Jean-Louis Mergny (Jean Louis Mergny)

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 49

Top Venues

Nucleic acids research

Journal of the American Chemical Society

Scientific reports

Nature communications

Institut Curie Centre de Recherche Orsay

University Pierre et Marie Curie (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Institut Curie Centre de Recherche Orsay May 1o 2019

France

P.I.

Education History

University Pierre et Marie Curie Sep 1o 1989 - Dec 19o 1991

France

PHD

Publications

Cyril Esnault, Talha Magat, Amal Zine El Aabidine, Encar Garcia-Oliver, Anne Cucchiarini, Soumya Bouchouika, David Lleres, Lutz Goerke, Yu Luo, Daniela Verga, Laurent Lacroix, Robert Feil, Salvatore Spicuglia, Jean-Louis Mergny, Jean-Christophe Andrau
G4access identifies G-quadruplexes and their associations with open chromatin and imprinting control regions. Nature genetics (2023)
Xuanxiang Mao, Xiaobo Zhang, Zhicong Chao, Dehui Qiu, Shijiong Wei, Rengan Luo, Desheng Chen, Yue Zhang, Yun Chen, Yuanjiao Yang, David Monchaud, Huangxian Ju, Jean-Louis Mergny, Jianping Lei, Jun Zhou
A Versatile G-quadruplex (G4)-coated Upconverted Metal-Organic Framework for Hypoxic Tumor Therapy. Advanced healthcare materials (2023)
Rongxin Zhang, Huiling Shu, Yuqi Wang, Tiantong Tao, Jing Tu, Cheng Wang, Jean-Louis Mergny, Xiao Sun
G-quadruplex structures are key modulators of somatic structural variants in cancers. Cancer research (2023)
Václav Brázda, Michaela Dobrovolná, Natália Bohálová, Jean-Louis Mergny
G-quadruplexes in the evolution of hepatitis B virus. Nucleic acids research (2023)
Xiaobo Zhang, Dehui Qiu, Jielin Chen, Yue Zhang, Jiawei Wang, Desheng Chen, Yuan Liu, Mingpan Cheng, David Monchaud, Jean-Louis Mergny, Huangxian Ju, Jun Zhou
Chimeric Biocatalyst Combining Peptidic and Nucleic Acid Components Overcomes the Performance and Limitations of the Native Horseradish Peroxidase. Journal of the American Chemical Society 145 (8) (2023)
Yu Luo, Martina Lenarčič Živković, Jiawei Wang, Jan Ryneš, Silvie Foldynová-Trantírková, Lukas Trantirek, Daniela Verga, Jean-Louis Mergny
A sodium/potassium switch for G4-prone G/C-rich sequences. Nucleic acids research (2023)
Petra Školáková, Martin Gajarský, Jan Palacký, Denis Šubert, Daniel Renčiuk, Lukas Trantirek, Jean-Louis Mergny, Michaela Vorlíčková
DNA i-motif formation at neutral pH is driven by kinetic partitioning. Nucleic acids research (2023)
Xiaobo Zhang, Dehui Qiu, Jielin Chen, Yue Zhang, Jiawei Wang, Desheng Chen, Yuan Liu, Mingpan Cheng, David Monchaud, Jean-Louis Mergny, Huangxian Ju, Jun Zhou
Chimeric Biocatalyst Combining Peptidic and Nucleic Acid Components Overcomes the Performance and Limitations of the Native Horseradish Peroxidase. Journal of the American Chemical Society 145 (8) (2023)
Xiaobo Zhang, Dehui Qiu, Jielin Chen, Yue Zhang, Jiawei Wang, Desheng Chen, Yuan Liu, Mingpan Cheng, David Monchaud, Jean-Louis Mergny, Huangxian Ju, Jun Zhou
Chimeric Biocatalyst Combining Peptidic and Nucleic Acid Components Overcomes the Performance and Limitations of the Native Horseradish Peroxidase. Journal of the American Chemical Society (2023)
