Matthew D Hall (Matthew Hall, Mathew D Hall)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 66

Top Venues

Journal of medicinal chemistry

Nature communications

ACS pharmacology & translational science

bioRxiv : the preprint server for biology

This page only lists publications with an associated author ORCID identifier.

Publications

Yi Zhang, Shuyan Zhou, Yan Kai, Ya-Qin Zhang, Changmin Peng, Zhuqing Li, Muhammad Jameel Mughal, Belmar Julie, Xiaoyan Zheng, Junfeng Ma, Cynthia X Ma, Min Shen, Matthew D Hall, Shunqiang Li, Wenge Zhu
O-GlcNAcylation of MITF regulates its activity and CDK4/6 inhibitor resistance in breast cancer. Nature communications 15 (1) (2024)
Yi Zhang, Shuyan Zhou, Yan Kai, Ya-Qin Zhang, Changmin Peng, Zhuqing Li, Muhammad Jameel Mughal, Belmar Julie, Xiaoyan Zheng, Junfeng Ma, Cynthia X Ma, Min Shen, Matthew D Hall, Shunqiang Li, Wenge Zhu
O-GlcNAcylation of MITF regulates its activity and CDK4/6 inhibitor resistance in breast cancer. Nature communications 15 (1) (2024)
Yi Zhang, Shuyan Zhou, Yan Kai, Ya-Qin Zhang, Changmin Peng, Zhuqing Li, Muhammad Jameel Mughal, Belmar Julie, Xiaoyan Zheng, Junfeng Ma, Cynthia X Ma, Min Shen, Matthew D Hall, Shunqiang Li, Wenge Zhu
O-GlcNAcylation of MITF regulates its activity and CDK4/6 inhibitor resistance in breast cancer. Nature communications 15 (1) (2024)
Xin Hu, Paul Shinn, Zina Itkin, Lin Ye, Ya-Qin Zhang, Min Shen, Stephanie Ford-Scheimer, Matthew D Hall
A Comprehensive Collection of Pain and Opioid Use Disorder Compounds for High-Throughput Screening and Artificial Intelligence-Driven Drug Discovery. ACS pharmacology & translational science 7 (8) (2024)
Xin Hu, Paul Shinn, Zina Itkin, Lin Ye, Ya-Qin Zhang, Min Shen, Stephanie Ford-Scheimer, Matthew D Hall
A Comprehensive Collection of Pain and Opioid Use Disorder Compounds for High-Throughput Screening and Artificial Intelligence-Driven Drug Discovery. ACS pharmacology & translational science 7 (8) (2024)
Stacey Stauffer, Jacob S Roth, Edjay R Hernandez, Joshua T Kowalczyk, Nancy E Sealover, Katie E Hebron, Amy James, Kristine A Isanogle, Lisa A Riffle, Lilia V Ileva, Xiaoling Luo, Jin-Qiu Chen, Noemi Kedei, Robert L Kortum, Haiyan Lei, Jack F Shern, Joseph D Kalen, Elijah F Edmondson, Matthew D Hall, Simone Difilippantonio, Carol J Thiele, Marielle E Yohe
Preclinical Therapeutic Efficacy of RAF/MEK/ERK and IGF1R/AKT/mTOR Inhibition in Neuroblastoma. Cancers 16 (13) (2024)
Yi Zhang, Shuyan Zhou, Yan Kai, Ya-Qin Zhang, Changmin Peng, Zhuqing Li, Muhammad Jameel Mughal, Belmar Julie, Xiaoyan Zheng, Junfeng Ma, Cynthia X Ma, Min Shen, Matthew D Hall, Shunqiang Li, Wenge Zhu
O-GlcNAcylation of MITF regulates its activity and CDK4/6 inhibitor resistance in breast cancer. Nature communications 15 (1) (2024)
Stacey Stauffer, Jacob S Roth, Edjay R Hernandez, Joshua T Kowalczyk, Nancy E Sealover, Katie E Hebron, Amy James, Kristine A Isanogle, Lisa A Riffle, Lilia V Ileva, Xiaoling Luo, Jin-Qiu Chen, Noemi Kedei, Robert L Kortum, Haiyan Lei, Jack F Shern, Joseph D Kalen, Elijah F Edmondson, Matthew D Hall, Simone Difilippantonio, Carol J Thiele, Marielle E Yohe
Preclinical Therapeutic Efficacy of RAF/MEK/ERK and IGF1R/AKT/mTOR Inhibition in Neuroblastoma. Cancers 16 (13) (2024)
Yi Zhang, Shuyan Zhou, Yan Kai, Ya-Qin Zhang, Changmin Peng, Zhuqing Li, Muhammad Jameel Mughal, Belmar Julie, Xiaoyan Zheng, Junfeng Ma, Cynthia X Ma, Min Shen, Matthew D Hall, Shunqiang Li, Wenge Zhu
O-GlcNAcylation of MITF regulates its activity and CDK4/6 inhibitor resistance in breast cancer. Nature communications 15 (1) (2024)
