Sandip B Bharate

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 33

Top Topics

Top Venues

ACS chemical neuroscience

Drug development research

Medicinal research reviews

This page only lists publications with an associated author ORCID identifier.

Publications

Ankita Sharma, Mohit Sharma, Sandip B Bharate
N-Benzyl piperidine Fragment in Drug Discovery. ChemMedChem (2024)
Venu Sharma, Ankita Sharma, Bhagyashri N Wadje, Sandip B Bharate
Benzopyrone, a privileged scaffold in drug discovery: An overview of FDA-approved drugs and clinical candidates. Medicinal research reviews 44 (5) (2024)
Venu Sharma, Ankita Sharma, Bhagyashri N Wadje, Sandip B Bharate
Benzopyrone, a privileged scaffold in drug discovery: An overview of FDA-approved drugs and clinical candidates. Medicinal research reviews (2024)
Chilakala Nagarjuna Reddy, Vijay Kumar Nuthakki, Ankita Sharma, Sumera Malik, Misbah Tabassum, Rajesh Kumar, Sushil Choudhary, Fiza Iqbal, Ziya Tufail, Dilip M Mondhe, Ajay Kumar, Sandip B Bharate
Synthesis and Biological Evaluation of Colchicine─Aryl/Alkyl Amine Hybrids as Potential Noncytotoxic Cholinesterase Inhibitors: Identification of SBN-284 as a Dual Inhibitor of Cholinesterases and NLRP3 Inflammasome. ACS chemical neuroscience (2024)
Venu Sharma, Ankita Sharma, Bhagyashri N Wadje, Sandip B Bharate
Benzopyrone, a privileged scaffold in drug discovery: An overview of FDA-approved drugs and clinical candidates. Medicinal research reviews 44 (5) (2024)
Chilakala Nagarjuna Reddy, Vijay Kumar Nuthakki, Ankita Sharma, Sumera Malik, Misbah Tabassum, Rajesh Kumar, Sushil Choudhary, Fiza Iqbal, Ziya Tufail, Dilip M Mondhe, Ajay Kumar, Sandip B Bharate
Synthesis and Biological Evaluation of Colchicine─Aryl/Alkyl Amine Hybrids as Potential Noncytotoxic Cholinesterase Inhibitors: Identification of SBN-284 as a Dual Inhibitor of Cholinesterases and NLRP3 Inflammasome. ACS chemical neuroscience 15 (15) (2024)
Vijay Kumar Nuthakki, Sushil Choudhary, Chilakala N Reddy, Shipra Bhatt, Ashiya Jamwal, Anshika Jotshi, Rinky Raghuvanshi, Ankita Sharma, Shikha Thakur, Hemant R Jadhav, Sonali S Bharate, Utpal Nandi, Ajay Kumar, Sandip B Bharate
Design, Synthesis, and Pharmacological Evaluation of Embelin-Aryl/alkyl Amine Hybrids as Orally Bioavailable Blood-Brain Barrier Permeable Multitargeted Agents with Therapeutic Potential in Alzheimer's Disease: Discovery of SB-1448. ACS chemical neuroscience (2023)
Vijay Kumar Nuthakki, Sushil Choudhary, Chilakala N Reddy, Shipra Bhatt, Ashiya Jamwal, Anshika Jotshi, Rinky Raghuvanshi, Ankita Sharma, Shikha Thakur, Hemant R Jadhav, Sonali S Bharate, Utpal Nandi, Ajay Kumar, Sandip B Bharate
Design, Synthesis, and Pharmacological Evaluation of Embelin-Aryl/alkyl Amine Hybrids as Orally Bioavailable Blood-Brain Barrier Permeable Multitargeted Agents with Therapeutic Potential in Alzheimer's Disease: Discovery of SB-1448. ACS chemical neuroscience 14 (6) (2023)
Vijay Kumar Nuthakki, Sushil Choudhary, Chilakala N Reddy, Shipra Bhatt, Ashiya Jamwal, Anshika Jotshi, Rinky Raghuvanshi, Ankita Sharma, Shikha Thakur, Hemant R Jadhav, Sonali S Bharate, Utpal Nandi, Ajay Kumar, Sandip B Bharate
Design, Synthesis, and Pharmacological Evaluation of Embelin-Aryl/alkyl Amine Hybrids as Orally Bioavailable Blood-Brain Barrier Permeable Multitargeted Agents with Therapeutic Potential in Alzheimer's Disease: Discovery of SB-1448. ACS chemical neuroscience 14 (6) (2023)
