Tobias Engel Ayer Botrel (Tobias Engel)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 32

Top Venues

Epilepsia

International journal of molecular sciences

Cells

The Journal of neuroscience : the official journal of the Society for Neuroscience

Universidad Autonoma de Madrid Facultad de Ciencias (PHD)

This page only lists publications with an associated author ORCID identifier.

Education History

Universidad Autonoma de Madrid Facultad de Ciencias Feb 01 2002 - Sep 26 2005

Spain

PHD

Publications

Divyeshz Thakku Sivakumar, Krishi Jain, Noura Alfehaid, Yitao Wang, Xinchen Teng, Wolfgang Fischer, Tobias Engel Ayer Botrel
The Purinergic P2X7 Receptor as a Target for Adjunctive Treatment for Drug-Refractory Epilepsy. International journal of molecular sciences 25 (13) (2024)
Divyeshz Thakku Sivakumar, Krishi Jain, Noura Alfehaid, Yitao Wang, Xinchen Teng, Wolfgang Fischer, Tobias Engel Ayer Botrel
The Purinergic P2X7 Receptor as a Target for Adjunctive Treatment for Drug-Refractory Epilepsy. International journal of molecular sciences 25 (13) (2024)
Mona Heiland, Niamh M C Connolly, Omar Mamad, Ngoc T Nguyen, Jaideep C Kesavan, Elena Langa, Kevin Fanning, Albert Sanfeliu, Yan Yan, Junyi Su, Morten T Venø, Lara S Costard, Valentin Neubert, Tobias Engel Ayer Botrel, Thomas D M Hill, Thomas M Freiman, Arun Mahesh, Vijay K Tiwari, Felix Rosenow, Sebastian Bauer, Jørgen Kjems, Gareth Morris, David C Henshall
MicroRNA-335-5p suppresses voltage-gated sodium channel expression and may be a target for seizure control. Proceedings of the National Academy of Sciences of the United States of America 120 (30) (2023)
Tobias Engel Ayer Botrel
The P2X7 Receptor as a Mechanistic Biomarker for Epilepsy. International journal of molecular sciences 24 (6) (2023)
Tobias Engel Ayer Botrel
The P2X7 Receptor as a Mechanistic Biomarker for Epilepsy. International journal of molecular sciences 24 (6) (2023)
Tobias Engel Ayer Botrel
The P2X7 Receptor as a Mechanistic Biomarker for Epilepsy. International journal of molecular sciences 24 (6) (2023)
Laura de Diego-Garcia, Gary P Brennan, Theresa Auer, Aida Menendez-Mendez, Alberto Parras, Alba Martin-Gil, Meghma Mitra, Ivana Ollà, Leticia Villalba-Benito, Beatriz Gil, Mariana Alves, Kelvin Lau, Norman Delanty, Alan Beausang, Jane Cryan, Francesca M Brett, Michael A Farrell, Donncha F O'Brien, Raúl Mendez, Gonzalo Carracedo-Rodríguez, David C Henshall, José J Lucas, Tobias Engel Ayer Botrel
CPEB4 - CLOCK crosstalk during temporal lobe epilepsy. Epilepsia (2023)
Beatriz Gil, Jonathon Smith, Yong Tang, Peter Illes, Tobias Engel Ayer Botrel
Beyond Seizure Control: Treating Comorbidities in Epilepsy via Targeting of the P2X7 Receptor. International journal of molecular sciences 23 (4) (2022)
James Morgan, Oscar Moreno, Mariana Alves, Zuriñe Baz, Aida Menéndez Méndez, Hanna Leister, Ciara Melia, Jonathon Smith, Alexander Visekruna, Annette Nicke, Anindya Bhattacharya, Marc Ceusters, David C Henshall, Vanessa Gómez-Vallejo, Jordi Llop, Tobias Engel Ayer Botrel
Increased uptake of the P2X7 receptor radiotracer 18 F-JNJ-64413739 in the brain and peripheral organs according to the severity of status epilepticus in male mice. Epilepsia 64 (2) (2022)
Tobias Engel Ayer Botrel, Eva María Jiménez-Mateos, Miguel Diaz-Hernandez
Purinergic Signalling and Inflammation-Related Diseases. Cells 11 (23) (2022)
Tobias Engel Ayer Botrel, Eva María Jiménez-Mateos, Miguel Diaz-Hernandez
Purinergic Signalling and Inflammation-Related Diseases. Cells 11 (23) (2022)
James Morgan, Oscar Moreno, Mariana Alves, Zuriñe Baz, Aida Menéndez Méndez, Hanna Leister, Ciara Melia, Jonathon Smith, Alexander Visekruna, Annette Nicke, Anindya Bhattacharya, Marc Ceusters, David C Henshall, Vanessa Gómez-Vallejo, Jordi Llop, Tobias Engel Ayer Botrel
