Nina Isoherranen

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 42

Top Topics

Top Venues

Drug metabolism and disposition: the biological fate of chemicals

Molecular pharmacology

bioRxiv : the preprint server for biology

This page only lists publications with an associated author ORCID identifier.

Publications

King Clyde B Yabut, Alice Martynova, Abhinav Nath, Benjamin P Zercher, Matthew F Bush, Nina Isoherranen
Drugs Form Ternary Complexes with Human Liver Fatty Acid Binding Protein 1 (FABP1) and FABP1 Binding Alters Drug Metabolism. Molecular pharmacology 105 (6) (2024)
King Clyde B Yabut, Alice Martynova, Abhinav Nath, Benjamin P Zercher, Matthew F Bush, Nina Isoherranen
Drugs Form Ternary Complexes with Human Liver Fatty Acid Binding Protein (FABP1) and FABP1 Binding Alters Drug Metabolism. bioRxiv : the preprint server for biology (2024)
King Clyde B Yabut, Alice Martynova, Abhinav Nath, Benjamin P Zercher, Matthew F Bush, Nina Isoherranen
Drugs Form Ternary Complexes with Human Liver Fatty Acid Binding Protein 1 (FABP1) and FABP1 Binding Alters Drug Metabolism. Molecular pharmacology 105 (6) (2024)
Lindsay C Czuba, Nina Isoherranen
LX-2 Stellate Cells Are a Model System for Investigating the Regulation of Hepatic Vitamin A Metabolism and Respond to Tumor Necrosis Factor α and Interleukin 1 β . Drug metabolism and disposition: the biological fate of chemicals 52 (5) (2024)
Lindsay C Czuba, Nina Isoherranen
LX-2 Stellate Cells Are a Model System for Investigating the Regulation of Hepatic Vitamin A Metabolism and Respond to Tumor Necrosis Factor α and Interleukin 1 β . Drug metabolism and disposition: the biological fate of chemicals 52 (5) (2024)
King Clyde B Yabut, Alice Martynova, Abhinav Nath, Benjamin P Zercher, Matthew F Bush, Nina Isoherranen
Drugs Form Ternary Complexes with Human Liver Fatty Acid Binding Protein (FABP1) and FABP1 Binding Alters Drug Metabolism. bioRxiv : the preprint server for biology (2024)
King Clyde B Yabut, Alice Martynova, Abhinav Nath, Benjamin P Zercher, Matthew F Bush, Nina Isoherranen
Drugs Form Ternary Complexes with Human Liver Fatty Acid Binding Protein (FABP1) and FABP1 Binding Alters Drug Metabolism. bioRxiv : the preprint server for biology (2024)
King Clyde B Yabut, Alice Martynova, Abhinav Nath, Benjamin P Zercher, Matthew F Bush, Nina Isoherranen
Drugs Form Ternary Complexes with Human Liver Fatty Acid Binding Protein (FABP1) and FABP1 Binding Alters Drug Metabolism. bioRxiv : the preprint server for biology (2024)
Lindsay C Czuba, Nina Isoherranen
LX-2 Stellate Cells Are a Model System for Investigating the Regulation of Hepatic Vitamin A Metabolism and Respond to Tumor Necrosis Factor α and Interleukin 1 β . Drug metabolism and disposition: the biological fate of chemicals 52 (5) (2024)
King Clyde B Yabut, Alice Martynova, Abhinav Nath, Benjamin P Zercher, Matthew F Bush, Nina Isoherranen
Drugs Form Ternary Complexes with Human Liver Fatty Acid Binding Protein 1 (FABP1) and FABP1 Binding Alters Drug Metabolism. Molecular pharmacology 105 (6) (2024)
King Clyde B Yabut, Alice Martynova, Abhinav Nath, Benjamin P Zercher, Matthew F Bush, Nina Isoherranen