Mohd Abdullaha, Razia Banoo, Vijay Kumar Nuthakki, Mohit Sharma, Sukhleen Kaur, Shikha Thakur, Ajay Kumar, Hemant R Jadhav, Sandip B Bharate
Methoxy-naphthyl-Linked N -Benzyl Pyridinium Styryls as Dual Cholinesterase Inhibitors: Design, Synthesis, Biological Evaluation, and Structure-Activity Relationship. ACS omega 8 (20) (2023)
Sandip B Bharate, Dennis C Liotta
Call for Papers: Natural Products Driven Medicinal Chemistry. Journal of medicinal chemistry (2023)
Ankita Sharma, Sandip B Bharate
Synthesis and Biological Evaluation of Coumarin Triazoles as Dual Inhibitors of Cholinesterases and β-Secretase. ACS omega 8 (12) (2023)
Rinky Raghuvanshi, Ashiya Jamwal, Utpal Nandi, Sandip B Bharate
Multitargeted C9-substituted ester and ether derivatives of berberrubine for Alzheimer's disease: Design, synthesis, biological evaluation, metabolic stability, and pharmacokinetics. Drug development research (2022)
Mohit Sharma, Ankita Sharma, Vijay K Nuthakki, Shipra Bhatt, Utpal Nandi, Sandip B Bharate
Design, synthesis, and structure-activity relationship of caffeine-based triazoles as dual AChE and BACE-1 inhibitors. Drug development research (2022)
Deendyal Bhurta, Sandip B Bharate
Styryl Group, a Friend or Foe in Medicinal Chemistry. ChemMedChem 17 (7) (2022)
Deendyal Bhurta, Sandip B Bharate
Discovery of Pongol, the Furanoflavonoid, as an Inhibitor of CDK7/Cyclin H/MAT1 and Its Preliminary Structure-Activity Relationship. ACS omega 8 (1) (2022)
Razia Banoo, Vijay K Nuthakki, Mohd Abdullaha, Mohit Sharma, Sandip B Bharate
Blood-brain barrier permeable benzylpiperidin-4-yl-linked benzylamino benzamides as dual cholinesterase inhibitors. Drug development research (2022)
Deendyal Bhurta, Sandip B Bharate
Discovery of Pongol, the Furanoflavonoid, as an Inhibitor of CDK7/Cyclin H/MAT1 and Its Preliminary Structure-Activity Relationship. ACS omega 8 (1) (2022)
Rinky Raghuvanshi, Sandip B Bharate
Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections. Journal of medicinal chemistry (2021)
Chaitra Prabhakara, Rashmi Godbole, Parijat Sil, Sowmya Jahnavi, Shah-E-Jahan Gulzar, Thomas S van Zanten, Dhruv Sheth, Neeraja Subhash, Anchal Chandra, Akshatha Shivaraj, Patricia Panikulam, Ibrahim U, Vijay Kumar Nuthakki, Theja Parassini Puthiyapurayil, Riyaz Ahmed, Ashaq Hussain Najar, Sai Manoz Lingamallu, Snigdhadev Das, Bhagyashri Mahajan, Praveen Vemula, Sandip B Bharate, Parvinder Pal Singh, Ram A Vishwakarma, Arjun Guha, Varadharajan Sundaramurthy, Satyajit Mayor
Strategies to target SARS-CoV-2 entry and infection using dual mechanisms of inhibition by acidification inhibitors. PLoS pathogens 17 (7) (2021)
Deendyal Bhurta, Sandip B Bharate
Analyzing the scaffold diversity of cyclin-dependent kinase inhibitors and revisiting the clinical and preclinical pipeline. Medicinal research reviews (2021)
Aboli Girme, Ganesh Saste, Sandeep Pawar, Chetana Ghule, Amit Mirgal, Saurabh Patel, Anshuly Tiwari, Sautik Ghoshal, Sandip B Bharate, Sonali S Bharate, Dumbala Srinivasa Reddy, Ram A Vishwakarma, Lal Hingorani
Quantitative Determination and Characterization of a Kashmir Saffron (Crocus sativus L.)-Based Botanical Supplement Using Single-Laboratory Validation Study by HPLC-PDA with LC-MS/MS and HPTLC Investigations. ACS omega 6 (36) (2021)
