Silke Leimkühler

Ciência ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 45

Top Topics

Escherichia Coli

Top Venues

Microbiology spectrum

Molecules (Basel, Switzerland)

This page only lists publications with an associated author ORCID identifier.

Publications

Paolo Olivieri, Arkadiuz Zupok, Tugba Yildiz, Jonathan Oltmanns, Angelika Lehmann, Ewelina Sokolowska, Aleksandra Skirycz, Volker Schünemann, Silke Leimkühler
TusA influences Fe-S cluster assembly and iron homeostasis in E. coli by reducing the translation efficiency of Fur. Microbiology spectrum (2024)
Paolo Olivieri, Arkadiuz Zupok, Tugba Yildiz, Jonathan Oltmanns, Angelika Lehmann, Ewelina Sokolowska, Aleksandra Skirycz, Volker Schünemann, Silke Leimkühler
TusA influences Fe-S cluster assembly and iron homeostasis in E. coli by reducing the translation efficiency of Fur. Microbiology spectrum (2024)
Paolo Olivieri, Moritz Klabes, Jason C Crack, Angelika Lehmann, Sophie P Bennett, Nick E Le Brun, Silke Leimkühler
Binding of IscU and TusA to different but competing sites of IscS influences the activity of IscS and directs sulfur to the respective biomolecular synthesis pathway. Microbiology spectrum (2024)
Muhammad Abrar Hasnat, Arkadiusz Zupok, Michal Gorka, Chantal Iobbi-Nivol, Aleksandra Skirycz, Cécile Jourlin-Castelli, Frank Bier, Saloni Agarwal, Ehizode Irefo, Silke Leimkühler
Iron limitation indirectly reduces the Escherichia coli torCAD operon expression by a reduction of molybdenum cofactor availability. Microbiology spectrum 12 (2) (2024)
Paolo Olivieri, Moritz Klabes, Jason C Crack, Angelika Lehmann, Sophie P Bennett, Nick E Le Brun, Silke Leimkühler
Binding of IscU and TusA to different but competing sites of IscS influences the activity of IscS and directs sulfur to the respective biomolecular synthesis pathway. Microbiology spectrum (2024)
Muhammad Abrar Hasnat, Arkadiusz Zupok, Michal Gorka, Chantal Iobbi-Nivol, Aleksandra Skirycz, Cécile Jourlin-Castelli, Frank Bier, Saloni Agarwal, Ehizode Irefo, Silke Leimkühler
Iron limitation indirectly reduces the Escherichia coli torCAD operon expression by a reduction of molybdenum cofactor availability. Microbiology spectrum (2024)
Paolo Olivieri, Arkadiuz Zupok, Tugba Yildiz, Jonathan Oltmanns, Angelika Lehmann, Ewelina Sokolowska, Aleksandra Skirycz, Volker Schünemann, Silke Leimkühler
TusA influences Fe-S cluster assembly and iron homeostasis in E. coli by reducing the translation efficiency of Fur. Microbiology spectrum 12 (8) (2024)
Paolo Olivieri, Moritz Klabes, Jason C Crack, Angelika Lehmann, Sophie P Bennett, Nick E Le Brun, Silke Leimkühler
Binding of IscU and TusA to different but competing sites of IscS influences the activity of IscS and directs sulfur to the respective biomolecular synthesis pathway. Microbiology spectrum (2024)
Muhammad Abrar Hasnat, Arkadiusz Zupok, Michal Gorka, Chantal Iobbi-Nivol, Aleksandra Skirycz, Cécile Jourlin-Castelli, Frank Bier, Saloni Agarwal, Ehizode Irefo, Silke Leimkühler
Iron limitation indirectly reduces the Escherichia coli torCAD operon expression by a reduction of molybdenum cofactor availability. Microbiology spectrum 12 (2) (2024)
