Ryan D Chow

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 20

Top Topics

Breast Cancer Risk

Gene Expression

Dna Damage Response

Top Venues

medRxiv : the preprint server for health sciences

Nature biotechnology

Nature communications

Nature immunology

This page only lists publications with an associated author ORCID identifier.

Publications

Ryan D Chow, Ravi B Parikh, Katherine L Nathanson
Real-world evaluation of deep learning algorithms to classify functional pathogenic germline variants. medRxiv : the preprint server for health sciences (2024)
Ryan D Chow, Ravi B Parikh, Katherine L Nathanson
Real-world evaluation of deep learning algorithms to classify functional pathogenic germline variants. medRxiv : the preprint server for health sciences (2024)
Ryan D Chow, Ravi B Parikh, Katherine L Nathanson
Real-world evaluation of deep learning algorithms to classify functional pathogenic germline variants. medRxiv : the preprint server for health sciences (2024)
Xiaoyu Zhou, Hanbing Cao, Shao-Yu Fang, Ryan D Chow, Kaiyuan Tang, Medha Majety, Meizhu Bai, Matthew B Dong, Paul A Renauer, Xingbo Shang, Kazushi Suzuki, Andre Levchenko, Sidi Chen
CTLA-4 tail fusion enhances CAR-T antitumor immunity. Nature immunology (2023)
Xiaoyun Dai, Jonathan J Park, Ya-Ying Du, Zhenkun Na, Stanley Z Lam, Ryan D Chow, Paul A Renauer, Jianlei Gu, Shan Xin, Zhiyuan Chu, Cun Liao, Paul Clark, Hongyu Zhao, Sarah A Slavoff, Sidi Chen
Massively parallel knock-in engineering of human T cells. Nature biotechnology (2023)
Jennifer S Chen, Ryan D Chow, Eric Song, Tianyang Mao, Benjamin Israelow, Kathy Kamath, Joel Bozekowski, Winston A Haynes, Renata B Filler, Bridget L Menasché, Jin Wei, Mia Madel Alfajaro, Wenzhi Song, Lei Peng, Lauren Carter, Jason S Weinstein, Uthaman Gowthaman, Sidi Chen, Joseph E Craft, John C Shon, Akiko Iwasak, Craig B Wilen, Stephanie C Eisenbarth
High-affinity, neutralizing antibodies to SARS-CoV-2 can be made without T follicular helper cells. Science immunology 7 (68) (2022)
Lei Peng, Yingxia Hu, Madeleine C Mankowski, Ping Ren, Rita E Chen, Jin Wei, Min Zhao, Tongqing Li, Therese Tripler, Lupeng Ye, Ryan D Chow, Zhenhao Fang, Chunxiang Wu, Matthew B Dong, Matthew Cook, Guilin Wang, Paul Clark, Bryce Nelson, Daryl E Klein, Richard Sutton, Michael S. Diamond, Craig B Wilen, Yong Xiong, Sidi Chen
Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617. Nature communications 13 (1) (2022)
Ryan D Chow, Tai Michaels, Stefania Bellone, Tobias Mp Hartwich, Elena Bonazzoli, Akiko Iwasak, Eric Song, Alessandro D Santin
Distinct mechanisms of mismatch repair deficiency delineate two modes of response to PD-1 immunotherapy in endometrial carcinoma. Cancer discovery (2022)
Ryan D Chow, Medha Majety, Sidi Chen
The aging transcriptome and cellular landscape of the human lung in relation to SARS-CoV-2. Nature communications 12 (1) (2021)
Neal G Ravindra, Mia Madel Alfajaro, Victor Gasque, Nicholas C Huston, Han Wan, Klara Szigeti-Buck, Yuki Yasumoto, Allison M Greaney, Victoria Habet, Ryan D Chow, Jennifer S Chen, Jin Wei, Renata B Filler, Bao Wang, Guilin Wang, Laura E Niklason, Ruth Rebecca Montgomery, Stephanie C Eisenbarth, Sidi Chen, Adam Williams, Akiko Iwasaki, Tamas L Horvath, Ellen F Foxman, Richard W Pierce, Anna Marie Pyle, David van Dijk, Craig B Wilen
Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes. PLoS biology 19 (3) (2021)
Ryan D Chow
On the Absence of Sound. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 39 (33) (2021)
Elise Alspach, Ryan D Chow, Shadhmer Demehri, Jennifer L Guerriero, Shashi Gujar, Felix J Hartmann, Beth A Helmink, William H Hudson, Won Jin Ho, Leyuan Ma, Barbara B Maier, Vivien I Maltez, Brian C Miller, Amy E Moran, Erin M Parry, Padmini S Pillai, Sarwish Rafiq, Miguel Reina-Campos, Pamela C Rosato, Nils-Petter Rudqvist, Megan K Ruhland, Idit Sagiv-Barfi, Avinash Das Sahu, Robert M Samstein, Christian M Schürch, Debattama R Sen, Daniela S Thommen, Yochai Wolf, Roberta Zappasodi
Supporting the Next Generation of Scientists to Lead Cancer Immunology Research. Cancer immunology research 9 (11) (2021)
Guangchuan Wang, Ryan D Chow, Lvyun Zhu, Zhigang Bai, Lupeng Ye, Feifei Zhang, Paul A Renauer, Matthew B Dong, Xiaoyun Dai, Xiaoya Zhang, Ya-Ying Du, Yujing Cheng, Leilei Niu, Zhiyuan Chu, Kristin Kim, Cun Liao, Paul Clark, Youssef Errami, Sidi Chen
CRISPR-GEMM Pooled Mutagenic Screening Identifies KMT2D as a Major Modulator of Immune Checkpoint Blockade. Cancer discovery 10 (12) (2020)
Ryan D Chow, Jennifer S Chen, Johanna Shen, Sidi Chen
A web tool for the design of prime-editing guide RNAs. Nature biomedical engineering 5 (2) (2020)
Lupeng Ye, Jonathan J Park, Matthew B Dong, Quanjun Yang, Ryan D Chow, Lei Peng, Ya-Ying Du, Jianjian Guo, Xiaoyun Dai, Guangchuan Wang, Youssef Errami, Sidi Chen
In vivo CRISPR screening in CD8 T cells with AAV-Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma. Nature biotechnology 37 (11) (2019)
Ryan D Chow, Guangchuan Wang, Lupeng Ye, Adan Codina, Hyunu Ray Kim, Li Shen, Matthew B Dong, Youssef Errami, Sidi Chen
In vivo profiling of metastatic double knockouts through CRISPR-Cpf1 screens. Nature methods 16 (5) (2019)
Guangchuan Wang, Ryan D Chow, Zhigang Bai, Lvyun Zhu, Youssef Errami, Xiaoyun Dai, Matthew B Dong, Lupeng Ye, Xiaoya Zhang, Paul A Renauer, Jonathan J Park, Li Shen, Hanghui Ye, Charles S Fuchs, Sidi Chen
Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity. Nature immunology 20 (11) (2019)
Guangchuan Wang, Ryan D Chow, Lupeng Ye, Christopher D Guzman, Xiaoyun Dai, Matthew B Dong, Feng Zhang, Phillip A Sharp, Randall J Platt, Sidi Chen
Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR-mediated direct in vivo screening. Science advances 4 (2) (2018)
Ryan D Chow, Sidi Chen
Sno-derived RNAs are prevalent molecular markers of cancer immunity. Oncogene 37 (50) (2018)
Ryan D Chow, Christopher D Guzman, Guangchuan Wang, Florian Schmidt, Mark W Youngblood, Lupeng Ye, Youssef Errami, Matthew B Dong, Michael A Martinez, Sensen Zhang, Paul Renauer, Kaya Bilguvar, Murat Gunel, Phillip A Sharp, Feng Zhang, Randall J Platt, Sidi Chen
AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma. Nature neuroscience 20 (10) (2017)