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TF-Prioritizer: a Java pipeline to prioritize condition-specific transcription factors.

Markus HoffmannNico TrummerLeon SchwartzJakub JankowskiHye Kyung LeeLina-Liv WillruthOlga E LazarevaKevin YuanNina BaumgartenFlorian SchmidtJan BaumbachMarcel H SchulzDavid B BlumenthalLothar HennighausenMarkus List
Published in: GigaScience (2023)
TF-Prioritizer accepts ATAC, DNase, or ChIP sequencing and RNA sequencing data as input and identifies TFs with differential activity, thus offering an understanding of genome-wide gene regulation, potential pathogenesis, and therapeutic targets in biomedical research.
Keyphrases
  • genome wide
  • single cell
  • transcription factor
  • high throughput
  • dna methylation
  • electronic health record
  • copy number
  • circulating tumor cells
  • big data
  • gene expression
  • human health
  • dna binding