Lucille Ferret, Karla Alvarez-Valadez, Jennifer Rivière, Alexandra Muller, Natalia Bohálová, Luo Yu, Lionel Guittat, Václav Brázda, Guido Kroemer, Jean-Louis Mergny, Mojgan Djavaheri-Mergny
G-quadruplex ligands as potent regulators of lysosomes. Autophagy (2023)
Julien Marquevielle, Aurore De Rache, Brune Vialet, Estelle Morvan, Jean-Louis Mergny, Samir Amrane
G-quadruplex structure of the C. elegans telomeric repeat: a two tetrads basket type conformation stabilized by a non-canonical C-T base-pair. Nucleic acids research 50 (12) (2022)
Julien Marquevielle, Aurore De Rache, Brune Vialet, Estelle Morvan, Jean-Louis Mergny, Samir Amrane
G-quadruplex structure of the C. elegans telomeric repeat: a two tetrads basket type conformation stabilized by a non-canonical C-T base-pair. Nucleic acids research 50 (12) (2022)
Samir Amrane, Chloé Jaubert, Amina Bedrat, Tiffany Rundstadler, Patricia Recordon-Pinson, Cindy Aknin, Aurore Guédin, Aurore De Rache, Laura Bartolucci, Ibra Diene, Frederic Lemoine, Olivier Gascuel, Geneviève Pratviel, Jean-Louis Mergny, Marie-Line Andreola
Deciphering RNA G-quadruplex function during the early steps of HIV-1 infection. Nucleic acids research (2022)
André Miranda, Roi Lopez-Blanco, Jéssica Lopes-Nunes, Ana M Melo, Maria Paula Cabral Campello, António Paulo, Maria Cristina Oliveira, Jean-Louis Mergny, Paula Alexandra Oliveira, Eduardo Fernandez-Megia, Carla Cruz
Gallic Acid-Triethylene Glycol Aptadendrimers Synthesis, Biophysical Characterization and Cellular Evaluation. Pharmaceutics 14 (11) (2022)
Julien Marquevielle, Aurore De Rache, Brune Vialet, Estelle Morvan, Jean-Louis Mergny, Samir Amrane
G-quadruplex structure of the C. elegans telomeric repeat: a two tetrads basket type conformation stabilized by a non-canonical C-T base-pair. Nucleic acids research 50 (12) (2022)
Yu Luo, Daniela Verga, Jean-Louis Mergny
Iso-FRET: an isothermal competition assay to analyze quadruplex formation in vitro. Nucleic acids research 50 (16) (2022)
Jean Guillon, Anita Cohen, Clotilde Boudot, Sarah Monic, Solène Savrimoutou, Stéphane Moreau, Sandra Albenque-Rubio, Camille Lafon-Schmaltz, Alexandra Dassonville-Klimpt, Jean-Louis Mergny, Luisa Ronga, Mikel Bernabeu de Maria, Jeremy Lamarche, Cristina Dal Lago, Eric Largy, Valerie Gabelica, Serge Moukha, Pascale Dozolme, Patrice Agnamey, Nadine Azas, Catherine Mullié, Bertrand Courtioux, Pascal Sonnet
Design, Synthesis, and Antiprotozoal Evaluation of New Promising 2,9- Bis [(substituted-aminomethyl)]-4,7-phenyl-1,10-phenanthroline Derivatives, a Potential Alternative Scaffold to Drug Efflux. Pathogens (Basel, Switzerland) 11 (11) (2022)
Alessio Cantara, Yu Luo, Michaela Dobrovolná, Natalia Bohalova, Miroslav Fojta, Daniela Verga, Lionel Guittat, Anne Cucchiarini, Solène Savrimoutou, Cécile Häberli, Jean Guillon, Jennifer Keiser, Václav Brázda, Jean-Louis Mergny
G-quadruplexes in helminth parasites. Nucleic acids research 50 (5) (2022)
Julien Marquevielle, Aurore De Rache, Brune Vialet, Estelle Morvan, Jean-Louis Mergny, Samir Amrane
