Xi Chen

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 29

Top Venues

Nature communications

Nucleic acids research

Bioinformatics (Oxford, England)

Research square

Southern University of Science and Technology

University of Manchester (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Southern University of Science and Technology Apr 26 2019

China

Assistant Professor :: Department of Biology

Wellcome Trust Sanger Institute Mar 14 2016 - Mar 31 2019

United Kingdom

Senior Staff Scientist :: Cellular Genetics

European Bioinformatics Institute Oct 21 2013 - Mar 13 2016

United Kingdom

Postdoctoral Fellow

University of Manchester Oct 01 2012 - Sep 30 2013

United Kingdom

Research Associate :: Faculty of Life Sciences

Education History

University of Manchester Oct 01 2009 - Sep 30 2012

United Kingdom

PHD :: Faculty of Life Sciences

Peking University Sep 01 2005 - Jul 31 2009

China

BSC :: School of Basic Medical Sciences

Publications

Danling Zhu, Yi Wen, Yifang Tan, Xi Chen, Zhe Wu
A simple, robust, cost-effective, and low-input ChIP-seq method for profiling histone modifications and Pol II in plants. The New phytologist (2024)
Ali Sina Booeshaghi, Xi Chen, Lior Pachter
A machine-readable specification for genomics assays. Bioinformatics (Oxford, England) 40 (4) (2024)
Ying Ye, Wenyan Xie, Zhaoru Ma, Xuepeng Wang, Yi Wen, Xuemei Li, Hongqian Qi, Hao Wu, Jinnan An, Yan Jiang, Xinyi Lu, Guokai Chen, Shijun Hu, Elizabeth A Blaber, Xi Chen, Lei Chang, Wensheng Zhang
Conserved mechanisms of self-renewal and pluripotency in mouse and human ESCs regulated by simulated microgravity using a 3D clinostat. Cell death discovery 10 (1) (2024)
Ali Sina Booeshaghi, Xi Chen, Lior Pachter
A machine-readable specification for genomics assays. Bioinformatics (Oxford, England) 40 (4) (2024)
Ying Ye, Wenyan Xie, Zhaoru Ma, Xuepeng Wang, Yi Wen, Xuemei Li, Hongqian Qi, Hao Wu, Jinnan An, Yan Jiang, Xinyi Lu, Guokai Chen, Shijun Hu, Elizabeth A Blaber, Xi Chen, Lei Chang, Wensheng Zhang
Conserved mechanisms of self-renewal and pluripotency in mouse and human ESCs regulated by simulated microgravity using a 3D clinostat. Cell death discovery 10 (1) (2024)
Qiushi Xu, Yunlong Zhang, Wei Xu, Dong Liu, Wenfei Jin, Xi Chen, Ni Hong
The chromatin accessibility dynamics during cell fate specifications in zebrafish early embryogenesis. Nucleic acids research 52 (6) (2024)
Ali Sina Booeshaghi, Xi Chen, Lior Pachter
A machine-readable specification for genomics assays. Bioinformatics (Oxford, England) 40 (4) (2024)
Qiushi Xu, Yunlong Zhang, Wei Xu, Dong Liu, Wenfei Jin, Xi Chen, Ni Hong
The chromatin accessibility dynamics during cell fate specifications in zebrafish early embryogenesis. Nucleic acids research 52 (6) (2024)
Qiushi Xu, Yunlong Zhang, Wei Xu, Dong Liu, Wenfei Jin, Xi Chen, Ni Hong
The chromatin accessibility dynamics during cell fate specifications in zebrafish early embryogenesis. Nucleic acids research (2024)
Qiushi Xu, Yunlong Zhang, Wei Xu, Dong Liu, Wenfei Jin, Xi Chen, Ni Hong
