Pablo Pelegrin (Pablo Pelegrín)

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 34

Top Topics

Nlrp Inflammasome

Top Venues

Nature communications

Cell death discovery

International journal of molecular sciences

This page only lists publications with an associated author ORCID identifier.

Publications

Cristina Molina-López, Laura Hurtado-Navarro, Carlos J García, Diego Angosto-Bazarra, Fernando Vallejo, Ana Tapia-Abellán, Joana R Marques-Soares, Carmen Vargas, Segundo Bujan-Rivas, Francisco Abraham Tomás-Barberán, Juan Ignacio Aróstegui, Pablo Pelegrin
Pathogenic NLRP3 mutants form constitutively active inflammasomes resulting in immune-metabolic limitation of IL-1β production. Nature communications 15 (1) (2024)
Sandra V Mateo, Daniel Vidal-Correoso, Ana M Muñoz-Morales, Marta Jover-Aguilar, Felipe Alconchel, Jesús de la Peña, Laura Martínez-Alarcón, Víctor López-López, Antonio Ríos-Zambudio, Pedro Cascales, José A Pons, Pablo Ramírez, Pablo Pelegrin, Alberto Baroja-Mazo
Detection of inflammasome activation in liver tissue during the donation process as potential biomarker for liver transplantation. Cell death discovery 10 (1) (2024)
Sandra V Mateo, Daniel Vidal-Correoso, Ana M Muñoz-Morales, Marta Jover-Aguilar, Felipe Alconchel, Jesús de la Peña, Laura Martínez-Alarcón, Víctor López-López, Antonio Ríos-Zambudio, Pedro Cascales, José A Pons, Pablo Ramírez, Pablo Pelegrin, Alberto Baroja-Mazo
Detection of inflammasome activation in liver tissue during the donation process as potential biomarker for liver transplantation. Cell death discovery 10 (1) (2024)
Sandra V Mateo, Daniel Vidal-Correoso, Ana M Muñoz-Morales, Marta Jover-Aguilar, Felipe Alconchel, Jesús de la Peña, Laura Martínez-Alarcón, Víctor López-López, Antonio Ríos-Zambudio, Pedro Cascales, José A Pons, Pablo Ramírez, Pablo Pelegrin, Alberto Baroja-Mazo
Detection of inflammasome activation in liver tissue during the donation process as potential biomarker for liver transplantation. Cell death discovery 10 (1) (2024)
Cristina Molina-López, Laura Hurtado-Navarro, Carlos J García, Diego Angosto-Bazarra, Fernando Vallejo, Ana Tapia-Abellán, Joana R Marques-Soares, Carmen Vargas, Segundo Bujan-Rivas, Francisco Abraham Tomás-Barberán, Juan Ignacio Aróstegui, Pablo Pelegrin
Pathogenic NLRP3 mutants form constitutively active inflammasomes resulting in immune-metabolic limitation of IL-1β production. Nature communications 15 (1) (2024)
Cristina Molina-López, Laura Hurtado-Navarro, Carlos J García, Diego Angosto-Bazarra, Fernando Vallejo, Ana Tapia-Abellán, Joana R Marques-Soares, Carmen Vargas, Segundo Bujan-Rivas, Francisco Abraham Tomás-Barberán, Juan Ignacio Aróstegui, Pablo Pelegrin
Pathogenic NLRP3 mutants form constitutively active inflammasomes resulting in immune-metabolic limitation of IL-1β production. Nature communications 15 (1) (2024)
Marisol Villalva, Juan José Martínez-García, Laura Jaime, Susana Santoyo, Pablo Pelegrin, Jara Perez-Jimenez
Polyphenols as NLRP3 inflammasome modulators in cardiometabolic diseases: a review of in vivo studies. Food & function (2023)
Fatima Martin-Sanchez, Vincent Compan, Alejandro Peñín-Franch, Ana Tapia-Abellán, Ana I Gómez, María C Baños-Gregori, Florian Ingo Schmidt, Pablo Pelegrin
ASC oligomer favors caspase-1CARD domain recruitment after intracellular potassium efflux. The Journal of cell biology 222 (8) (2023)
Iván Hernández-Caravaca, Carla Moros-Nicolás, Leopoldo González-Brusi, Mª José Romero de Ávila, Catalina De Paco Matallana, Pablo Pelegrin, María Ángeles Castaño-Molina, Lucía Díaz-Meca, Javier Sánchez-Romero, Laura Martínez-Alarcón, Manuel Avilés, Mª José Izquierdo-Rico
Colostrum Features of Active and Recovered COVID-19 Patients Revealed Using Next-Generation Proteomics Technique, SWATH-MS. Children (Basel, Switzerland) 10 (8) (2023)