G-quadruplex structure of the C. elegans telomeric repeat: a two tetrads basket type conformation stabilized by a non-canonical C-T base-pair. Nucleic acids research 50 (12) (2022)
Michaela Dobrovolná, Natália Bohálová, Vratislav Peska, Jiawei Wang, Yu Luo, Martin Bartas, Adriana Volná, Jean-Louis Mergny, Václav Brázda
The Newly Sequenced Genome of Pisum sativum Is Replete with Potential G-Quadruplex-Forming Sequences-Implications for Evolution and Biological Regulation. International journal of molecular sciences 23 (15) (2022)
Mingpan Cheng, Jielin Chen, Huangxian Ju, Jun Zhou, Jean-Louis Mergny
Drivers of i-DNA Formation in a Variety of Environments Revealed by Four-Dimensional UV Melting and Annealing. Journal of the American Chemical Society 143 (20) (2021)
Mingpan Cheng, Dehui Qiu, Liezel Tamon, Eva Ištvánková, Pavlína Víšková, Samir Amrane, Aurore Guédin, Jielin Chen, Laurent Lacroix, Huangxian Ju, Lukas Trantirek, Aleksandr B Sahakyan, Jun Zhou, Jean-Louis Mergny
Thermal and pH Stabilities of i-DNA: Confronting in vitro Experiments with Models and In-Cell NMR Data. Angewandte Chemie (International ed. in English) 60 (18) (2021)
Mikayel Aznauryan, Sofie Louise Noer, Camilla W Pedersen, Jean-Louis Mergny, Marie-Paule Teulade-Fichou, Victoria Birkedal
Ligand Binding to Dynamically Populated G-Quadruplex DNA. Chembiochem : a European journal of chemical biology 22 (10) (2021)
Petr Stadlbauer, Barira Islam, Michal Otyepka, Jielin Chen, David Monchaud, Jun Zhou, Jean-Louis Mergny, Jiřı Šponer
Insights into G-Quadruplex-Hemin Dynamics Using Atomistic Simulations: Implications for Reactivity and Folding. Journal of chemical theory and computation 17 (3) (2021)
Ardavan Abiri, Marc Lavigne, Masoud Rezaei, Sanaz Nikzad, Peyman Zare, Jean-Louis Mergny, Hamid Reza Rahimi
Unlocking G-Quadruplexes as Antiviral Targets. Pharmacological reviews 73 (3) (2021)
Jielin Chen, Mingpan Cheng, Gilmar F Salgado, Petr Stadlbauer, Xiaobo Zhang, Samir Amrane, Aurore Guédin, Fangni He, Jiří Šponer, Huangxian Ju, Jean-Louis Mergny, Jun Zhou
The beginning and the end: flanking nucleotides induce a parallel G-quadruplex topology. Nucleic acids research 49 (16) (2021)
Marc Lavigne, Olivier Helynck, Pascal Rigolet, Rofia Boudria-Souilah, Mireille Nowakowski, Bruno Baron, Sébastien Brülé, Sylviane Hoos, Bertrand Raynal, Lionel Guittat, Claire Beauvineau, Stéphane Petres, Anton Granzhan, Jean Guillon, Geneviève Pratviel, Marie-Paule Teulade-Fichou, Patrick England, Jean-Louis Mergny, Hélène Munier-Lehmann
SARS-CoV-2 Nsp3 unique domain SUD interacts with guanine quadruplexes and G4-ligands inhibit this interaction. Nucleic acids research 49 (13) (2021)
Annalisa Ferino, Julien Marquevielle, Himanshi Choudhary, Giorgio Cinque, Coralie Robert, Anne Bourdoncle, Raffaella Picco, Jean-Louis Mergny, Gilmar F Salgado, Luigi E Xodo
hnRNPA1/UP1 Unfolds KRAS G-Quadruplexes and Feeds a Regulatory Axis Controlling Gene Expression. ACS omega 6 (49) (2021)
Nunzia Iaccarino, Mingpan Cheng, Dehui Qiu, Bruno Pagano, Jussara Amato, Anna Di Porzio, Jun Zhou, Antonio Randazzo, Jean-Louis Mergny
