Thomas Edward Prisinzano (Thomas E Prisinzano)

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 37

Top Venues

Molecules (Basel, Switzerland)

Glia

ACS chemical neuroscience

Journal of medicinal chemistry

University of Kentucky

Virginia Commonwealth University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Kentucky

United States

Professor :: Pharmacy

University of Kansas - School of Pharmacy

United States

Associate then Professor :: Medicinal Chemistry

University of Iowa College of Pharmacy

United States

Assistant then Associate Professor :: Medicinal & Natural Products Chemistry

Education History

Virginia Commonwealth University

United States

PHD :: Medicinal Chemistry

University of Delaware

United States

BSC :: Chemistry

Publications

Hudson G Roth, Madhurima Das, Agnieszka Sulima, Dan Luo, Sophia Kaska, Thomas Edward Prisinzano, Andrew T Kerr, Arthur E Jacobson, Kenner C Rice
Functional Activity of Enantiomeric Oximes and Diastereomeric Amines and Cyano Substituents at C9 in 3-Hydroxy- N -phenethyl-5-phenylmorphans. Molecules (Basel, Switzerland) 29 (9) (2024)
Ross van de Wetering, Rabia Bibi, Andy Biggerstaff, Sheein Hong, Bria Pengelly, Thomas Edward Prisinzano, Anne Camille La Flamme, Bronwyn M Kivell
Nalfurafine promotes myelination in vitro and facilitates recovery from cuprizone + rapamycin-induced demyelination in mice. Glia (2024)
Hudson G Roth, Madhurima Das, Agnieszka Sulima, Dan Luo, Sophia Kaska, Thomas Edward Prisinzano, Andrew T Kerr, Arthur E Jacobson, Kenner C Rice
Functional Activity of Enantiomeric Oximes and Diastereomeric Amines and Cyano Substituents at C9 in 3-Hydroxy- N -phenethyl-5-phenylmorphans. Molecules (Basel, Switzerland) 29 (9) (2024)
Ross van de Wetering, Rabia Bibi, Andy Biggerstaff, Sheein Hong, Bria Pengelly, Thomas Edward Prisinzano, Anne Camille La Flamme, Bronwyn M Kivell
Nalfurafine promotes myelination in vitro and facilitates recovery from cuprizone + rapamycin-induced demyelination in mice. Glia (2024)
Ross van de Wetering, Rabia Bibi, Andy Biggerstaff, Sheein Hong, Bria Pengelly, Thomas Edward Prisinzano, Anne Camille La Flamme, Bronwyn M Kivell
Nalfurafine promotes myelination in vitro and facilitates recovery from cuprizone + rapamycin-induced demyelination in mice. Glia 72 (10) (2024)
Ross van de Wetering, Rabia Bibi, Andy Biggerstaff, Sheein Hong, Bria Pengelly, Thomas Edward Prisinzano, Anne Camille La Flamme, Bronwyn M Kivell
Nalfurafine promotes myelination in vitro and facilitates recovery from cuprizone + rapamycin-induced demyelination in mice. Glia 72 (10) (2024)
Ross van de Wetering, Amy Ewald, Susan Welsh, Lindsay Kornberger, Samuel E Williamson, Bryan D McElroy, Eduardo R Butelman, Thomas Edward Prisinzano, Bronwyn M Kivell
The Kappa Opioid Receptor Agonist 16-Bromo Salvinorin A Has Anti-Cocaine Effects without Significant Effects on Locomotion, Food Reward, Learning and Memory, or Anxiety and Depressive-like Behaviors. Molecules (Basel, Switzerland) 28 (12) (2023)
Joshua A Lutz, Agnieszka Sulima, Eugene S Gutman, Eric W Bow, Dan Luo, Sophia Kaska, Thomas Edward Prisinzano, Carol A Paronis, Jack Bergman, Gregory H Imler, Andrew T Kerr, Arthur E Jacobson, Kenner C Rice