The chromatin accessibility dynamics during cell fate specifications in zebrafish early embryogenesis. Nucleic acids research 52 (6) (2024)
Ziqi Zhang, Haoran Sun, Ragunathan Mariappan, Xi Chen, Xinyu Chen, Mika S Jain, Mirjana Efremova, Sarah A Teichmann, Vaibhav Rajan, Xiuwei Zhang
scMoMaT jointly performs single cell mosaic integration and multi-modal bio-marker detection. Nature communications 14 (1) (2023)
Ziqi Zhang, Haoran Sun, Ragunathan Mariappan, Xi Chen, Xinyu Chen, Mika S Jain, Mirjana Efremova, Sarah A Teichmann, Vaibhav Rajan, Xiuwei Zhang
scMoMaT jointly performs single cell mosaic integration and multi-modal bio-marker detection. Nature communications 14 (1) (2023)
Ziqi Zhang, Haoran Sun, Ragunathan Mariappan, Xi Chen, Xinyu Chen, Mika S Jain, Mirjana Efremova, Sarah A Teichmann, Vaibhav Rajan, Xiuwei Zhang
scMoMaT jointly performs single cell mosaic integration and multi-modal bio-marker detection. Nature communications 14 (1) (2023)
Ziqi Zhang, Haoran Sun, Ragunathan Mariappan, Xi Chen, Xinyu Chen, Mika S Jain, Mirjana Efremova, Sarah A Teichmann, Vaibhav Rajan, Xiuwei Zhang
scMoMaT jointly performs single cell mosaic integration and multi-modal bio-marker detection. Nature communications 14 (1) (2023)
Hechen Li, Ziqi Zhang, Michael Squires, Xi Chen, Xiuwei Zhang
scMultiSim: simulation of multi-modality single cell data guided by cell-cell interactions and gene regulatory networks. Research square (2023)
Danling Zhu, Yi Wen, Wanyue Yao, Haiyan Zheng, Sixian Zhou, Qiqi Zhang, Li-Jia Qu, Xi Chen, Zhe Wu
Distinct chromatin signatures in the Arabidopsis male gametophyte. Nature genetics (2023)
Yan Mei, Xiumei Wang, Ji Zhang, Dan Liu, Junjie He, Chunliu Huang, Jing Liao, Yingzhao Wang, Yongyi Feng, Hongyu Li, Xiuying Liu, Lingdan Chen, Wei Yi, Xi Chen, Hong-Min Bai, Xinyu Wang, Yiyi Li, Lixiang Wang, Zhigang Liang, Xianwen Ren, Li Qiu, Yuan Hui, Qingling Zhang, Qibing Leng, Jun Chen, Guangshuai Jia
Siglec-9 acts as an immune-checkpoint molecule on macrophages in glioblastoma, restricting T-cell priming and immunotherapy response. Nature cancer (2023)
Xuepeng Wang, Chengcheng Song, Ying Ye, Yashi Gu, Xuemei Li, Peixin Chen, Dongliang Leng, Jing Xiao, Hao Wu, Sisi Xie, Weiwei Liu, Qi Zhao, Di Chen, Xi Chen, Qiang Wu, Guokai Chen, Wensheng Zhang
BRD9-mediated control of the TGF-β/Activin/Nodal pathway regulates self-renewal and differentiation of human embryonic stem cells and progression of cancer cells. Nucleic acids research (2023)
Ali Sina Booeshaghi, Xi Chen, Lior Pachter
A machine-readable specification for genomics assays. bioRxiv : the preprint server for biology (2023)
Xiuwei Zhang, Hechen Li, Ziqi Zhang, Michael Squires, Xi Chen
scMultiSim: simulation of single cell multi-omics and spatial data guided by gene regulatory networks and cell-cell interactions. Research square (2023)
Wei Xu, Weilong Yang, Yunlong Zhang, Yawen Chen, Ni Hong, Qian Zhang, Xuefei Wang, Yukun Hu, Kun Song, Wenfei Jin, Xi Chen
