Tim Clausen

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 29

Top Venues

Nature communications

eLife

Science (New York, N.Y.)

Nature chemical biology

Research Institute of Molecular Pathology (IMP)

Max-Planck-Insitute of Biochemistry (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Research Institute of Molecular Pathology (IMP) Aug 01 2009

Austria

Senior Group Leader

Research Institute of Molecular Pathology (IMP) Nov 01 2002 - Jul 31 2009

Austria

Group Leader

Education History

Max-Planck-Insitute of Biochemistry Aug 01 1994 - Dec 15 1997

Germany

PHD :: Macromolecular Crystallography

University of Constance Jun 30 1993 - Jun 30 1994

Germany

MSC :: Department of Organic Biochemistry

Publications

Lukas Junk, Volker M Schmiedel, Somraj Guha, Katharina Fischel, Peter Greb, Kristin Vill, Violetta Krisilia, Lasse van Geelen, Klaus Rumpel, Parvinder Kaur, Ramya V Krishnamurthy, Shridhar Narayanan, Radha Krishan Shandil, Mayas Singh, Christiane Kofink, Andreas Mantoulidis, Philipp Biber, Gerhard Gmaschitz, Uli Kazmaier, Anton Meinhart, Julia Leodolter, David Hoi, Sabryna Junker, Francesca Ester Morreale, Tim Clausen, Rainer Kalscheuer, Harald Weinstabl, Guido Boehmelt
Homo-BacPROTAC-induced degradation of ClpC1 as a strategy against drug-resistant mycobacteria. Nature communications 15 (1) (2024)
Nathalie Beaufort, Linda Ingendahl, Melisa Merdanovic, Andree Schmidt, David Podlesainski, Tim Richter, Thorben Neumann, Michael Kuszner, Ingrid R Vetter, Patricia Stege, Steven G Burston, Anto Filipovic, Yasser B Ruiz-Blanco, Kenny Bravo-Rodriguez, Joel Mieres Perez, Christine Beuck, Stephan Uebel, Monika Zobawa, Jasmin Schillinger, Rainer Malik, Katalin Todorov-Völgyi, Juliana Rey, Annabell Roberti, Birte Hagemeier, Benedikt Wefers, Stephan A Müller, Wolfgang Wurst, Elsa Sanchez-Garcia, Alexander Zimmermann, Xiao-Yu Hu, Tim Clausen, Robert Huber, Stefan F Lichtenthaler, Carsten Schmuck, Michael Giese, Markus Kaiser, Michael Ehrmann, Martin Dichgans
Rational correction of pathogenic conformational defects in HTRA1. Nature communications 15 (1) (2024)
Antonia Vogel, Renato Arnese, Ricardo M Gudino Carrillo, Daria Sehr, Luiza Deszcz, Andrzej Bylicki, Anton Meinhart, Tim Clausen
UNC-45 assisted myosin folding depends on a conserved FX 3 HY motif implicated in Freeman Sheldon Syndrome. Nature communications 15 (1) (2024)
Nathalie Beaufort, Linda Ingendahl, Melisa Merdanovic, Andree Schmidt, David Podlesainski, Tim Richter, Thorben Neumann, Michael Kuszner, Ingrid R Vetter, Patricia Stege, Steven G Burston, Anto Filipovic, Yasser B Ruiz-Blanco, Kenny Bravo-Rodriguez, Joel Mieres Perez, Christine Beuck, Stephan Uebel, Monika Zobawa, Jasmin Schillinger, Rainer Malik, Katalin Todorov-Völgyi, Juliana Rey, Annabell Roberti, Birte Hagemeier, Benedikt Wefers, Stephan A Müller, Wolfgang Wurst, Elsa Sanchez-Garcia, Alexander Zimmermann, Xiao-Yu Hu, Tim Clausen, Robert Huber, Stefan F Lichtenthaler, Carsten Schmuck, Michael Giese, Markus Kaiser, Michael Ehrmann, Martin Dichgans
Rational correction of pathogenic conformational defects in HTRA1. Nature communications 15 (1) (2024)
Lukas Junk, Volker M Schmiedel, Somraj Guha, Katharina Fischel, Peter Greb, Kristin Vill, Violetta Krisilia, Lasse van Geelen, Klaus Rumpel, Parvinder Kaur, Ramya V Krishnamurthy, Shridhar Narayanan, Radha Krishan Shandil, Mayas Singh, Christiane Kofink, Andreas Mantoulidis, Philipp Biber, Gerhard Gmaschitz, Uli Kazmaier, Anton Meinhart, Julia Leodolter, David Hoi, Sabryna Junker, Francesca Ester Morreale, Tim Clausen, Rainer Kalscheuer, Harald Weinstabl, Guido Boehmelt