Discovery of a Potent Highly Biased MOR Partial Agonist among Diastereomeric C9-Hydroxyalkyl-5-phenylmorphans. Molecules (Basel, Switzerland) 28 (12) (2023)
Ross van de Wetering, Amy Ewald, Susan Welsh, Lindsay Kornberger, Samuel E Williamson, Bryan D McElroy, Eduardo R Butelman, Thomas Edward Prisinzano, Bronwyn M Kivell
The Kappa Opioid Receptor Agonist 16-Bromo Salvinorin A Has Anti-Cocaine Effects without Significant Effects on Locomotion, Food Reward, Learning and Memory, or Anxiety and Depressive-like Behaviors. Molecules (Basel, Switzerland) 28 (12) (2023)
Ross van de Wetering, Amy Ewald, Susan Welsh, Lindsay Kornberger, Samuel E Williamson, Bryan D McElroy, Eduardo R Butelman, Thomas Edward Prisinzano, Bronwyn M Kivell
The Kappa Opioid Receptor Agonist 16-Bromo Salvinorin A Has Anti-Cocaine Effects without Significant Effects on Locomotion, Food Reward, Learning and Memory, or Anxiety and Depressive-like Behaviors. Molecules (Basel, Switzerland) 28 (12) (2023)
Dana R Chambers, Agnieszka Sulima, Dan Luo, Thomas Edward Prisinzano, Arthur E Jacobson, Kenner C Rice
A MOR Antagonist with High Potency and Antagonist Efficacy among Diastereomeric C9-Alkyl-Substituted N -Phenethyl-5-(3-hydroxy)phenylmorphans. Molecules (Basel, Switzerland) 28 (14) (2023)
Joshua A Lutz, Agnieszka Sulima, Eugene S Gutman, Eric W Bow, Dan Luo, Sophia Kaska, Thomas Edward Prisinzano, Carol A Paronis, Jack Bergman, Gregory H Imler, Andrew T Kerr, Arthur E Jacobson, Kenner C Rice
Discovery of a Potent Highly Biased MOR Partial Agonist among Diastereomeric C9-Hydroxyalkyl-5-phenylmorphans. Molecules (Basel, Switzerland) 28 (12) (2023)
Joshua A Lutz, Agnieszka Sulima, Eugene S Gutman, Eric W Bow, Dan Luo, Sophia Kaska, Thomas Edward Prisinzano, Carol A Paronis, Jack Bergman, Gregory H Imler, Andrew T Kerr, Arthur E Jacobson, Kenner C Rice
Discovery of a Potent Highly Biased MOR Partial Agonist among Diastereomeric C9-Hydroxyalkyl-5-phenylmorphans. Molecules (Basel, Switzerland) 28 (12) (2023)
Ross van de Wetering, Amy Ewald, Susan Welsh, Lindsay Kornberger, Samuel E Williamson, Bryan D McElroy, Eduardo R Butelman, Thomas Edward Prisinzano, Bronwyn M Kivell
The Kappa Opioid Receptor Agonist 16-Bromo Salvinorin A Has Anti-Cocaine Effects without Significant Effects on Locomotion, Food Reward, Learning and Memory, or Anxiety and Depressive-like Behaviors. Molecules (Basel, Switzerland) 28 (12) (2023)
Madhurima Das, George W Ward, Agnieszka Sulima, Dan Luo, Thomas Edward Prisinzano, Gregory H Imler, Andrew T Kerr, Arthur E Jacobson, Kenner C Rice
Potent MOR Agonists from 2'-Hydroxy-5,9-dimethyl- N -phenethyl Substituted-6,7-benzomorphans and from C8-Hydroxy, Methylene and Methyl Derivatives of N -Phenethylnormetazocine. Molecules (Basel, Switzerland) 28 (23) (2023)
Fuying Li, Theresa A Kopajtic, Jonathan L Katz, Dan Luo, Thomas Edward Prisinzano, Gregory H Imler, Jeffrey R Deschamps, Arthur E Jacobson, Kenner C Rice
Synthesis and Pharmacological Evaluation of Enantiopure N-Substituted Ortho-c Oxide-Bridged 5-Phenylmorphans. Molecules (Basel, Switzerland) 27 (24) (2022)
Fuying Li, Theresa A Kopajtic, Jonathan L Katz, Dan Luo, Thomas Edward Prisinzano, Gregory H Imler, Jeffrey R Deschamps, Arthur E Jacobson, Kenner C Rice
