Thomas E Prisinzano

ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 30

Top Venues

Molecules (Basel, Switzerland)

ACS chemical neuroscience

Journal of medicinal chemistry

Organic letters

University of Kentucky

Virginia Commonwealth University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Kentucky

United States

Professor :: Pharmacy

Education History

Virginia Commonwealth University

United States

PHD :: Medicinal Chemistry

Publications

Ross van de Wetering, Amy Ewald, Susan Welsh, Lindsay Kornberger, Samuel E Williamson, Bryan D McElroy, Eduardo R Butelman, Thomas E Prisinzano, Bronwyn M Kivell
The Kappa Opioid Receptor Agonist 16-Bromo Salvinorin A Has Anti-Cocaine Effects without Significant Effects on Locomotion, Food Reward, Learning and Memory, or Anxiety and Depressive-like Behaviors. Molecules (Basel, Switzerland) 28 (12) (2023)
Joshua A Lutz, Agnieszka Sulima, Eugene S Gutman, Eric W Bow, Dan Luo, Sophia Kaska, Thomas E Prisinzano, Carol A Paronis, Jack Bergman, Gregory H Imler, Andrew T Kerr, Arthur E Jacobson, Kenner C Rice
Discovery of a Potent Highly Biased MOR Partial Agonist among Diastereomeric C9-Hydroxyalkyl-5-phenylmorphans. Molecules (Basel, Switzerland) 28 (12) (2023)
Ross van de Wetering, Amy Ewald, Susan Welsh, Lindsay Kornberger, Samuel E Williamson, Bryan D McElroy, Eduardo R Butelman, Thomas E Prisinzano, Bronwyn M Kivell
The Kappa Opioid Receptor Agonist 16-Bromo Salvinorin A Has Anti-Cocaine Effects without Significant Effects on Locomotion, Food Reward, Learning and Memory, or Anxiety and Depressive-like Behaviors. Molecules (Basel, Switzerland) 28 (12) (2023)
Ross van de Wetering, Amy Ewald, Susan Welsh, Lindsay Kornberger, Samuel E Williamson, Bryan D McElroy, Eduardo R Butelman, Thomas E Prisinzano, Bronwyn M Kivell
The Kappa Opioid Receptor Agonist 16-Bromo Salvinorin A Has Anti-Cocaine Effects without Significant Effects on Locomotion, Food Reward, Learning and Memory, or Anxiety and Depressive-like Behaviors. Molecules (Basel, Switzerland) 28 (12) (2023)
Dana R Chambers, Agnieszka Sulima, Dan Luo, Thomas E Prisinzano, Arthur E Jacobson, Kenner C Rice
A MOR Antagonist with High Potency and Antagonist Efficacy among Diastereomeric C9-Alkyl-Substituted N -Phenethyl-5-(3-hydroxy)phenylmorphans. Molecules (Basel, Switzerland) 28 (14) (2023)
Joshua A Lutz, Agnieszka Sulima, Eugene S Gutman, Eric W Bow, Dan Luo, Sophia Kaska, Thomas E Prisinzano, Carol A Paronis, Jack Bergman, Gregory H Imler, Andrew T Kerr, Arthur E Jacobson, Kenner C Rice
Discovery of a Potent Highly Biased MOR Partial Agonist among Diastereomeric C9-Hydroxyalkyl-5-phenylmorphans. Molecules (Basel, Switzerland) 28 (12) (2023)
Joshua A Lutz, Agnieszka Sulima, Eugene S Gutman, Eric W Bow, Dan Luo, Sophia Kaska, Thomas E Prisinzano, Carol A Paronis, Jack Bergman, Gregory H Imler, Andrew T Kerr, Arthur E Jacobson, Kenner C Rice
Discovery of a Potent Highly Biased MOR Partial Agonist among Diastereomeric C9-Hydroxyalkyl-5-phenylmorphans. Molecules (Basel, Switzerland) 28 (12) (2023)
Ross van de Wetering, Amy Ewald, Susan Welsh, Lindsay Kornberger, Samuel E Williamson, Bryan D McElroy, Eduardo R Butelman, Thomas E Prisinzano, Bronwyn M Kivell
The Kappa Opioid Receptor Agonist 16-Bromo Salvinorin A Has Anti-Cocaine Effects without Significant Effects on Locomotion, Food Reward, Learning and Memory, or Anxiety and Depressive-like Behaviors. Molecules (Basel, Switzerland) 28 (12) (2023)
