Xiaojin Zhang

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 25

Top Venues

Journal of medicinal chemistry

Expert opinion on therapeutic patents

Angewandte Chemie (International ed. in English)

Angewandte Chemie (Weinheim an der Bergstrasse, Germany)

China Pharmaceutcial University

This page only lists publications with an associated author ORCID identifier.

Affiliation History

China Pharmaceutcial University

China

Deputy Director of Department of Chemistry, Associate Professor of Medicinal Chemistry

Publications

Xinye Yang, Yong Li, Shengqiang Pan, Facheng Ma, Hong Chen, Jinhui Deng, Jie Yue, Qijie Gong, Mi Zheng, Ying Zeng, Jing Li, Yingjun Zhang, Xiaojun Wang, Xiaojin Zhang
Discovery of a Potent and Orally Bioavailable Xanthine Oxidase/Urate Transporter 1 Dual Inhibitor as a Potential Treatment for Hyperuricemia and Gout. Journal of medicinal chemistry 67 (16) (2024)
Yuhang Li, Le Yang, Xiaoran Li, Xiaojin Zhang
Inhibition of GTPase KRAS G12D : a review of patent literature. Expert opinion on therapeutic patents 34 (8) (2024)
Yuhang Li, Le Yang, Xiaoran Li, Xiaojin Zhang
Inhibition of GTPase KRAS G12D : a review of patent literature. Expert opinion on therapeutic patents (2024)
Yuhang Li, Le Yang, Xiaoran Li, Xiaojin Zhang
Inhibition of GTPase KRAS G12D : a review of patent literature. Expert opinion on therapeutic patents 34 (8) (2024)
Xinye Yang, Yong Li, Shengqiang Pan, Facheng Ma, Hong Chen, Jinhui Deng, Jie Yue, Qijie Gong, Mi Zheng, Ying Zeng, Jing Li, Yingjun Zhang, Xiaojun Wang, Xiaojin Zhang
Discovery of a Potent and Orally Bioavailable Xanthine Oxidase/Urate Transporter 1 Dual Inhibitor as a Potential Treatment for Hyperuricemia and Gout. Journal of medicinal chemistry (2024)
Xinye Yang, Yong Li, Shengqiang Pan, Facheng Ma, Hong Chen, Jinhui Deng, Jie Yue, Qijie Gong, Mi Zheng, Ying Zeng, Jing Li, Yingjun Zhang, Xiaojun Wang, Xiaojin Zhang
Discovery of a Potent and Orally Bioavailable Xanthine Oxidase/Urate Transporter 1 Dual Inhibitor as a Potential Treatment for Hyperuricemia and Gout. Journal of medicinal chemistry 67 (16) (2024)
Yue Wu, Linjian Zhang, Zhuoli Sun, Xusheng Qiu, Yafen Chen, Kaijun Su, Le Yang, Zhongqiu Du, Ying Dong, Fulai Yang, Xiang Li, Xiaojin Zhang
Preferred Conformation-Guided Discovery of Potent and Orally Active HIF Prolyl Hydroxylase 2 Inhibitors for the Treatment of Anemia. Journal of medicinal chemistry (2023)
Thomas P Corner, Ryan Z R Teo, Yue Wu, Eidarus Salah, Yu Nakashima, Giorgia Fiorini, Anthony Tumber, Amelia Brasnett, James P Holt-Martyn, William D Figg, Xiaojin Zhang, Lennart Brewitz, Christopher J Schofield
Structure-guided optimisation of N -hydroxythiazole-derived inhibitors of factor inhibiting hypoxia-inducible factor-α. Chemical science 14 (43) (2023)
Qijie Gong, Xiang Li, Tian Li, Xingsen Wu, Jiabao Hu, Fulai Yang, Xiaojin Zhang
A Carbon-Carbon Bond Cleavage-Based Prodrug Activation Strategy Applied to β-Lapachone for Cancer-Specific Targeting. Angewandte Chemie (International ed. in English) 61 (40) (2022)
Zhihong Li, Yue Wu, Shuai Zhen, Kaijun Su, Linjian Zhang, Fulai Yang, Michael A McDonough, Christopher J Schofield, Xiaojin Zhang
In Situ Inhibitor Synthesis and Screening by Fluorescence Polarization: An Efficient Approach for Accelerating Drug Discovery. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 134 (45) (2022)
Zhihong Li, Yue Wu, Shuai Zhen, Kaijun Su, Linjian Zhang, Fulai Yang, Michael A McDonough, Christopher J Schofield, Xiaojin Zhang
In Situ Inhibitor Synthesis and Screening by Fluorescence Polarization: An Efficient Approach for Accelerating Drug Discovery. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 134 (45) (2022)
Zhihong Li, Yue Wu, Shuai Zhen, Kaijun Su, Linjian Zhang, Fulai Yang, Michael A McDonough, Christopher J Schofield, Xiaojin Zhang
