Sabine Willems

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 13

Top Topics

Blood Brain Barrier

Transcription Factor

Structure Activity Relationship

Cognitive Impairment

Top Venues

Journal of medicinal chemistry

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

This page only lists publications with an associated author ORCID identifier.

Publications

Max Lewandowski, Melania Carmina, Loris Knümann, Minh Sai, Sabine Willems, Till Kasch, Julius Pollinger, Stefan Knapp, Julian A Marschner, Apirat Chaikuad, Daniel Merk
Structure-Guided Design of a Highly Potent Partial RXR Agonist with Superior Physicochemical Properties. Journal of medicinal chemistry 67 (3) (2024)
Sabine Willems, Romy Busch, Felix Nawa, Marco Ballarotto, Felix F Lillich, Till Kasch, Úrsula López-García, Julian A Marschner, Lorena A Rüger, Beatrice Renelt, Julia Ohrndorf, Silvia Arifi, Daniel Zaienne, Ewgenij Proschak, Jörg Pabel, Daniel Merk
Structural Optimization of Oxaprozin for Selective Inverse Nurr1 Agonism. Journal of medicinal chemistry 67 (15) (2024)
Sabine Willems, Romy Busch, Felix Nawa, Marco Ballarotto, Felix F Lillich, Till Kasch, Úrsula López-García, Julian A Marschner, Lorena A Rüger, Beatrice Renelt, Julia Ohrndorf, Silvia Arifi, Daniel Zaienne, Ewgenij Proschak, Jörg Pabel, Daniel Merk
Structural Optimization of Oxaprozin for Selective Inverse Nurr1 Agonism. Journal of medicinal chemistry 67 (15) (2024)
Max Lewandowski, Melania Carmina, Loris Knümann, Minh Sai, Sabine Willems, Till Kasch, Julius Pollinger, Stefan Knapp, Julian A Marschner, Apirat Chaikuad, Daniel Merk
Structure-Guided Design of a Highly Potent Partial RXR Agonist with Superior Physicochemical Properties. Journal of medicinal chemistry (2024)
Max Lewandowski, Melania Carmina, Loris Knümann, Minh Sai, Sabine Willems, Till Kasch, Julius Pollinger, Stefan Knapp, Julian A Marschner, Apirat Chaikuad, Daniel Merk
Structure-Guided Design of a Highly Potent Partial RXR Agonist with Superior Physicochemical Properties. Journal of medicinal chemistry 67 (3) (2024)
Sabine Willems, Romy Busch, Felix Nawa, Marco Ballarotto, Felix F Lillich, Till Kasch, Úrsula López-García, Julian A Marschner, Lorena A Rüger, Beatrice Renelt, Julia Ohrndorf, Silvia Arifi, Daniel Zaienne, Ewgenij Proschak, Jörg Pabel, Daniel Merk
Structural Optimization of Oxaprozin for Selective Inverse Nurr1 Agonism. Journal of medicinal chemistry (2024)
Marco Ballarotto, Sabine Willems, Tanja Stiller, Felix Nawa, Julian A Marschner, Francesca Grisoni, Daniel Merk
De Novo Design of Nurr1 Agonists via Fragment-Augmented Generative Deep Learning in Low-Data Regime. Journal of medicinal chemistry (2023)
Gustave Adouvi, Felix Nawa, Marco Ballarotto, Lorena Andrea Rüger, Loris Knümann, Till Kasch, Silvia Arifi, Manfred Schubert-Zsilavecz, Sabine Willems, Julian A Marschner, Jörg Pabel, Daniel Merk
Structural Fusion of Natural and Synthetic Ligand Features Boosts RXR Agonist Potency. Journal of medicinal chemistry (2023)
Sabine Willems, Daniel Merk
Medicinal Chemistry and Chemical Biology of Nurr1 Modulators: An Emerging Strategy in Neurodegeneration. Journal of medicinal chemistry 65 (14) (2022)
Sabine Willems, Marcel Müller, Julia Ohrndorf, Jan Heering, Ewgenij Proschak, Daniel Merk
Scaffold Hopping from Amodiaquine to Novel Nurr1 Agonist Chemotypes via Microscale Analogue Libraries. ChemMedChem 17 (8) (2022)
Sabine Willems, Julian A Marschner, Whitney Kilu, Giuseppe Faudone, Romy Busch, Silke Duensing-Kropp, Jan Heering, Daniel Merk
Nurr1 Modulation Mediates Neuroprotective Effects of Statins. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 9 (18) (2022)
Felix F Lillich, Sabine Willems, Xiaomin Ni, Whitney Kilu, Carmen Borkowsky, Mirko Brodsky, Jan S Kramer, Steffen Brunst, Victor Hernandez-Olmos, Jan Heering, Simone Schierle, Roxane-I Kestner, Franziska M Mayser, Moritz Helmstädter, Tamara Göbel, Lilia Weizel, Dmitry Namgaladze, Astrid Kaiser, Dieter Steinhilber, Waltraud Pfeilschifter, Astrid S Kahnt, Anna Proschak, Apirat Chaikuad, Stefan Knapp, Daniel Merk, Ewgenij Proschak
Structure-Based Design of Dual Partial Peroxisome Proliferator-Activated Receptor γ Agonists/Soluble Epoxide Hydrolase Inhibitors. Journal of medicinal chemistry 64 (23) (2021)
Daniel Zaienne, Sabine Willems, Simone Schierle, Jan Heering, Daniel Merk
Development and Profiling of Inverse Agonist Tools for the Neuroprotective Transcription Factor Nurr1. Journal of medicinal chemistry 64 (20) (2021)