ISSAAC-seq enables sensitive and flexible multimodal profiling of chromatin accessibility and gene expression in single cells. Nature methods 19 (10) (2022)
Deyue Yang, Fengli Zhao, Danling Zhu, Xi Chen, Xiangxiong Kong, Yufeng Wu, Min Chen, Jiamu Du, Li-Jia Qu, Zhe Wu
Progressive chromatin silencing of ABA biosynthesis genes permits seed germination in Arabidopsis. The Plant cell 34 (8) (2022)
Deng Tan, Rui Chen, Yuejian Mo, Shu Gu, Jiao Ma, Wei Xu, Xibin Lu, Huiyu He, Fan Jiang, Weimin Fan, Yili Wang, Xi Chen, Wei Huang
Quantitative control of noise in mammalian gene expression by dynamic histone regulation. eLife 10 (2021)
Xuefei Wang, Xiangru Shen, Shan Chen, Hongyi Liu, Ni Hong, Hanbing Zhong, Xi Chen, Wenfei Jin
Reinvestigation of Classic T Cell Subsets and Identification of Novel Cell Subpopulations by Single-Cell RNA Sequencing. Journal of immunology (Baltimore, Md. : 1950) 208 (2) (2021)
Wei Xu, Yi Wen, Yingying Liang, Qiushi Xu, Xuefei Wang, Wenfei Jin, Xi Chen
A plate-based single-cell ATAC-seq workflow for fast and robust profiling of chromatin accessibility. Nature protocols 16 (8) (2021)
Bidesh Mahata, Jhuma Pramanik, Louise van der Weyden, Krzysztof Polański, Gozde Kar, Angela Riedel, Xi Chen, Nuno A Fonseca, Kousik Kundu, Lia S Campos, Edward J Ryder, Graham Duddy, Izabela Walczak, Klaus Okkenhaug, David J Adams, Jacqueline D Shields, Sarah A Teichmann
Tumors induce de novo steroid biosynthesis in T cells to evade immunity. Nature communications 11 (1) (2020)
Megan S F Soon, Hyun Jae Lee, Jessica A Engel, Jasmin Straube, Bryce S Thomas, Clara P S Pernold, Lachlan S Clarke, Pawat Laohamonthonkul, Rohit N Haldar, Cameron G Williams, Lianne I M Lansink, Marcela L Moreira, Michael Bramhall, Lambros T Koufariotis, Scott Wood, Xi Chen, Kylie Renee James, Tapio Lönnberg, Steven W Lane, Gabrielle T Belz, Christian R Engwerda, David S Khoury, Miles P Davenport, Valentine Svensson, Sarah A Teichmann, Ashraful Haque
Transcriptome dynamics of CD4+ T cells during malaria maps gradual transit from effector to memory. Nature immunology 21 (12) (2020)
Xuefei Gao, Monika Nowak-Imialek, Xi Chen, Dongsheng Chen, Doris Herrmann, Degong Ruan, Andy Chun Hang Chen, Melanie A Eckersley-Maslin, Shakil Ahmad, Yin Lau Lee, Toshihiro Kobayashi, David Ryan, Jixing Zhong, Jiacheng Zhu, Jian Wu, Guocheng Lan, Stoyan Petkov, Jian Yang, Liliana Antunes, Lia S Campos, Beiyuan Fu, Shengpeng Wang, Yu Yong, Xiaomin Wang, Song-Guo Xue, Liangpeng Ge, Zuohua Liu, Yong Huang, Tao Nie, Peng Li, Donghai Wu, Duanqing Pei, Yi Zhang, Liming Lu, Fengtang Yang, Susan J Kimber, Wolf Reik, Xiangang Zou, Zhouchun Shang, Liangxue Lai, M Azim Surani, Patrick P L Tam, Asif Ahmed, William Shu Biu Yeung, Sarah A Teichmann, Andres Hilfiker, Pengtao Liu
Establishment of porcine and human expanded potential stem cells. Nature cell biology 21 (6) (2019)
Xi Chen, Ricardo J Miragaia, Kedar Nath Natrajan, Sarah A Teichmann
A rapid and robust method for single cell chromatin accessibility profiling. Nature communications 9 (1) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Xi Chen