Jonas Lategahn (J Lategahn)

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 18

Top Venues

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Nature communications

Journal of medicinal chemistry

Scientific reports

TU Dortmund University

This page only lists publications with an associated author ORCID identifier.

Affiliation History

TU Dortmund University Mar 15 2018 - Mar 31 2019

Germany

PostDoc, Drug Discovery Hub Dortmund :: Faculty of Chemistry and Chemical Biology

Publications

Alina Teuber, Tom Schulz, B S Fletcher, Rajesh Gontla, Thomas Mühlenberg, M-L Zischinsky, Janina Niggenaber, Jörn Weisner, S B Kleinbölting, Jonas Lategahn, Sonja Sievers, Matthias Philipp Müller, Sebastian Bauer, Daniel Rauh
Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA. Nature communications 15 (1) (2024)
Thomas Mühlenberg, Johanna Falkenhorst, Tom Schulz, Benjamin S Fletcher, Alina Teuber, Dawid Krzeciesa, Isabella Klooster, Meijun Z Lundberg, Lydia Wilson, Jonas Lategahn, Margaret von Mehren, Susanne Grunewald, Alicia Isabell Tüns, Eva Wardelmann, Jason K Sicklick, Mehdi Brahmi, César Serrano, Hans-Ulrich Schildhaus, Sonja Sievers, Jürgen Treckmann, Michael C Heinrich, Chandrajit P Raut, Wen-Bin Ou, Adrian Mariño-Enriquez, Suzanne George, Daniel Rauh, Jonathan A Fletcher, Sebastian Bauer
KIT ATP-Binding Pocket/Activation Loop Mutations in GI Stromal Tumor: Emerging Mechanisms of Kinase Inhibitor Escape. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (12) (2024)
Alina Teuber, Tom Schulz, B S Fletcher, Rajesh Gontla, Thomas Mühlenberg, M-L Zischinsky, Janina Niggenaber, Jörn Weisner, S B Kleinbölting, Jonas Lategahn, Sonja Sievers, Matthias Philipp Müller, Sebastian Bauer, Daniel Rauh
Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA. Nature communications 15 (1) (2024)
Thomas Mühlenberg, Johanna Falkenhorst, Tom Schulz, Benjamin S Fletcher, Alina Teuber, Dawid Krzeciesa, Isabella Klooster, Meijun Z Lundberg, Lydia Wilson, Jonas Lategahn, Margaret von Mehren, Susanne Grunewald, Alicia Isabell Tüns, Eva Wardelmann, Jason K Sicklick, Mehdi Brahmi, César Serrano, Hans-Ulrich Schildhaus, Sonja Sievers, Jürgen Treckmann, Michael C Heinrich, Chandrajit P Raut, Wen-Bin Ou, Adrian Mariño-Enriquez, Suzanne George, Daniel Rauh, Jonathan A Fletcher, Sebastian Bauer
KIT ATP-Binding Pocket/Activation Loop Mutations in GI Stromal Tumor: Emerging Mechanisms of Kinase Inhibitor Escape. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (12) (2024)
Thomas Mühlenberg, Johanna Falkenhorst, Tom Schulz, Benjamin S Fletcher, Alina Teuber, Dawid Krzeciesa, Isabella Klooster, Meijun Z Lundberg, Lydia Wilson, Jonas Lategahn, Margaret von Mehren, Susanne Grunewald, Alicia Isabell Tüns, Eva Wardelmann, Jason K Sicklick, Mehdi Brahmi, César Serrano, Hans-Ulrich Schildhaus, Sonja Sievers, Jürgen Treckmann, Michael C Heinrich, Chandrajit P Raut, Wen-Bin Ou, Adrian Mariño-Enriquez, Suzanne George, Daniel Rauh, Jonathan A Fletcher, Sebastian Bauer
KIT ATP-Binding Pocket/Activation Loop Mutations in GI Stromal Tumor: Emerging Mechanisms of Kinase Inhibitor Escape. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (12) (2024)