Synthesis and Pharmacological Evaluation of Enantiopure N-Substituted Ortho-c Oxide-Bridged 5-Phenylmorphans. Molecules (Basel, Switzerland) 27 (24) (2022)
Fuying Li, Theresa A Kopajtic, Jonathan L Katz, Dan Luo, Thomas Edward Prisinzano, Gregory H Imler, Jeffrey R Deschamps, Arthur E Jacobson, Kenner C Rice
Synthesis and Pharmacological Evaluation of Enantiopure N-Substituted Ortho-c Oxide-Bridged 5-Phenylmorphans. Molecules (Basel, Switzerland) 27 (24) (2022)
Fuying Li, Theresa A Kopajtic, Jonathan L Katz, Dan Luo, Thomas Edward Prisinzano, Gregory H Imler, Jeffrey R Deschamps, Arthur E Jacobson, Kenner C Rice
Synthesis and Pharmacological Evaluation of Enantiopure N-Substituted Ortho-c Oxide-Bridged 5-Phenylmorphans. Molecules (Basel, Switzerland) 27 (24) (2022)
Fuying Li, Theresa A Kopajtic, Jonathan L Katz, Dan Luo, Thomas Edward Prisinzano, Gregory H Imler, Jeffrey R Deschamps, Arthur E Jacobson, Kenner C Rice
Synthesis and Pharmacological Evaluation of Enantiopure N-Substituted Ortho-c Oxide-Bridged 5-Phenylmorphans. Molecules (Basel, Switzerland) 27 (24) (2022)
Dana R Chambers, Agnieszka Sulima, Dan Luo, Thomas Edward Prisinzano, Alexander Goldberg, Bing Xie, Lei Shi, Carol A Paronis, Jack Bergman, Nima Nassehi, Dana E Selley, Gregory H Imler, Arthur E Jacobson, Kenner C Rice
A Journey through Diastereomeric Space: The Design, Synthesis, In Vitro and In Vivo Pharmacological Activity, and Molecular Modeling of Novel Potent Diastereomeric MOR Agonists and Antagonists. Molecules (Basel, Switzerland) 27 (19) (2022)
Fuying Li, Theresa A Kopajtic, Jonathan L Katz, Dan Luo, Thomas Edward Prisinzano, Gregory H Imler, Jeffrey R Deschamps, Arthur E Jacobson, Kenner C Rice
Synthesis and Pharmacological Evaluation of Enantiopure N-Substituted Ortho-c Oxide-Bridged 5-Phenylmorphans. Molecules (Basel, Switzerland) 27 (24) (2022)
Sidnee L Hedrick, Dan Luo, Sophia Kaska, Kumar Kulldeep Niloy, Karen Jackson, Rupam Sarma, Jamie Horn, Caroline Baynard, Markos Leggas, Eduardo R Butelman, Mary Jeanne Kreek, Thomas Edward Prisinzano
Design, synthesis, and preliminary evaluation of a potential synthetic opioid rescue agent. Journal of biomedical science 28 (1) (2021)
Thomas Edward Prisinzano, Dennis C Liotta
NeuroChat with Professor Thomas E. Prisinzaro. ACS chemical neuroscience 11 (24) (2021)
Lisa Denny, Afnan Al Abadey, Katharina Robichon, Nikki Templeton, Thomas Edward Prisinzano, Bronwyn M Kivell, Anne Camille La Flamme
Nalfurafine reduces neuroinflammation and drives remyelination in models of CNS demyelinating disease. Clinical & translational immunology 10 (1) (2021)
Eduardo Roque Butelman, Caroline Baynard, Bryan D McElroy, Thomas Edward Prisinzano, Mary Jeanne Kreek
Profile of a short-acting κ-antagonist, LY2795050, on self-grooming behaviors, forced swim test and locomotor activity: sex comparison in mice. Journal of psychopharmacology (Oxford, England) 35 (5) (2021)
Eugene S Gutman, Eric Bow, Fuying Li, Agnieszka Sulima, Sophia Kaska, Rachel Crowley, Thomas Edward Prisinzano, Yong-Sok Lee, Sergio A Hassan, Gregory H Imler, Jeffrey R Deschamps, Arthur E Jacobson, Kenner C Rice
G-Protein biased opioid agonists: 3-hydroxy-N-phenethyl-5-phenylmorphans with three-carbon chain substituents at C9. RSC medicinal chemistry 11 (8) (2020)