Wenge Zhu, Y I Zhang, Shuyan Zhou, Yan Kai, Ya-Qin Zhang, Changmin Peng, Zhuqing Li, Muhammad Mughal, Junfeng Ma, Shunqiang Li, Cynthia X Ma, Min Shen, Matthew D Hall
O-GlcNAcylation of MITF regulates its activity and CDK4/6 inhibitor resistance in breast cancer. Research square (2023)
Maryam Safari, Luigi Scotto, Thomas Litman, Lubov A Petrukhin, Hu Zhu, Min Shen, Robert W Robey, Matthew D Hall, Tito Fojo, Susan E Bates
Novel Therapeutic Strategies Exploiting the Unique Properties of Neuroendocrine Neoplasms. Cancers 15 (20) (2023)
Lei Shi, William Shen, Mindy I Davis, Ke Kong, Phuong Vu, Supriya K Saha, Ramzi Adil, Johannes Kreuzer, Regina Egan, Tobie D Lee, Patricia Greninger, Jonathan H Shrimp, Wei Zhao, Ting-Yu Wei, Mi Zhou, Jason Eccleston, Jonathan Sussman, Ujjawal Manocha, Vajira Weerasekara, Hiroshi Kondo, Vindhya Vijay, Meng-Ju Wu, Sara E Kearney, Jeffrey Ho, Joseph McClanaghan, Ellen Murchie, Giovanna S Crowther, Samarjit Patnaik, Matthew B Boxer, Min Shen, David Tsai Ting, William Y Kim, Ben Z Stanger, Vikram Deshpande, Cristina R Ferrone, Cyril H Benes, Wilhelm Haas, Matthew D Hall, Nabeel El-Bardeesy
SULT1A1-dependent sulfonation of alkylators is a lineage-dependent vulnerability of liver cancers. Nature cancer (2023)
Robert Jordan, Stephanie L Ford-Scheimer, Rodolfo M Alarcon, Anthony J Atala, Jeffrey T Borenstein, Kyle R Brimacombe, Sara Cherry, Hans Clevers, Mindy I Davis, Simon G P Funnell, Lee Gehrke, Linda G Griffith, Abigail C Grossman, Thomas Hartung, Donald E Ingber, Nicole C Kleinstreuer, Calvin J Kuo, Emily M Lee, Christine L Mummery, Thames E Pickett, Sasirekha Ramani, Edwin A Rosado-Olivieri, Evi Budo Struble, Zhengpeng Wan, Mark S Williams, Matthew D Hall, Marc Ferrer, Sarine Markossian
Report of the Assay Guidance Workshop on 3-Dimensional Tissue Models for Antiviral Drug Development. The Journal of infectious diseases (2023)
Lei Shi, William Shen, Mindy I Davis, Ke Kong, Phuong Vu, Supriya K Saha, Ramzi Adil, Johannes Kreuzer, Regina Egan, Tobie D Lee, Patricia Greninger, Jonathan H Shrimp, Wei Zhao, Ting-Yu Wei, Mi Zhou, Jason Eccleston, Jonathan Sussman, Ujjawal Manocha, Vajira Weerasekara, Hiroshi Kondo, Vindhya Vijay, Meng-Ju Wu, Sara E Kearney, Jeffrey Ho, Joseph McClanaghan, Ellen Murchie, Giovanna S Crowther, Samarjit Patnaik, Matthew B Boxer, Min Shen, David Tsai Ting, William Y Kim, Ben Z Stanger, Vikram Deshpande, Cristina R Ferrone, Cyril H Benes, Wilhelm Haas, Matthew D Hall, Nabeel El-Bardeesy
SULT1A1-dependent sulfonation of alkylators is a lineage-dependent vulnerability of liver cancers. Nature cancer (2023)
Annette von Delft, Matthew D Hall, Ann D Kwong, Lisa A Purcell, Kumar Singh Saikatendu, Uli Schmitz, John A Tallarico, Alpha A Lee
Accelerating antiviral drug discovery: lessons from COVID-19. Nature reviews. Drug discovery (2023)
Quinlin M Hanson, Nate Hoxie, Min Shen, Hui Guo, Ig-Jun Cho, Ipsita Chakraborty, Brooklyn M Aragon, Ganesha Rai, Samarjit Patnaik, John S Janiszewski, Matthew D Hall
Target Class Profiling of Small-Molecule Methyltransferases. ACS chemical biology (2023)
Annette von Delft, Matthew D Hall, Ann D Kwong, Lisa A Purcell, Kumar Singh Saikatendu, Uli Schmitz, John A Tallarico, Alpha A Lee
Accelerating antiviral drug discovery: lessons from COVID-19. Nature reviews. Drug discovery (2023)
Antonella Antignani, Maria Teresa Bilotta, Jacob S Roth, Daniel J Urban, Min Shen, Matthew D Hall, David FitzGerald