Drugs Form Ternary Complexes with Human Liver Fatty Acid Binding Protein (FABP1) and FABP1 Binding Alters Drug Metabolism. Molecular pharmacology (2024)
King Clyde B Yabut, Alice Martynova, Abhinav Nath, Benjamin P Zercher, Matthew F Bush, Nina Isoherranen
Drugs Form Ternary Complexes with Human Liver Fatty Acid Binding Protein 1 (FABP1) and FABP1 Binding Alters Drug Metabolism. Molecular pharmacology 105 (6) (2024)
King Clyde B Yabut, Alice Martynova, Abhinav Nath, Benjamin P Zercher, Matthew F Bush, Nina Isoherranen
Drugs Form Ternary Complexes with Human Liver Fatty Acid Binding Protein (FABP1) and FABP1 Binding Alters Drug Metabolism. Molecular pharmacology (2024)
Nina Isoherranen
Physiologically Based Pharmacokinetic (PBPK) Modeling of small molecules: How Much Progress Have We Made? Drug metabolism and disposition: the biological fate of chemicals (2024)
Lindsay C Czuba, Nina Isoherranen
LX-2 Stellate Cells Are a Model System for Investigating the Regulation of Hepatic Vitamin A Metabolism and Respond to Tumor Necrosis Factor α and Interleukin 1 β . Drug metabolism and disposition: the biological fate of chemicals 52 (5) (2024)
King Clyde B Yabut, Alice Martynova, Abhinav Nath, Benjamin P Zercher, Matthew F Bush, Nina Isoherranen
Drugs Form Ternary Complexes with Human Liver Fatty Acid Binding Protein 1 (FABP1) and FABP1 Binding Alters Drug Metabolism. Molecular pharmacology 105 (6) (2024)
Lindsay C Czuba, Nina Isoherranen
LX-2 stellate cells are a model system for investigating the regulation of hepatic vitamin A metabolism and respond to tumor necrosis factor alpha and interleukin 1 beta. Drug metabolism and disposition: the biological fate of chemicals (2024)
Ogochukwu Amaeze, Nina Isoherranen, Sara Shum
The ADME characteristics of siRNA therapeutics and the opportunity to predict disposition in pregnant women. Drug metabolism and disposition: the biological fate of chemicals (2024)
King Clyde B Yabut, Alice Martynova, Abhinav Nath, Benjamin P Zercher, Matthew F Bush, Nina Isoherranen
Drugs Form Ternary Complexes with Human Liver Fatty Acid Binding Protein (FABP1) and FABP1 Binding Alters Drug Metabolism. bioRxiv : the preprint server for biology (2024)
Lindsay C Czuba, Nina Isoherranen
LX-2 Stellate Cells Are a Model System for Investigating the Regulation of Hepatic Vitamin A Metabolism and Respond to Tumor Necrosis Factor α and Interleukin 1 β . Drug metabolism and disposition: the biological fate of chemicals 52 (5) (2024)
Nathan Alade, Abhinav Nath, Nina Isoherranen, Kenneth E Thummel
The Utility of Mixed-Effects Models in the Evaluation of Complex Genomic Traits In Vitro. Drug metabolism and disposition: the biological fate of chemicals (2023)
Luke F Enthoven, Yuanyuan Shi, Emily E Fay, Sue Moreni, Jennie Mao, Emma M Honeyman, Chase K Smith, Dale Whittington, Susan E Brockerhoff, Nina Isoherranen, Rheem A Totah, Mary F Hebert
The Effects of Pregnancy on Amino Acid Levels and Nitrogen Disposition. Metabolites 13 (2) (2023)
Jessica L Beers, Aurora K Authement, Nina Isoherranen, Klarissa D Jackson
Cytosolic Enzymes Generate Cannabinoid Metabolites 7-Carboxycannabidiol and 11-Nor-9-carboxytetrahydrocannabinol. ACS medicinal chemistry letters 14 (5) (2023)