Mohd Abdullaha, Mehboob Ali, Dilpreet Kour, Ramesh Mudududdla, Parul Khajuria, Ajay Kumar, Sandip B Bharate
Tetramethoxystilbene Inhibits NLRP3 Inflammasome Assembly via Blocking the Oligomerization of Apoptosis-Associated Speck-like Protein Containing Caspase Recruitment Domain: In Vitro and In Vivo Evaluation. ACS pharmacology & translational science 4 (4) (2021)
Sheena Mahajan, Nancy Slathia, Vijay K Nuthakki, Sandip B Bharate, Kamal K Kapoor
Malononitrile-activated synthesis and anti-cholinesterase activity of styrylquinoxalin-2(1 H )-ones. RSC advances 10 (27) (2020)
Mohd Abdullaha, Shabber Mohammed, Mehboob Ali, Ajay Kumar, Ram A Vishwakarma, Sandip B Bharate
Discovery of Quinazolin-4(3 H)-ones as NLRP3 Inflammasome Inhibitors: Computational Design, Metal-Free Synthesis, and in Vitro Biological Evaluation. The Journal of organic chemistry 84 (9) (2019)
Vijay K Nuthakki, Ankita Sharma, Ajay Kumar, Sandip B Bharate
Identification of embelin, a 3-undecyl-1,4-benzoquinone from Embelia ribes as a multitargeted anti-Alzheimer agent. Drug development research 80 (5) (2019)
Prashant Joshi, Vinay R Sonawane, Ibidapo S Williams, Glen J P McCann, Linda Gatchie, Rajni Sharma, Naresh Satti, Bhabatosh Chaudhuri, Sandip B Bharate
Identification of karanjin isolated from the Indian beech tree as a potent CYP1 enzyme inhibitor with cellular efficacy via screening of a natural product repository. MedChemComm 9 (2) (2018)
Sandip B Bharate, Vikas Kumar, Shreyans K Jain, Mubashir J Mintoo, Santosh K Guru, Vijay K Nuthakki, Mohit Sharma, Sonali S Bharate, Sumit G Gandhi, Dilip M Mondhe, Shashi Bhushan, Ram A Vishwakarma
Discovery and Preclinical Development of IIIM-290, an Orally Active Potent Cyclin-Dependent Kinase Inhibitor. Journal of medicinal chemistry 61 (4) (2018)
Ramesh Mudududdla, Dinesh Mohanakrishnan, Sonali S Bharate, Ram A Vishwakarma, Dinkar Sahal, Sandip B Bharate
Orally Effective Aminoalkyl 10H-Indolo[3,2-b]quinoline-11-carboxamide Kills the Malaria Parasite by Inhibiting Host Hemoglobin Uptake. ChemMedChem 13 (23) (2018)
Ibidapo S Williams, Shifali Chib, Vijay K Nuthakki, Linda Gatchie, Prashant Joshi, Niteen A Narkhede, Ram A Vishwakarma, Sandip B Bharate, Saurabh Saran, Bhabatosh Chaudhuri
Biotransformation of Chrysin to Baicalein: Selective C6-Hydroxylation of 5,7-Dihydroxyflavone Using Whole Yeast Cells Stably Expressing Human CYP1A1 Enzyme. Journal of agricultural and food chemistry 65 (34) (2017)
Yazan S Batarseh, Sonali S Bharate, Vikas Kumar, Ajay Kumar, Ram A Vishwakarma, Sandip B Bharate, Amal Kaddoumi
Crocus sativus Extract Tightens the Blood-Brain Barrier, Reduces Amyloid β Load and Related Toxicity in 5XFAD Mice. ACS chemical neuroscience 8 (8) (2017)
Prashant Joshi, Glen J P McCann, Vinay R Sonawane, Ram A Vishwakarma, Bhabatosh Chaudhuri, Sandip B Bharate
Identification of Potent and Selective CYP1A1 Inhibitors via Combined Ligand and Structure-Based Virtual Screening and Their in Vitro Validation in Sacchrosomes and Live Human Cells. Journal of chemical information and modeling 57 (6) (2017)
Rohit Sharma, Mohd Abdullaha, Sandip B Bharate
Oxidant-Controlled C-sp2/sp3-H Cross-Dehydrogenative Coupling of N-Heterocycles with Benzylamines. The Journal of organic chemistry 82 (18) (2017)