Fuying Li, Theresa A Kopajtic, Jonathan L Katz, Dan Luo, Thomas E Prisinzano, Gregory H Imler, Jeffrey R Deschamps, Arthur E Jacobson, Kenner C Rice
Synthesis and Pharmacological Evaluation of Enantiopure N-Substituted Ortho-c Oxide-Bridged 5-Phenylmorphans. Molecules (Basel, Switzerland) 27 (24) (2022)
Fuying Li, Theresa A Kopajtic, Jonathan L Katz, Dan Luo, Thomas E Prisinzano, Gregory H Imler, Jeffrey R Deschamps, Arthur E Jacobson, Kenner C Rice
Synthesis and Pharmacological Evaluation of Enantiopure N-Substituted Ortho-c Oxide-Bridged 5-Phenylmorphans. Molecules (Basel, Switzerland) 27 (24) (2022)
Fuying Li, Theresa A Kopajtic, Jonathan L Katz, Dan Luo, Thomas E Prisinzano, Gregory H Imler, Jeffrey R Deschamps, Arthur E Jacobson, Kenner C Rice
Synthesis and Pharmacological Evaluation of Enantiopure N-Substituted Ortho-c Oxide-Bridged 5-Phenylmorphans. Molecules (Basel, Switzerland) 27 (24) (2022)
Fuying Li, Theresa A Kopajtic, Jonathan L Katz, Dan Luo, Thomas E Prisinzano, Gregory H Imler, Jeffrey R Deschamps, Arthur E Jacobson, Kenner C Rice
Synthesis and Pharmacological Evaluation of Enantiopure N-Substituted Ortho-c Oxide-Bridged 5-Phenylmorphans. Molecules (Basel, Switzerland) 27 (24) (2022)
Fuying Li, Theresa A Kopajtic, Jonathan L Katz, Dan Luo, Thomas E Prisinzano, Gregory H Imler, Jeffrey R Deschamps, Arthur E Jacobson, Kenner C Rice
Synthesis and Pharmacological Evaluation of Enantiopure N-Substituted Ortho-c Oxide-Bridged 5-Phenylmorphans. Molecules (Basel, Switzerland) 27 (24) (2022)
Dana R Chambers, Agnieszka Sulima, Dan Luo, Thomas E Prisinzano, Alexander Goldberg, Bing Xie, Lei Shi, Carol A Paronis, Jack Bergman, Nima Nassehi, Dana E Selley, Gregory H Imler, Arthur E Jacobson, Kenner C Rice
A Journey through Diastereomeric Space: The Design, Synthesis, In Vitro and In Vivo Pharmacological Activity, and Molecular Modeling of Novel Potent Diastereomeric MOR Agonists and Antagonists. Molecules (Basel, Switzerland) 27 (19) (2022)
Fuying Li, Theresa A Kopajtic, Jonathan L Katz, Dan Luo, Thomas E Prisinzano, Gregory H Imler, Jeffrey R Deschamps, Arthur E Jacobson, Kenner C Rice
Synthesis and Pharmacological Evaluation of Enantiopure N-Substituted Ortho-c Oxide-Bridged 5-Phenylmorphans. Molecules (Basel, Switzerland) 27 (24) (2022)
Sidnee L Hedrick, Dan Luo, Sophia Kaska, Kumar Kulldeep Niloy, Karen Jackson, Rupam Sarma, Jamie Horn, Caroline Baynard, Markos Leggas, Eduardo R Butelman, Mary Jeanne Kreek, Thomas E Prisinzano
Design, synthesis, and preliminary evaluation of a potential synthetic opioid rescue agent. Journal of biomedical science 28 (1) (2021)
Thomas E Prisinzano, Dennis C Liotta
NeuroChat with Professor Thomas E. Prisinzaro. ACS chemical neuroscience 11 (24) (2021)
Lisa Denny, Afnan Al Abadey, Katharina Robichon, Nikki Templeton, Thomas E Prisinzano, Bronwyn M Kivell, Anne Camille La Flamme
Nalfurafine reduces neuroinflammation and drives remyelination in models of CNS demyelinating disease. Clinical & translational immunology 10 (1) (2021)
Eduardo Roque Butelman, Caroline Baynard, Bryan D McElroy, Thomas E Prisinzano, Mary Jeanne Kreek
Profile of a short-acting κ-antagonist, LY2795050, on self-grooming behaviors, forced swim test and locomotor activity: sex comparison in mice. Journal of psychopharmacology (Oxford, England) 35 (5) (2021)