Birinapant selectively enhances immunotoxin-mediated killing of cancer cells conditional on the IAP protein levels within target cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 37 (12) (2023)
Lei Shi, William Shen, Mindy I Davis, Ke Kong, Phuong Vu, Supriya K Saha, Ramzi Adil, Johannes Kreuzer, Regina Egan, Tobie D Lee, Patricia Greninger, Jonathan H Shrimp, Wei Zhao, Ting-Yu Wei, Mi Zhou, Jason Eccleston, Jonathan Sussman, Ujjawal Manocha, Vajira Weerasekara, Hiroshi Kondo, Vindhya Vijay, Meng-Ju Wu, Sara E Kearney, Jeffrey Ho, Joseph McClanaghan, Ellen Murchie, Giovanna S Crowther, Samarjit Patnaik, Matthew B Boxer, Min Shen, David Tsai Ting, William Y Kim, Ben Z Stanger, Vikram Deshpande, Cristina R Ferrone, Cyril H Benes, Wilhelm Haas, Matthew D Hall, Nabeel El-Bardeesy
SULT1A1-dependent sulfonation of alkylators is a lineage-dependent vulnerability of liver cancers. Nature cancer (2023)
Hongmao Sun, Nathan P Coussens, Carina Danchik, Leah M Wachsmuth, Mark J Henderson, Samarjit Patnaik, Matthew D Hall, Ashley L Molinaro, Dayle A Daines, Min Shen
Discovery of Small-Molecule VapC1 Nuclease Inhibitors by Virtual Screening and Scaffold Hopping from an Atomic Structure Revealing Protein-Protein Interactions with a Native VapB1 Inhibitor. Journal of chemical information and modeling 62 (5) (2022)
Victor Clausse, Yuhong Fang, Dingyin Tao, Harichandra D Tagad, Hongmao Sun, Yuhong Wang, Surendra Karavadhi, Kelly Lane, Zhen-Dan Shi, Olga Vasalatiy, Christopher A LeClair, Rebecca Eells, Min Shen, Samarjit Patnaik, Ettore Appella, Nathan P Coussens, Matthew D Hall, Daniel H Appella
Discovery of Novel Small-Molecule Scaffolds for the Inhibition and Activation of WIP1 Phosphatase from a RapidFire Mass Spectrometry High-Throughput Screen. ACS pharmacology & translational science 5 (10) (2022)
Ashley E Owens, Michael J Iannotti, Tino W Sanchez, Ty Voss, Abhijeet Kapoor, Matthew D Hall, Juan Jose Marugan, Sam Michael, Noel Southall, Mark J Henderson
High-Throughput Cellular Thermal Shift Assay Using Acoustic Transfer of Protein Lysates. ACS chemical biology 17 (2) (2022)
Jiajia Pan, Nan Li, Alex Renn, Hu Zhu, Lu Chen, Min Shen, Matthew D Hall, Min Qian, Ira H Pastan, Mitchell Ho
GPC1-Targeted Immunotoxins Inhibit Pancreatic Tumor Growth in Mice via Depletion of Short-lived GPC1 and Downregulation of Wnt Signaling. Molecular cancer therapeutics 21 (6) (2022)
Gergely Zahoránszky-Kőhalmi, Vishal B Siramshetty, Praveen Kumar, Manideep Gurumurthy, Busola Grillo, Biju Mathew, Dimitrios Metaxatos, Mark Backus, Tim Mierzwa, Reid Simon, Ivan Grishagin, Laura Brovold, Ewy A Math, Matthew D Hall, Samuel G Michael, Alexander G Godfrey, Jordi Mestres, Lars Juhl Jensen, Tudor I Oprea
A Workflow of Integrated Resources to Catalyze Network Pharmacology Driven COVID-19 Research. Journal of chemical information and modeling 62 (3) (2022)
Anup P Challa, Xin Hu, Ya-Qin Zhang, Jeffrey Hymes, Bret D Wallace, Surendra Karavadhi, Hongmao Sun, Samarjit Patnaik, Matthew D Hall, Min Shen
Virtual Screening for the Discovery of Microbiome β-Glucuronidase Inhibitors to Alleviate Cancer Drug Toxicity. Journal of chemical information and modeling 62 (7) (2022)
Ying Fu, Juliana da Fonseca Rezende E Mello, Bryan D Fleming, Alex Renn, Catherine Z Chen, Xin Hu, Miao Xu, Kirill Gorshkov, Quinlin Hanson, Wei Zheng, Emily M Lee, Lalith Perera, Robert Petrovich, Manisha Pradhan, Richard T Eastman, Zina Itkin, Thomas B Stanley, Allen L Hsu, Venkata Dandey, Kedar Sharma, William Gillette, Troy Taylor, Nitya Ramakrishnan, Shelley Perkins, Dominic Esposito, Eunkeu Oh, Kimihiro Susumu, Mason Wolak, Marc Ferrer, Matthew D Hall, Mario J Borgnia, Anton Simeonov
