Salvatore Spicuglia

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 20

Top Topics

Transcription Factor

Acute Lymphoblastic Leukemia

Top Venues

Journal of leukocyte biology

Genome research

BioEssays : news and reviews in molecular, cellular and developmental biology

This page only lists publications with an associated author ORCID identifier.

Publications

Linda Aimara Kempis-Calanis, Otoniel Rodríguez-Jorge, Darely Yarazeth Gutiérrez-Reyna, Carlos Jesús Ventura-Martínez, Salvatore Spicuglia, Alejandra Medina-Rivera, Denis Thieffry, Aitor González, María Angélica Santana
Neonatal CD4+ T cells have a characteristic transcriptome and epigenome and respond to TCR stimulation with proliferation and yet a limited immune response. Journal of leukocyte biology 116 (1) (2024)
Linda Aimara Kempis-Calanis, Otoniel Rodríguez-Jorge, Darely Yarazeth Gutiérrez-Reyna, Carlos Jesús Ventura-Martínez, Salvatore Spicuglia, Alejandra Medina-Rivera, Denis Thieffry, Aitor González, María Angélica Santana
Neonatal CD4+ T cells have a characteristic transcriptome and epigenome and respond to TCR stimulation with proliferation and yet a limited immune response. Journal of leukocyte biology 116 (1) (2024)
Saadat Hussain, Nori Sadouni, Dominic van Essen, Lan T M Dao, Quentin Ferré, Guillaume Charbonnier, Magali Torres, Frederic Gallardo, Charles-Henri Lecellier, Tom Sexton, Simona Saccani, Salvatore Spicuglia
Short tandem repeats are important contributors to silencer elements in T cells. Nucleic acids research (2023)
Cyril Esnault, Talha Magat, Amal Zine El Aabidine, Encar Garcia-Oliver, Anne Cucchiarini, Soumya Bouchouika, David Lleres, Lutz Goerke, Yu Luo, Daniela Verga, Laurent Lacroix, Robert Feil, Salvatore Spicuglia, Jean-Louis Mergny, Jean-Christophe Andrau
G4access identifies G-quadruplexes and their associations with open chromatin and imprinting control regions. Nature genetics (2023)
Lucien Courtois, Aurelie Cabannes-Hamy, Rathana Kim, Marine Delecourt, Antoine Pinton, Guillaume Charbonnier, Mélanie Féroul, Charlotte L Smith, Giulia Tueur, Cecile Pivert, Estelle Balducci, Mathieu Simonin, Laure Hélène Angel, Salvatore Spicuglia, Nicolas Boissel, Guillaume P Andrieu, Vahid Asnafi, Philippe Rousselot, Ludovic Lhermitte
IL7-receptor expression is frequent in T-cell acute lymphoblastic leukemia and predicts sensitivity to JAK-inhibition. Blood (2023)
Salvatore Spicuglia, Álvaro Rada-Iglesias
Understanding enhancer function to understand human disease. BioEssays : news and reviews in molecular, cellular and developmental biology (2023)
Linda Aimara Kempis-Calanis, Otoniel Rodríguez-Jorge, Darely Yarazeth Gutiérrez-Reyna, Carlos Jesús Ventura-Martínez, Salvatore Spicuglia, Alejandra Medina-Rivera, Denis Thieffry, Aimara González, María Angélica Santana
Neonatal CD4+T cells have a characteristic transcriptome and epigenome and respond to TCR stimulation with proliferation and yet a limited immune response. Journal of leukocyte biology (2023)
Antoine Pinton, Lucien Courtois, Charlotte Doublet, Aurélie Cabannes-Hamy, Guillaume P Andrieu, Charlotte L Smith, Estelle Balducci, Agata Cieslak, Aurore Touzart, Mathieu Simonin, Véronique Lhéritier, Françoise Huguet, Marie Balsat, Hervé Dombret, Philippe Rousselot, Salvatore Spicuglia, Elizabeth A Macintyre, Nicolas Boissel, Vahid Asnafi
PHF6-altered T-ALL harbor epigenetic repressive switch at bivalent promoters and respond to 5-azacitidine and venetoclax. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Juliette Malfait, Jing Wan, Salvatore Spicuglia
Epromoters are new players in the regulatory landscape with potential pleiotropic roles. BioEssays : news and reviews in molecular, cellular and developmental biology (2023)