Homo-BacPROTAC-induced degradation of ClpC1 as a strategy against drug-resistant mycobacteria. Nature communications 15 (1) (2024)
Nathalie Beaufort, Linda Ingendahl, Melisa Merdanovic, Andree Schmidt, David Podlesainski, Tim Richter, Thorben Neumann, Michael Kuszner, Ingrid R Vetter, Patricia Stege, Steven G Burston, Anto Filipovic, Yasser B Ruiz-Blanco, Kenny Bravo-Rodriguez, Joel Mieres Perez, Christine Beuck, Stephan Uebel, Monika Zobawa, Jasmin Schillinger, Rainer Malik, Katalin Todorov-Völgyi, Juliana Rey, Annabell Roberti, Birte Hagemeier, Benedikt Wefers, Stephan A Müller, Wolfgang Wurst, Elsa Sanchez-Garcia, Alexander Zimmermann, Xiao-Yu Hu, Tim Clausen, Robert Huber, Stefan F Lichtenthaler, Carsten Schmuck, Michael Giese, Markus Kaiser, Michael Ehrmann, Martin Dichgans
Rational correction of pathogenic conformational defects in HTRA1. Nature communications 15 (1) (2024)
Lukas Junk, Volker M Schmiedel, Somraj Guha, Katharina Fischel, Peter Greb, Kristin Vill, Violetta Krisilia, Lasse van Geelen, Klaus Rumpel, Parvinder Kaur, Ramya V Krishnamurthy, Shridhar Narayanan, Radha Krishan Shandil, Mayas Singh, Christiane Kofink, Andreas Mantoulidis, Philipp Biber, Gerhard Gmaschitz, Uli Kazmaier, Anton Meinhart, Julia Leodolter, David Hoi, Sabryna Junker, Francesca Ester Morreale, Tim Clausen, Rainer Kalscheuer, Harald Weinstabl, Guido Boehmelt
Homo-BacPROTAC-induced degradation of ClpC1 as a strategy against drug-resistant mycobacteria. Nature communications 15 (1) (2024)
Lukas Junk, Volker M Schmiedel, Somraj Guha, Katharina Fischel, Peter Greb, Kristin Vill, Violetta Krisilia, Lasse van Geelen, Klaus Rumpel, Parvinder Kaur, Ramya V Krishnamurthy, Shridhar Narayanan, Radha Krishan Shandil, Mayas Singh, Christiane Kofink, Andreas Mantoulidis, Philipp Biber, Gerhard Gmaschitz, Uli Kazmaier, Anton Meinhart, Julia Leodolter, David Hoi, Sabryna Junker, Francesca Ester Morreale, Tim Clausen, Rainer Kalscheuer, Harald Weinstabl, Guido Boehmelt
Homo-BacPROTAC-induced degradation of ClpC1 as a strategy against drug-resistant mycobacteria. Nature communications 15 (1) (2024)
Nathalie Beaufort, Linda Ingendahl, Melisa Merdanovic, Andree Schmidt, David Podlesainski, Tim Richter, Thorben Neumann, Michael Kuszner, Ingrid R Vetter, Patricia Stege, Steven G Burston, Anto Filipovic, Yasser B Ruiz-Blanco, Kenny Bravo-Rodriguez, Joel Mieres Perez, Christine Beuck, Stephan Uebel, Monika Zobawa, Jasmin Schillinger, Rainer Malik, Katalin Todorov-Völgyi, Juliana Rey, Annabell Roberti, Birte Hagemeier, Benedikt Wefers, Stephan A Müller, Wolfgang Wurst, Elsa Sanchez-Garcia, Alexander Zimmermann, Xiao-Yu Hu, Tim Clausen, Robert Huber, Stefan F Lichtenthaler, Carsten Schmuck, Michael Giese, Markus Kaiser, Michael Ehrmann, Martin Dichgans
Rational correction of pathogenic conformational defects in HTRA1. Nature communications 15 (1) (2024)
Lukas Junk, Volker M Schmiedel, Somraj Guha, Katharina Fischel, Peter Greb, Kristin Vill, Violetta Krisilia, Lasse van Geelen, Klaus Rumpel, Parvinder Kaur, Ramya V Krishnamurthy, Shridhar Narayanan, Radha Krishan Shandil, Mayas Singh, Christiane Kofink, Andreas Mantoulidis, Philipp Biber, Gerhard Gmaschitz, Uli Kazmaier, Anton Meinhart, Julia Leodolter, David Hoi, Sabryna Junker, Francesca Ester Morreale, Tim Clausen, Rainer Kalscheuer, Harald Weinstabl, Guido Boehmelt
