Matthias Philipp Müller (Matthias Müller, Matthias P Müller, M P Müller, Heiko Müller)

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 31

Top Topics

Saccharomyces Cerevisiae

Top Venues

Journal of medicinal chemistry

Nature communications

RSC medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Alina Teuber, Tom Schulz, B S Fletcher, Rajesh Gontla, Thomas Mühlenberg, M-L Zischinsky, Janina Niggenaber, Jörn Weisner, S B Kleinbölting, Jonas Lategahn, Sonja Sievers, Matthias Philipp Müller, Sebastian Bauer, Daniel Rauh
Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA. Nature communications 15 (1) (2024)
Alina Teuber, Tom Schulz, B S Fletcher, Rajesh Gontla, Thomas Mühlenberg, M-L Zischinsky, Janina Niggenaber, Jörn Weisner, S B Kleinbölting, Jonas Lategahn, Sonja Sievers, Matthias Philipp Müller, Sebastian Bauer, Daniel Rauh
Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA. Nature communications 15 (1) (2024)
Tonia Kirschner, Matthias Philipp Müller, Daniel Rauh
Targeting KRAS Diversity: Covalent Modulation of G12X and Beyond in Cancer Therapy. Journal of medicinal chemistry (2024)
Alina Teuber, Tom Schulz, B S Fletcher, Rajesh Gontla, Thomas Mühlenberg, M-L Zischinsky, Janina Niggenaber, Jörn Weisner, S B Kleinbölting, Jonas Lategahn, Sonja Sievers, Matthias Philipp Müller, Sebastian Bauer, Daniel Rauh
Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA. Nature communications 15 (1) (2024)
Alina Teuber, Tom Schulz, B S Fletcher, Rajesh Gontla, Thomas Mühlenberg, M-L Zischinsky, Janina Niggenaber, Jörn Weisner, S B Kleinbölting, Jonas Lategahn, Sonja Sievers, Matthias Philipp Müller, Sebastian Bauer, Daniel Rauh
Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA. Nature communications 15 (1) (2024)
Tonia Kirschner, Matthias Philipp Müller, Daniel Rauh
Targeting KRAS Diversity: Covalent Modulation of G12X and Beyond in Cancer Therapy. Journal of medicinal chemistry 67 (8) (2024)
Tobias Grabe, Kirujan Jeyakumar, Janina Niggenaber, Tom Schulz, Sandra Koska, Silke Kleinbölting, Michael Edmund Beck, Matthias Philipp Müller, Daniel Rauh
Addressing the Osimertinib Resistance Mutation EGFR-L858R/C797S with Reversible Aminopyrimidines. ACS medicinal chemistry letters 14 (5) (2023)
Lisa Goebel, Tonia Kirschner, Sandra Koska, Amrita Rai, Petra Janning, Stefano Maffini, Helge Vatheuer, Paul Czodrowski, Roger S Goody, Matthias Philipp Müller, Daniel Rauh
Targeting oncogenic KRasG13C with nucleotide-based covalent inhibitors. eLife 12 (2023)
Lisa Goebel, Tonia Kirschner, Sandra Koska, Amrita Rai, Petra Janning, Stefano Maffini, Helge Vatheuer, Paul Czodrowski, Roger S Goody, Matthias Philipp Müller, Daniel Rauh
Targeting oncogenic KRasG13C with nucleotide-based covalent inhibitors. eLife 12 (2023)
Lisa Goebel, Tonia Kirschner, Sandra Koska, Amrita Rai, Petra Janning, Stefano Maffini, Helge Vatheuer, Paul Czodrowski, Roger S Goody, Matthias Philipp Müller, Daniel Rauh
Targeting oncogenic KRasG13C with nucleotide-based covalent inhibitors. eLife 12 (2023)
Mike Bührmann, Shivakrishna Kallepu, Jonas D Warmuth, Jan N Wiese, Christiane Ehrt, Helge Vatheuer, Wolf Hiller, Carina Seitz, Laura Levy, Paul Czodrowski, Sonja Sievers, Matthias Philipp Müller, Daniel Rauh
Fragtory: Pharmacophore-Focused Design, Synthesis, and Evaluation of an sp 3 -Enriched Fragment Library. Journal of medicinal chemistry 66 (9) (2023)
