Andrew C Kruse (Andrew Kruse)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 82

Top Venues

Nature

Science (New York, N.Y.)

Nature chemical biology

Proceedings of the National Academy of Sciences of the United States of America

Harvard Medical School

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Harvard Medical School Jul 01 2014

United States

Assistant Professor :: Biological Chemistry and Molecular Pharmacology

Publications

Karanbir S Pahil, Morgan S A Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek, Fabian Dey, Dieter Muri, Remo Baettig, Michael Lobritz, Kenneth A Bradley, Andrew C Kruse, Daniel E Kahne
A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature 625 (7995) (2024)
Jiankun Lyu, Nicholas J Kapolka, Ryan Gumpper, Assaf Alon, Liang Wang, Manish Kumar Jain, Ximena Barros-Álvarez, Kensuke Sakamoto, Yoojoong Kim, Jeffrey F DiBerto, Kuglae Kim, Isabella S Glenn, Tia A Tummino, Sijie Huang, John J Irwin, Olga O Tarkhanova, Yurii S Moroz, Georgios Skiniotis, Andrew C Kruse, Brian K Shoichet, Bryan L Roth
AlphaFold2 structures guide prospective ligand discovery. Science (New York, N.Y.) 384 (6702) (2024)
Karanbir S Pahil, Morgan S A Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek, Fabian Dey, Dieter Muri, Remo Baettig, Michael Lobritz, Kenneth A Bradley, Andrew C Kruse, Daniel E Kahne
A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature (2024)
Jiankun Lyu, Nicholas J Kapolka, Ryan Gumpper, Assaf Alon, Liang Wang, Manish Kumar Jain, Ximena Barros-Álvarez, Kensuke Sakamoto, Yoojoong Kim, Jeffrey F DiBerto, Kuglae Kim, Isabella S Glenn, Tia A Tummino, Sijie Huang, John J Irwin, Olga O Tarkhanova, Yurii S Moroz, Georgios Skiniotis, Andrew C Kruse, Brian K Shoichet, Bryan L Roth
AlphaFold2 structures guide prospective ligand discovery. Science (New York, N.Y.) 384 (6702) (2024)
Jeffrey S Smith, Ari S Hilibrand, Meredith A Skiba, Andrew N Dates, Victor G Calvillo-Miranda, Andrew C Kruse
The M3 Muscarinic Acetylcholine Receptor Can Signal through Multiple G Protein Families. Molecular pharmacology 105 (6) (2024)
Jeffrey S Smith, Ari S Hilibrand, Meredith A Skiba, Andrew N Dates, Victor G Calvillo-Miranda, Andrew C Kruse
The M3 Muscarinic Acetylcholine Receptor Can Signal through Multiple G Protein Families. Molecular pharmacology 105 (6) (2024)
Sarah C Erlandson, Jialu Wang, Haoran Jiang, James Osei-Owusu, Howard A Rockman, Andrew C Kruse
Engineering and Characterization of a Long-Half-Life Relaxin Receptor RXFP1 Agonist. Molecular pharmaceutics (2024)
Karanbir S Pahil, Morgan S A Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek, Fabian Dey, Dieter Muri, Remo Baettig, Michael Lobritz, Kenneth A Bradley, Andrew C Kruse, Daniel E Kahne
A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature 625 (7995) (2024)
Jiankun Lyu, Nicholas J Kapolka, Ryan Gumpper, Assaf Alon, Liang Wang, Manish Kumar Jain, Ximena Barros-Álvarez, Kensuke Sakamoto, Yoojoong Kim, Jeffrey F DiBerto, Kuglae Kim, Isabella S Glenn, Tia A Tummino, Sijie Huang, John J Irwin, Olga O Tarkhanova, Yurii S Moroz, Georgios Skiniotis, Andrew C Kruse, Brian K Shoichet, Bryan L Roth
AlphaFold2 structures guide prospective ligand discovery. Science (New York, N.Y.) 384 (6702) (2024)
Sarah C Erlandson, Jialu Wang, Haoran Jiang, James Osei-Owusu, Howard A Rockman, Andrew C Kruse
Engineering and Characterization of a Long-Half-Life Relaxin Receptor RXFP1 Agonist. Molecular pharmaceutics 21 (9) (2024)
