Thomas M Polasek

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 22

Top Topics

Molecularly Imprinted

Major Depressive Disorder

Top Venues

CPT: pharmacometrics & systems pharmacology

Clinical pharmacology and therapeutics

Therapeutic advances in drug safety

This page only lists publications with an associated author ORCID identifier.

Publications

Iris K Minichmayr, Tomoyuki Mizuno, Srijib Goswami, Richard Wilson Peck, Thomas M Polasek, null null
Recent Advances Addressing the Challenges of Precision Dosing. Clinical pharmacology and therapeutics 116 (3) (2024)
Sam Mostafa, Reza Rafizadeh, Thomas M Polasek, Chad A Bousman, Amin Rostami-Hodjegan, Robert M Stowe, Prescilla Carrion, Leslie J Sheffield, Carl M J Kirkpatrick
Virtual twins for model-informed precision dosing of clozapine in patients with treatment-resistant schizophrenia. CPT: pharmacometrics & systems pharmacology 13 (3) (2024)
Thomas M Polasek, Richard Wilson Peck
Beyond Population-Level Targets for Drug Concentrations: Precision Dosing Needs Individual-Level Targets that Include Superior Biomarkers of Drug Responses. Clinical pharmacology and therapeutics 116 (3) (2024)
Sam Mostafa, Reza Rafizadeh, Thomas M Polasek, Chad A Bousman, Amin Rostami-Hodjegan, Robert M Stowe, Prescilla Carrion, Leslie J Sheffield, Carl M J Kirkpatrick
Virtual twins for model-informed precision dosing of clozapine in patients with treatment-resistant schizophrenia. CPT: pharmacometrics & systems pharmacology (2024)
Iris K Minichmayr, Tomoyuki Mizuno, Srijib Goswami, Richard Wilson Peck, Thomas M Polasek, null null
Recent Advances Addressing the Challenges of Precision Dosing. Clinical pharmacology and therapeutics (2024)
Thomas M Polasek, Richard Wilson Peck
Beyond Population-Level Targets for Drug Concentrations: Precision Dosing Needs Individual-Level Targets that Include Superior Biomarkers of Drug Responses. Clinical pharmacology and therapeutics (2024)
Sam Mostafa, Reza Rafizadeh, Thomas M Polasek, Chad A Bousman, Amin Rostami-Hodjegan, Robert M Stowe, Prescilla Carrion, Leslie J Sheffield, Carl M J Kirkpatrick
Virtual twins for model-informed precision dosing of clozapine in patients with treatment-resistant schizophrenia. CPT: pharmacometrics & systems pharmacology 13 (3) (2024)
Sam Mostafa, Reza Rafizadeh, Thomas M Polasek, Chad A Bousman, Amin Rostami-Hodjegan, Robert M Stowe, Prescilla Carrion, Leslie J Sheffield, Carl M J Kirkpatrick
Virtual twins for model-informed precision dosing of clozapine in patients with treatment-resistant schizophrenia. CPT: pharmacometrics & systems pharmacology 13 (3) (2024)
Sam Mostafa, Reza Rafizadeh, Thomas M Polasek, Chad A Bousman, Amin Rostami-Hodjegan, Robert M Stowe, Prescilla Carrion, Leslie J Sheffield, Carl M J Kirkpatrick
Virtual twins for model-informed precision dosing of clozapine in patients with treatment-resistant schizophrenia. CPT: pharmacometrics & systems pharmacology 13 (3) (2024)
Sam Mostafa, Reza Rafizadeh, Thomas M Polasek, Chad A Bousman, Amin Rostami-Hodjegan, Robert M Stowe, Prescilla Carrion, Leslie J Sheffield, Carl M J Kirkpatrick
Virtual twins for model-informed precision dosing of clozapine in patients with treatment-resistant schizophrenia. CPT: pharmacometrics & systems pharmacology 13 (3) (2024)
Sibel Saya, Patty Chondros, Anastasia Gardner, Cathrine Mihalopolous, Mary Lou Chatterton, Jane Maree Gunn, Timothy Frank Chen, Thomas M Polasek, Elise Dettmann, Rachel Brooks, Michelle King, Luke Spencer, Pavithran Alphonse, Shakira R Onwuka, Georgia Ramsay, Zoe Siviour, Jamie Jm Liew, Philip Ly, Matthew Thoenig, Raushaan Seychell, Floriana La Rocca, Luke B Hesson, Nydia Mejias, Terri Sivertsen, Melanie Anne Galea, Chad A Bousman, Jon David Emery