Effects of Sequence and Base Composition on the CD and TDS Profiles of i-DNA. Angewandte Chemie (International ed. in English) 60 (18) (2021)
Jiawei Wang, Mingpan Cheng, Jielin Chen, Huangxian Ju, David Monchaud, Jean-Louis Mergny, Jun Zhou
An oxidatively damaged G-quadruplex/hemin DNAzyme. Chemical communications (Cambridge, England) 56 (12) (2020)
Yu Luo, Anton Granzhan, Daniela Verga, Jean-Louis Mergny
FRET-MC: A fluorescence melting competition assay for studying G4 structures in vitro. Biopolymers 112 (4) (2020)
Jennifer Beauvarlet, Rabindra Nath Das, Karla Alvarez-Valadez, Isabelle Martins, Alexandra Muller, Elodie Darbo, Elodie Richard, Pierre Soubeyran, Guido Kroemer, Jean Guillon, Jean-Louis Mergny, Mojgan Djavaheri-Mergny
Triarylpyridine Compounds and Chloroquine Act in Concert to Trigger Lysosomal Membrane Permeabilization and Cell Death in Cancer Cells. Cancers 12 (6) (2020)
Barira Islam, Petr Stadlbauer, Michaela Vorlíčková, Jean-Louis Mergny, Michal Otyepka, Jiřı Šponer
Stability of Two-Quartet G-Quadruplexes and Their Dimers in Atomistic Simulations. Journal of chemical theory and computation 16 (6) (2020)
Paulina Prorok, Marie Artufel, Antoine Aze, Philippe Coulombe, Isabelle Peiffer, Laurent Lacroix, Aurore Guédin, Jean-Louis Mergny, Julia Damaschke, Aloys Schepers, Christelle Cayrou, Marie-Paule Teulade-Fichou, Benoit Ballester, Marcel Méchali
Author Correction: Involvement of G-quadruplex regions in mammalian replication origin activity. Nature communications 11 (1) (2020)
Václav Brázda, Yu Luo, Martin Bartas, Patrik Kaura, Otilia Porubiaková, Jiří Šťastný, Petr Pečinka, Daniela Verga, Violette Da Cunha, Tomio S Takahashi, Patrick Forterre, Hannu Myllykallio, Miroslav Fojta, Jean-Louis Mergny
G-Quadruplexes in the Archaea Domain. Biomolecules 10 (9) (2020)
Jean-Louis Mergny, Dipankar Sen
Correction to DNA Quadruple Helices in Nanotechnology. Chemical reviews 120 (20) (2020)
Michaela Krafcikova, Simon Dzatko, Coralie Caron, Anton Granzhan, Radovan Fiala, Tomas Loja, Marie-Paule Teulade-Fichou, Tomas Fessl, Robert Hänsel-Hertsch, Jean-Louis Mergny, Silvie Foldynova-Trantirkova, Lukas Trantirek
Monitoring DNA-Ligand Interactions in Living Human Cells Using NMR Spectroscopy. Journal of the American Chemical Society 141 (34) (2019)
Priyanka Toshniwal, Michelle Nguyen, Aurore Guédin, Helena Viola, Diwei Ho, Yongeun Kim, Uditi Bhatt, Charles S Bond, Livia Hool, Laurence H Hurley, Jean-Louis Mergny, Mark Fear, Fiona Wood, Swaminathan K Iyer, Nicole M Smith
TGF-β-induced fibrotic stress increases G-quadruplex formation in human fibroblasts. FEBS letters 593 (22) (2019)
Caterina Maria Lombardo, Vasantha Kumar M V, Céline Douat, Frédéric Rosu, Jean-Louis Mergny, Gilmar F Salgado, Gilles Guichard
Design and Structure Determination of a Composite Zinc Finger Containing a Nonpeptide Foldamer Helical Domain. Journal of the American Chemical Society 141 (6) (2019)
Josué Carvalho, Artur Paiva, Maria Paula Cabral Campello, António Paulo, Jean-Louis Mergny, Gilmar F Salgado, João A Queiroz, Carla Cruz
Aptamer-based Targeted Delivery of a G-quadruplex Ligand in Cervical Cancer Cells. Scientific reports 9 (1) (2019)
