Takayoshi Suzuki

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 25

Top Topics

Histone Deacetylase

Cognitive Decline

Top Venues

Journal of medicinal chemistry

Journal of clinical medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Runze Zhao, null Ismiyarto, Da-Yang Zhou, Kaori Asano, Takayoshi Suzuki, Hiroaki Sasai, Takeyuki Suzuki
General Synthesis of meso -1,4-Dialdehydes and Their Application in Ir-Catalyzed Asymmetric Tishchenko Reactions. ACS omega 9 (16) (2024)
Takayoshi Suzuki, Haruto Kurata, Tomohiko Ohwada, Hideyuki Onodera
Journal of Medicinal Chemistry Collection: Drug Discovery in Japan. Journal of medicinal chemistry (2024)
Runze Zhao, null Ismiyarto, Da-Yang Zhou, Kaori Asano, Takayoshi Suzuki, Hiroaki Sasai, Takeyuki Suzuki
General Synthesis of meso -1,4-Dialdehydes and Their Application in Ir-Catalyzed Asymmetric Tishchenko Reactions. ACS omega 9 (16) (2024)
Anirban Mukherjee, Farzad Zamani, Takayoshi Suzuki
Evolution of Slow-Binding Inhibitors Targeting Histone Deacetylase Isoforms. Journal of medicinal chemistry (2023)
Yukihiro Itoh, Peng Zhan, Toshifumi Tojo, Pattaporn Jaikhan, Yosuke Ota, Miki Suzuki, Ying Li, Zi Hui, Yukiko Moriyama, Yuri Takada, Yasunobu Yamashita, Makoto Oba, Shusaku Uchida, Mitsuharu Masuda, Shinji Ito, Yoshihiro Sowa, Toshiyuki Sakai, Takayoshi Suzuki
Discovery of Selective Histone Deacetylase 1 and 2 Inhibitors: Screening of a Focused Library Constructed by Click Chemistry, Kinetic Binding Analysis, and Biological Evaluation. Journal of medicinal chemistry (2023)
Rui Jiang, null Ismiyarto, Tsukasa Abe, Da-Yang Zhou, Kaori Asano, Takayoshi Suzuki, Hiroaki Sasai, Takeyuki Suzuki
Using α- and β-Epimerizations of cis -2,3-Bis(hydroxymethyl)-γ-butyrolactone for the Synthesis of Both Enantiomers of Enterolactone. The Journal of organic chemistry 87 (8) (2022)
Yosuke Ota, Yukihiro Itoh, Takashi Kurohara, Ritesh Singh, Elghareeb E Elboray, Chenliang Hu, Farzad Zamani, Anirban Mukherjee, Yuri Takada, Yasunobu Yamashita, Mie Morita, Mano Horinaka, Yoshihiro Sowa, Mitsuharu Masuda, Toshiyuki Sakai, Takayoshi Suzuki
Cancer-Cell-Selective Targeting by Arylcyclopropylamine-Vorinostat Conjugates. ACS medicinal chemistry letters 13 (10) (2022)
Tetsuya Iida, Yukihiro Itoh, Yukari Takahashi, Yasunobu Yamashita, Takashi Kurohara, Yuka Miyake, Makoto Oba, Takayoshi Suzuki
Design, Synthesis, and Biological Evaluation of Lysine Demethylase 5 C Degraders. ChemMedChem 16 (10) (2021)
Dennis C Liotta, James C Barrow, Kelly Chibale, Maria Laura Bolognesi, Stuart J Conway, William Alexander Denny, Ke Ding, Stefan A Laufer, Luhua Lai, Hong Liu, Nouri Neamati, Takayoshi Suzuki, Nicholas A Meanwell, Wendy B Young
Simplifying Submission Requirements for the Journal of Medicinal Chemistry. Journal of medicinal chemistry 64 (12) (2021)
Muthuraj Prakash, Yukihiro Itoh, Yoshie Fujiwara, Yukari Takahashi, Yuri Takada, Paolo Mellini, Elghareeb E Elboray, Mitsuhiro Terao, Yasunobu Yamashita, Chika Yamamoto, Takao Yamaguchi, Masayuki Kotoku, Yuki Kitao, Ritesh Singh, Rohini Roy, Satoshi Obika, Makoto Oba, Dan Ohtan Wang, Takayoshi Suzuki
Identification of Potent and Selective Inhibitors of Fat Mass Obesity-Associated Protein Using a Fragment-Merging Approach. Journal of medicinal chemistry 64 (21) (2021)
Takashi Kurohara, Keita Tanaka, Daisuke Takahashi, Satoshi Ueda, Yasunobu Yamashita, Yuri Takada, Hirokazu Takeshima, Shengwang Yu, Yukihiro Itoh, Koji Hase, Takayoshi Suzuki
Identification of Novel Histone Deacetylase 6-Selective Inhibitors Bearing 3,3,3-Trifluorolactic Amide (TFLAM) Motif as a Zinc Binding Group. Chembiochem : a European journal of chemical biology 22 (22) (2021)
Farzad Zamani, Takayoshi Suzuki
Synthetic RNA Modulators in Drug Discovery. Journal of medicinal chemistry 64 (11) (2021)
Satoshi Shuto, Takayoshi Suzuki
Excellence in Medicinal Chemistry Research from Japan. Journal of medicinal chemistry 63 (17) (2020)
Goichi Tatsumi, Masahiro Kawahara, Ryusuke Yamamoto, Masakatsu Hishizawa, Katsuyuki Kito, Takayoshi Suzuki, Akifumi Takaori-Kondo, Akira Andoh
