dunckley, Shyamal H Mehta, Christine M Belden, Alireza Atri, Parichita Choudhury, Frederik Barkhof, Charles H Adler, Rik Ossenkoppele, Thomas G Beach, Oskar Hansson
Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology. bioRxiv : the preprint server for biology (2023)
Kanta Horie, Gemma Salvadó, Nicolas R Barthélemy, Shorena Janelidze, Yan Li, Yingxin He, Benjamin Saef, Charles D Chen, Hong Jiang, Olof Strandberg, Alexa Pichet Binette, Sebastian Palmqvist, Chihiro Sato, Pallavi Sachdev, Akihiko Koyama, Brian A Gordon, Tammie L S Benzinger, David M Holtzman, John C Morris, Niklas Mattsson-Carlgren, Erik Stomrud, Rik Ossenkoppele, Suzanne E Schindler, Oskar Hansson, Randell J Bateman
CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer's disease. Nature medicine (2023)
Denise Visser, Sander C J Verfaillie, Iris Bosch, Iman Brouwer, Hayel Tuncel, Emma M Coomans, Roos M Rikken, Sophie E Mastenbroek, Sandeep S V Golla, Frederik Barkhof, Elsmarieke van de Giessen, Bart N M van Berckel, Wiesje M van der Flier, Rik Ossenkoppele
Tau pathology as determinant of changes in atrophy and cerebral blood flow: a multi-modal longitudinal imaging study. European journal of nuclear medicine and molecular imaging (2023)
Sophie E Mastenbroek, Jacob W Vogel, Lyduine E Collij, Geidy E Serrano, Cecilia Tremblay, Alexandra L Young, Richard A Arce, Holly A Shill, Erika D Driver-Dunckley, Shyamal H Mehta, Christine M Belden, Alireza Atri, Parichita Choudhury, Frederik Barkhof, Charles H Adler, Rik Ossenkoppele, Thomas G Beach, Oskar Hansson
Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology. bioRxiv : the preprint server for biology (2023)
Gemma Salvadó, Rik Ossenkoppele, Nicholas James Ashton, Thomas G Beach, Geidy E Serrano, Eric M Reiman, Henrik Zetterberg, Niklas Mattsson-Carlgren, Shorena Janelidze, Kaj Blennow, Oskar Hansson
Specific associations between plasma biomarkers and postmortem amyloid plaque and tau tangle loads. EMBO molecular medicine (2023)
Sophie E Mastenbroek, Jacob W Vogel, Lyduine E Collij, Geidy E Serrano, Cecilia Tremblay, Alexandra L Young, Richard A Arce, Holly A Shill, Erika D Driver-Dunckley, Shyamal H Mehta, Christine M Belden, Alireza Atri, Parichita Choudhury, Frederik Barkhof, Charles H Adler, Rik Ossenkoppele, Thomas G Beach, Oskar Hansson
Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology. bioRxiv : the preprint server for biology (2023)
Gemma Salvadó, Rik Ossenkoppele, Nicholas James Ashton, Thomas G Beach, Geidy E Serrano, Eric M Reiman, Henrik Zetterberg, Niklas Mattsson-Carlgren, Shorena Janelidze, Kaj Blennow, Oskar Hansson
Specific associations between plasma biomarkers and postmortem amyloid plaque and tau tangle loads. EMBO molecular medicine (2023)
Anna C van Loenhoud, Colin Groot, Diana I Bocancea, Frederik Barkhof, Charlotte E Teunissen, Philip Scheltens, Wiesje Maria van der Flier, Rik Ossenkoppele
Association of Education and Intracranial Volume With Cognitive Trajectories and Mortality Rates Across the Alzheimer Disease Continuum. Neurology 98 (16) (2022)
Willem S Eikelboom, Najoua Lazaar, Rozemarijn Lidewij van Bruchem-Visser, Francesco U S Mattace-Raso, Michiel Coesmans, Rik Ossenkoppele, Esther Van Den Berg, Janne M Papma
