Alexander Schleiffer

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 29

Top Topics

Transcription Factor

Circulating Tumor

Top Venues

The EMBO journal

Nature communications

Science (New York, N.Y.)

This page only lists publications with an associated author ORCID identifier.

Publications

Lisa Baumgartner, Jonathan J Ipsaro, Ulrich Hohmann, Dominik Handler, Alexander Schleiffer, Peter Duchek, Julius Brennecke
Evolutionary adaptation of an HP1-protein chromodomain integrates chromatin and DNA sequence signals. eLife 13 (2024)
Lisa Baumgartner, Jonathan J Ipsaro, Ulrich Hohmann, Dominik Handler, Alexander Schleiffer, Peter Duchek, Julius Brennecke
Evolutionary adaptation of an HP1-protein chromodomain integrates chromatin and DNA sequence signals. eLife 13 (2024)
Ignacio Prusén Mota, Marta Galova, Alexander Schleiffer, Tan-Trung Nguyen, Ines Kovacikova, Carolina Farias Saad, Gabriele Litos, Tomoko Nishiyama, Juraj Gregan, Jan-Michael Peters, Peter Schlögelhofer
Sororin is an evolutionary conserved antagonist of WAPL. Nature communications 15 (1) (2024)
Lisa Baumgartner, Jonathan J Ipsaro, Ulrich Hohmann, Dominik Handler, Alexander Schleiffer, Peter Duchek, Julius Brennecke
Evolutionary adaptation of an HP1-protein chromodomain integrates chromatin and DNA sequence signals. eLife 13 (2024)
Ignacio Prusén Mota, Marta Galova, Alexander Schleiffer, Tan-Trung Nguyen, Ines Kovacikova, Carolina Farias Saad, Gabriele Litos, Tomoko Nishiyama, Juraj Gregan, Jan-Michael Peters, Peter Schlögelhofer
Sororin is an evolutionary conserved antagonist of WAPL. Nature communications 15 (1) (2024)
Ignacio Prusén Mota, Marta Galova, Alexander Schleiffer, Tan-Trung Nguyen, Ines Kovacikova, Carolina Farias Saad, Gabriele Litos, Tomoko Nishiyama, Juraj Gregan, Jan-Michael Peters, Peter Schlögelhofer
Sororin is an evolutionary conserved antagonist of WAPL. Nature communications 15 (1) (2024)
Ignacio Prusén Mota, Marta Galova, Alexander Schleiffer, Tan-Trung Nguyen, Ines Kovacikova, Carolina Farias Saad, Gabriele Litos, Tomoko Nishiyama, Juraj Gregan, Jan-Michael Peters, Peter Schlögelhofer
Sororin is an evolutionary conserved antagonist of WAPL. Nature communications 15 (1) (2024)
Zuzana Hodáková, Irina Grishkovskaya, Hanna L Brunner, Derek L Bolhuis, Katarina Belačić, Alexander Schleiffer, Harald Kotisch, Nicholas G Brown, David Haselbach
Cryo-EM structure of the chain-elongating E3 ubiquitin ligase UBR5. The EMBO journal (2023)
Krista R B Gert, Karin Panser, Joachim M Surm, Benjamin S Steinmetz, Alexander Schleiffer, Luca Jovine, Yehu Moran, Fyodor Kondrashov, Andrea Pauli
Divergent molecular signatures in fish Bouncer proteins define cross-fertilization boundaries. Nature communications 14 (1) (2023)
Jeroen Dobbelaere, Tiffany Y Su, Balazs Erdi, Alexander Schleiffer, Alexander Dammermann
A phylogenetic profiling approach identifies novel ciliogenesis genes in Drosophila and C. elegans. The EMBO journal (2023)
Loni Klaus, Bernardo P de Almeida, Anna Vlasova, Filip Nemčko, Alexander Schleiffer, Katharina Bergauer, Lorena Hofbauer, Martina Rath, Alexander Stark
Systematic identification and characterization of repressive domains in Drosophila transcription factors. The EMBO journal 42 (3) (2022)