LSD1-mediated repression of GFI1 super-enhancer plays an essential role in erythroleukemia. Leukemia 34 (3) (2019)
Shusuke Ogihara, Toru Komatsu, Yukihiro Itoh, Yuka Miyake, Takayoshi Suzuki, Kouichi Yanagi, Yusuke Kimura, Tasuku Ueno, Kenjiro Hanaoka, Hirotatsu Kojima, Takayoshi Okabe, Tetsuo Nagano, Yasuteru Urano
Metabolic-Pathway-Oriented Screening Targeting S-Adenosyl-l-methionine Reveals the Epigenetic Remodeling Activities of Naturally Occurring Catechols. Journal of the American Chemical Society 142 (1) (2019)
Teresa Diaz-Perdigon, Francisco B Belloch, Ana Ricobaraza, Elghareeb E Elboray, Takayoshi Suzuki, Rosa M Tordera, Elena Puerta
Early sirtuin 2 inhibition prevents age-related cognitive decline in a senescence-accelerated mouse model. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 45 (2) (2019)
Masayuki Kotoku, Takaki Maeba, Shingo Fujioka, Masahiro Yokota, Noriyoshi Seki, Keisuke Ito, Yoshihiro Suwa, Taku Ikenogami, Kazuyuki Hirata, Yasunori Hase, Yoshiaki Katsuda, Naoki Miyagawa, Kojo Arita, Kota Asahina, Masato Noguchi, Akihiro Nomura, Satoki Doi, Tsuyoshi Adachi, Paul Crowe, Haiyan Tao, Scott Thacher, Hiromasa Hashimoto, Takayoshi Suzuki, Makoto Shiozaki
Discovery of Second Generation RORγ Inhibitors Composed of an Azole Scaffold. Journal of medicinal chemistry 62 (5) (2019)
Toshiki Etani, Taku Naiki, Aya Naiki-Ito, Takayoshi Suzuki, Keitaro Iida, Satoshi Nozaki, Hiroyuki Kato, Yuko Nagayasu, Shugo Suzuki, Noriyasu Kawai, Takahiro Yasui, Satoru Takahashi
NCL1, A Highly Selective Lysine-Specific Demethylase 1 Inhibitor, Suppresses Castration-Resistant Prostate Cancer Growth via Regulation of Apoptosis and Autophagy. Journal of clinical medicine 8 (4) (2019)
Takayoshi Suzuki
Special Issue: (Bio)Chemical Aspects of Epigenetics. Chemical record (New York, N.Y.) 18 (12) (2019)
Paolo Mellini, Yukihiro Itoh, Elghareeb E Elboray, Hiroki Tsumoto, Ying Li, Miki Suzuki, Yukari Takahashi, Toshifumi Tojo, Takashi Kurohara, Yuka Miyake, Yuri Miura, Yuki Kitao, Masayuki Kotoku, Tetsuya Iida, Takayoshi Suzuki
Identification of Diketopiperazine-Containing 2-Anilinobenzamides as Potent Sirtuin 2 (SIRT2)-Selective Inhibitors Targeting the "Selectivity Pocket", Substrate-Binding Site, and NAD+-Binding Site. Journal of medicinal chemistry 62 (12) (2019)
Miki Matsui, Kyoko Terasawa, Junko Kajikuri, Hiroaki Kito, Kyoko Endo, Pattaporn Poonsawas, Takayoshi Suzuki, Susumu Ohya
Histone Deacetylases Enhance Ca2+-Activated K⁺ Channel KCa3.1 Expression in Murine Inflammatory CD4⁺ T Cells. International journal of molecular sciences 19 (10) (2018)
Martin Marek, Tajith B Shaik, Tino Heimburg, Alokta Chakrabarti, Julien Lancelot, Elizabeth Ramos-Morales, Cyrielle Da Veiga, Dmitrii Kalinin, Jelena Melesina, Dina Robaa, Karin Schmidtkunz, Takayoshi Suzuki, Ralph Holl, Eric Ennifar, Raymond J Pierce, Manfred Jung, Wolfgang Sippl, Christophe Romier
Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants. Journal of medicinal chemistry 61 (22) (2018)
Yosuke Ota, Taeko Kakizawa, Yukihiro Itoh, Takayoshi Suzuki
Design, Synthesis, and In Vitro Evaluation of Novel Histone H3 Peptide-Based LSD1 Inactivators Incorporating α,α-Disubstituted Amino Acids with γ-Turn-Inducing Structures. Molecules (Basel, Switzerland) 23 (5) (2018)
Fumihiro Higuchi, Shusaku Uchida, Hirotaka Yamagata, Naoko Abe-Higuchi, Teruyuki Hobara, Kumiko Hara, Ayumi Kobayashi, Tatsushi Shintaku, Yukihiro Itoh, Takayoshi Suzuki, Yoshifumi Watanabe
Hippocampal MicroRNA-124 Enhances Chronic Stress Resilience in Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience 36 (27) (2017)
Paolo Mellini, Yukihiro Itoh, Hiroki Tsumoto, Ying Li, Miki Suzuki, Natsuko Tokuda, Taeko Kakizawa, Yuri Miura, Jun Takeuchi, Maija Lahtela-Kakkonen, Takayoshi Suzuki
Potent mechanism-based sirtuin-2-selective inhibition by an in situ-generated occupant of the substrate-binding site, "selectivity pocket" and NAD+-binding site. Chemical science 8 (9) (2017)