Judith Barbara Zaugg, Pelin Sahlén, Robin Andersson, Meritxell Alberich-Jorda, Wouter de Laat, Bart Deplancke, Jorge Ferrer, Susanne Mandrup, Gioacchino Natoli, Dariusz Plewczyński, Álvaro Rada-Iglesias, Salvatore Spicuglia
Current challenges in understanding the role of enhancers in disease. Nature structural & molecular biology (2022)
Mohamed Belhocine, Mathieu Simonin, José David Abad Flores, Agata Cieslak, Iris Manosalva, Lydie Pradel, Charlotte Smith, Eve-Lyne Mathieu, Guillaume Charbonnier, Joost H A Martens, Hendrik G Stunnenberg, Muhammad Ahmad Maqbool, Aneta Mikulasova, Lisa J Russell, Daniel Rico, Denis Puthier, Pierre Ferrier, Vahid Asnafi, Salvatore Spicuglia
Dynamic of broad H3K4me3 domains uncover an epigenetic switch between cell identity and cancer-related genes. Genome research (2021)
David Santiago-Algarra, Charbel Souaid, Himanshu Narayan Singh, Lan T M Dao, Saadat Hussain, Alejandra Medina-Rivera, Lucia Ramirez-Navarro, Jaime A Castro-Mondragon, Nori Sadouni, Guillaume Charbonnier, Salvatore Spicuglia
Epromoters function as a hub to recruit key transcription factors required for the inflammatory response. Nature communications 12 (1) (2021)
Guillaume P Andrieu, Milena Kohn, Mathieu Simonin, Charlotte L Smith, Agata Cieslak, Marie-Émilie Dourthe, Guillaume Charbonnier, Carlos Graux, Françoise Huguet, Véronique Lhéritier, Hervé Dombret, Salvatore Spicuglia, Philippe Rousselot, Nicolas Boissel, Vahid Asnafi
PRC2 loss of function confers a targetable vulnerability to BET proteins in T-ALL. Blood 138 (19) (2021)
Aneta Mikulasova, Daniel Kent, Marco Trevisan-Herraz, Nefeli Karataraki, Kent T M Fung, Timothy Cody Ashby, Agata Cieslak, Shmuel Yaccoby, Frits van Rhee, Maurizio Zangari, Sharmilan Thanendrarajan, Carolina Schinke, Gareth J Morgan, Vahid Asnafi, Salvatore Spicuglia, Chris A Brackley, Anne E Corcoran, Sophie Hambleton, Brian A Walker, Daniel Rico, Lisa J Russell
Epigenomic translocation of H3K4me3 broad domains over oncogenes following hijacking of super-enhancers. Genome research 32 (7) (2021)
Aurore Touzart, Anand Mayakonda, Charlotte L Smith, Joschka Hey, Reka Toth, Agata Cieslak, Guillaume P Andrieu, Christine Tran Quang, Mehdi Latiri, Jacques Ghysdael, Salvatore Spicuglia, Hervé Dombret, Norbert Ifrah, Elizabeth A Macintyre, Pavlo Lutsik, Nicolas Boissel, Christoph Plass, Vahid Asnafi
Epigenetic analysis of patients with T-ALL identifies poor outcomes and a hypomethylating agent-responsive subgroup. Science translational medicine 13 (595) (2021)
Jaafar Alomairi, Anne M Molitor, Nori Sadouni, Saadat Hussain, Magali Torres, Wiam Saadi, Lan T M Dao, Guillaume Charbonnier, David Santiago-Algarra, Jean Christophe Andrau, Denis Puthier, Tom Sexton, Salvatore Spicuglia
Integration of high-throughput reporter assays identify a critical enhancer of the Ikzf1 gene. PloS one 15 (5) (2020)
Wiam Saadi, Yasmina Kermezli, Lan T M Dao, Evelyne Mathieu, David Santiago-Algarra, Iris Manosalva, Magali Torres, Mohamed Belhocine, Lydie Pradel, Beatrice Loriod, Eve-Lyne Mathieu, Denis Puthier, Salvatore Spicuglia
A critical regulator of Bcl2 revealed by systematic transcript discovery of lncRNAs associated with T-cell differentiation. Scientific reports 9 (1) (2019)
Yasmina Kermezli, Vahid Asnafi, Mohamed Belhocine, Eve-Lyne Mathieu, Marc-Antoine Garibal, Salvatore Spicuglia, Denis Puthier
A comprehensive catalog of LncRNAs expressed in T-cell acute lymphoblastic leukemia. Leukemia & lymphoma 60 (8) (2019)
Lan T M Dao, Salvatore Spicuglia
Transcriptional regulation by promoters with enhancer function. Transcription 9 (5) (2018)
David Santiago-Algarra, Lan T M Dao, Lydie Pradel, Alexandre España, Salvatore Spicuglia
Recent advances in high-throughput approaches to dissect enhancer function. F1000Research 6 (2017)