Robert L Kortum (Robert Kortum)

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 13

Top Venues

bioRxiv : the preprint server for biology

Science signaling

Cancers

Proceedings of the National Academy of Sciences of the United States of America

Uniformed Services University of the Health Sciences

University of Nebraska Medical Center (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Uniformed Services University of the Health Sciences

United States

Assistant Professor :: Pharmacololgy and Molecular Therapeutics

Education History

University of Nebraska Medical Center

United States

PHD :: Pathology and Microbiology, Eppley Cancer Center

University of Nebraska-Lincoln

United States

BSC

Publications

Stacey Stauffer, Jacob S Roth, Edjay R Hernandez, Joshua T Kowalczyk, Nancy E Sealover, Katie E Hebron, Amy James, Kristine A Isanogle, Lisa A Riffle, Lilia V Ileva, Xiaoling Luo, Jin-Qiu Chen, Noemi Kedei, Robert L Kortum, Haiyan Lei, Jack F Shern, Joseph D Kalen, Elijah F Edmondson, Matthew D Hall, Simone Difilippantonio, Carol J Thiele, Marielle E Yohe
Preclinical Therapeutic Efficacy of RAF/MEK/ERK and IGF1R/AKT/mTOR Inhibition in Neuroblastoma. Cancers 16 (13) (2024)
Stacey Stauffer, Jacob S Roth, Edjay R Hernandez, Joshua T Kowalczyk, Nancy E Sealover, Katie E Hebron, Amy James, Kristine A Isanogle, Lisa A Riffle, Lilia V Ileva, Xiaoling Luo, Jin-Qiu Chen, Noemi Kedei, Robert L Kortum, Haiyan Lei, Jack F Shern, Joseph D Kalen, Elijah F Edmondson, Matthew D Hall, Simone Difilippantonio, Carol J Thiele, Marielle E Yohe
Preclinical Therapeutic Efficacy of RAF/MEK/ERK and IGF1R/AKT/mTOR Inhibition in Neuroblastoma. Cancers 16 (13) (2024)
Brianna R Daley, Nancy E Sealover, Erin Sheffels, Jacob M Hughes, Daniel Gerlach, Marco H Hofmann, Kaja Kostyrko, Barbara Mair, Amanda Linke, Zaria Beckley, Andrew Frank, Cliffton L Dalgard, Robert L Kortum
SOS1 inhibition enhances the efficacy of and delays resistance to G12C inhibitors in lung adenocarcinoma. bioRxiv : the preprint server for biology (2023)
Patricia L Theard, Amanda J Linke, Nancy E Sealover, Brianna R Daley, Johnny Yang, Katherine Cox, Robert L Kortum
SOS2 modulates the threshold of EGFR signaling to regulate osimertinib efficacy and resistance in lung adenocarcinoma. Molecular oncology (2023)
Brianna R Daley, Nancy E Sealover, Erin Sheffels, Jacob M Hughes, Daniel Gerlach, Marco H Hofmann, Kaja Kostyrko, Barbara Mair, Amanda Linke, Zaria Beckley, Andrew Frank, Cliffton L Dalgard, Robert L Kortum
SOS1 inhibition enhances the efficacy of and delays resistance to G12C inhibitors in lung adenocarcinoma. bioRxiv : the preprint server for biology (2023)
Brianna R Daley, Nancy E Sealover, Erin Sheffels, Jacob Hughes, Daniel Gerlach, Marco H Hofmann, Kaja Kostyroko, Barbara Mair, Amanda Linke, Zaria Beckley, Andrew Frank, Cliffton L Dalgard, Robert L Kortum
SOS1 inhibition enhances the efficacy of and delays resistance to G12C inhibitors in lung adenocarcinoma. bioRxiv : the preprint server for biology (2023)
Brianna R Daley, Heidi M Vieira, Chaitra Rao, Jacob M Hughes, Zaria M Beckley, Dianna H Huisman, Deepan Chatterjee, Nancy E Sealover, Katherine Cox, James W Askew, Robert A Svoboda, Kurt W Fisher, Robert E Lewis, Robert L Kortum
SOS1 and KSR1 modulate MEK inhibitor responsiveness to target resistant cell populations based on PI3K and KRAS mutation status. Proceedings of the National Academy of Sciences of the United States of America 120 (47) (2023)
Nancy E Sealover, Robert L Kortum
Heterogeneity in RAS mutations: One size does not fit all. Science signaling 15 (746) (2022)
Katie E Hebron, Xiaolin Wan, Jacob S Roth, David J Liewehr, Nancy E Sealover, William J E Frye, Angela Kim, Stacey Stauffer, Olivia L Perkins, Wenyue Sun, Kristine A Isanogle, Christina M Robinson, Amy James, Parirokh Awasthi, Priya Shankarappa, Xiaoling Luo, Haiyan Lei, Donna Butcher, Roberta Smith, Elijah F Edmondson, Jin-Qiu Chen, Noemi Kedei, Cody J Peer, Jack F Shern, William Douglas Figg, Lu Chen, Matthew D Hall, Simone Difilippantonio, Frederic G Barr, Robert L Kortum, Robert W Robey, Angelina V Vaseva, Javed Khan, Marielle E Yohe
The combination of trametinib and ganitumab is effective in RAS-mutated PAX-fusion negative rhabdomyosarcoma models. Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Erin Sheffels, Robert L Kortum
Breaking Oncogene Addiction: Getting RTK/RAS-Mutated Cancers off the SOS. Journal of medicinal chemistry 64 (10) (2021)
Izzy Owen, Debra Yee, Hala Wyne, Theodora Myrto Perdikari, Victoria Johnson, Jeremy T Smyth, Robert L Kortum, Nicolas L Fawzi, Frank Shewmaker
The oncogenic transcription factor FUS-CHOP can undergo nuclear liquid-liquid phase separation. Journal of cell science 134 (17) (2021)
Patricia L Theard, Erin Sheffels, Nancy E Sealover, Amanda J Linke, David J Pratico, Robert L Kortum
Marked synergy by vertical inhibition of EGFR signaling in NSCLC spheroids shows SOS1 is a therapeutic target in EGFR-mutated cancer. eLife 9 (2020)
Erin Sheffels, Nancy E Sealover, Chenyue Wang, Do Hyung Kim, Isabella A Vazirani, Elizabeth Lee, Elizabeth M Terrell, Deborah K Morrison, Ji Luo, Robert L Kortum
Oncogenic RAS isoforms show a hierarchical requirement for the guanine nucleotide exchange factor SOS2 to mediate cell transformation. Science signaling 11 (546) (2018)

Robert L Kortum.css-eqlu8i{font-size:small;padding-left:4px;} (Robert Kortum)

Publication Activity (10 Years)

Top Topics

Top Venues

Robert L Kortum (Robert Kortum)