Mike Bührmann, Shivakrishna Kallepu, Jonas D Warmuth, Jan N Wiese, Christiane Ehrt, Helge Vatheuer, Wolf Hiller, Carina Seitz, Laura Levy, Paul Czodrowski, Sonja Sievers, Matthias Philipp Müller, Daniel Rauh
Fragtory: Pharmacophore-Focused Design, Synthesis, and Evaluation of an sp 3 -Enriched Fragment Library. Journal of medicinal chemistry (2023)
Mike Bührmann, Shivakrishna Kallepu, Jonas D Warmuth, Jan N Wiese, Christiane Ehrt, Helge Vatheuer, Wolf Hiller, Carina Seitz, Laura Levy, Paul Czodrowski, Sonja Sievers, Matthias Philipp Müller, Daniel Rauh
Fragtory: Pharmacophore-Focused Design, Synthesis, and Evaluation of an sp 3 -Enriched Fragment Library. Journal of medicinal chemistry 66 (9) (2023)
Tobias Grabe, Kirujan Jeyakumar, Janina Niggenaber, Tom Schulz, Sandra Koska, Silke Kleinbölting, Michael Edmund Beck, Matthias Philipp Müller, Daniel Rauh
Addressing the Osimertinib Resistance Mutation EGFR-L858R/C797S with Reversible Aminopyrimidines. ACS medicinal chemistry letters 14 (5) (2023)
Shubhendu Palei, Jörn Weisner, Melina Vogt, Rajesh Gontla, Benjamin C Buchmuller, Christiane Ehrt, Tobias Grabe, Silke Kleinbölting, Matthias Philipp Müller, Guido H Clever, Daniel Rauh, Daniel Summerer
A high-throughput effector screen identifies a novel small molecule scaffold for inhibition of ten-eleven translocation dioxygenase 2. RSC medicinal chemistry 13 (12) (2022)
Paul Gehrtz, Shir Marom, Mike Bührmann, Julia Hardick, Silke Kleinbölting, Amit Shraga, Christian Dubiella, Ronen Gabizon, Jan N Wiese, Matthias Philipp Müller, Galit Cohen, Ilana Babaev, Khriesto Shurrush, Liat Avram, Efrat Resnick, Haim Barr, Daniel Rauh, Nir London
Optimization of Covalent MKK7 Inhibitors via Crude Nanomole-Scale Libraries. Journal of medicinal chemistry 65 (15) (2022)
Shubhendu Palei, Jörn Weisner, Melina Vogt, Rajesh Gontla, Benjamin C Buchmuller, Christiane Ehrt, Tobias Grabe, Silke Kleinbölting, Matthias Philipp Müller, Guido H Clever, Daniel Rauh, Daniel Summerer
A high-throughput effector screen identifies a novel small molecule scaffold for inhibition of ten-eleven translocation dioxygenase 2. RSC medicinal chemistry 13 (12) (2022)
Jonas Lategahn, Hannah L Tumbrink, Carsten Schultz-Fademrecht, Alena Heimsoeth, Lisa Werr, Janina Niggenaber, Marina Keul, Fatma Parmaksiz, Matthias Baumann, Sascha Menninger, Eldar Zent, Ina Landel, Jörn Weisner, Kirujan Jeyakumar, Leonie Heyden, Nicole Russ, Fabienne Müller, Carina Lorenz, Johannes Brägelmann, Inga Spille, Tobias Grabe, Matthias Philipp Müller, Johannes M Heuckmann, Bert M Klebl, Peter Nussbaumer, Martin L Sos, Daniel Rauh
Insight into Targeting Exon20 Insertion Mutations of the Epidermal Growth Factor Receptor with Wild Type-Sparing Inhibitors. Journal of medicinal chemistry 65 (9) (2022)
Jonas Lategahn, Julia Hardick, Tobias Grabe, Janina Niggenaber, Kirujan Jeyakumar, Marina Keul, Hannah L Tumbrink, Christian Becker, Luke Hodson, Tonia Kirschner, Philip Klövekorn, Julia Ketzer, Matthias Baumann, Susanne Terheyden, Anke Unger, Jörn Weisner, Matthias Philipp Müller, Willem A L van Otterlo, Sebastian Bauer, Daniel Rauh
Targeting Her2-insYVMA with Covalent Inhibitors-A Focused Compound Screening and Structure-Based Design Approach. Journal of medicinal chemistry 63 (20) (2020)
Lisa Goebel, Matthias Philipp Müller, Roger S Goody, Daniel Rauh
KRasG12C inhibitors in clinical trials: a short historical perspective. RSC medicinal chemistry 11 (7) (2020)