Homo-BacPROTAC-induced degradation of ClpC1 as a strategy against drug-resistant mycobacteria. Nature communications 15 (1) (2024)
Lukas Junk, Volker M Schmiedel, Somraj Guha, Katharina Fischel, Peter Greb, Kristin Vill, Violetta Krisilia, Lasse van Geelen, Klaus Rumpel, Parvinder Kaur, Ramya V Krishnamurthy, Shridhar Narayanan, Radha Krishan Shandil, Mayas Singh, Christiane Kofink, Andreas Mantoulidis, Philipp Biber, Gerhard Gmaschitz, Uli Kazmaier, Anton Meinhart, Julia Leodolter, David Hoi, Sabryna Junker, Francesca Ester Morreale, Tim Clausen, Rainer Kalscheuer, Harald Weinstabl, Guido Boehmelt
Homo-BacPROTAC-induced degradation of ClpC1 as a strategy against drug-resistant mycobacteria. Nature communications 15 (1) (2024)
Antonia Vogel, Renato Arnese, Ricardo M Gudino Carrillo, Daria Sehr, Luiza Deszcz, Andrzej Bylicki, Anton Meinhart, Tim Clausen
UNC-45 assisted myosin folding depends on a conserved FX 3 HY motif implicated in Freeman Sheldon Syndrome. Nature communications 15 (1) (2024)
Lukas Junk, Volker M Schmiedel, Somraj Guha, Katharina Fischel, Peter Greb, Kristin Vill, Violetta Krisilia, Lasse van Geelen, Klaus Rumpel, Parvinder Kaur, Ramya V Krishnamurthy, Shridhar Narayanan, Radha Krishan Shandil, Mayas Singh, Christiane Kofink, Andreas Mantoulidis, Philipp Biber, Gerhard Gmaschitz, Uli Kazmaier, Anton Meinhart, Julia Leodolter, David Hoi, Sabryna Junker, Francesca Ester Morreale, Tim Clausen, Rainer Kalscheuer, Harald Weinstabl, Guido Boehmelt
Homo-BacPROTAC-induced degradation of ClpC1 as a strategy against drug-resistant mycobacteria. Nature communications 15 (1) (2024)
Sara Scinicariello, Adrian Soderholm, Markus Schäfer, Alexandra Shulkina, Irene Schwartz, Kathrin Hacker, Rebeca Gogova, Robert Kalis, Kimon Froussios, Valentina Budroni, Annika Bestehorn, Tim Clausen, Pavel Kovarik, Johannes Zuber, Gijs A Versteeg
HUWE1 controls tristetraprolin proteasomal degradation by regulating its phosphorylation. eLife 12 (2023)
Sara Scinicariello, Adrian Soderholm, Markus Schäfer, Alexandra Shulkina, Irene Schwartz, Kathrin Hacker, Rebeca Gogova, Robert Kalis, Kimon Froussios, Valentina Budroni, Annika Bestehorn, Tim Clausen, Pavel Kovarik, Johannes Zuber, Gijs A Versteeg
HUWE1 controls tristetraprolin proteasomal degradation by regulating its phosphorylation. eLife 12 (2023)
Julian F Ehrmann, Daniel B Grabarczyk, Maria Heinke, Luiza Deszcz, Robert Kurzbauer, Otto Hudecz, Alexandra Shulkina, Rebeca Gogova, Anton Meinhart, Gijs A Versteeg, Tim Clausen
Structural basis for regulation of apoptosis and autophagy by the BIRC6/SMAC complex. Science (New York, N.Y.) 379 (6637) (2023)
Julian F Ehrmann, Daniel B Grabarczyk, Maria Heinke, Luiza Deszcz, Robert Kurzbauer, Otto Hudecz, Alexandra Shulkina, Rebeca Gogova, Anton Meinhart, Gijs A Versteeg, Tim Clausen
Structural basis for regulation of apoptosis and autophagy by the BIRC6/SMAC complex. Science (New York, N.Y.) 379 (6637) (2023)
Julian F Ehrmann, Daniel B Grabarczyk, Maria Heinke, Luiza Deszcz, Robert Kurzbauer, Otto Hudecz, Alexandra Shulkina, Rebeca Gogova, Anton Meinhart, Gijs A Versteeg, Tim Clausen
Structural basis for regulation of apoptosis and autophagy by the BIRC6/SMAC complex. Science (New York, N.Y.) (2023)
Julian F Ehrmann, Daniel B Grabarczyk, Maria Heinke, Luiza Deszcz, Robert Kurzbauer, Otto Hudecz, Alexandra Shulkina, Rebeca Gogova, Anton Meinhart, Gijs A Versteeg, Tim Clausen
Structural basis for regulation of apoptosis and autophagy by the BIRC6/SMAC complex. Science (New York, N.Y.) 379 (6637) (2023)