Muhammad Abrar Hasnat, Arkadiusz Zupok, Michal Gorka, Chantal Iobbi-Nivol, Aleksandra Skirycz, Cécile Jourlin-Castelli, Frank Bier, Saloni Agarwal, Ehizode Irefo, Silke Leimkühler
Iron limitation indirectly reduces the Escherichia coli torCAD operon expression by a reduction of molybdenum cofactor availability. Microbiology spectrum 12 (2) (2024)
Paolo Olivieri, Arkadiuz Zupok, Tugba Yildiz, Jonathan Oltmanns, Angelika Lehmann, Ewelina Sokolowska, Aleksandra Skirycz, Volker Schünemann, Silke Leimkühler
TusA influences Fe-S cluster assembly and iron homeostasis in E. coli by reducing the translation efficiency of Fur. Microbiology spectrum 12 (8) (2024)
Mariam Esmaeeli, Manfred Nimtz, Lothar Jänsch, Lloyd W Ruddock, Silke Leimkühler
Mechanistic insights into the ROS-mediated inactivation of human aldehyde oxidase. FEBS letters (2023)
Hemant Kumar, Maryam Khosraneh, Siva S M Bandaru, Carola Schulzke, Silke Leimkühler
The Mechanism of Metal-Containing Formate Dehydrogenases Revisited: The Formation of Bicarbonate as Product Intermediate Provides Evidence for an Oxygen Atom Transfer Mechanism. Molecules (Basel, Switzerland) 28 (4) (2023)
Mariam Esmaeeli, Manfred Nimtz, Lothar Jänsch, Lloyd W Ruddock, Silke Leimkühler
Inactivation of Human Aldehyde Oxidase by Small Sulfhydryl-containing Reducing Agents . Drug metabolism and disposition: the biological fate of chemicals (2023)
Moses Olalekan Ogunkola, Gaelle Guiraudie-Capraz, Francois Feron, Silke Leimkühler
The Human Mercaptopyruvate Sulfurtransferase TUM1 Is Involved in Moco Biosynthesis, Cytosolic tRNA Thiolation and Cellular Bioenergetics in Human Embryonic Kidney Cells. Biomolecules 13 (1) (2023)
Moses Olalekan Ogunkola, Gaelle Guiraudie-Capraz, Francois Feron, Silke Leimkühler
The Human Mercaptopyruvate Sulfurtransferase TUM1 Is Involved in Moco Biosynthesis, Cytosolic tRNA Thiolation and Cellular Bioenergetics in Human Embryonic Kidney Cells. Biomolecules 13 (1) (2023)
Hemant Kumar, Maryam Khosraneh, Siva S M Bandaru, Carola Schulzke, Silke Leimkühler
The Mechanism of Metal-Containing Formate Dehydrogenases Revisited: The Formation of Bicarbonate as Product Intermediate Provides Evidence for an Oxygen Atom Transfer Mechanism. Molecules (Basel, Switzerland) 28 (4) (2023)
Hemant Kumar, Maryam Khosraneh, Siva S M Bandaru, Carola Schulzke, Silke Leimkühler
The Mechanism of Metal-Containing Formate Dehydrogenases Revisited: The Formation of Bicarbonate as Product Intermediate Provides Evidence for an Oxygen Atom Transfer Mechanism. Molecules (Basel, Switzerland) 28 (4) (2023)
Hemant Kumar, Silke Leimkühler
Changing the Electron Acceptor Specificity of Rhodobacter capsulatus Formate Dehydrogenase from NAD + to NADP . International journal of molecular sciences 24 (22) (2023)
Hemant Kumar, Maryam Khosraneh, Siva S M Bandaru, Carola Schulzke, Silke Leimkühler
The Mechanism of Metal-Containing Formate Dehydrogenases Revisited: The Formation of Bicarbonate as Product Intermediate Provides Evidence for an Oxygen Atom Transfer Mechanism. Molecules (Basel, Switzerland) 28 (4) (2023)
Moses Olalekan Ogunkola, Gaelle Guiraudie-Capraz, Francois Feron, Silke Leimkühler