A humanized nanobody phage display library yields potent binders of SARS CoV-2 spike. PloS one 17 (8) (2022)
Jonathan H Shrimp, John Janiszewski, Catherine Z Chen, Miao Xu, Kelli M Wilson, Stephen C Kales, Philip E Sanderson, Paul Shinn, Rick Schneider, Zina Itkin, Hui Guo, Min Shen, Carleen Klumpp-Thomas, Samuel G Michael, Wei Zheng, Anton Simeonov, Matthew D Hall
Suite of TMPRSS2 Assays for Screening Drug Repurposing Candidates as Potential Treatments of COVID-19. ACS infectious diseases 8 (6) (2022)
Katie E Hebron, Xiaolin Wan, Jacob S Roth, David J Liewehr, Nancy E Sealover, William J E Frye, Angela Kim, Stacey Stauffer, Olivia L Perkins, Wenyue Sun, Kristine A Isanogle, Christina M Robinson, Amy James, Parirokh Awasthi, Priya Shankarappa, Xiaoling Luo, Haiyan Lei, Donna Butcher, Roberta Smith, Elijah F Edmondson, Jin-Qiu Chen, Noemi Kedei, Cody J Peer, Jack F Shern, William Douglas Figg, Lu Chen, Matthew D Hall, Simone Difilippantonio, Frederic G Barr, Robert L Kortum, Robert W Robey, Angelina V Vaseva, Javed Khan, Marielle E Yohe
The combination of trametinib and ganitumab is effective in RAS-mutated PAX-fusion negative rhabdomyosarcoma models. Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Xin Hu, Catherine Z Chen, Miao Xu, Zongyi Hu, Hui Guo, Zina Itkin, Paul Shinn, Parker Ivin, Madeleine Leek, T Jake Liang, Min Shen, Wei Zheng, Matthew D Hall
Discovery of Small Molecule Entry Inhibitors Targeting the Fusion Peptide of SARS-CoV-2 Spike Protein. ACS medicinal chemistry letters 12 (8) (2021)
Ying Fu, Juliana da Fonseca Rezende E Mello, Bryan D Fleming, Alex Renn, Catherine Z Chen, Xin Hu, Miao Xu, Kirill Gorshkov, Quinlin Hanson, Wei Zheng, Emily M Lee, Lalith Perera, Robert Petrovich, Manisha Pradhan, Richard T Eastman, Zina Itkin, Thomas Stanley, Allen Hsu, Venkata Dandey, William Gillette, Troy Taylor, Nitya Ramakrishnan, Shelley Perkins, Dominic Esposito, Eunkeu Oh, Kimihiro Susumu, Mason Wolak, Marc Ferrer, Matthew D Hall, Mario J Borgnia, Anton Simeonov
The humanized nanobody RBD-1-2G tolerates the spike N501Y mutation to neutralize SARS-CoV-2. bioRxiv : the preprint server for biology (2021)
Sankalp Jain, Daniel C Talley, Bolormaa Baljinnyam, Jun Choe, Quinlin Hanson, Wei Zhu, Miao Xu, Catherine Z Chen, Wei Zheng, Xin Hu, Min Shen, Ganesha Rai, Matthew D Hall, Anton Simeonov, Alexey V Zakharov
Hybrid In Silico Approach Reveals Novel Inhibitors of Multiple SARS-CoV-2 Variants. ACS pharmacology & translational science 4 (5) (2021)
Li Liu, Manshu Tang, Rajan Pragani, Frank G Whitby, Ya-Qin Zhang, Bijina Balakrishnan, Yuhong Fang, Surendra Karavadhi, Dingyin Tao, Christopher A LeClair, Matthew D Hall, Juan Jose Marugan, Matthew Boxer, Min Shen, Christopher P Hill, Kent Lai, Samarjit Patnaik
Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors. Journal of medicinal chemistry 64 (18) (2021)
Jason M Rohde, Surendra Karavadhi, Rajan Pragani, Li Liu, Yuhong Fang, Weihe Zhang, Andrew McIver, Hongchao Zheng, Qingyang Liu, Mindy I Davis, Daniel J Urban, Tobie D Lee, Dorian M Cheff, Melinda Hollingshead, Mark J Henderson, Natalia J Martinez, Kyle R Brimacombe, Adam Yasgar, Wei Zhao, Carleen Klumpp-Thomas, Sam Michael, Joseph Covey, William J Moore, Gordon M Stott, Zhuyin Li, Anton Simeonov, Ajit Jadhav, Stephen V Frye, Matthew D Hall, Min Shen, Xiaodong Wang, Samarjit Patnaik, Matthew B Boxer