Increased uptake of the P2X7 receptor radiotracer 18 F-JNJ-64413739 in the brain and peripheral organs according to the severity of status epilepticus in male mice. Epilepsia 64 (2) (2022)
James Morgan, Oscar Moreno, Mariana Alves, Zuriñe Baz, Aida Menéndez Méndez, Hanna Leister, Ciara Melia, Jonathon Smith, Alexander Visekruna, Annette Nicke, Anindya Bhattacharya, Marc Ceusters, David C Henshall, Vanessa Gómez-Vallejo, Jordi Llop, Tobias Engel Ayer Botrel
Increased uptake of the P2X7 receptor radiotracer 18 F-JNJ-64413739 in the brain and peripheral organs according to the severity of status epilepticus in male mice. Epilepsia (2022)
James Morgan, Oscar Moreno, Mariana Alves, Zuriñe Baz, Aida Menéndez Méndez, Hanna Leister, Ciara Melia, Jonathon Smith, Alexander Visekruna, Annette Nicke, Anindya Bhattacharya, Marc Ceusters, David C Henshall, Vanessa Gómez-Vallejo, Jordi Llop, Tobias Engel Ayer Botrel
Increased uptake of the P2X7 receptor radiotracer 18 F-JNJ-64413739 in the brain and peripheral organs according to the severity of status epilepticus in male mice. Epilepsia 64 (2) (2022)
Tobias Engel Ayer Botrel, Eva María Jiménez-Mateos, Miguel Diaz-Hernandez
Purinergic Signalling and Inflammation-Related Diseases. Cells 11 (23) (2022)
James Morgan, Oscar Moreno, Mariana Alves, Zuriñe Baz, Aida Menéndez Méndez, Hanna Leister, Ciara Melia, Jonathon Smith, Alexander Visekruna, Annette Nicke, Anindya Bhattacharya, Marc Ceusters, David C Henshall, Vanessa Gómez-Vallejo, Jordi Llop, Tobias Engel Ayer Botrel
Increased uptake of the P2X7 receptor radiotracer 18 F-JNJ-64413739 in the brain and peripheral organs according to the severity of status epilepticus in male mice. Epilepsia 64 (2) (2022)
Tobias Engel Ayer Botrel, Eva María Jiménez-Mateos, Miguel Diaz-Hernandez
Purinergic Signalling and Inflammation-Related Diseases. Cells 11 (23) (2022)
James Morgan, Oscar Moreno, Mariana Alves, Zuriñe Baz, Aida Menéndez Méndez, Hanna Leister, Ciara Melia, Jonathon Smith, Alexander Visekruna, Annette Nicke, Anindya Bhattacharya, Marc Ceusters, David C Henshall, Vanessa Gómez-Vallejo, Jordi Llop, Tobias Engel Ayer Botrel
Increased uptake of the P2X7 receptor radiotracer 18 F-JNJ-64413739 in the brain and peripheral organs according to the severity of status epilepticus in male mice. Epilepsia (2022)
Edward Beamer, James Morgan, Mariana Alves, Aida Menéndez Méndez, Gareth Morris, Béla Zimmer, Giorgia Conte, Laura de Diego-Garcia, Cristina Alarcón-Vila, Nico Ka Yiu Ng, Stephen Madden, Francesco Calzaferri, Cristóbal de Los Ríos, Antonio G García, Michael Hamacher, Klaus Dinkel, Pablo Pelegrin, David C Henshall, Annette Nicke, Tobias Engel Ayer Botrel
Increased expression of the ATP-gated P2X7 receptor reduces responsiveness to anti-convulsants during status epilepticus in mice. British journal of pharmacology 179 (12) (2022)
Iago Méndez-López, Francisco J Sancho-Bielsa, Tobias Engel Ayer Botrel, Antonio G García, Juan Fernando Padín
Progressive Mitochondrial SOD1G93A Accumulation Causes Severe Structural, Metabolic and Functional Aberrations through OPA1 Down-Regulation in a Mouse Model of Amyotrophic Lateral Sclerosis. International journal of molecular sciences 22 (15) (2021)
Wenjing Ren, Patrizia Rubini, Yong Tang, Tobias Engel Ayer Botrel, Peter Illes
Inherent P2X7 Receptors Regulate Macrophage Functions during Inflammatory Diseases. International journal of molecular sciences 23 (1) (2021)
Silvia Prades, Gregory Heard, Jonathan E Gale, Tobias Engel Ayer Botrel, Robin Kopp, Annette Nicke, Katie E Smith, Daniel J Jagger