Juliana Rey, Maike Breiden, Vanda Lux, Anika Bluemke, Maike Steindel, Kamilla Ripkens, Bastian Möllers, Kenny Bravo Rodriguez, Prisca Boisguerin, Rudolf Volkmer, Joel Mieres Perez, Tim Clausen, Elsa Sanchez-Garcia, Michael Ehrmann
An allosteric HTRA1-calpain 2 complex with restricted activation profile. Proceedings of the National Academy of Sciences of the United States of America 119 (14) (2022)
Daniel B Grabarczyk, Olga A Petrova, Luiza Deszcz, Robert Kurzbauer, Paul Murphy, Juraj Ahel, Antonia Vogel, Rebeca Gogova, Victoria Faas, Darja Kordic, Alexander Schleiffer, Anton Meinhart, Richard Imre, Anita Lehner, Jana Neuhold, Gerd Bader, Peggy Stolt-Bergner, Jark Böttcher, Bernhard Wolkerstorfer, Gerhard Fischer, Irina Grishkovskaya, David Haselbach, Dirk Kessler, Tim Clausen
HUWE1 employs a giant substrate-binding ring to feed and regulate its HECT E3 domain. Nature chemical biology 17 (10) (2021)
Alan Rodriguez Carvajal, Irina Grishkovskaya, Carlos Gomez-Diaz, Antonia Vogel, Adar Sonn-Segev, Manish S Kushwah, Katrin Schodl, Luiza Deszcz, Zsuzsanna Orban-Nemeth, Shinji Sakamoto, Karl Mechtler, Philipp Kukura, Tim Clausen, David Haselbach, Fumiyo Ikeda
The linear ubiquitin chain assembly complex (LUBAC) generates heterotypic ubiquitin chains. eLife 10 (2021)
Bence Hajdusits, Marcin Józef Suskiewicz, Nikolas Hundt, Anton Meinhart, Robert Kurzbauer, Julia Leodolter, Philipp Kukura, Tim Clausen
McsB forms a gated kinase chamber to mark aberrant bacterial proteins for degradation. eLife 10 (2021)
Madlen Stephani, Lorenzo Picchianti, Alexander Gajic, Rebecca Beveridge, Emilio Skarwan, Victor Sanchez de Medina Hernandez, Azadeh Mohseni, Marion Clavel, Yonglun Zeng, Christin Naumann, Mateusz Matuszkiewicz, Eleonora Turco, Christian Loefke, Baiying Li, Gerhard Dürnberger, Michael Schutzbier, Hsiao Tieh Chen, Alibek Abdrakhmanov, Adriana Savova, Khong-Sam Chia, Armin Djamei, Irene Schaffner, Steffen Abel, Liwen Jiang, Karl Mechtler, Fumiyo Ikeda, Sascha Martens, Tim Clausen, Yasin F Dagdas
A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stress. eLife 9 (2020)
Juraj Ahel, Anita Lehner, Antonia Vogel, Alexander Schleiffer, Anton Meinhart, David Haselbach, Tim Clausen
Moyamoya disease factor RNF213 is a giant E3 ligase with a dynein-like core and a distinct ubiquitin-transfer mechanism. eLife 9 (2020)
Doris Hellerschmied, Anita Lehner, Nina Franicevic, Renato Arnese, Chloe A Johnson, Antonia Vogel, Anton Meinhart, Robert Kurzbauer, Luiza Deszcz, Linn Gazda, Michael A Geeves, Tim Clausen
Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin. Nature communications 10 (1) (2019)
Marcin J Suskiewicz, Bence Hajdusits, Rebecca Beveridge, Alexander Heuck, Lam Dai Vu, Robert Kurzbauer, Katja Hauer, Vanessa Thoeny, Klaus Rumpel, Karl Mechtler, Anton Meinhart, Tim Clausen
Structure of McsB, a protein kinase for regulated arginine phosphorylation. Nature chemical biology 15 (5) (2019)
Doris Hellerschmied, Max Roessler, Anita Lehner, Linn Gazda, Karel Stejskal, Richard Imre, Karl Mechtler, Alexander Dammermann, Tim Clausen
UFD-2 is an adaptor-assisted E3 ligase targeting unfolded proteins. Nature communications 9 (1) (2018)
Alexander Heuck, Sonja Schitter-Sollner, Marcin Józef Suskiewicz, Robert Kurzbauer, Juliane Kley, Alexander Schleiffer, Pascaline Rombaut, Franz Herzog, Tim Clausen
Structural basis for the disaggregase activity and regulation of Hsp104. eLife 5 (2016)

Tim Clausen.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Tim Clausen