Jiankun Lyu, Nicholas J Kapolka, Ryan Gumpper, Assaf Alon, Liang Wang, Manish Kumar Jain, Ximena Barros-Álvarez, Kensuke Sakamoto, Yoojoong Kim, Jeffrey F DiBerto, Kuglae Kim, Isabella S Glenn, Tia A Tummino, Sijie Huang, John J Irwin, Olga O Tarkhanova, Yurii S Moroz, Georgios Skiniotis, Andrew C Kruse, Brian K Shoichet, Bryan L Roth
AlphaFold2 structures guide prospective ligand discovery. Science (New York, N.Y.) 384 (6702) (2024)
Karanbir S Pahil, Morgan S A Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek, Fabian Dey, Dieter Muri, Remo Baettig, Michael Lobritz, Kenneth A Bradley, Andrew C Kruse, Daniel E Kahne
A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature 625 (7995) (2024)
Karanbir S Pahil, Morgan S A Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek, Fabian Dey, Dieter Muri, Remo Baettig, Michael Lobritz, Kenneth A Bradley, Andrew C Kruse, Daniel E Kahne
A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature 625 (7995) (2024)
Karanbir S Pahil, Morgan S A Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek, Fabian Dey, Dieter Muri, Remo Baettig, Michael Lobritz, Kenneth A Bradley, Andrew C Kruse, Daniel E Kahne
A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature 625 (7995) (2024)
Karanbir S Pahil, Morgan S A Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek, Fabian Dey, Dieter Muri, Remo Baettig, Michael Lobritz, Kenneth A Bradley, Andrew C Kruse, Daniel E Kahne
A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature 625 (7995) (2024)
Karanbir S Pahil, Morgan S A Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek, Fabian Dey, Dieter Muri, Remo Baettig, Michael Lobritz, Kenneth A Bradley, Andrew C Kruse, Daniel E Kahne
Author Correction: A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature (2024)
Meredith A Skiba, Sarah M Sterling, Shaun Rawson, Shuhao Zhang, Huixin Xu, Haoran Jiang, Genevieve R Nemeth, Morgan S A Gilman, Joseph D Hurley, Peng-Xiang Shen, Dean P Staus, Jihee Kim, Conor McMahon, Maria K Lehtinen, Howard A Rockman, Patrick Barth, Laura M Wingler, Andrew C Kruse
Antibodies expand the scope of angiotensin receptor pharmacology. Nature chemical biology (2024)
Karanbir S Pahil, Morgan S A Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek, Fabian Dey, Dieter Muri, Remo Baettig, Michael Lobritz, Kenneth A Bradley, Andrew C Kruse, Daniel E Kahne
A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature (2024)
Karanbir S Pahil, Morgan S A Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek, Fabian Dey, Dieter Muri, Remo Baettig, Michael Lobritz, Kenneth A Bradley, Andrew C Kruse, Daniel E Kahne
A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature (2024)
Karanbir S Pahil, Morgan S A Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek, Fabian Dey, Dieter Muri, Remo Baettig, Michael Lobritz, Kenneth A Bradley, Andrew C Kruse, Daniel E Kahne
A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature 625 (7995) (2024)
Karanbir S Pahil, Morgan S A Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek, Fabian Dey, Dieter Muri, Remo Baettig, Michael Lobritz, Kenneth A Bradley, Andrew C Kruse, Daniel E Kahne
A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature 625 (7995) (2024)
Karanbir S Pahil, Morgan S A Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek, Fabian Dey, Dieter Muri, Remo Baettig, Michael Lobritz, Kenneth A Bradley, Andrew C Kruse, Daniel E Kahne
Author Correction: A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature (2024)
Jeffrey S Smith, Ari S Hilibrand, Meredith A Skiba, Andrew N Dates, Victor G Calvillo-Miranda, Andrew C Kruse
The M3 Muscarinic Acetylcholine Receptor Can Signal through Multiple G Protein Families. Molecular pharmacology 105 (6) (2024)