Alejandro Peñín-Franch, José Antonio García-Vidal, Carlos Manuel Martínez, Pilar Escolar-Reina, Rosa M Martínez-Ojeda, Ana I Gómez, Juan M Bueno, Francisco Minaya-Muñoz, Fermín Valera-Garrido, Francesc Medina-Mirapeix, Pablo Pelegrin
Galvanic current activates the NLRP3 inflammasome to promote Type I collagen production in tendon. eLife 11 (2022)
Sahil Adriouch, Pablo Pelegrin
ASC nanobodies to counteract the consequences of inflammasome activation. EMBO molecular medicine 14 (6) (2022)
Laura Hurtado-Navarro, Diego Angosto-Bazarra, Pablo Pelegrin, Alberto Baroja-Mazo, Santiago Cuevas
NLRP3 Inflammasome and Pyroptosis in Liver Pathophysiology: The Emerging Relevance of Nrf2 Inducers. Antioxidants (Basel, Switzerland) 11 (5) (2022)
Diego Angosto-Bazarra, Cristina Alarcón-Vila, Laura Hurtado-Navarro, María C Baños, Jack Rivers-Auty, Pablo Pelegrin
Evolutionary analyses of the gasdermin family suggest conserved roles in infection response despite loss of pore-forming functionality. BMC biology 20 (1) (2022)
Fernando Lucas-Ruiz, Alejandro Peñín-Franch, José Antonio Pons, Pablo Ramírez, Pablo Pelegrin, Santiago Cuevas, Alberto Baroja-Mazo
Emerging Role of NLRP3 Inflammasome and Pyroptosis in Liver Transplantation. International journal of molecular sciences 23 (22) (2022)
Edward Beamer, James Morgan, Mariana Alves, Aida Menéndez Méndez, Gareth Morris, Béla Zimmer, Giorgia Conte, Laura de Diego-Garcia, Cristina Alarcón-Vila, Nico Ka Yiu Ng, Stephen Madden, Francesco Calzaferri, Cristóbal de Los Ríos, Antonio G García, Michael Hamacher, Klaus Dinkel, Pablo Pelegrin, David C Henshall, Annette Nicke, Tobias Engel Ayer Botrel
Increased expression of the ATP-gated P2X7 receptor reduces responsiveness to anti-convulsants during status epilepticus in mice. British journal of pharmacology 179 (12) (2022)
Diego Angosto-Bazarra, Cristina Molina-López, Pablo Pelegrin
Physiological and pathophysiological functions of NLRP6: pro- and anti-inflammatory roles. Communications biology 5 (1) (2022)
Carlos de Torre-Minguela, Ana I Gómez, Isabelle Couillin, Pablo Pelegrin
Gasdermins mediate cellular release of mitochondrial DNA during pyroptosis and apoptosis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 35 (8) (2021)
Paula M Soriano-Teruel, Guillermo García-Laínez, María Marco-Salvador, Julian Pardo, Maykel Arias, Christian DeFord, Irmgard Merfort, María J Vicent, Pablo Pelegrin, Mónica Sancho, Mar Orzáez
Identification of an ASC oligomerization inhibitor for the treatment of inflammatory diseases. Cell death & disease 12 (12) (2021)
Ana Tapia-Abellán, Diego Angosto-Bazarra, Cristina Alarcón-Vila, María C Baños, Iva Hafner Bratkovič, Baldomero Oliva Miguel, Pablo Pelegrin
Sensing low intracellular potassium by NLRP3 results in a stable open structure that promotes inflammasome activation. Science advances 7 (38) (2021)
Diego Angosto-Bazarra, Cristina Molina-López, Alejandro Peñín-Franch, Laura Hurtado-Navarro, Pablo Pelegrin
Techniques to Study Inflammasome Activation and Inhibition by Small Molecules. Molecules (Basel, Switzerland) 26 (6) (2021)
Carmen De Miguel, Pablo Pelegrin, Alberto Baroja-Mazo, Santiago Cuevas
Emerging Role of the Inflammasome and Pyroptosis in Hypertension. International journal of molecular sciences 22 (3) (2021)
Daniela Ionescu, Alejandro Peñín-Franch, Anna Mensa-Vilaró, Paola Castillo, Laura Hurtado-Navarro, Cristina Molina-López, Silvia Romero-Chala, Susana Plaza, Virginia Fabregat, Segundo Buján, Joana Marques, Ferran Casals, Jordi Yagüe, Baldomero Oliva, Luis Miguel Fernández-Pereira, Pablo Pelegrin, Juan Ignacio Aróstegui
First Description of Late-Onset Autoinflammatory Disease Due to Somatic NLRC4 Mosaicism. Arthritis & rheumatology (Hoboken, N.J.) (2021)
Alberto Baroja-Mazo, Vincent Compan, Fátima Martín-Sánchez, Ana Tapia-Abellán, Isabelle Couillin, Pablo Pelegrin
Author Correction: Early endosome autoantigen 1 regulates IL-1β release upon caspase-1 activation independently of gasdermin D membrane permeabilization. Scientific reports 10 (1) (2020)
