Janina Niggenaber (J Niggenaber)

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 10

Top Topics

Advanced Non Small Cell Lung Cancer

High Resolution

Tyrosine Kinase

Capillary Electrophoresis

Top Venues

Nature communications

Journal of medicinal chemistry

ACS medicinal chemistry letters

Chemical science

This page only lists publications with an associated author ORCID identifier.

Publications

Alina Teuber, Tom Schulz, B S Fletcher, Rajesh Gontla, Thomas Mühlenberg, M-L Zischinsky, Janina Niggenaber, Jörn Weisner, S B Kleinbölting, Jonas Lategahn, Sonja Sievers, Matthias Philipp Müller, Sebastian Bauer, Daniel Rauh
Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA. Nature communications 15 (1) (2024)
Alina Teuber, Tom Schulz, B S Fletcher, Rajesh Gontla, Thomas Mühlenberg, M-L Zischinsky, Janina Niggenaber, Jörn Weisner, S B Kleinbölting, Jonas Lategahn, Sonja Sievers, Matthias Philipp Müller, Sebastian Bauer, Daniel Rauh
Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA. Nature communications 15 (1) (2024)
Alina Teuber, Tom Schulz, B S Fletcher, Rajesh Gontla, Thomas Mühlenberg, M-L Zischinsky, Janina Niggenaber, Jörn Weisner, S B Kleinbölting, Jonas Lategahn, Sonja Sievers, Matthias Philipp Müller, Sebastian Bauer, Daniel Rauh
Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA. Nature communications 15 (1) (2024)
Alina Teuber, Tom Schulz, B S Fletcher, Rajesh Gontla, Thomas Mühlenberg, M-L Zischinsky, Janina Niggenaber, Jörn Weisner, S B Kleinbölting, Jonas Lategahn, Sonja Sievers, Matthias Philipp Müller, Sebastian Bauer, Daniel Rauh
Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA. Nature communications 15 (1) (2024)
Tobias Grabe, Kirujan Jeyakumar, Janina Niggenaber, Tom Schulz, Sandra Koska, Silke Kleinbölting, Michael Edmund Beck, Matthias Philipp Müller, Daniel Rauh
Addressing the Osimertinib Resistance Mutation EGFR-L858R/C797S with Reversible Aminopyrimidines. ACS medicinal chemistry letters 14 (5) (2023)
Tobias Grabe, Kirujan Jeyakumar, Janina Niggenaber, Tom Schulz, Sandra Koska, Silke Kleinbölting, Michael Edmund Beck, Matthias Philipp Müller, Daniel Rauh
Addressing the Osimertinib Resistance Mutation EGFR-L858R/C797S with Reversible Aminopyrimidines. ACS medicinal chemistry letters 14 (5) (2023)
Jonas Lategahn, Hannah L Tumbrink, Carsten Schultz-Fademrecht, Alena Heimsoeth, Lisa Werr, Janina Niggenaber, Marina Keul, Fatma Parmaksiz, Matthias Baumann, Sascha Menninger, Eldar Zent, Ina Landel, Jörn Weisner, Kirujan Jeyakumar, Leonie Heyden, Nicole Russ, Fabienne Müller, Carina Lorenz, Johannes Brägelmann, Inga Spille, Tobias Grabe, Matthias Philipp Müller, Johannes M Heuckmann, Bert M Klebl, Peter Nussbaumer, Martin L Sos, Daniel Rauh
Insight into Targeting Exon20 Insertion Mutations of the Epidermal Growth Factor Receptor with Wild Type-Sparing Inhibitors. Journal of medicinal chemistry 65 (9) (2022)
Jonas Lategahn, Julia Hardick, Tobias Grabe, Janina Niggenaber, Kirujan Jeyakumar, Marina Keul, Hannah L Tumbrink, Christian Becker, Luke Hodson, Tonia Kirschner, Philip Klövekorn, Julia Ketzer, Matthias Baumann, Susanne Terheyden, Anke Unger, Jörn Weisner, Matthias Philipp Müller, Willem A L van Otterlo, Sebastian Bauer, Daniel Rauh
Targeting Her2-insYVMA with Covalent Inhibitors-A Focused Compound Screening and Structure-Based Design Approach. Journal of medicinal chemistry 63 (20) (2020)
Janina Niggenaber, Julia Hardick, Jonas Lategahn, Daniel Rauh
Structure Defines Function: Clinically Relevant Mutations in ErbB Kinases. Journal of medicinal chemistry 63 (1) (2019)
Jonas Lategahn, Marina Keul, Philip Klövekorn, Hannah L Tumbrink, Janina Niggenaber, Matthias Philipp Müller, Luke Hodson, Maren Flaßhoff, Julia Hardick, Tobias Grabe, Julian Engel, Carsten Schultz-Fademrecht, Matthias Baumann, Julia Ketzer, Thomas Mühlenberg, Wolf Hiller, Georgia Günther, Anke Unger, Heiko Müller, Alena Heimsoeth, Christopher Golz, Bernhard Blank-Landeshammer, Laxmikanth Kollipara, René Peiman Zahedi, Carsten Strohmann, Jan G Hengstler, Willem A L van Otterlo, Sebastian Bauer, Daniel Rauh
Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S. Chemical science 10 (46) (2019)