Karanbir S Pahil, Morgan S A Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek, Fabian Dey, Dieter Muri, Remo Baettig, Michael Lobritz, Kenneth A Bradley, Andrew C Kruse, Daniel E Kahne
A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature 625 (7995) (2024)
Meredith A Skiba, Sarah M Sterling, Shaun Rawson, Shuhao Zhang, Huixin Xu, Haoran Jiang, Genevieve R Nemeth, Morgan S A Gilman, Joseph D Hurley, Peng-Xiang Shen, Dean P Staus, Jihee Kim, Conor McMahon, Maria K Lehtinen, Howard A Rockman, Patrick Barth, Laura M Wingler, Andrew C Kruse
Antibodies expand the scope of angiotensin receptor pharmacology. Nature chemical biology (2024)
Jiankun Lyu, Nicholas J Kapolka, Ryan Gumpper, Assaf Alon, Liang Wang, Manish Kumar Jain, Ximena Barros-Álvarez, Kensuke Sakamoto, Yoojoong Kim, Jeffrey F DiBerto, Kuglae Kim, Isabella S Glenn, Tia A Tummino, Sijie Huang, John J Irwin, Olga O Tarkhanova, Yurii S Moroz, Georgios Skiniotis, Andrew C Kruse, Brian K Shoichet, Bryan L Roth
AlphaFold2 structures guide prospective ligand discovery. Science (New York, N.Y.) (2024)
Karanbir S Pahil, Morgan S A Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek, Fabian Dey, Dieter Muri, Remo Baettig, Michael Lobritz, Kenneth A Bradley, Andrew C Kruse, Daniel E Kahne
A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature 625 (7995) (2024)
Karanbir S Pahil, Morgan S A Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek, Fabian Dey, Dieter Muri, Remo Baettig, Michael Lobritz, Kenneth A Bradley, Andrew C Kruse, Daniel E Kahne
A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature 625 (7995) (2024)
Jiankun Lyu, Nicholas J Kapolka, Ryan Gumpper, Assaf Alon, Liang Wang, Manish Kumar Jain, Ximena Barros-Álvarez, Kensuke Sakamoto, Yoojoong Kim, Jeffrey F DiBerto, Kuglae Kim, Isabella S Glenn, Tia A Tummino, Sijie Huang, John J Irwin, Olga O Tarkhanova, Yurii S Moroz, Georgios Skiniotis, Andrew C Kruse, Brian K Shoichet, Bryan L Roth
AlphaFold2 structures guide prospective ligand discovery. Science (New York, N.Y.) 384 (6702) (2024)
Jeffrey S Smith, Ari S Hilibrand, Meredith A Skiba, Andrew N Dates, Victor G Calvillo-Miranda, Andrew C Kruse
The M3 Muscarinic Acetylcholine Receptor Can Signal through Multiple G Protein Families. Molecular pharmacology 105 (6) (2024)
Karanbir S Pahil, Morgan S A Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek, Fabian Dey, Dieter Muri, Remo Baettig, Michael Lobritz, Kenneth A Bradley, Andrew C Kruse, Daniel E Kahne
A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature (2024)
Meredith A Skiba, Sarah M Sterling, Shaun Rawson, Shuhao Zhang, Huixin Xu, Haoran Jiang, Genevieve R Nemeth, Morgan S A Gilman, Joseph D Hurley, Peng-Xiang Shen, Dean P Staus, Jihee Kim, Conor McMahon, Maria K Lehtinen, Howard A Rockman, Patrick Barth, Laura M Wingler, Andrew C Kruse
Antibodies expand the scope of angiotensin receptor pharmacology. Nature chemical biology (2024)
Karanbir S Pahil, Morgan S A Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek, Fabian Dey, Dieter Muri, Remo Baettig, Michael Lobritz, Kenneth A Bradley, Andrew C Kruse, Daniel E Kahne
A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature 625 (7995) (2024)
Jeffrey S Smith, Ari S Hilibrand, Meredith A Skiba, Andrew N Dates, Victor G Calvillo-Miranda, Andrew C Kruse
The M3 muscarinic acetylcholine receptor can signal through multiple G protein families . Molecular pharmacology (2024)
Karanbir S Pahil, Morgan S A Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek, Fabian Dey, Dieter Muri, Remo Baettig, Michael Lobritz, Kenneth A Bradley, Andrew C Kruse, Daniel E Kahne