Alina Teuber, Tom Schulz, B S Fletcher, Rajesh Gontla, Thomas Mühlenberg, M-L Zischinsky, Janina Niggenaber, Jörn Weisner, S B Kleinbölting, Jonas Lategahn, Sonja Sievers, Matthias Philipp Müller, Sebastian Bauer, Daniel Rauh
Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA. Nature communications 15 (1) (2024)
Alina Teuber, Tom Schulz, B S Fletcher, Rajesh Gontla, Thomas Mühlenberg, M-L Zischinsky, Janina Niggenaber, Jörn Weisner, S B Kleinbölting, Jonas Lategahn, Sonja Sievers, Matthias Philipp Müller, Sebastian Bauer, Daniel Rauh
Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA. Nature communications 15 (1) (2024)
Thomas Mühlenberg, Johanna Falkenhorst, Tom Schulz, Benjamin S Fletcher, Alina Teuber, Dawid Krzeciesa, Isabella Klooster, Meijun Z Lundberg, Lydia Wilson, Jonas Lategahn, Margaret von Mehren, Susanne Grunewald, Alicia Isabell Tüns, Eva Wardelmann, Jason K Sicklick, Mehdi Brahmi, César Serrano, Hans-Ulrich Schildhaus, Sonja Sievers, Jürgen Treckmann, Michael C Heinrich, Chandrajit P Raut, Wen-Bin Ou, Adrian Mariño-Enriquez, Suzanne George, Daniel Rauh, Jonathan A Fletcher, Sebastian Bauer
KIT ATP-Binding Pocket/Activation Loop Mutations in GI Stromal Tumor: Emerging Mechanisms of Kinase Inhibitor Escape. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (12) (2024)
Thomas Mühlenberg, Johanna Falkenhorst, Tom Schulz, Benjamin S Fletcher, Alina Teuber, Dawid Krzeciesa, Isabella Klooster, Meijun Z Lundberg, Lydia Wilson, Jonas Lategahn, Margaret von Mehren, Susanne Grunewald, Alicia Isabell Tüns, Eva Wardelmann, Jason K Sicklick, Mehdi Brahmi, César Serrano, Hans-Ulrich Schildhaus, Sonja Sievers, Jürgen Treckmann, Michael C Heinrich, Chandrajit P Raut, Wen-Bin Ou, Adrian Mariño-Enriquez, Suzanne George, Daniel Rauh, Jonathan A Fletcher, Sebastian Bauer
KIT ATP-Binding Pocket/Activation Loop Mutations in GI Stromal Tumor: Emerging Mechanisms of Kinase Inhibitor Escape. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
Thomas Mühlenberg, Johanna Falkenhorst, Tom Schulz, Benjamin S Fletcher, Alina Teuber, Dawid Krzeciesa, Isabella Klooster, Meijun Z Lundberg, Lydia Wilson, Jonas Lategahn, Margaret von Mehren, Susanne Grunewald, Alicia Isabell Tüns, Eva Wardelmann, Jason K Sicklick, Mehdi Brahmi, César Serrano, Hans-Ulrich Schildhaus, Sonja Sievers, Jürgen Treckmann, Michael C Heinrich, Chandrajit P Raut, Wen-Bin Ou, Adrian Mariño-Enriquez, Suzanne George, Daniel Rauh, Jonathan A Fletcher, Sebastian Bauer
KIT ATP-Binding Pocket/Activation Loop Mutations in GI Stromal Tumor: Emerging Mechanisms of Kinase Inhibitor Escape. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (12) (2024)
Thomas Mühlenberg, Johanna Falkenhorst, Tom Schulz, Benjamin S Fletcher, Alina Teuber, Dawid Krzeciesa, Isabella Klooster, Meijun Z Lundberg, Lydia Wilson, Jonas Lategahn, Margaret von Mehren, Susanne Grunewald, Alicia Isabell Tüns, Eva Wardelmann, Jason K Sicklick, Mehdi Brahmi, César Serrano, Hans-Ulrich Schildhaus, Sonja Sievers, Jürgen Treckmann, Michael C Heinrich, Chandrajit P Raut, Wen-Bin Ou, Adrian Mariño-Enriquez, Suzanne George, Daniel Rauh, Jonathan A Fletcher, Sebastian Bauer
KIT ATP-Binding Pocket/Activation Loop Mutations in GI Stromal Tumor: Emerging Mechanisms of Kinase Inhibitor Escape. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (12) (2024)