Discovery and Optimization of 2H-1λ2-Pyridin-2-one Inhibitors of Mutant Isocitrate Dehydrogenase 1 for the Treatment of Cancer. Journal of medicinal chemistry 64 (8) (2021)
Heather Kalish, Carleen Klump-Thomas, Sally Hunsberger, Holly Ann Baus, Michael P Fay, Nalyn Siripong, Jing Wang, Jennifer Hicks, Jennifer Mehalko, Jameson Travers, Matthew Drew, Kyle Pauly, Jacquelyn Spathies, Tran B Ngo, Kenneth M Adusei, Maria Karkanitsa, Jennifer A Croker, Yan Li, Barry I Graubard, Lindsay Czajkowski, Olivia Belliveau, Cheryl Chairez, Kelly R Snead, Peter J Frank, Anandakumar Shunmugavel, Alison Han, Luca Tudor Giurgea, Luz Angela Rosas, Rachel Bean, Rani Athota, Adriana Cervantes-Medina, Monica Gouzoulis, Brittany Heffelfinger, Shannon Valenti, Rocco Caldararo, Michelle M Kolberg, Andrew Kelly, Reid Simon, Saifullah Shafiq, Vanessa E Wall, Susan Reed, Eric W Ford, Ravi Lokwani, John-Paul Denson, Simon Messing, Samuel Michael, William K Gillette, Robert P Kimberly, Steven E Reis, Matthew D Hall, Dominic Esposito, Matthew J Memoli, Kaitlyn Sadtler
Undiagnosed SARS-CoV-2 seropositivity during the first 6 months of the COVID-19 pandemic in the United States. Science translational medicine 13 (601) (2021)
Jianping Li, Julia Hlavka-Zhang, Jonathan H Shrimp, Crissandra Piper, Daphne Dupere-Richer, Jacob S Roth, Duohui Jing, Heidi L Casellas Roman, Catalina Troche, Alok Swaroop, Marta Kulis, Jon A Oyer, Christine M Will, Min Shen, Alberto Riva, Richard L Bennett, Adolfo A Ferrando, Matthew D Hall, Richard B Lock, Jonathan D Licht
PRC2 Inhibitors Overcome Glucocorticoid Resistance Driven by NSD2 Mutation in Pediatric Acute Lymphoblastic Leukemia. Cancer discovery (2021)
Andrew P Burns, Ya-Qin Zhang, Tuan Xu, Zhengxi Wei, Qin Yao, Yuhong Fang, Valeriu Cebotaru, Menghang Xia, Matthew D Hall, Ruili Huang, Anton Simeonov, Christopher A LeClair, Dingyin Tao
A Universal and High-Throughput Proteomics Sample Preparation Platform. Analytical chemistry 93 (24) (2021)
Ruili Huang, Miao Xu, Hu Zhu, Catherine Z Chen, Wei Zhu, Emily M Lee, Shihua He, Li Zhang, Jinghua Zhao, Khalida Shamim, Danielle Bougie, Wenwei Huang, Menghang Xia, Matthew D Hall, Donald Lo, Anton Simeonov, Christopher P Austin, Xiangguo Qiu, Hengli Tang, Wei Zheng
Biological activity-based modeling identifies antiviral leads against SARS-CoV-2. Nature biotechnology 39 (6) (2021)
Zachary F Caffall, Bradley J Wilkes, Ricardo Hernández-Martinez, Joseph E Rittiner, Jennifer T Fox, Kanny K Wan, Miranda K Shipman, Steven A Titus, Ya-Qin Zhang, Samarjit Patnaik, Matthew D Hall, Matthew B Boxer, Min Shen, Zhuyin Li, David E Vaillancourt, Nicole Calakos
The HIV protease inhibitor, ritonavir, corrects diverse brain phenotypes across development in mouse model of DYT-TOR1A dystonia. Science translational medicine 13 (607) (2021)
Xin Hu, Jonathan H Shrimp, Hui Guo, Miao Xu, Catherine Z Chen, Wei Zhu, Alexey V Zakharov, Sankalp Jain, Paul Shinn, Anton Simeonov, Matthew D Hall, Min Shen
Discovery of TMPRSS2 Inhibitors from Virtual Screening as a Potential Treatment of COVID-19. ACS pharmacology & translational science 4 (3) (2021)
Lyn M Huff, Sachi Horibata, Robert W Robey, Matthew D Hall, Michael M Gottesman
Mycoplasma Infection Mediates Sensitivity of Multidrug-Resistant Cell Lines to Tiopronin: A Cautionary Tale. Journal of medicinal chemistry 63 (3) (2020)
Theresa D Manz, Sindhu Carmen Sivakumaren, Fleur M Ferguson, Tinghu Zhang, Adam Yasgar, Hyuk-Soo Seo, Scott B Ficarro, Joseph D Card, Hyeseok Shim, Chandrasekhar V Miduturu, Anton Simeonov, Min Shen, Jarrod A Marto, Sirano Dhe-Paganon, Matthew D Hall, Lewis C Cantley, Nathanael S Gray