A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature 625 (7995) (2024)
Jiankun Lyu, Nicholas J Kapolka, Ryan Gumpper, Assaf Alon, Liang Wang, Manish Kumar Jain, Ximena Barros-Álvarez, Kensuke Sakamoto, Yoojoong Kim, Jeffrey F DiBerto, Kuglae Kim, Isabella S Glenn, Tia A Tummino, Sijie Huang, John J Irwin, Olga O Tarkhanova, Yurii S Moroz, Georgios Skiniotis, Andrew C Kruse, Brian K Shoichet, Bryan L Roth
AlphaFold2 structures guide prospective ligand discovery. Science (New York, N.Y.) 384 (6702) (2024)
Karanbir S Pahil, Morgan S A Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek, Fabian Dey, Dieter Muri, Remo Baettig, Michael Lobritz, Kenneth A Bradley, Andrew C Kruse, Daniel E Kahne
A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature (2024)
Jeffrey S Smith, Ari S Hilibrand, Meredith A Skiba, Andrew N Dates, Victor G Calvillo-Miranda, Andrew C Kruse
The M3 Muscarinic Acetylcholine Receptor Can Signal through Multiple G Protein Families. Molecular pharmacology 105 (6) (2024)
Jiankun Lyu, Nicholas J Kapolka, Ryan Gumpper, Assaf Alon, Liang Wang, Manish Kumar Jain, Ximena Barros-Álvarez, Kensuke Sakamoto, Yoojoong Kim, Jeffrey F DiBerto, Kuglae Kim, Isabella S Glenn, Tia A Tummino, Sijie Huang, John J Irwin, Olga O Tarkhanova, Yurii S Moroz, Georgios Skiniotis, Andrew C Kruse, Brian K Shoichet, Bryan L Roth
AlphaFold2 structures guide prospective ligand discovery. Science (New York, N.Y.) (2024)
Karanbir S Pahil, Morgan S A Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek, Fabian Dey, Dieter Muri, Remo Baettig, Michael Lobritz, Kenneth A Bradley, Andrew C Kruse, Daniel E Kahne
Author Correction: A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature (2024)
Karanbir S Pahil, Morgan S A Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek, Fabian Dey, Dieter Muri, Remo Baettig, Michael Lobritz, Kenneth A Bradley, Andrew C Kruse, Daniel E Kahne
A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature 625 (7995) (2024)
Karanbir S Pahil, Morgan S A Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek, Fabian Dey, Dieter Muri, Remo Baettig, Michael Lobritz, Kenneth A Bradley, Andrew C Kruse, Daniel E Kahne
A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature 625 (7995) (2024)
Meredith A Skiba, Sarah M Sterling, Shaun Rawson, Shuhao Zhang, Huixin Xu, Haoran Jiang, Genevieve R Nemeth, Morgan S A Gilman, Joseph D Hurley, Peng-Xiang Shen, Dean P Staus, Jihee Kim, Conor McMahon, Maria K Lehtinen, Howard A Rockman, Patrick Barth, Laura M Wingler, Andrew C Kruse
Antibodies expand the scope of angiotensin receptor pharmacology. Nature chemical biology (2024)
Yongqiang Gao, Jeremy D Amon, Lior Artzi, Fernando H Ramírez-Guadiana, Kelly P Brock, Joshua C Cofsky, Deborah S Marks, Andrew C Kruse, David Z Rudner
Bacterial spore germination receptors are nutrient-gated ion channels. Science (New York, N.Y.) 380 (6643) (2023)
Sarah C Erlandson, Shaun Rawson, James Osei-Owusu, Kelly P Brock, Xinyue Liu, Joao A Paulo, Julian Mintseris, Steven P Gygi, Debora S Marks, Xiaojing Cong, Andrew C Kruse
The relaxin receptor RXFP1 signals through a mechanism of autoinhibition. Nature chemical biology (2023)
Sarah C Erlandson, Shaun Rawson, James Osei-Owusu, Kelly P Brock, Xinyue Liu, Joao A Paulo, Julian Mintseris, Steven P Gygi, Debora S Marks, Xiaojing Cong, Andrew C Kruse
The relaxin receptor RXFP1 signals through a mechanism of autoinhibition. Nature chemical biology (2023)
Yongqiang Gao, Jeremy D Amon, Lior Artzi, Fernando H Ramírez-Guadiana, Kelly P Brock, Joshua C Cofsky, Deborah S Marks, Andrew C Kruse, David Z Rudner