The recognition and management of neuropsychiatric symptoms in early Alzheimer's disease: a qualitative study among Dutch memory clinic physicians. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society 22 (5) (2022)
Lukas Frontzkowski, Michael Ewers, Matthias Brendel, Davina Biel, Rik Ossenkoppele, Paul Hager, Anna Steward, Anna Dewenter, Sebastian Niclas Roemer, Anna Rubinski, Katharina Buerger, Daniel Janowitz, Alexa Pichet Binette, Ruben Smith, Olof Strandberg, Niklas Mattsson Carlgren, Martin Dichgans, Oskar Hansson, Nicolai Franzmeier
Earlier Alzheimer's disease onset is associated with tau pathology in brain hub regions and facilitated tau spreading. Nature communications 13 (1) (2022)
Willem S Eikelboom, Amy den Teuling, Daphne E Pol, Michiel Coesmans, Sanne Franzen, Lize C Jiskoot, Judy van Hemmen, Ellen H Singleton, Rik Ossenkoppele, Frank Jan de Jong, Esther Van Den Berg, Janne M Papma
Biweekly fluctuations of neuropsychiatric symptoms according to the Neuropsychiatric Inventory: Erratic symptoms or scores? International journal of geriatric psychiatry 37 (7) (2022)
Alexa Pichet Binette, Nicolai Franzmeier, Nicola Spotorno, Michael Ewers, Matthias Brendel, Davina Biel, null null, Olof Strandberg, Shorena Janelidze, Sebastian Palmqvist, Niklas Mattsson-Carlgren, Ruben Smith, Erik Stomrud, Rik Ossenkoppele, Oskar Hansson
Amyloid-associated increases in soluble tau relate to tau aggregation rates and cognitive decline in early Alzheimer's disease. Nature communications 13 (1) (2022)
Rik Ossenkoppele, Alexa Pichet Binette, Colin Groot, Ruben Smith, Olof Strandberg, Sebastian Palmqvist, Erik Stomrud, Pontus Tideman, Tomas Ohlsson, Jonas Jögi, Keith Johnson, Reisa Sperling, Vincent Doré, Colin L Masters, Christopher Rowe, Denise Visser, Bart N M van Berckel, Wiesje Maria van der Flier, Suzanne Baker, William J Jagust, Heather J Wiste, Ronald C Petersen, Clifford R Jack, Oskar Hansson
Amyloid and tau PET-positive cognitively unimpaired individuals are at high risk for future cognitive decline. Nature medicine 28 (11) (2022)
Ellen H Singleton, Oskar Hansson, Yolande A L Pijnenburg, Renaud La Joie, William G Mantyh, Pontus Tideman, Erik Stomrud, Antoine Leuzy, Maurits Johansson, Olof Strandberg, Ruben Smith, Evi Berendrecht, Bruce L Miller, Leonardo Iaccarino, Lauren Edwards, Amelia Strom, Emma E Wolters, Emma Coomans, Denise Visser, Sandeep S V Golla, Hayel Tuncel, Femke Bouwman, John Cornelis van Swieten, Janne M Papma, Bart van Berckel, Philip Scheltens, Yolande A L Pijnenburg, Gil D Rabinovici, Rik Ossenkoppele
Heterogeneous distribution of tau pathology in the behavioural variant of Alzheimer's disease. Journal of neurology, neurosurgery, and psychiatry (2021)
Rik Ossenkoppele, Juhan Reimand, Ruben Smith, Antoine Leuzy, Olof Strandberg, Sebastian Palmqvist, Erik Stomrud, Henrik Zetterberg, null null, Philip Scheltens, Jeffrey L Dage, Femke Bouwman, Kaj Blennow, Niklas Mattsson-Carlgren, Shorena Janelidze, Oskar Hansson
Tau PET correlates with different Alzheimer's disease-related features compared to CSF and plasma p-tau biomarkers. EMBO molecular medicine 13 (8) (2021)