Functional P2X7 Receptors in the Auditory Nerve of Hearing Rodents Localize Exclusively to Peripheral Glia. The Journal of neuroscience : the official journal of the Society for Neuroscience 41 (12) (2021)
Edward Beamer, Austin Lacey, Mariana Alves, Giorgia Conte, Faming Tian, Laura de Diego-Garcia, Mohamed Khalil, Felix Rosenow, Norman Delanty, Nicholas Dale, Hany El-Naggar, David C Henshall, Tobias Engel Ayer Botrel
Elevated blood purine levels as a biomarker of seizures and epilepsy. Epilepsia 62 (3) (2021)
Giorgia Conte, Aida Menéndez-Méndez, Sebastian Bauer, Hany El Naggar, Mariana Alves, Annette Nicke, Norman Delanty, Felix Rosenow, David C Henshall, Tobias Engel Ayer Botrel
Circulating P2X7 Receptor Signaling Components as Diagnostic Biomarkers for Temporal Lobe Epilepsy. Cells 10 (9) (2021)
Tobias Engel Ayer Botrel, Jonathon Smith, Mariana Carlos-Alves
Targeting Neuroinflammation via Purinergic P2 Receptors for Disease Modification in Drug-Refractory Epilepsy. Journal of inflammation research 14 (2021)
Tobias Engel Ayer Botrel, Márcia Datz Abadi, Laura Chabrol Haas, Cássia Rita Pereira da Veiga, Dominihemberg de Vasconcelos Ferreira, Denis Leonardo Fontes Jardim
Pembrolizumab plus axitinib and nivolumab plus ipilimumab as first-line treatments of advanced intermediate- or poor-risk renal-cell carcinoma: a number needed to treat analysis from the Brazilian private perspective. Journal of medical economics 24 (1) (2021)
Giorgia Conte, Alberto Parras, Mariana Alves, Ivana Ollà, Laura De Diego-Garcia, Edward Beamer, Razi Alalqam, Alejandro Ocampo, Raúl Mendez, David C Henshall, José J Lucas, Tobias Engel Ayer Botrel
High concordance between hippocampal transcriptome of the mouse intra-amygdala kainic acid model and human temporal lobe epilepsy. Epilepsia 61 (12) (2020)
Aida Menéndez Méndez, Jonathon Smith, Tobias Engel Ayer Botrel
Neonatal Seizures and Purinergic Signalling. International journal of molecular sciences 21 (21) (2020)
James Morgan, Mariana Carlos-Alves, Giorgia Conte, Aida Menéndez-Méndez, Laura de Diego-Garcia, Gioacchino de Leo, Edward Beamer, Jonathon Smith, Annette Nicke, Tobias Engel Ayer Botrel
Characterization of the Expression of the ATP-Gated P2X7 Receptor Following Status Epilepticus and during Epilepsy Using a P2X7-EGFP Reporter Mouse. Neuroscience bulletin 36 (11) (2020)
Mariana Alves, Laura De Diego Garcia, Giorgia Conte, Eva M Jimenez-Mateos, Beatrice D'Orsi, Amaya Sanz-Rodriguez, Jochen H M Prehn, David C Henshall, Tobias Engel Ayer Botrel
Context-Specific Switch from Anti- to Pro-epileptogenic Function of the P2Y1 Receptor in Experimental Epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience 39 (27) (2019)
Vamshidhar R Vangoor, Cristina R Reschke, Ketharini Senthilkumar, Lieke L van de Haar, Marina de Wit, Giuliano Giuliani, Mark H Broekhoven, Gareth Morris, Tobias Engel Ayer Botrel, Gary P Brennan, Ronan M Conroy, Peter C van Rijen, Peter H Gosselaar, Stephanie Schorge, Roel Q J Schaapveld, David C Henshall, Pierre N E De Graan, Ronald Jeroen Pasterkamp
Antagonizing Increased miR-135a Levels at the Chronic Stage of Experimental TLE Reduces Spontaneous Recurrent Seizures. The Journal of neuroscience : the official journal of the Society for Neuroscience 39 (26) (2019)
Aidan Kenny, Hazel McArdle, Miguel Calero Lara, Alberto Rabano, Stephen F Madden, Kellie Adamson, Robert Forster, Elaine Spain, Jochen H M Prehn, David C Henshall, Miguel Medina Padilla, Eva M Jimenez-Mateos, Tobias Engel Ayer Botrel
Elevated Plasma microRNA-206 Levels Predict Cognitive Decline and Progression to Dementia from Mild Cognitive Impairment. Biomolecules 9 (11) (2019)

Tobias Engel Ayer Botrel.css-eqlu8i{font-size:small;padding-left:4px;} (Tobias Engel)

Publication Activity (10 Years)

Top Topics

Top Venues

Tobias Engel Ayer Botrel (Tobias Engel)