The PRESIDE (PhaRmacogEnomicS In DEpression) Trial: a double-blind randomised controlled trial of pharmacogenomic-informed prescribing of antidepressants on depression outcomes in patients with major depressive disorder in primary care. Trials 24 (1) (2023)
Sibel Saya, Patty Chondros, Anastasia Gardner, Cathrine Mihalopolous, Mary Lou Chatterton, Jane Maree Gunn, Timothy Frank Chen, Thomas M Polasek, Elise Dettmann, Rachel Brooks, Michelle King, Luke Spencer, Pavithran Alphonse, Shakira R Onwuka, Georgia Ramsay, Zoe Siviour, Jamie Jm Liew, Philip Ly, Matthew Thoenig, Raushaan Seychell, Floriana La Rocca, Luke B Hesson, Nydia Mejias, Terri Sivertsen, Melanie Anne Galea, Chad A Bousman, Jon David Emery
The PRESIDE (PhaRmacogEnomicS In DEpression) Trial: a double-blind randomised controlled trial of pharmacogenomic-informed prescribing of antidepressants on depression outcomes in patients with major depressive disorder in primary care. Trials 24 (1) (2023)
Sibel Saya, Patty Chondros, Anastasia Gardner, Cathrine Mihalopolous, Mary Lou Chatterton, Jane Maree Gunn, Timothy Frank Chen, Thomas M Polasek, Elise Dettmann, Rachel Brooks, Michelle King, Luke Spencer, Pavithran Alphonse, Shakira R Onwuka, Georgia Ramsay, Zoe Siviour, Jamie Jm Liew, Philip Ly, Matthew Thoenig, Raushaan Seychell, Floriana La Rocca, Luke B Hesson, Nydia Mejias, Terri Sivertsen, Melanie Anne Galea, Chad A Bousman, Jon David Emery
The PRESIDE (PhaRmacogEnomicS In DEpression) Trial: a double-blind randomised controlled trial of pharmacogenomic-informed prescribing of antidepressants on depression outcomes in patients with major depressive disorder in primary care. Trials 24 (1) (2023)
Brahim Achour, Pauline Gosselin, Jean Terrier, Yvonne Gloor, Zubida M Al-Majdoub, Thomas M Polasek, Youssef Daali, Amin Rostami-Hodjegan, Jean-Luc Reny
Liquid Biopsy for Patient Characterization in Cardiovascular Disease: Verification against Markers of Cytochrome P450 and P-Glycoprotein Activities. Clinical pharmacology and therapeutics 111 (6) (2022)
Sam Mostafa, Thomas M Polasek, Chad A Bousman, Daniel J Mueller, Leslie J Sheffield, Joel Rembach, Carl M J Kirkpatrick
Pharmacogenomics in psychiatry - the challenge of cytochrome P450 enzyme phenoconversion and solutions to assist precision dosing. Pharmacogenomics 23 (15) (2022)
Sebastian Levesque, Thomas M Polasek, Eric Haan, Sepehr Shakib
Attitudes of healthy volunteers to genetic testing in phase 1 clinical trials. F1000Research 10 (2021)
Thomas M Polasek, Sepehr Shakib, Amin Rostami-Hodjegan
Precision medicine technology hype or reality? The example of computer-guided dosing. F1000Research 8 (2019)
Thomas M Polasek, Carl M J Kirkpatrick, Amin Rostami-Hodjegan
Precision dosing to avoid adverse drug reactions. Therapeutic advances in drug safety 10 (2019)
Thomas M Polasek, Amin Rostami-Hodjegan, Dong-Seok Yim, Masoud Jamei, Howard Lee, Holly Kimko, Jae Kyoung Kim, Phuong Thi Thu Nguyen, Adam S Darwich, Jae-Gook Shin
What Does it Take to Make Model-Informed Precision Dosing Common Practice? Report from the 1st Asian Symposium on Precision Dosing. The AAPS journal 21 (2) (2019)
Andrew Rowland, Madelé van Dyk, Ashley M Hopkins, Reham Mounzer, Thomas M Polasek, Amin Rostami-Hodjegan, Michael J Sorich
Physiologically Based Pharmacokinetic Modeling to Identify Physiological and Molecular Characteristics Driving Variability in Drug Exposure. Clinical pharmacology and therapeutics 104 (6) (2018)
Thomas M Polasek, Geoffrey T Tucker, Michael J Sorich, Michael D Wiese, Titus Mohan, Amin Rostami-Hodjegan, Porntipa Korprasertthaworn, Vidya Perera, Andrew Rowland
Prediction of olanzapine exposure in individual patients using physiologically based pharmacokinetic modelling and simulation. British journal of clinical pharmacology 84 (3) (2018)
Thomas M Polasek, Matthew P Doogue, Tilenka R J Thynne
Metformin treatment of type 2 diabetes mellitus in pregnancy: update on safety and efficacy. Therapeutic advances in drug safety 9 (6) (2018)