Bacterial spore germination receptors are nutrient-gated ion channels. Science (New York, N.Y.) 380 (6643) (2023)
Meredith A Skiba, Sarah M Sterling, Shaun Rawson, Morgan S A Gilman, Huixin Xu, Genevieve R Nemeth, Joseph D Hurley, Pengxiang Shen, Dean P Staus, Jihee Kim, Conor McMahon, Maria K Lehtinen, Laura M Wingler, Andrew C Kruse
Antibodies Expand the Scope of Angiotensin Receptor Pharmacology. bioRxiv : the preprint server for biology (2023)
Yongqiang Gao, Jeremy D Amon, Lior Artzi, Fernando H Ramírez-Guadiana, Kelly P Brock, Joshua C Cofsky, Deborah S Marks, Andrew C Kruse, David Z Rudner
Bacterial spore germination receptors are nutrient-gated ion channels. Science (New York, N.Y.) 380 (6643) (2023)
Sarah C Erlandson, Shaun Rawson, James Osei-Owusu, Kelly P Brock, Xinyue Liu, Joao A Paulo, Julian Mintseris, Steven P Gygi, Debora S Marks, Xiaojing Cong, Andrew C Kruse
The relaxin receptor RXFP1 signals through a mechanism of autoinhibition. Nature chemical biology (2023)
Yongqiang Gao, Jeremy D Amon, Lior Artzi, Fernando H Ramírez-Guadiana, Kelly P Brock, Joshua C Cofsky, Deborah S Marks, Andrew C Kruse, David Z Rudner
Bacterial spore germination receptors are nutrient-gated ion channels. Science (New York, N.Y.) 380 (6643) (2023)
Yongqiang Gao, Jeremy D Amon, Lior Artzi, Fernando H Ramírez-Guadiana, Kelly P Brock, Joshua C Cofsky, Deborah S Marks, Andrew C Kruse, David Z Rudner
Bacterial spore germination receptors are nutrient-gated ion channels. Science (New York, N.Y.) 380 (6643) (2023)
Katherine J Susa, Gary A Bradshaw, Robyn J Eisert, Charlotte M Schilling, Marian Kalocsay, Stephen C Blacklow, Andrew C Kruse
A Spatiotemporal Map of Co-Receptor Signaling Networks Underlying B Cell Activation. bioRxiv : the preprint server for biology (2023)
Irina Shlosman, Elayne M Fivenson, Morgan S A Gilman, Tyler A Sisley, Suzanne Walker, Thomas G Bernhardt, Andrew C Kruse, Joseph John Loparo
Allosteric activation of cell wall synthesis during bacterial growth. Nature communications 14 (1) (2023)
Sarah C Erlandson, Shaun Rawson, James Osei-Owusu, Kelly P Brock, Xinyue Liu, Joao A Paulo, Julian Mintseris, Steven P Gygi, Debora S Marks, Xiaojing Cong, Andrew C Kruse
The relaxin receptor RXFP1 signals through a mechanism of autoinhibition. Nature chemical biology (2023)
Julia E Page, Meredith A Skiba, Truc Do, Andrew C Kruse, Suzanne Walker
Metal cofactor stabilization by a partner protein is a widespread strategy employed for amidase activation. Proceedings of the National Academy of Sciences of the United States of America 119 (26) (2022)
Edward P Harvey, Jung-Eun Shin, Meredith A Skiba, Genevieve R Nemeth, Joseph D Hurley, Alon Wellner, Ada Y Shaw, Victor G Miranda, Joseph K Min, Chang C Liu, Debora S Marks, Andrew C Kruse
An in silico method to assess antibody fragment polyreactivity. Nature communications 13 (1) (2022)
Jung-Eun Shin, Adam J Riesselman, Aaron W Kollasch, Conor McMahon, Elana Simon, Chris Sander, Aashish Manglik, Andrew C Kruse, Debora S Marks
Protein design and variant prediction using autoregressive generative models. Nature communications 12 (1) (2021)
Tia A Tummino, Veronica V Rezelj, Benoit Fischer, Audrey Fischer, Matthew J O'Meara, Blandine Monel, Thomas Vallet, Ziyang Zhang, Assaf Alon, Henry R O'Donnell, Jiankun Lyu, Heiko Schadt, Kris M White, Nevan J Krogan, Laszlo Urban, Kevan M Shokat, Andrew C Kruse, Adolfo García-Sastre, Olivier Schwartz, Francesca Moretti, Marco Vignuzzi, Francois Pognan, Brian K Shoichet
Phospholipidosis is a shared mechanism underlying the in vitro antiviral activity of many repurposed drugs against SARS-CoV-2. bioRxiv : the preprint server for biology (2021)