Loni Klaus, Bernardo P de Almeida, Anna Vlasova, Filip Nemčko, Alexander Schleiffer, Katharina Bergauer, Lorena Hofbauer, Martina Rath, Alexander Stark
Systematic identification and characterization of repressive domains in Drosophila transcription factors. The EMBO journal 42 (3) (2022)
Loni Klaus, Bernardo P de Almeida, Anna Vlasova, Filip Nemčko, Alexander Schleiffer, Katharina Bergauer, Lorena Hofbauer, Martina Rath, Alexander Stark
Systematic identification and characterization of repressive domains in Drosophila transcription factors. The EMBO journal 42 (3) (2022)
Lukas Leiendecker, Tobias Neumann, Pauline S Jung, Shona M Cronin, Thomas L Steinacker, Alexander Schleiffer, Michael Schutzbier, Karl Mechtler, Kervarrec Thibault, Estelle Laurent, Kamel Bachiri, Etienne Coyaud, Rajmohan Murali, Klaus J Busam, Babak Itzinger-Monshi, Reinhard Kirnbauer, Lorenzo Cerroni, Eduardo Calonje, Arno Rutten, Frank Stubenrauch, Klaus Georg Griewank, Thomas Wiesner, Anna C Obenauf
Human papillomavirus 42 drives digital papillary adenocarcinoma and elicits a germ-cell like program conserved in HPV-positive cancers. Cancer discovery (2022)
Zeynep Kabakci, Heidi E Reichle, Bianca Lemke, Dorota Rousova, Samir Gupta, Joe Weber, Alexander Schleiffer, John R Weir, Christian F Lehner
Homologous chromosomes are stably conjoined for Drosophila male meiosis I by SUM, a multimerized protein assembly with modules for DNA-binding and for separase-mediated dissociation co-opted from cohesin. PLoS genetics 18 (12) (2022)
Loni Klaus, Bernardo P de Almeida, Anna Vlasova, Filip Nemčko, Alexander Schleiffer, Katharina Bergauer, Lorena Hofbauer, Martina Rath, Alexander Stark
Systematic identification and characterization of repressive domains in Drosophila transcription factors. The EMBO journal 42 (3) (2022)
Catarina Pechincha, Sven Groessl, Robert Kalis, Melanie de Almeida, Andrea Zanotti, Marten Wittmann, Martin Schneider, Rafael Paschoal de Campos, Sarah Rieser, Marlene Brandstetter, Alexander Schleiffer, Karin Müller-Decker, Dominic Helm, Sabrina Jabs, David Haselbach, Marius K Lemberg, Johannes Zuber, Wilhelm Palm
Lysosomal enzyme trafficking factor LYSET enables nutritional usage of extracellular proteins. Science (New York, N.Y.) 378 (6615) (2022)
Loni Klaus, Bernardo P de Almeida, Anna Vlasova, Filip Nemčko, Alexander Schleiffer, Katharina Bergauer, Lorena Hofbauer, Martina Rath, Alexander Stark
Systematic identification and characterization of repressive domains in Drosophila transcription factors. The EMBO journal (2022)
Melanie Panarotto, Iain Finley Davidson, Gabriele Litos, Alexander Schleiffer, Jan-Michael Peters
Cornelia de Lange syndrome mutations in NIPBL can impair cohesin-mediated DNA loop extrusion. Proceedings of the National Academy of Sciences of the United States of America 119 (18) (2022)
Melanie de Almeida, Matthias Hinterndorfer, Hanna Brunner, Irina Grishkovskaya, Kashish Singh, Alexander Schleiffer, Julian Jude, Sumit Deswal, Robert Kalis, Milica Vunjak, Thomas Lendl, Richard Imre, Elisabeth Roitinger, Tobias Neumann, Susanne Kandolf, Michael Schutzbier, Karl Mechtler, Gijs A Versteeg, David Haselbach, Johannes Zuber
