Jan Heering

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 20

Top Topics

Transcription Factor

Top Venues

Journal of medicinal chemistry

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

ACS pharmacology & translational science

This page only lists publications with an associated author ORCID identifier.

Publications

Annika Balzulat, W Felix Zhu, Cathrin Flauaus, Victor Hernandez-Olmos, Jan Heering, Sunesh Sethumadhavan, Mariam Dubiel, Annika Frank, Amelie Menge, Maureen Hebchen, Katharina Metzner, Ruirui Lu, Robert Lukowski, Peter Ruth, Stefan Knapp, Susanne Müller, Dieter Steinhilber, Inga Hänelt, Holger Stark, Ewgenij Proschak, Achim Schmidtko
Discovery of a Small Molecule Activator of Slack (Kcnt1) Potassium Channels That Significantly Reduces Scratching in Mouse Models of Histamine-Independent and Chronic Itch. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2024)
Annika Balzulat, W Felix Zhu, Cathrin Flauaus, Victor Hernandez-Olmos, Jan Heering, Sunesh Sethumadhavan, Mariam Dubiel, Annika Frank, Amelie Menge, Maureen Hebchen, Katharina Metzner, Ruirui Lu, Robert Lukowski, Peter Ruth, Stefan Knapp, Susanne Müller, Dieter Steinhilber, Inga Hänelt, Holger Stark, Ewgenij Proschak, Achim Schmidtko
Discovery of a Small Molecule Activator of Slack (Kcnt1) Potassium Channels That Significantly Reduces Scratching in Mouse Models of Histamine-Independent and Chronic Itch. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (15) (2024)
Annika Balzulat, W Felix Zhu, Cathrin Flauaus, Victor Hernandez-Olmos, Jan Heering, Sunesh Sethumadhavan, Mariam Dubiel, Annika Frank, Amelie Menge, Maureen Hebchen, Katharina Metzner, Ruirui Lu, Robert Lukowski, Peter Ruth, Stefan Knapp, Susanne Müller, Dieter Steinhilber, Inga Hänelt, Holger Stark, Ewgenij Proschak, Achim Schmidtko
Discovery of a Small Molecule Activator of Slack (Kcnt1) Potassium Channels That Significantly Reduces Scratching in Mouse Models of Histamine-Independent and Chronic Itch. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (15) (2024)
Annika Balzulat, W Felix Zhu, Cathrin Flauaus, Victor Hernandez-Olmos, Jan Heering, Sunesh Sethumadhavan, Mariam Dubiel, Annika Frank, Amelie Menge, Maureen Hebchen, Katharina Metzner, Ruirui Lu, Robert Lukowski, Peter Ruth, Stefan Knapp, Susanne Müller, Dieter Steinhilber, Inga Hänelt, Holger Stark, Ewgenij Proschak, Achim Schmidtko
Discovery of a Small Molecule Activator of Slack (Kcnt1) Potassium Channels That Significantly Reduces Scratching in Mouse Models of Histamine-Independent and Chronic Itch. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (15) (2024)
Annika Balzulat, W Felix Zhu, Cathrin Flauaus, Victor Hernandez-Olmos, Jan Heering, Sunesh Sethumadhavan, Mariam Dubiel, Annika Frank, Amelie Menge, Maureen Hebchen, Katharina Metzner, Ruirui Lu, Robert Lukowski, Peter Ruth, Stefan Knapp, Susanne Müller, Dieter Steinhilber, Inga Hänelt, Holger Stark, Ewgenij Proschak, Achim Schmidtko
Discovery of a Small Molecule Activator of Slack (Kcnt1) Potassium Channels That Significantly Reduces Scratching in Mouse Models of Histamine-Independent and Chronic Itch. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (15) (2024)
Annika Balzulat, W Felix Zhu, Cathrin Flauaus, Victor Hernandez-Olmos, Jan Heering, Sunesh Sethumadhavan, Mariam Dubiel, Annika Frank, Amelie Menge, Maureen Hebchen, Katharina Metzner, Ruirui Lu, Robert Lukowski, Peter Ruth, Stefan Knapp, Susanne Müller, Dieter Steinhilber, Inga Hänelt, Holger Stark, Ewgenij Proschak, Achim Schmidtko
Discovery of a Small Molecule Activator of Slack (Kcnt1) Potassium Channels That Significantly Reduces Scratching in Mouse Models of Histamine-Independent and Chronic Itch. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (15) (2024)
Felix Nawa, Minh Sai, Jan Vietor, Roman Schwarzenbach, Anesa Bitić, Sina Wolff, Niklas Ildefeld, Jörg Pabel, Thomas Wein, Julian A Marschner, Jan Heering, Daniel Merk
Tuning RXR Modulators for PGC1α Recruitment. Journal of medicinal chemistry (2024)
Silvia Arifi, Julian A Marschner, Julius Pollinger, Laura Isigkeit, Pascal Heitel, Astrid Kaiser, Lennart Obeser, Georg Höfner, Ewgenij Proschak, Stefan Knapp, Apirat Chaikuad, Jan Heering, Daniel Merk