The Human Mercaptopyruvate Sulfurtransferase TUM1 Is Involved in Moco Biosynthesis, Cytosolic tRNA Thiolation and Cellular Bioenergetics in Human Embryonic Kidney Cells. Biomolecules 13 (1) (2023)
Hemant Kumar, Maryam Khosraneh, Siva S M Bandaru, Carola Schulzke, Silke Leimkühler
The Mechanism of Metal-Containing Formate Dehydrogenases Revisited: The Formation of Bicarbonate as Product Intermediate Provides Evidence for an Oxygen Atom Transfer Mechanism. Molecules (Basel, Switzerland) 28 (4) (2023)
Moses Olalekan Ogunkola, Gaelle Guiraudie-Capraz, Francois Feron, Silke Leimkühler
The Human Mercaptopyruvate Sulfurtransferase TUM1 Is Involved in Moco Biosynthesis, Cytosolic tRNA Thiolation and Cellular Bioenergetics in Human Embryonic Kidney Cells. Biomolecules 13 (1) (2023)
Silke Leimkühler
Metal-Containing Formate Dehydrogenases, a Personal View. Molecules (Basel, Switzerland) 28 (14) (2023)
Holly A Reeve, Jake H Nicholson, Farieha Altaf, Thomas H Lonsdale, Janina Preissler, Lars Lauterbach, Oliver Lenz, Silke Leimkühler, Frank Hollmann, Caroline E Paul, Kylie A Vincent
A hydrogen-driven biocatalytic approach to recycling synthetic analogues of NAD(P)H. Chemical communications (Cambridge, England) 58 (75) (2022)
Sven Timo Stripp, Benjamin R Duffus, Vincent Fourmond, Christophe Léger, Silke Leimkühler, Shun Hirota, Yilin Hu, Andrew J Jasniewski, Hideaki Ogata, Markus W Ribbe
Second and Outer Coordination Sphere Effects in Nitrogenase, Hydrogenase, Formate Dehydrogenase, and CO Dehydrogenase. Chemical reviews 122 (14) (2022)
Konstantin Laun, Benjamin R Duffus, Stefan Wahlefeld, Sagie Katz, Dennis Belger, Peter Hildebrandt, Maria-Andrea Mroginski, Silke Leimkühler, Ingo Zebger
Infrared Spectroscopy Elucidates the Inhibitor Binding Sites in a Metal-Dependent Formate Dehydrogenase. Chemistry (Weinheim an der Bergstrasse, Germany) 28 (54) (2022)
Kenji M Fujihara, Bonnie Z Zhang, Thomas D Jackson, Moses Olalekan Ogunkola, Brunda Nijagal, Julia V Milne, David A Sallman, Ching-Seng Ang, Iva Nikolic, Conor J Kearney, Simon J Hogg, Carlos S Cabalag, Vivien R Sutton, Sally Watt, Asuka T Fujihara, Joseph A Trapani, Kaylene J Simpson, Diana Stojanovski, Silke Leimkühler, Sue Haupt, Wayne A Phillips, Nicholas James Clemons
Eprenetapopt triggers ferroptosis, inhibits NFS1 cysteine desulfurase, and synergizes with serine and glycine dietary restriction. Science advances 8 (37) (2022)
Tugba Yildiz, Silke Leimkühler
TusA Is a Versatile Protein That Links Translation Efficiency to Cell Division in Escherichia coli. Journal of bacteriology 203 (7) (2021)
Cristiano Mota, Ana Diniz, Catarina Coelho, Teresa Santos-Silva, Mariam Esmaeeli, Silke Leimkühler, Eurico J Cabrita, Filipa Marcelo, Maria João Romão
Interrogating the Inhibition Mechanisms of Human Aldehyde Oxidase by X-ray Crystallography and NMR Spectroscopy: The Raloxifene Case. Journal of medicinal chemistry 64 (17) (2021)
Silke Leimkühler
The biosynthesis of the molybdenum cofactors in Escherichia coli. Environmental microbiology 22 (6) (2020)
Benjamin R Duffus, Peer Schrapers, Nils Schuth, Stefan Mebs, Holger Dau, Silke Leimkühler, Michael Haumann