Rachel S Crowley, Andrew P Riley, Amy F Alder, Richard J Anderson, Dan Luo, Sophia Kaska, Pamela Maynez, Bronwyn M Kivell, Thomas Edward Prisinzano
Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Design, Synthesis, and Evaluation of Analogues with Improved Potency and G-protein Activation Bias at the μ-Opioid Receptor. ACS chemical neuroscience 11 (12) (2020)
Bronwyn M Kivell, Kelly F Paton, Nitin Kumar, Aashish S Morani, Aimee Culverhouse, Amy Shepherd, Susan A Welsh, Andrew Biggerstaff, Rachel S Crowley, Thomas Edward Prisinzano
Kappa Opioid Receptor Agonist Mesyl Sal B Attenuates Behavioral Sensitization to Cocaine with Fewer Aversive Side-Effects than Salvinorin A in Rodents. Molecules (Basel, Switzerland) 23 (10) (2018)
Trey A Ronnebaum, Jeffrey S McFarlane, Thomas Edward Prisinzano, Squire J Booker, Audrey L Lamb
Stuffed Methyltransferase Catalyzes the Penultimate Step of Pyochelin Biosynthesis. Biochemistry 58 (6) (2018)
Alexander M Sherwood, Samuel E Williamson, Stephanie N Johnson, Anil Yilmaz, Victor W Day, Thomas Edward Prisinzano
Scalable Regioselective and Stereoselective Synthesis of Functionalized (E)-4-Iodobut-3-en-1-ols: Gram-Scale Total Synthesis of Fungal Decanolides and Derivatives. The Journal of organic chemistry 83 (2) (2018)
Somnath Narayan Karad, Mohan Pal, Rachel S Crowley, Thomas Edward Prisinzano, Ryan A Altman
Synthesis and Opioid Activity of Tyr1 -ψ[(Z)CF=CH]-Gly2 and Tyr1 -ψ[(S)/(R)-CF3 CH-NH]-Gly2 Leu-enkephalin Fluorinated Peptidomimetics. ChemMedChem 12 (8) (2017)
Kimberly M Lovell, Kevin J Frankowski, Edward L Stahl, Stephen R Slauson, Euna Yoo, Thomas Edward Prisinzano, Jeffrey Aubé, Laura M Bohn
Correction to "Structure-Activity Relationship Studies of Functionally Selective Kappa Opioid Receptor Agonists that Modulate ERK 1/2 Phosphorylation While Preserving G Protein Over βArrestin2 Signaling Bias". ACS chemical neuroscience 8 (7) (2017)
Anil Yilmaz, Rachel Saylor Crowley, Alexander M Sherwood, Thomas Edward Prisinzano
Semisynthesis and Kappa-Opioid Receptor Activity of Derivatives of Columbin, a Furanolactone Diterpene. Journal of natural products 80 (7) (2017)
Alexander M Sherwood, Rachel Saylor Crowley, Kelly F Paton, Andrew Biggerstaff, Benjamin Neuenswander, Victor W Day, Bronwyn M Kivell, Thomas Edward Prisinzano
Addressing Structural Flexibility at the A-Ring on Salvinorin A: Discovery of a Potent Kappa-Opioid Agonist with Enhanced Metabolic Stability. Journal of medicinal chemistry 60 (9) (2017)
Alexander M Sherwood, Samuel E Williamson, Rachel S Crowley, Logan M Abbott, Victor W Day, Thomas Edward Prisinzano
Modular Approach to pseudo-Neoclerodanes as Designer κ-Opioid Ligands. Organic letters 19 (19) (2017)
Rachel Saylor Crowley, Andrew P Riley, Alexander M Sherwood, Chad E Groer, Nirajmohan Shivaperumal, Miguel Biscaia, Kelly Paton, Sebastian Schneider, Davide Provasi, Bronwyn M Kivell, Marta Filizola, Thomas Edward Prisinzano
Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Identification of a Potent and Centrally Acting μ Opioid Analgesic with Reduced Abuse Liability. Journal of medicinal chemistry 59 (24) (2016)

Thomas Edward Prisinzano.css-eqlu8i{font-size:small;padding-left:4px;} (Thomas E Prisinzano)

Publication Activity (10 Years)

Top Topics

Top Venues

Thomas Edward Prisinzano (Thomas E Prisinzano)