Willem A L van Otterlo

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 14

Top Topics

Toxoplasma Gondii

Cell Cycle Arrest

Top Venues

Journal of medicinal chemistry

Beilstein journal of organic chemistry

ACS infectious diseases

This page only lists publications with an associated author ORCID identifier.

Publications

Sachin B Wagh, Dino Berthold, Iram Majeed, L Kevin Lewis, David Schilter, Birgit Mertens, Antonio Evidente, Willem A L van Otterlo, Véronique Mathieu, Alexander Kornienko
Sphaeropsidin A C15-C16 Cross-Metathesis Analogues with Potent Anticancer Activity. ChemMedChem (2024)
Aletta E van der Westhuyzen, Naghmana Ashraf, Daleen Conradie, Leigh Loots, Catherine H Kaschula, Stephen C Pelly, Liliya V Frolova, Taylor Landfair, Charles B Shuster, Tania Betancourt, Alexander Kornienko, Willem A L van Otterlo
Improved Rigidin-Inspired Antiproliferative Agents with Modifications on the 7-Deazahypoxanthine C7/C8 Ring Systems. Journal of medicinal chemistry (2024)
Aletta E van der Westhuyzen, Naghmana Ashraf, Daleen Conradie, Leigh Loots, Catherine H Kaschula, Stephen C Pelly, Liliya V Frolova, Taylor Landfair, Charles B Shuster, Tania Betancourt, Alexander Kornienko, Willem A L van Otterlo
Improved Rigidin-Inspired Antiproliferative Agents with Modifications on the 7-Deazahypoxanthine C7/C8 Ring Systems. Journal of medicinal chemistry 67 (12) (2024)
Aletta E van der Westhuyzen, Naghmana Ashraf, Daleen Conradie, Leigh Loots, Catherine H Kaschula, Stephen C Pelly, Liliya V Frolova, Taylor Landfair, Charles B Shuster, Tania Betancourt, Alexander Kornienko, Willem A L van Otterlo
Improved Rigidin-Inspired Antiproliferative Agents with Modifications on the 7-Deazahypoxanthine C7/C8 Ring Systems. Journal of medicinal chemistry 67 (12) (2024)
Aletta E van der Westhuyzen, Naghmana Ashraf, Daleen Conradie, Leigh Loots, Catherine H Kaschula, Stephen C Pelly, Liliya V Frolova, Taylor Landfair, Charles B Shuster, Tania Betancourt, Alexander Kornienko, Willem A L van Otterlo
Improved Rigidin-Inspired Antiproliferative Agents with Modifications on the 7-Deazahypoxanthine C7/C8 Ring Systems. Journal of medicinal chemistry 67 (12) (2024)
Aletta E van der Westhuyzen, Naghmana Ashraf, Daleen Conradie, Leigh Loots, Catherine H Kaschula, Stephen C Pelly, Liliya V Frolova, Taylor Landfair, Charles B Shuster, Tania Betancourt, Alexander Kornienko, Willem A L van Otterlo
Improved Rigidin-Inspired Antiproliferative Agents with Modifications on the 7-Deazahypoxanthine C7/C8 Ring Systems. Journal of medicinal chemistry 67 (12) (2024)
Akash Sabarwal, Jaco C van Rooyen, Jeremy Caburet, Moscos Avgenikos, Arpit Dheeraj, Mansoor Ali, Deepali Mishra, Joséphine S B de Meester, Saskia Stander, Willem A L van Otterlo, Catherine H Kaschula, Rana P Singh
A novel 4'-brominated derivative of fisetin induces cell cycle arrest and apoptosis and inhibits EGFR/ERK1/2/STAT3 pathways in non-small-cell lung cancer without any adverse effects in mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 36 (12) (2022)
Alet E van der Westhuyzen, Aude Ingels, Rémi Rosière, Karim Amighi, Lukas Oberer, Kirk R Gustafson, Dongdong Wang, Antonio Evidente, Lucia Maddau, Marco Masi, André de Villiers, Ivan R Green, Walter Berger, Alexander Kornienko, Veronique Mathieu, Willem A L van Otterlo
Deciphering the chemical instability of sphaeropsidin A under physiological conditions - degradation studies and structural elucidation of the major metabolite. Organic & biomolecular chemistry 18 (40) (2022)
Robin Klintworth, Garreth L Morgans, Stefania M Scalzullo, Charles B de Koning, Willem A L van Otterlo, Joseph P Michael
Silica gel and microwave-promoted synthesis of dihydropyrrolizines and tetrahydroindolizines from enaminones. Beilstein journal of organic chemistry 17 (2021)
Jonas Lategahn, Julia Hardick, Tobias Grabe, Janina Niggenaber, Kirujan Jeyakumar, Marina Keul, Hannah L Tumbrink, Christian Becker, Luke Hodson, Tonia Kirschner, Philip Klövekorn, Julia Ketzer, Matthias Baumann, Susanne Terheyden, Anke Unger, Jörn Weisner, Matthias Philipp Müller, Willem A L van Otterlo, Sebastian Bauer, Daniel Rauh
Targeting Her2-insYVMA with Covalent Inhibitors-A Focused Compound Screening and Structure-Based Design Approach. Journal of medicinal chemistry 63 (20) (2020)
Maria Letizia Ciavatta, Florence Lefranc, Leandro M Vieira, Robert Kiss, Marianna Carbone, Willem A L van Otterlo, Nicole B Lopanik, Andrea Waeschenbach
The Phylum Bryozoa: From Biology to Biomedical Potential. Marine drugs 18 (4) (2020)
Riyad Domingo, Renier van der Westhuyzen, Anton R Hamann, Konrad J Mostert, Leanne Barnard, Tanya Paquet, Erick T Tjhin, Kevin J Saliba, Willem A L van Otterlo, Erick Strauss
Overcoming synthetic challenges in targeting coenzyme A biosynthesis with the antimicrobial natural product CJ-15,801. MedChemComm 10 (12) (2019)
Myron M Johnson, Jeremy M Naidoo, Manuel A Fernandes, Edwin M Mmutlane, Willem A L van Otterlo, Charles B de Koning
Correction to CAN-Mediated Oxidations for the Synthesis of Xanthones and Related Products. The Journal of organic chemistry 84 (1) (2018)
Leanne Barnard, Konrad J Mostert, Willem A L van Otterlo, Erick Strauss
Developing Pantetheinase-Resistant Pantothenamide Antibacterials: Structural Modification Impacts on PanK Interaction and Mode of Action. ACS infectious diseases 4 (5) (2018)