Anion Binding and Oxidative Modification at the Molybdenum Cofactor of Formate Dehydrogenase from Rhodobacter capsulatus Studied by X-ray Absorption Spectroscopy. Inorganic chemistry 59 (1) (2019)
Olivier N Lemaire, Flora A Honoré, Sébastien Tempel, Emma M Fortier, Silke Leimkühler, Vincent Méjean, Chantal Iobbi-Nivol
Shewanella decolorationis LDS1 Chromate Resistance. Applied and environmental microbiology 85 (18) (2019)
Stefan Reschke, Benjamin R Duffus, Peer Schrapers, Stefan Mebs, Christian Teutloff, Holger Dau, Michael Haumann, Silke Leimkühler
Identification of YdhV as the First Molybdoenzyme Binding a Bis-Mo-MPT Cofactor in Escherichia coli. Biochemistry 58 (17) (2019)
Yannika Neukranz, Annika Kotter, Lena Beilschmidt, Zvonimir Marelja, Mark Helm, Ralph Gräf, Silke Leimkühler
Analysis of the Cellular Roles of MOCS3 Identifies a MOCS3-Independent Localization of NFS1 at the Tips of the Centrosome. Biochemistry 58 (13) (2019)
Nadine Schwanhold, Chantal Iobbi-Nivol, Angelika Lehmann, Silke Leimkühler
Same but different: Comparison of two system-specific molecular chaperones for the maturation of formate dehydrogenases. PloS one 13 (11) (2018)
Paul Kaufmann, Benjamin R Duffus, Biljana Mitrova, Chantal Iobbi-Nivol, Christian Teutloff, Manfred Nimtz, Lothar Jänsch, Ulla Wollenberger, Silke Leimkühler
Modulating the Molybdenum Coordination Sphere of Escherichia coli Trimethylamine N-Oxide Reductase. Biochemistry 57 (7) (2018)
Gökhan Kücükgöze, Silke Leimkühler
Direct comparison of the four aldehyde oxidase enzymes present in mouse gives insight into their substrate specificities. PloS one 13 (1) (2018)
Paul Kaufmann, Benjamin R Duffus, Christian Teutloff, Silke Leimkühler
Functional Studies on Oligotropha carboxidovorans Molybdenum-Copper CO Dehydrogenase Produced in Escherichia coli. Biochemistry 57 (19) (2018)
Martin Bühning, Martin Friemel, Silke Leimkühler
Functional Complementation Studies Reveal Different Interaction Partners of Escherichia coli IscS and Human NFS1. Biochemistry 56 (34) (2017)
Thomas Brietzke, Thomas Dietz, Alexandra Kelling, Uwe Schilde, Julianae Bois, Harald Kelm, Manuel Reh, Markus Schmitz, Thomas Körzdörfer, Silke Leimkühler, Ulla Wollenberger, Hans-Jörg Krüger, Hans-Jürgen Holdt
The 1,6,7,12-Tetraazaperylene Bridging Ligand as an Electron Reservoir and Its Disulfonato Derivative as Redox Mediator in an Enzyme-Electrode Process. Chemistry (Weinheim an der Bergstrasse, Germany) 23 (62) (2017)
Alessandro Foti, Frank Dorendorf, Silke Leimkühler
A single nucleotide polymorphism causes enhanced radical oxygen species production by human aldehyde oxidase. PloS one 12 (7) (2017)
Martin Friemel, Zvonimir Marelja, Kuanyu Li, Silke Leimkühler
The N-Terminus of Iron-Sulfur Cluster Assembly Factor ISD11 Is Crucial for Subcellular Targeting and Interaction with l-Cysteine Desulfurase NFS1. Biochemistry 56 (12) (2017)
Chao Dong, Jing Yang, Stefan Reschke, Silke Leimkühler, Martin L Kirk
Vibrational Probes of Molybdenum Cofactor-Protein Interactions in Xanthine Dehydrogenase. Inorganic chemistry 56 (12) (2017)
Martin Bühning, Angelo Valleriani, Silke Leimkühler
The Role of SufS Is Restricted to Fe-S Cluster Biosynthesis in Escherichia coli. Biochemistry 56 (14) (2017)