In Situ Inhibitor Synthesis and Screening by Fluorescence Polarization: An Efficient Approach for Accelerating Drug Discovery. Angewandte Chemie (International ed. in English) 61 (45) (2022)
Yue Wu, Zhihong Li, Michael A McDonough, Christopher J Schofield, Xiaojin Zhang
Inhibition of the Oxygen-Sensing Asparaginyl Hydroxylase Factor Inhibiting Hypoxia-Inducible Factor: A Potential Hypoxia Response Modulating Strategy. Journal of medicinal chemistry 64 (11) (2021)
Yancheng Yu, Fulai Yang, Quanwei Yu, Simeng Liu, Chenyang Wu, Kaijun Su, Le Yang, Xiaoqian Bao, Zhihong Li, Xiang Li, Xiaojin Zhang
Discovery of a Potent and Orally Bioavailable Hypoxia-Inducible Factor 2α (HIF-2α) Agonist and Its Synergistic Therapy with Prolyl Hydroxylase Inhibitors for the Treatment of Renal Anemia. Journal of medicinal chemistry 64 (23) (2021)
Chenyang Wu, Xin Cao, Xiaojin Zhang
VISTA inhibitors in cancer immunotherapy: a short perspective on recent progresses. RSC medicinal chemistry 12 (10) (2021)
Pengfei Wang, Qijie Gong, Jiabao Hu, Xiang Li, Xiaojin Zhang
Reactive Oxygen Species (ROS)-Responsive Prodrugs, Probes, and Theranostic Prodrugs: Applications in the ROS-Related Diseases. Journal of medicinal chemistry 64 (1) (2020)
Zhihong Li, Kaijun Su, Zhensheng Jiang, Yancheng Yu, Qi-Dong You, Xiaojin Zhang
Correction to Photoactivatable Prolyl Hydroxylase 2 Inhibitors for Stabilizing the Hypoxia-Inducible Factor with Light. Journal of medicinal chemistry 63 (9) (2020)
Xiaojin Zhang, Yonghua Lei, Tianhan Hu, Yue Wu, Zhihong Li, Zhensheng Jiang, Changyong Yang, Lianshan Zhang, Qi-Dong You
Discovery of Clinical Candidate (5-(3-(4-Chlorophenoxy)prop-1-yn-1-yl)-3-hydroxypicolinoyl)glycine, an Orally Bioavailable Prolyl Hydroxylase Inhibitor for the Treatment of Anemia. Journal of medicinal chemistry 63 (17) (2020)
Zhihong Li, Kaijun Su, Zhensheng Jiang, Yancheng Yu, Qi-Dong You, Xiaojin Zhang
Photoactivatable Prolyl Hydroxylase 2 Inhibitors for Stabilizing the Hypoxia-Inducible Factor with Light. Journal of medicinal chemistry 62 (16) (2019)
Zhan Yu, Zhihong Li, Quanwei Yu, Zhi Wang, Huilin Song, Hanyu Sun, Rufeng Fan, Angzhi Bi, Jun Zhang, Xiaojin Zhang
Discovery of prolyl hydroxylase 2 inhibitors with new chemical scaffolds as in vivo active erythropoietin inducers through a combined virtual screening strategy. Chemical biology & drug design 95 (2) (2019)
Zhihong Li, Qi-Dong You, Xiaojin Zhang
Small-Molecule Modulators of the Hypoxia-Inducible Factor Pathway: Development and Therapeutic Applications. Journal of medicinal chemistry 62 (12) (2019)
Xingsen Wu, Xiang Li, Zhihong Li, Yancheng Yu, Qi-Dong You, Xiaojin Zhang
Discovery of Nonquinone Substrates for NAD(P)H: Quinone Oxidoreductase 1 (NQO1) as Effective Intracellular ROS Generators for the Treatment of Drug-Resistant Non-Small-Cell Lung Cancer. Journal of medicinal chemistry 61 (24) (2018)
Yue Wu, Zhensheng Jiang, Zhihong Li, Jing Gu, Qi-Dong You, Xiaojin Zhang
Click Chemistry-Based Discovery of [3-Hydroxy-5-(1 H-1,2,3-triazol-4-yl)picolinoyl]glycines as Orally Active Hypoxia-Inducing Factor Prolyl Hydroxylase Inhibitors with Favorable Safety Profiles for the Treatment of Anemia. Journal of medicinal chemistry 61 (12) (2018)
Xian Zhang, Xiang Li, Zhihong Li, Xingsen Wu, Yue Wu, Qi-Dong You, Xiaojin Zhang
An NAD(P)H:Quinone Oxidoreductase 1 Responsive and Self-Immolative Prodrug of 5-Fluorouracil for Safe and Effective Cancer Therapy. Organic letters 20 (12) (2018)
Xiang Li, Yue Wu, Yanyan Wang, Qidong You, Xiaojin Zhang
'Click Chemistry' Synthesis of Novel Natural Product-Like Caged Xanthones Bearing a 1,2,3-Triazole Moiety with Improved Druglike Properties as Orally Active Antitumor Agents. Molecules (Basel, Switzerland) 22 (11) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Xiaojin Zhang