Jonas Lategahn, Hannah L Tumbrink, Carsten Schultz-Fademrecht, Alena Heimsoeth, Lisa Werr, Janina Niggenaber, Marina Keul, Fatma Parmaksiz, Matthias Baumann, Sascha Menninger, Eldar Zent, Ina Landel, Jörn Weisner, Kirujan Jeyakumar, Leonie Heyden, Nicole Russ, Fabienne Müller, Carina Lorenz, Johannes Brägelmann, Inga Spille, Tobias Grabe, Matthias Philipp Müller, Johannes M Heuckmann, Bert M Klebl, Peter Nussbaumer, Martin L Sos, Daniel Rauh
Insight into Targeting Exon20 Insertion Mutations of the Epidermal Growth Factor Receptor with Wild Type-Sparing Inhibitors. Journal of medicinal chemistry 65 (9) (2022)
Jonas Lategahn, Julia Hardick, Tobias Grabe, Janina Niggenaber, Kirujan Jeyakumar, Marina Keul, Hannah L Tumbrink, Christian Becker, Luke Hodson, Tonia Kirschner, Philip Klövekorn, Julia Ketzer, Matthias Baumann, Susanne Terheyden, Anke Unger, Jörn Weisner, Matthias Philipp Müller, Willem A L van Otterlo, Sebastian Bauer, Daniel Rauh
Targeting Her2-insYVMA with Covalent Inhibitors-A Focused Compound Screening and Structure-Based Design Approach. Journal of medicinal chemistry 63 (20) (2020)
Susanne Grunewald, Lillian R Klug, Thomas Mühlenberg, Jonas Lategahn, Johanna Falkenhorst, Ajia Town, Christiane Ehrt, Eva Wardelmann, Wolfgang Hartmann, Hans-Ulrich Schildhaus, Juergen Treckmann, Jonathan A Fletcher, Sascha Jung, Paul Czodrowski, Stephen Miller, Oleg Schmidt-Kittler, Daniel Rauh, Michael C Heinrich, Sebastian Bauer
Resistance to Avapritinib in PDGFRA-Driven GIST Is Caused by Secondary Mutations in the PDGFRA Kinase Domain. Cancer discovery 11 (1) (2020)
Janina Niggenaber, Julia Hardick, Jonas Lategahn, Daniel Rauh
Structure Defines Function: Clinically Relevant Mutations in ErbB Kinases. Journal of medicinal chemistry 63 (1) (2019)
Jonas Lategahn, Marina Keul, Philip Klövekorn, Hannah L Tumbrink, Janina Niggenaber, Matthias Philipp Müller, Luke Hodson, Maren Flaßhoff, Julia Hardick, Tobias Grabe, Julian Engel, Carsten Schultz-Fademrecht, Matthias Baumann, Julia Ketzer, Thomas Mühlenberg, Wolf Hiller, Georgia Günther, Anke Unger, Heiko Müller, Alena Heimsoeth, Christopher Golz, Bernhard Blank-Landeshammer, Laxmikanth Kollipara, René Peiman Zahedi, Carsten Strohmann, Jan G Hengstler, Willem A L van Otterlo, Sebastian Bauer, Daniel Rauh
Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S. Chemical science 10 (46) (2019)
Daniel Nascimento do Amaral, Jonas Lategahn, Harold Hilarion Fokoue, Eduardo Miguez Bastos da Silva, Carlos Mauricio R Sant'Anna, Daniel Rauh, Eliezer J Barreiro, Stefan Laufer, Lidia Moreira Lima
A novel scaffold for EGFR inhibition: Introducing N-(3-(3-phenylureido)quinoxalin-6-yl) acrylamide derivatives. Scientific reports 9 (1) (2019)
Patrik Wolle, Julian Engel, Steven Smith, Lisa Goebel, Elisabeth Hennes, Jonas Lategahn, Daniel Rauh
Characterization of Covalent Pyrazolopyrimidine-MKK7 Complexes and a Report on a Unique DFG-in/Leu-in Conformation of Mitogen-Activated Protein Kinase Kinase 7 (MKK7). Journal of medicinal chemistry 62 (11) (2019)

Jonas Lategahn.css-eqlu8i{font-size:small;padding-left:4px;} (J Lategahn)

Publication Activity (10 Years)

Top Topics

Top Venues

Jonas Lategahn (J Lategahn)