Discovery and Structure-Activity Relationship Study of (Z)-5-Methylenethiazolidin-4-one Derivatives as Potent and Selective Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors. Journal of medicinal chemistry 63 (9) (2020)
Ganesha Rai, Daniel J Urban, Bryan T Mott, Xin Hu, Shyh-Ming Yang, Gloria A Benavides, Michelle S Johnson, Giuseppe L Squadrito, Kyle R Brimacombe, Tobie D Lee, Dorian M Cheff, Hu Zhu, Mark J Henderson, Katherine Pohida, Gary A Sulikowski, David M Dranow, Md Kabir, Pranav Shah, Elias Padilha, Dingyin Tao, Yuhong Fang, Plamen P Christov, Kwangho Kim, Somnath Jana, Pavan Muttil, Tamara Anderson, Nitesh K Kunda, Helen J Hathaway, Donna F Kusewitt, Nobu Oshima, Murali Cherukuri, Douglas R Davies, Jeffrey P Norenberg, Larry A Sklar, William J Moore, Chi V Dang, Gordon M Stott, Leonard Neckers, Andrew J Flint, Victor M Darley-Usmar, Anton Simeonov, Alex G Waterson, Ajit Jadhav, Matthew D Hall, David J Maloney
Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties. Journal of medicinal chemistry 63 (19) (2020)
Ruili Huang, Miao Xu, Hu Zhu, Catherine Z Chen, Emily M Lee, Shihua He, Khalida Shamim, Danielle Bougie, Wenwei Huang, Matthew D Hall, Donald Lo, Anton Simeonov, Christopher P Austin, Xiangguo Qiu, Hengli Tang, Wei Zheng
Massive-scale biological activity-based modeling identifies novel antiviral leads against SARS-CoV-2. bioRxiv : the preprint server for biology (2020)
Rachel P M Abrams, Adam Yasgar, Tadahisa Teramoto, Myoung-Hwa Lee, Dorjbal Dorjsuren, Richard T Eastman, Nasir Malik, Alexey V Zakharov, Wenxue Li, Muzna Bachani, Kyle Brimacombe, Joseph P Steiner, Matthew D Hall, Anuradha Balasubramanian, Ajit Jadhav, Radhakrishnan Padmanabhan, Anton Simeonov, Avindra Nath
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. Proceedings of the National Academy of Sciences of the United States of America 117 (49) (2020)
Jonathan H Shrimp, Stephen C Kales, Philip E Sanderson, Anton Simeonov, Min Shen, Matthew D Hall
An Enzymatic TMPRSS2 Assay for Assessment of Clinical Candidates and Discovery of Inhibitors as Potential Treatment of COVID-19. bioRxiv : the preprint server for biology (2020)
Jacob S Roth, Tobie D Lee, Dorian M Cheff, Maya L Gosztyla, Rosita R Asawa, Carina Danchik, Sam Michael, Anton Simeonov, Carleen Klumpp-Thomas, Kelli M Wilson, Matthew D Hall
Keeping It Clean: The Cell Culture Quality Control Experience at the National Center for Advancing Translational Sciences. SLAS discovery : advancing life sciences R & D 25 (5) (2020)
Carleen Klump-Thomas, Heather Kalish, Jennifer Hicks, Jennifer Mehalko, Matthew Drew, Matthew J Memoli, Matthew D Hall, Dominic Esposito, Kaitlyn Sadtler
D614G Spike Variant Does Not Alter IgG, IgM, or IgA Spike Seroassay Performance. medRxiv : the preprint server for health sciences (2020)
Kirill Gorshkov, Catherine Z Chen, Robert Bostwick, Lynn Rasmussen, Bruce Nguyen Tran, Yu-Shan Cheng, Miao Xu, Manisha Pradhan, Mark J Henderson, Wei Zhu, Eunkeu Oh, Kimihiro Susumu, Mason Wolak, Khalida Shamim, Wenwei Huang, Xin Hu, Min Shen, Carleen Klumpp-Thomas, Zina Itkin, Paul Shinn, Juan Carlos de la Torre, Anton Simeonov, Sam G Michael, Matthew D Hall, Donald C Lo, Wei Zheng
The SARS-CoV-2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules. ACS infectious diseases 7 (6) (2020)