Lior Artzi, Assaf Alon, Kelly P Brock, Anna G Green, Amy Tam, Fernando H Ramírez-Guadiana, Debora Marks, Andrew C Kruse, David Z Rudner
Dormant spores sense amino acids through the B subunits of their germination receptors. Nature communications 12 (1) (2021)
Assaf Alon, Jiankun Lyu, Joao M Braz, Tia A Tummino, Veronica Craik, Matthew J O'Meara, Chase M Webb, Dmytro S Radchenko, Yurii S Moroz, Xi-Ping Huang, Yong-Feng Liu, Bryan L Roth, John J Irwin, Allan I Basbaum, Brian K Shoichet, Andrew C Kruse
Structures of the σ2 receptor enable docking for bioactive ligand discovery. Nature (2021)
Alon Wellner, Conor McMahon, Morgan S A Gilman, Jonathan R Clements, Sarah A Clark, Kianna M Nguyen, Ming H Ho, Vincent J Hu, Jung-Eun Shin, Jared Feldman, Blake M Hauser, Timothy M Caradonna, Laura M Wingler, Aaron G Schmidt, Debora S Marks, Jonathan Abraham, Andrew C Kruse, Chang C Liu
Rapid generation of potent antibodies by autonomous hypermutation in yeast. Nature chemical biology 17 (10) (2021)
Tia A Tummino, Veronica V Rezelj, Benoit Fischer, Audrey Fischer, Matthew J O'Meara, Blandine Monel, Thomas Vallet, Kris M White, Ziyang Zhang, Assaf Alon, Heiko Schadt, Henry R Oâ Donnell, Jiankun Lyu, Romel Rosales, Briana L McGovern, Raveen Rathnasinghe, Sonia Jangra, Michael Schotsaert, Jean-René Galarneau, Nevan J Krogan, Laszlo Urban, Kevan M Shokat, Andrew C Kruse, Adolfo García-Sastre, Olivier Schwartz, Francesca Moretti, Marco Vignuzzi, Francois Pognan, Brian K Shoichet
Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2. Science (New York, N.Y.) 373 (6554) (2021)
Katherine J Susa, Shaun Rawson, Andrew C Kruse, Stephen C Blacklow
Cryo-EM structure of the B cell co-receptor CD19 bound to the tetraspanin CD81. Science (New York, N.Y.) 371 (6526) (2021)
Conor McMahon, Dean P Staus, Laura M Wingler, Jialu Wang, Meredith A Skiba, Matthias Elgeti, Wayne L Hubbell, Howard A Rockman, Andrew C Kruse, Robert J Lefkowitz
Synthetic nanobodies as angiotensin receptor blockers. Proceedings of the National Academy of Sciences of the United States of America 117 (33) (2020)
Megan Sjodt, Patricia D A Rohs, Morgan S A Gilman, Sarah C Erlandson, Sanduo Zheng, Anna G Green, Kelly P Brock, Atsushi Taguchi, Daniel Kahne, Suzanne Walker, Debora S Marks, David Z Rudner, Thomas G Bernhardt, Andrew C Kruse
Structural coordination of polymerization and crosslinking by a SEDS-bPBP peptidoglycan synthase complex. Nature microbiology 5 (6) (2020)
Alon Wellner, Conor McMahon, Morgan S A Gilman, Jonathan R Clements, Sarah Clark, Kianna M Nguyen, Ming H Ho, Jung-Eun Shin, Jared Feldman, Blake M Hauser, Timothy M Caradonna, Laura M Wingler, Aaron G Schmidt, Debora S Marks, Jonathan Abraham, Andrew C Kruse, Chang C Liu
Rapid generation of potent antibodies by autonomous hypermutation in yeast. bioRxiv : the preprint server for biology (2020)
Laura M Wingler, Meredith A Skiba, Conor McMahon, Dean P Staus, Alissa L W Kleinhenz, Carl-Mikael Suomivuori, Naomi R Latorraca, Ron O Dror, Robert J Lefkowitz, Andrew C Kruse
Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR. Science (New York, N.Y.) 367 (6480) (2020)
Katherine J Susa, Tom Cm Seegar, Stephen C Blacklow, Andrew C Kruse
A dynamic interaction between CD19 and the tetraspanin CD81 controls B cell co-receptor trafficking. eLife 9 (2020)
Chunxiao Yu, Longfei Wang, R Grant Rowe, Areum Han, Wanying Ji, Conor McMahon, Alexander S Baier, Yu-Chung Huang, William Marion, Daniel S Pearson, Andrew C Kruse, George Q Daley, Hao Wu, Piotr Sliz
A nanobody targeting the LIN28:let-7 interaction fragment of TUT4 blocks uridylation of let-7. Proceedings of the National Academy of Sciences of the United States of America 117 (9) (2020)