Targeting the Alternative Vitamin E Metabolite Binding Site Enables Noncanonical PPARγ Modulation. Journal of the American Chemical Society (2023)
Sabine Willems, Marcel Müller, Julia Ohrndorf, Jan Heering, Ewgenij Proschak, Daniel Merk
Scaffold Hopping from Amodiaquine to Novel Nurr1 Agonist Chemotypes via Microscale Analogue Libraries. ChemMedChem 17 (8) (2022)
Jan Heering, Victor Hernandez-Olmos, Niklas Ildefeld, Ting Liu, Anja Kaiser, Zumer Naeem, Timo Frömel, Ingrid Fleming, Dieter Steinhilber, Ewgenij Proschak
Development and Characterization of a Fluorescent Ligand for Leukotriene B4 Receptor 2 in Cells and Tissues. Journal of medicinal chemistry 65 (3) (2022)
Giuseppe Faudone, Rezart Zhubi, Fatih Celik, Stefan Knapp, Apirat Chaikuad, Jan Heering, Daniel Merk
Design of a Potent TLX Agonist by Rational Fragment Fusion. Journal of medicinal chemistry 65 (3) (2022)
Jan Heering, Nathalie Jores, Whitney Kilu, Espen Schallmayer, Evelyn Peelen, Andreas Muehler, Hella Kohlhof, Daniel Vitt, Verena Linhard, Santosh L Gande, Apirat Chaikuad, Sridhar Sreeramulu, Harald Schwalbe, Daniel Merk
Mechanistic Impact of Different Ligand Scaffolds on FXR Modulation Suggests Avenues to Selective Modulators. ACS chemical biology 17 (11) (2022)
Markus Hartmann, Jessica Huber, Jan S Kramer, Jan Heering, Larissa Pietsch, Holger Stark, Dalibor Odadzic, Iris Bischoff, Robert Fürst, Martin Schröder, Masato Akutsu, Apirat Chaikuad, Volker Dötsch, Stefan Knapp, Ricardo M Biondi, Vladimir V Rogov, Ewgenij Proschak
Demonstrating Ligandability of the LC3A and LC3B Adapter Interface. Journal of medicinal chemistry 64 (7) (2021)
Felix F Lillich, Sabine Willems, Xiaomin Ni, Whitney Kilu, Carmen Borkowsky, Mirko Brodsky, Jan S Kramer, Steffen Brunst, Victor Hernandez-Olmos, Jan Heering, Simone Schierle, Roxane-I Kestner, Franziska M Mayser, Moritz Helmstädter, Tamara Göbel, Lilia Weizel, Dmitry Namgaladze, Astrid Kaiser, Dieter Steinhilber, Waltraud Pfeilschifter, Astrid S Kahnt, Anna Proschak, Apirat Chaikuad, Stefan Knapp, Daniel Merk, Ewgenij Proschak
Structure-Based Design of Dual Partial Peroxisome Proliferator-Activated Receptor γ Agonists/Soluble Epoxide Hydrolase Inhibitors. Journal of medicinal chemistry 64 (23) (2021)
Daniel Zaienne, Sabine Willems, Simone Schierle, Jan Heering, Daniel Merk
Development and Profiling of Inverse Agonist Tools for the Neuroprotective Transcription Factor Nurr1. Journal of medicinal chemistry 64 (20) (2021)
Giuseppe Faudone, Whitney Kilu, Xiaomin Ni, Apirat Chaikuad, Sridhar Sreeramulu, Pascal Heitel, Harald Schwalbe, Stefan Knapp, Manfred Schubert-Zsilavecz, Jan Heering, Daniel Merk
The Transcriptional Repressor Orphan Nuclear Receptor TLX Is Responsive to Xanthines. ACS pharmacology & translational science 4 (6) (2021)
Markus Hartmann, Sofia-Iris Bibli, Daniel Tews, Xiaomin Ni, Theresa Kircher, Jan S Kramer, Whitney Kilu, Jan Heering, Victor Hernandez-Olmos, Lilia Weizel, Gerhard K E Scriba, Sulaiman Krait, Stefan Knapp, Apirat Chaikuad, Daniel Merk, Ingrid Fleming, Pamela Fischer-Posovszky, Ewgenij Proschak
Combined Cardioprotective and Adipocyte Browning Effects Promoted by the Eutomer of Dual sEH/PPARγ Modulator. Journal of medicinal chemistry 64 (5) (2021)
Victor Hernandez-Olmos, Jan Heering, Iris Bischoff-Kont, Alexander Kaps, Rinusha Rajkumar, Ting Liu, Robert Fürst, Dieter Steinhilber, Ewgenij Proschak
Discovery of Irbesartan Derivatives as BLT2 Agonists by Virtual Screening. ACS medicinal chemistry letters 12 (8) (2021)
Giuseppe Faudone, Iris Bischoff-Kont, Lea Rachor, Sabine Willems, Rezart Zhubi, Astrid Kaiser, Apirat Chaikuad, Stefan Knapp, Robert Fürst, Jan Heering, Daniel Merk
Propranolol Activates the Orphan Nuclear Receptor TLX to Counteract Proliferation and Migration of Glioblastoma Cells. Journal of medicinal chemistry 64 (12) (2021)
Apirat Chaikuad, Julius Pollinger, Michael Rühl, Xiaomin Ni, Whitney Kilu, Jan Heering, Daniel Merk
Comprehensive Set of Tertiary Complex Structures and Palmitic Acid Binding Provide Molecular Insights into Ligand Design for RXR Isoforms. International journal of molecular sciences 21 (22) (2020)