Paulina Prorok, Marie Artufel, Antoine Aze, Philippe Coulombe, Isabelle Peiffer, Laurent Lacroix, Aurore Guédin, Jean-Louis Mergny, Julia Damaschke, Aloys Schepers, Christelle Cayrou, Marie-Paule Teulade-Fichou, Benoit Ballester, Marcel Méchali
Involvement of G-quadruplex regions in mammalian replication origin activity. Nature communications 10 (1) (2019)
Jean-Louis Mergny, Dipankar Sen
DNA Quadruple Helices in Nanotechnology. Chemical reviews 119 (10) (2019)
Chloé Jaubert, Amina Bedrat, Laura Bartolucci, Carmelo Di Primo, Michel Ventura, Jean-Louis Mergny, Samir Amrane, Marie-Line Andreola
Author Correction: RNA synthesis is modulated by G-quadruplex formation in Hepatitis C virus negative RNA strand. Scientific reports 9 (1) (2019)
Jennifer Beauvarlet, Jean-Louis Mergny, Mojgan Djavaheri-Mergny
Activation of the Ataxia Telangiectasia Mutated/Autophagy pathway by a G-quadruplex ligand links senescence with apoptosis. Molecular & cellular oncology 6 (4) (2019)
Chloé Jaubert, Amina Bedrat, Laura Bartolucci, Carmelo Di Primo, Michel Ventura, Jean-Louis Mergny, Samir Amrane, Marie-Line Andreola
RNA synthesis is modulated by G-quadruplex formation in Hepatitis C virus negative RNA strand. Scientific reports 8 (1) (2018)
Efres Belmonte-Reche, Marta Martínez-García, Aurore Guédin, Michela Zuffo, Matilde Arévalo-Ruiz, Filippo Doria, Jenny Campos-Salinas, Marjorie Maynadier, José Juan López-Rubio, Mauro Freccero, Jean-Louis Mergny, José María Pérez-Victoria, Juan Carlos Morales
G-Quadruplex Identification in the Genome of Protozoan Parasites Points to Naphthalene Diimide Ligands as New Antiparasitic Agents. Journal of medicinal chemistry 61 (3) (2018)
Nassima Meriem Gueddouda, Miyanou Rosales Hurtado, Stéphane Moreau, Luisa Ronga, Rabindra Nath Das, Solène Savrimoutou, Sandra Rubio, Adrien Marchand, Oscar Mendoza, Mathieu Marchivie, Lilian Elmi, Albain Chansavang, Vanessa Desplat, Valérie Gabelica, Anne Bourdoncle, Jean-Louis Mergny, Jean Guillon
Design, Synthesis, and Evaluation of 2,9-Bis[(substituted-aminomethyl)phenyl]-1,10-phenanthroline Derivatives as G-Quadruplex Ligands. ChemMedChem 12 (2) (2017)
Jun Zhou, Samir Amrane, Frédéric Rosu, Gilmar F Salgado, Yunqiang Bian, Hisae Tateishi-Karimata, Eric Largy, Dursun Nizam Korkut, Anne Bourdoncle, Daisuke Miyoshi, Jian Zhang, Huangxian Ju, Wei Wang, Naoki Sugimoto, Valerie Gabelica, Jean-Louis Mergny
Unexpected Position-Dependent Effects of Ribose G-Quartets in G-Quadruplexes. Journal of the American Chemical Society 139 (23) (2017)
Matilde Arévalo-Ruiz, Filippo Doria, Efres Belmonte-Reche, Aurore De Rache, Jenny Campos-Salinas, Ricardo Lucas, Eva Falomir, Miguel Carda, José María Pérez-Victoria, Jean-Louis Mergny, Mauro Freccero, Juan Carlos Morales
Synthesis, Binding Properties, and Differences in Cell Uptake of G-Quadruplex Ligands Based on Carbohydrate Naphthalene Diimide Conjugates. Chemistry (Weinheim an der Bergstrasse, Germany) 23 (9) (2017)

Jean-Louis Mergny.css-eqlu8i{font-size:small;padding-left:4px;} (Jean Louis Mergny)

Publication Activity (10 Years)

Top Topics

Top Venues

Jean-Louis Mergny (Jean Louis Mergny)