Eugene S Gutman, Eric Bow, Fuying Li, Agnieszka Sulima, Sophia Kaska, Rachel Crowley, Thomas E Prisinzano, Yong-Sok Lee, Sergio A Hassan, Gregory H Imler, Jeffrey R Deschamps, Arthur E Jacobson, Kenner C Rice
G-Protein biased opioid agonists: 3-hydroxy-N-phenethyl-5-phenylmorphans with three-carbon chain substituents at C9. RSC medicinal chemistry 11 (8) (2020)
Rachel S Crowley, Andrew P Riley, Amy F Alder, Richard J Anderson, Dan Luo, Sophia Kaska, Pamela Maynez, Bronwyn M Kivell, Thomas E Prisinzano
Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Design, Synthesis, and Evaluation of Analogues with Improved Potency and G-protein Activation Bias at the μ-Opioid Receptor. ACS chemical neuroscience 11 (12) (2020)
Bronwyn M Kivell, Kelly F Paton, Nitin Kumar, Aashish S Morani, Aimee Culverhouse, Amy Shepherd, Susan A Welsh, Andrew Biggerstaff, Rachel S Crowley, Thomas E Prisinzano
Kappa Opioid Receptor Agonist Mesyl Sal B Attenuates Behavioral Sensitization to Cocaine with Fewer Aversive Side-Effects than Salvinorin A in Rodents. Molecules (Basel, Switzerland) 23 (10) (2018)
Trey A Ronnebaum, Jeffrey S McFarlane, Thomas E Prisinzano, Squire J Booker, Audrey L Lamb
Stuffed Methyltransferase Catalyzes the Penultimate Step of Pyochelin Biosynthesis. Biochemistry 58 (6) (2018)
Alexander M Sherwood, Samuel E Williamson, Stephanie N Johnson, Anil Yilmaz, Victor W Day, Thomas E Prisinzano
Scalable Regioselective and Stereoselective Synthesis of Functionalized (E)-4-Iodobut-3-en-1-ols: Gram-Scale Total Synthesis of Fungal Decanolides and Derivatives. The Journal of organic chemistry 83 (2) (2018)
Somnath Narayan Karad, Mohan Pal, Rachel S Crowley, Thomas E Prisinzano, Ryan A Altman
Synthesis and Opioid Activity of Tyr1 -ψ[(Z)CF=CH]-Gly2 and Tyr1 -ψ[(S)/(R)-CF3 CH-NH]-Gly2 Leu-enkephalin Fluorinated Peptidomimetics. ChemMedChem 12 (8) (2017)
Kimberly M Lovell, Kevin J Frankowski, Edward L Stahl, Stephen R Slauson, Euna Yoo, Thomas E Prisinzano, Jeffrey Aubé, Laura M Bohn
Correction to "Structure-Activity Relationship Studies of Functionally Selective Kappa Opioid Receptor Agonists that Modulate ERK 1/2 Phosphorylation While Preserving G Protein Over βArrestin2 Signaling Bias". ACS chemical neuroscience 8 (7) (2017)
Anil Yilmaz, Rachel Saylor Crowley, Alexander M Sherwood, Thomas E Prisinzano
Semisynthesis and Kappa-Opioid Receptor Activity of Derivatives of Columbin, a Furanolactone Diterpene. Journal of natural products 80 (7) (2017)
Alexander M Sherwood, Rachel Saylor Crowley, Kelly F Paton, Andrew Biggerstaff, Benjamin Neuenswander, Victor W Day, Bronwyn M Kivell, Thomas E Prisinzano
Addressing Structural Flexibility at the A-Ring on Salvinorin A: Discovery of a Potent Kappa-Opioid Agonist with Enhanced Metabolic Stability. Journal of medicinal chemistry 60 (9) (2017)
Alexander M Sherwood, Samuel E Williamson, Rachel S Crowley, Logan M Abbott, Victor W Day, Thomas E Prisinzano
Modular Approach to pseudo-Neoclerodanes as Designer κ-Opioid Ligands. Organic letters 19 (19) (2017)
Rachel Saylor Crowley, Andrew P Riley, Alexander M Sherwood, Chad E Groer, Nirajmohan Shivaperumal, Miguel Biscaia, Kelly Paton, Sebastian Schneider, Davide Provasi, Bronwyn M Kivell, Marta Filizola, Thomas E Prisinzano
Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Identification of a Potent and Centrally Acting μ Opioid Analgesic with Reduced Abuse Liability. Journal of medicinal chemistry 59 (24) (2016)

Thomas E Prisinzano.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Thomas E Prisinzano