AKIRIN2 controls the nuclear import of proteasomes in vertebrates. Nature 599 (7885) (2021)
Daniel B Grabarczyk, Olga A Petrova, Luiza Deszcz, Robert Kurzbauer, Paul Murphy, Juraj Ahel, Antonia Vogel, Rebeca Gogova, Victoria Faas, Darja Kordic, Alexander Schleiffer, Anton Meinhart, Richard Imre, Anita Lehner, Jana Neuhold, Gerd Bader, Peggy Stolt-Bergner, Jark Böttcher, Bernhard Wolkerstorfer, Gerhard Fischer, Irina Grishkovskaya, David Haselbach, Dirk Kessler, Tim Clausen
HUWE1 employs a giant substrate-binding ring to feed and regulate its HECT E3 domain. Nature chemical biology 17 (10) (2021)
Lilian M Fennell, Carlos Gomez-Diaz, Luiza Deszcz, Anoop Kavirayani, David Hoffmann, Kota Yanagitani, Alexander Schleiffer, Karl Mechtler, Astrid Hagelkruys, Josef M Penninger, Fumiyo Ikeda
Site-specific ubiquitination of the E3 ligase HOIP regulates apoptosis and immune signaling. The EMBO journal 39 (24) (2020)
Anastasiia Bondarieva, Kavya Raveendran, Vladyslav Telychko, H B D Prasada Rao, Ramya Ravindranathan, Chrysoula Zorzompokou, Friederike Finsterbusch, Ihsan Dereli, Frantzeskos Papanikos, Daniel Tränkner, Alexander Schleiffer, Ji-Feng Fei, Anna Klimova, Masaru Ito, Dhananjaya S Kulkarni, Ingo Roeder, Neil Hunter, Attila Tóth
Proline-rich protein PRR19 functions with cyclin-like CNTD1 to promote meiotic crossing over in mouse. Nature communications 11 (1) (2020)
Lukas Leiendecker, Pauline S Jung, Izabela Krecioch, Tobias Neumann, Alexander Schleiffer, Karl Mechtler, Thomas Wiesner, Anna C Obenauf
LSD1 inhibition induces differentiation and cell death in Merkel cell carcinoma. EMBO molecular medicine 12 (11) (2020)
Paola H Pinto, Alena Kroupova, Alexander Schleiffer, Karl Mechtler, Martin Jinek, Stefan Weitzer, Javier Martinez
ANGEL2 is a member of the CCR4 family of deadenylases with 2',3'-cyclic phosphatase activity. Science (New York, N.Y.) 369 (6503) (2020)
Georg Michlits, Julian Jude, Matthias Hinterndorfer, Melanie de Almeida, Gintautas Vainorius, Maria Hubmann, Tobias Neumann, Alexander Schleiffer, Thomas Rainer Burkard, Michaela Fellner, Max Gijsbertsen, Anna Traunbauer, Johannes Zuber, Ulrich Elling
Multilayered VBC score predicts sgRNAs that efficiently generate loss-of-function alleles. Nature methods 17 (7) (2020)
Oliver Schmidt, Yannick Weyer, Verena Baumann, Michael A Widerin, Sebastian Eising, Mihaela Angelova, Alexander Schleiffer, Leopold Kremser, Herbert Lindner, Matthias Peter, Florian Fröhlich, David Teis
Endosome and Golgi-associated degradation (EGAD) of membrane proteins regulates sphingolipid metabolism. The EMBO journal 38 (15) (2019)
Sarah Herberg, Krista R B Gert, Alexander Schleiffer, Andrea Pauli
The Ly6/uPAR protein Bouncer is necessary and sufficient for species-specific fertilization. Science (New York, N.Y.) 361 (6406) (2018)
Tomoko Asaoka, Jorge Almagro, Christine Ehrhardt, Isabella Tsai, Alexander Schleiffer, Luiza Deszcz, Sini Junttila, Leonie Ringrose, Karl Mechtler, Anoop Kavirayani, Attila Gyenesei, Kay Hofmann, Peter Duchek, Katrin Rittinger, Fumiyo Ikeda
Linear ubiquitination by LUBEL has a role in Drosophila heat stress response. EMBO reports 17 (11) (2016)