Kyle R Brimacombe, Tongan Zhao, Richard T Eastman, Xin Hu, Ke Wang, Mark Backus, Bolormaa Baljinnyam, Catherine Z Chen, Lu Chen, Tara Eicher, Marc Ferrer, Ying Fu, Kirill Gorshkov, Hui Guo, Quinlin M Hanson, Zina Itkin, Stephen C Kales, Carleen Klumpp-Thomas, Emily M Lee, Sam Michael, Tim Mierzwa, Andrew Patt, Manisha Pradhan, Alex Renn, Paul Shinn, Jonathan H Shrimp, Amit Viraktamath, Kelli M Wilson, Miao Xu, Alexey V Zakharov, Wei Zhu, Wei Zheng, Anton Simeonov, Ewy A Mathé, Donald C Lo, Matthew D Hall, Min Shen
An OpenData portal to share COVID-19 drug repurposing data in real time. bioRxiv : the preprint server for biology (2020)
Neeladri Sekhar Roy, Xiaoying Jian, Olivier Soubias, Peng Zhai, Jessica R Hall, Jessica N Dagher, Nathan P Coussens, Lisa M Miller Jenkins, Ruibai Luo, Itoro O Akpan, Matthew D Hall, R Andrew Byrd, Marielle E Yohe, Paul A Randazzo
Interaction of the N terminus of ADP-ribosylation factor with the PH domain of the GTPase-activating protein ASAP1 requires phosphatidylinositol 4,5-bisphosphate. The Journal of biological chemistry 294 (46) (2019)
Hu Zhu, Olivia W Lee, Pranav Shah, Ajit Jadhav, Xin Xu, Samarjit Patnaik, Min Shen, Matthew D Hall
Identification of Activators of Human Fumarate Hydratase by Quantitative High-Throughput Screening. SLAS discovery : advancing life sciences R & D 25 (1) (2019)
Choh Yeung, Anna E Gibson, Sameer H Issaq, Nobu Oshima, Joshua T Baumgart, Leah D Edessa, Ganesha Rai, Daniel J Urban, Michelle S Johnson, Gloria A Benavides, Giuseppe L Squadrito, Marielle E Yohe, Haiyan Lei, Sandy Eldridge, John Hamre, Tyrone Dowdy, Victor Ruiz-Rodado, Adrian Lita, Arnulfo Mendoza, Jack F Shern, Mioara Larion, Lee J Helman, Gordon M Stott, Murali C Krishna, Matthew D Hall, Victor Darley-Usmar, Leonard M Neckers, Christine M Heske
Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma. Cancer research 79 (19) (2019)
Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology 96 (5) (2019)
Robert W Robey, Kristen M Pluchino, Matthew D Hall, Antonio T Fojo, Susan E Bates, Michael M Gottesman
Revisiting the role of ABC transporters in multidrug-resistant cancer. Nature reviews. Cancer 18 (7) (2019)
Victor Clausse, Dingyin Tao, Subrata Debnath, Yuhong Fang, Harichandra D Tagad, Yuhong Wang, Hongmao Sun, Christopher A LeClair, Sharlyn J Mazur, Kelly Lane, Zhen-Dan Shi, Olga Vasalatiy, Rebecca Eells, Lynn K Baker, Mark J Henderson, Martin R Webb, Min Shen, Matthew D Hall, Ettore Appella, Daniel H Appella, Nathan P Coussens
Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens. The Journal of biological chemistry 294 (46) (2019)
Sarah Wang, Elizabeth E Hwang, Rajarshi Guha, Allison F O'Neill, Nicole Melong, Chansey J Veinotte, Amy Conway Saur, Kellsey Wuerthele, Min Shen, Crystal McKnight, Gabriela Alexe, Madeleine E Lemieux, Amy Wang, Emma Hughes, Xin Xu, Matthew B Boxer, Matthew D Hall, Andrew Kung, Jason N Berman, Mindy I Davis, Kimberly Stegmaier, Brian D Crompton
High-throughput Chemical Screening Identifies Focal Adhesion Kinase and Aurora Kinase B Inhibition as a Synergistic Treatment Combination in Ewing Sarcoma. Clinical cancer research : an official journal of the American Association for Cancer Research 25 (14) (2019)
Olivia W Lee, Shelley Austin, Madison Gamma, Dorian M Cheff, Tobie D Lee, Kelli M Wilson, Joseph Johnson, Jameson Travers, John C Braisted, Rajarshi Guha, Carleen Klumpp-Thomas, Min Shen, Matthew D Hall
Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. SLAS discovery : advancing life sciences R & D 25 (1) (2019)