Cristina Alarcón-Vila, Alberto Baroja-Mazo, Carlos de Torre-Minguela, Carlos Manuel Martínez, Juan J Martínez-García, Helios Martínez-Banaclocha, Carlos García-Palenciano, Pablo Pelegrin
CD14 release induced by P2X7 receptor restricts inflammation and increases survival during sepsis. eLife 9 (2020)
Gonzalo de la Rosa, Ana I Gómez, María C Baños, Pablo Pelegrin
Signaling Through Purinergic Receptor P2Y2 Enhances Macrophage IL-1β Production. International journal of molecular sciences 21 (13) (2020)
Juan José Martínez-García, Helios Martínez-Banaclocha, Diego Angosto-Bazarra, Carlos de Torre-Minguela, Alberto Baroja-Mazo, Cristina Alarcón-Vila, Laura Martínez-Alarcón, Joaquín Amores-Iniesta, Fátima Martín-Sánchez, Giovanni A Ercole, Carlos Manuel Martínez, Ada González-Lisorge, José Fernández-Pacheco, Piedad Martínez-Gil, Sahil Adriouch, Friedrich Koch-Nolte, Juan Luján, Francisco Acosta-Villegas, Pascual Parrilla, Carlos García-Palenciano, Pablo Pelegrin
P2X7 receptor induces mitochondrial failure in monocytes and compromises NLRP3 inflammasome activation during sepsis. Nature communications 10 (1) (2019)
Ana Tapia-Abellán, Diego Angosto-Bazarra, Helios Martínez-Banaclocha, Carlos de Torre-Minguela, Jose P Cerón-Carrasco, Horacio Pérez-Sánchez, Juan I Arostegui, Pablo Pelegrin
MCC950 closes the active conformation of NLRP3 to an inactive state. Nature chemical biology 15 (6) (2019)
Petr Broz, Pablo Pelegrin, Feng Shao
The gasdermins, a protein family executing cell death and inflammation. Nature reviews. Immunology 20 (3) (2019)
Alberto Baroja-Mazo, Vincent Compan, Fátima Martín-Sánchez, Ana Tapia-Abellán, Isabelle Couillin, Pablo Pelegrin
Early endosome autoantigen 1 regulates IL-1β release upon caspase-1 activation independently of gasdermin D membrane permeabilization. Scientific reports 9 (1) (2019)
Iva Hafner Bratkovič, Petra Sušjan, Duško Lainšček, Ana Tapia-Abellán, Kosta Cerović, Lucija Kadunc, Diego Angosto-Bazarra, Pablo Pelegrin, Roman Jerala
NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome pathway. Nature communications 9 (1) (2018)
Pablo Pelegrin
Reprogramming macrophages by plasmin. Blood 129 (21) (2018)
Chiara Parisi, Giulia Napoli, Pablo Pelegrin, Cinzia Volonté
M1 and M2 Functional Imprinting of Primary Microglia: Role of P2X7 Activation and miR-125b. Mediators of inflammation 2016 (2016)
Gema Lordén, Itziar Sanjuán-García, Nagore de Pablo, Clara Meana, Inés Alvarez-Miguel, María Teresa Pérez-García, Pablo Pelegrin, Jesús Balsinde, María A Balboa
Lipin-2 regulates NLRP3 inflammasome by affecting P2X7 receptor activation. The Journal of experimental medicine 214 (2) (2016)
Emeline Bon, Virginie Driffort, Frédéric Gradek, Carlos Martinez-Caceres, Monique Anchelin, Pablo Pelegrin, Maria-Luisa Cayuela, Séverine Marionneau-Lambot, Thibauld Oullier, Roseline Guibon, Gaëlle Fromont, Jorge L Gutierrez-Pajares, Isabelle Domingo, Eric Piver, Alain Moreau, Julien Burlaud-Gaillard, Philippe G Frank, Stéphan Chevalier, Pierre Besson, Sébastien Roger
SCN4B acts as a metastasis-suppressor gene preventing hyperactivation of cell migration in breast cancer. Nature communications 7 (2016)
Alberto Baroja-Mazo, Fatima Martín-Sánchez, Ana I Gomez, Carlos M Martínez, Joaquín Amores-Iniesta, Vincent Compan, Maria Barberà-Cremades, Jordi Yagüe, Estibaliz Ruiz-Ortiz, Jordi Antón, Segundo Buján, Isabelle Couillin, David Brough, Juan I Arostegui, Pablo Pelegrin
The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response. Nature immunology 15 (8) (2014)
Vincent Compan, Fátima Martín-Sánchez, Alberto Baroja-Mazo, Gloria López-Castejón, Ana I Gomez, Alexei Verkhratsky, David Brough, Pablo Pelegrin
Apoptosis-associated speck-like protein containing a CARD forms specks but does not activate caspase-1 in the absence of NLRP3 during macrophage swelling. Journal of immunology (Baltimore, Md. : 1950) 194 (3) (2014)