Willem S Eikelboom, Esther van den Berg, Ellen H Singleton, Sara J Baart, Michiel Coesmans, Annebet E Leeuwis, Charlotte E Teunissen, Bart N M van Berckel, Yolande A L Pijnenburg, Philip Scheltens, Wiesje Maria van der Flier, Rik Ossenkoppele, Janne M Papma
Neuropsychiatric and Cognitive Symptoms Across the Alzheimer Disease Clinical Spectrum: Cross-sectional and Longitudinal Associations. Neurology 97 (13) (2021)
Gemma Salvadó, Daniel Ferreira, Grégory Operto, Irene Cumplido-Mayoral, Eider M Arenaza-Urquijo, Raffaele Cacciaglia, Juan Domingo Gispert, Natàlia Vilor-Tejedor, Carolina Minguillón, Colin Groot, Wiesje Maria van der Flier, Frederik Barkhof, Philip Scheltens, Rik Ossenkoppele, Silke Kern, Anna Zettergren, Ingmar Skoog, Jakub Hort, Erik Stomrud, Danielle van Westen, Oskar Hansson, José Luis L Molinuevo, Lars-Olof Wahlund, Erik Westman, Juan-Domingo Gispert, null null
The protective gene dose effect of the APOE ε2 allele on gray matter volume in cognitively unimpaired individuals. Alzheimer's & dementia : the journal of the Alzheimer's Association (2021)
Emma E Wolters, Janne M Papma, Sander C J Verfaillie, Denise Visser, Emma Weltings, Colin Groot, Emma Louise van der Ende, Lucia A A Giannini, Hayel Tuncel, Tessa Timmers, Ronald Boellaard, Maqsood M Yaqub, Danielle M E van Assema, Dennis A Kuijper, Marcel Segbers, Annemieke J M Rozemuller, Frederik Barkhof, Albert D Windhorst, Wiesje Maria van der Flier, Yolande A L Pijnenburg, Philip Scheltens, Bart N M van Berckel, John Cornelis van Swieten, Rik Ossenkoppele, Harro Seelaar
[18F]Flortaucipir PET Across Various MAPT Mutations in Presymptomatic and Symptomatic Carriers. Neurology 97 (10) (2021)
Juhan Reimand, Baayla Dimitri Catharina Boon, Lyduine E Collij, Charlotte E Teunissen, Annemieke J M Rozemuller, Bart N M van Berckel, Philip Scheltens, Rik Ossenkoppele, Femke H Bouwman
Amyloid-β PET and CSF in an autopsy-confirmed cohort. Annals of clinical and translational neurology 7 (11) (2020)
Rik Ossenkoppele, Antoine Leuzy, Hanna Cho, Carole H Sudre, Olof Strandberg, Ruben Smith, Sebastian Palmqvist, Niklas Mattsson-Carlgren, Tomas Olsson, Jonas Jögi, Erik Stormrud, Young Hoon Ryu, Jae Yong Choi, null null, null null, Adam L Boxer, Maria L Gorno-Tempini, Bruce L Miller, David Soleimani-Meigooni, Leonardo Iaccarino, Renaud La Joie, Edilio Borroni, Gregory Klein, Michael J Pontecorvo, Michael D Devous, Sylvia Villeneuve, Chul Hyoung Lyoo, Gil D Rabinovici, Oskar Hansson
The impact of demographic, clinical, genetic, and imaging variables on tau PET status. European journal of nuclear medicine and molecular imaging 48 (7) (2020)
Juhan Reimand, Lyduine Collij, Philip Scheltens, Femke Bouwman, Rik Ossenkoppele, null null
Association of amyloid-β CSF/PET discordance and tau load 5 years later. Neurology 95 (19) (2020)
Jacob W Vogel, Niklas Mattsson, Yasser Iturria-Medina, Olof T Strandberg, Michael Schöll, Christian Dansereau, Sylvia Villeneuve, Wiesje M van der Flier, Philip Scheltens, Pierre Bellec, Alan C Evans, Oskar Hansson, Rik Ossenkoppele, null null, null null
Data-driven approaches for tau-PET imaging biomarkers in Alzheimer's disease. Human brain mapping 40 (2) (2018)