Niklas Uhlenbrock, Steven Smith, Jörn Weisner, Ina Landel, Marius Lindemann, Thien Anh Le, Julia Hardick, Rajesh Gontla, Rebekka Scheinpflug, Paul Czodrowski, Petra Janning, Laura Depta, Lena Quambusch, Matthias Philipp Müller, Bernd Engels, Daniel Rauh
Structural and chemical insights into the covalent-allosteric inhibition of the protein kinase Akt. Chemical science 10 (12) (2019)
Patrik Wolle, Matthias Philipp Müller, Daniel Rauh
Augmented Reality in Scientific Publications-Taking the Visualization of 3D Structures to the Next Level. ACS chemical biology 13 (3) (2019)
Jonas Lategahn, Marina Keul, Philip Klövekorn, Hannah L Tumbrink, Janina Niggenaber, Matthias Philipp Müller, Luke Hodson, Maren Flaßhoff, Julia Hardick, Tobias Grabe, Julian Engel, Carsten Schultz-Fademrecht, Matthias Baumann, Julia Ketzer, Thomas Mühlenberg, Wolf Hiller, Georgia Günther, Anke Unger, Heiko Müller, Alena Heimsoeth, Christopher Golz, Bernhard Blank-Landeshammer, Laxmikanth Kollipara, René Peiman Zahedi, Carsten Strohmann, Jan G Hengstler, Willem A L van Otterlo, Sebastian Bauer, Daniel Rauh
Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S. Chemical science 10 (46) (2019)
Jörn Weisner, Ina Landel, Christoph Reintjes, Niklas Uhlenbrock, Marija Trajkovic-Arsic, Niklas Dienstbier, Julia Hardick, Swetlana Ladigan, Marius Lindemann, Steven Smith, Lena Quambusch, Rebekka Scheinpflug, Laura Depta, Rajesh Gontla, Anke Unger, Matthias Philipp Müller, Matthias Baumann, Carsten Schultz-Fademrecht, Georgia Günther, Abdelouahid Maghnouj, Michael Pohl, Christian Teschendorf, Heiner Wolters, Richard Viebahn, Andrea Tannapfel, Waldemar Uhl, Jan G Hengstler, Stephan A Hahn, Jens Thomas Siveke, Daniel Rauh
Preclinical Efficacy of Covalent-Allosteric AKT Inhibitor Borussertib in Combination with Trametinib in KRAS-Mutant Pancreatic and Colorectal Cancer. Cancer research 79 (9) (2019)
Patrik Wolle, Matthias Philipp Müller, Daniel Rauh
Augmented Reality in Scientific Publications - Taking the Visualization of 3D Structures to the Next Level. ACS chemical biology 15 (1) (2019)
Sadasivam Jeganathan, Matthias Philipp Müller, Imtiaz Ali, Roger S Goody
Assays for Nucleotide Competitive Reversible and Irreversible Inhibitors of Ras GTPases. Biochemistry 57 (31) (2018)
Imtiaz Ali, Sungmin Eu, Daniel Koch, Nathalie Bleimling, Roger S Goody, Matthias Philipp Müller
Structure of the tandem PX-PH domains of Bem3 from Saccharomyces cerevisiae. Acta crystallographica. Section F, Structural biology communications 74 (Pt 5) (2018)
Roberta Tesch, Christian Becker, Matthias Philipp Müller, Michael Edmund Beck, Lena Quambusch, Matthäus Getlik, Jonas Lategahn, Niklas Uhlenbrock, Fanny Nascimento Costa, Marcelo D Polêto, Pedro de Sena Murteira Pinheiro, Daniel Alencar Rodrigues, Carlos Mauricio R Sant'Anna, Fabio Furlan Ferreira, Hugo Verli, Carlos Alberto Manssour Fraga, Daniel Rauh
An Unusual Intramolecular Halogen Bond Guides Conformational Selection. Angewandte Chemie (International ed. in English) 57 (31) (2018)
Amrita Rai, Roger S Goody, Matthias Philipp Müller
Multivalency in Rab effector interactions. Small GTPases 10 (1) (2017)
Matthias Philipp Müller, Roger S Goody
Molecular control of Rab activity by GEFs, GAPs and GDI. Small GTPases 9 (1-2) (2017)
Amrita Rai, Anastasia Oprisko, Jeremy Campos, Yangxue Fu, Timon Friese, Aymelt Itzen, Roger S Goody, Emerich Mihai Gazdag, Matthias Philipp Müller
bMERB domains are bivalent Rab8 family effectors evolved by gene duplication. eLife 5 (2016)