Carl-Mikael Suomivuori, Naomi R Latorraca, Laura M Wingler, Stephan Eismann, Matthew C King, Alissa L W Kleinhenz, Meredith A Skiba, Dean P Staus, Andrew C Kruse, Robert J Lefkowitz, Ron O Dror
Molecular mechanism of biased signaling in a prototypical G protein-coupled receptor. Science (New York, N.Y.) 367 (6480) (2020)
Sanduo Zheng, Andrew C Kruse
Solving a specificity mystery. eLife 8 (2019)
Atsushi Taguchi, Michael A Welsh, Lindsey S Marmont, Wonsik Lee, Megan Sjodt, Andrew C Kruse, Daniel Kahne, Thomas G Bernhardt, Suzanne Walker
FtsW is a peptidoglycan polymerase that is functional only in complex with its cognate penicillin-binding protein. Nature microbiology 4 (4) (2019)
Conor McMahon, Alexander S Baier, Roberta Pascolutti, Marcin Wegrecki, Sanduo Zheng, Janice X Ong, Sarah C Erlandson, Daniel Hilger, Søren G F Rasmussen, Aaron M Ring, Aashish Manglik, Andrew C Kruse
Yeast surface display platform for rapid discovery of conformationally selective nanobodies. Nature structural & molecular biology 25 (3) (2018)
Hayden R Schmidt, Robin M Betz, Ron O Dror, Andrew C Kruse
Structural basis for σ1 receptor ligand recognition. Nature structural & molecular biology 25 (10) (2018)
Patricia D A Rohs, Jackson Buss, Sue Im Sim, Georgia R Squyres, Veerasak Srisuknimit, Mandy Smith, Hongbaek Cho, Megan Sjodt, Andrew C Kruse, Ethan C Garner, Suzanne Walker, Daniel E Kahne, Thomas G Bernhardt
A central role for PBP2 in the activation of peptidoglycan polymerization by the bacterial cell elongation machinery. PLoS genetics 14 (10) (2018)
Sanduo Zheng, Lok-To Sham, Frederick A Rubino, Kelly P Brock, William P Robins, John J Mekalanos, Debora S Marks, Thomas G Bernhardt, Andrew C Kruse
Structure and mutagenic analysis of the lipid II flippase MurJ from Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America 115 (26) (2018)
Dean P Staus, Laura M Wingler, Minjung Choi, Biswaranjan Pani, Aashish Manglik, Andrew C Kruse, Robert J Lefkowitz
Sortase ligation enables homogeneous GPCR phosphorylation to reveal diversity in β-arrestin coupling. Proceedings of the National Academy of Sciences of the United States of America 115 (15) (2018)
Fernando H Ramírez-Guadiana, Christopher D A Rodrigues, Kathleen A Marquis, Nathalie Campo, Rocío Del Carmen Barajas-Ornelas, Kelly Brock, Debora S Marks, Andrew C Kruse, David Z Rudner
Evidence that regulation of intramembrane proteolysis is mediated by substrate gating during sporulation in Bacillus subtilis. PLoS genetics 14 (11) (2018)
Magdalena Korczynska, Mary J Clark, Celine Valant, Jun Xu, Ee Von Moo, Sabine Albold, Dahlia R Weiss, Hayarpi Torosyan, Weijiao Huang, Andrew C Kruse, Brent R Lyda, Lauren T May, Jo-Anne Baltos, Patrick M Sexton, Brian K Kobilka, Arthur Christopoulos, Brian K Shoichet, Roger K Sunahara
Structure-based discovery of selective positive allosteric modulators of antagonists for the M2 muscarinic acetylcholine receptor. Proceedings of the National Academy of Sciences of the United States of America 115 (10) (2018)
Assaf Alon, Hayden R Schmidt, Michael D Wood, James J Sahn, Stephen F Martin, Andrew C Kruse
Identification of the gene that codes for the σ2 receptor. Proceedings of the National Academy of Sciences of the United States of America 114 (27) (2017)
Aashish Manglik, Andrew C Kruse
Structural Basis for G Protein-Coupled Receptor Activation. Biochemistry 56 (42) (2017)

Andrew C Kruse.css-eqlu8i{font-size:small;padding-left:4px;} (Andrew Kruse)

Publication Activity (10 Years)

Top Topics

Top Venues

Andrew C Kruse (Andrew Kruse)