John R Horton, Clayton B Woodcock, Qin Chen, Xu Liu, Xing Zhang, John Shanks, Ganesha Rai, Bryan T Mott, Daniel J Jansen, Stephen C Kales, Mark J Henderson, Matthew Cyr, Katherine Pohida, Xin Hu, Pranav Shah, Xin Xu, Ajit Jadhav, David J Maloney, Matthew D Hall, Anton Simeonov, Haian Fu, Paula M Vertino, Xiaodong Cheng
Structure-Based Engineering of Irreversible Inhibitors against Histone Lysine Demethylase KDM5A. Journal of medicinal chemistry 61 (23) (2018)
Natalia J Martinez, Rosita R Asawa, Matthew G Cyr, Alexey Zakharov, Daniel J Urban, Jacob S Roth, Eric Wallgren, Carleen Klumpp-Thomas, Nathan P Coussens, Ganesha Rai, Shyh-Ming Yang, Matthew D Hall, Juan J Marugan, Anton Simeonov, Mark J Henderson
A widely-applicable high-throughput cellular thermal shift assay (CETSA) using split Nano Luciferase. Scientific reports 8 (1) (2018)
John R Horton, Xu Liu, Lizhen Wu, Kai Zhang, John Shanks, Xing Zhang, Ganesha Rai, Bryan T Mott, Daniel J Jansen, Stephen C Kales, Mark J Henderson, Katherine Pohida, Yuhong Fang, Xin Hu, Ajit Jadhav, David J Maloney, Matthew D Hall, Anton Simeonov, Haian Fu, Paula M Vertino, Qin Yan, Xiaodong Cheng
Insights into the Action of Inhibitor Enantiomers against Histone Lysine Demethylase 5A. Journal of medicinal chemistry 61 (7) (2018)
Dorian M Cheff, Matthew D Hall
Correction to A Drug of Such Damned Nature. Challenges and Opportunities in Translational Platinum Drug Research. Journal of medicinal chemistry 61 (19) (2018)
Nathan P Coussens, Stephen C Kales, Mark J Henderson, Olivia W Lee, Kurumi Y Horiuchi, Yuren Wang, Qing Chen, Ekaterina Kuznetsova, Jianghong Wu, Sirisha Chakka, Dorian M Cheff, Ken Chih-Chien Cheng, Paul Shinn, Kyle R Brimacombe, Min Shen, Anton Simeonov, Madhu Lal-Nag, Haiching Ma, Ajit Jadhav, Matthew D Hall
High-throughput screening with nucleosome substrate identifies small-molecule inhibitors of the human histone lysine methyltransferase NSD2. The Journal of biological chemistry 293 (35) (2018)
Andrew M Breglio, Aaron E Rusheen, Eric D Shide, Katharine A Fernandez, Katie K Spielbauer, Katherine M McLachlin, Matthew D Hall, Lauren Amable, Lisa L Cunningham
Cisplatin is retained in the cochlea indefinitely following chemotherapy. Nature communications 8 (1) (2017)
Daniel J Urban, Natalia J Martinez, Mindy I Davis, Kyle R Brimacombe, Dorian M Cheff, Tobie D Lee, Mark J Henderson, Steven A Titus, Rajan Pragani, Jason M Rohde, Li Liu, Yuhong Fang, Surendra Karavadhi, Pranav Shah, Olivia W Lee, Amy Wang, Andrew McIver, Hongchao Zheng, Xiaodong Wang, Xin Xu, Ajit Jadhav, Anton Simeonov, Min Shen, Matthew B Boxer, Matthew D Hall
Assessing inhibitors of mutant isocitrate dehydrogenase using a suite of pre-clinical discovery assays. Scientific reports 7 (1) (2017)
Dorian M Cheff, Matthew D Hall
A Drug of Such Damned Nature.1 Challenges and Opportunities in Translational Platinum Drug Research. Journal of medicinal chemistry 60 (11) (2017)
Ganesha Rai, Kyle R Brimacombe, Bryan T Mott, Daniel J Urban, Xin Hu, Shyh-Ming Yang, Tobie D Lee, Dorian M Cheff, Jennifer Kouznetsova, Gloria A Benavides, Katie Pohida, Eric J Kuenstner, Diane K Luci, Christine M Lukacs, Douglas R Davies, David M Dranow, Hu Zhu, Gary Sulikowski, William J Moore, Gordon M Stott, Andrew J Flint, Matthew D Hall, Victor M Darley-Usmar, Leonard M Neckers, Chi V Dang, Alex G Waterson, Anton Simeonov, Ajit Jadhav, David J Maloney
Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH). Journal of medicinal chemistry 60 (22) (2017)

Matthew D Hall.css-eqlu8i{font-size:small;padding-left:4px;} (Matthew Hall, Mathew D Hall)

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Matthew D Hall (Matthew Hall, Mathew D Hall)