Luke F Enthoven, Yuanyuan Shi, Emily E Fay, Sue Moreni, Jennie Mao, Emma M Honeyman, Chase K Smith, Dale Whittington, Susan E Brockerhoff, Nina Isoherranen, Rheem A Totah, Mary F Hebert
The Effects of Pregnancy on Amino Acid Levels and Nitrogen Disposition. Metabolites 13 (2) (2023)
Luke F Enthoven, Yuanyuan Shi, Emily E Fay, Sue Moreni, Jennie Mao, Emma M Honeyman, Chase K Smith, Dale Whittington, Susan E Brockerhoff, Nina Isoherranen, Rheem A Totah, Mary F Hebert
The Effects of Pregnancy on Amino Acid Levels and Nitrogen Disposition. Metabolites 13 (2) (2023)
Michael L Granda, Weize Huang, Catherine K Yeung, Nina Isoherranen, Bryan Kestenbaum
Predicting Complex Kidney Drug Handling Using A Physiologically-Based Pharmacokinetic (PBPK) Model Informed By Biomarker-Estimated Secretory Clearance and Blood Flow. Clinical and translational science (2023)
King Clyde B Yabut, Nina Isoherranen
Impact of Intracellular Lipid Binding Proteins on Endogenous and Xenobiotics Ligand Metabolism and Disposition. Drug metabolism and disposition: the biological fate of chemicals (2023)
Luke F Enthoven, Yuanyuan Shi, Emily Fay, Agnes Kim, Sue Moreni, Jennie Mao, Nina Isoherranen, Rheem A Totah, Mary F Hebert
Effects of Pregnancy on Plasma Sphingolipids Using a Metabolomic and Quantitative Analysis Approach. Metabolites 13 (9) (2023)
Ogochukwu U Amaeze, Nina Isoherranen
Application of a physiologically based pharmacokinetic model to predict isoniazid disposition during pregnancy. Clinical and translational science (2023)
Jessica L Beers, Aurora K Authement, Nina Isoherranen, Klarissa D Jackson
Cytosolic Enzymes Generate Cannabinoid Metabolites 7-Carboxycannabidiol and 11-Nor-9-carboxytetrahydrocannabinol. ACS medicinal chemistry letters 14 (5) (2023)
Matthew A Walker, Hongye Chen, Aprajita S Yadav, Julia Ritterhoff, Outi Villet, Timothy S McMillen, Yuliang Wang, Hayley Purcell, Danijel Djukovic, Daniel Raftery, Nina Isoherranen, Rong Tian
Stimulates Short-Chain Dehydrogenase/Reductase Proteins to Alleviate Heart Failure Independent of Mitochondrial Protein Deacetylation. Circulation (2023)
Luke F Enthoven, Yuanyuan Shi, Emily E Fay, Sue Moreni, Jennie Mao, Emma M Honeyman, Chase K Smith, Dale Whittington, Susan E Brockerhoff, Nina Isoherranen, Rheem A Totah, Mary F Hebert
The Effects of Pregnancy on Amino Acid Levels and Nitrogen Disposition. Metabolites 13 (2) (2023)
Lindsay C Czuba, Karan Malhotra, Luke Enthoven, Emily E Fay, Sue L Moreni, Jennie Mao, Yuanyuan Shi, Weize Huang, Rheem A Totah, Nina Isoherranen, Mary F Hebert
CYP2D6 activity is correlated with changes in plasma concentrations of taurocholic acid during pregnancy and postpartum in CYP2D6 extensive metabolizers. Drug metabolism and disposition: the biological fate of chemicals (2023)
Aprajita S Yadav, Faith Stevison, Mika Kosaka, Susan Wong, Jane R Kenny, John K Amory, Nina Isoherranen
Isotretinoin and its Metabolites Alter mRNA of Multiple Enzyme and Transporter Genes In Vitro, but Downregulation of Organic Anion Transporting Polypeptide Does Not Translate to the Clinic. Drug metabolism and disposition: the biological fate of chemicals 50 (7) (2022)
Lindsay C Czuba, Emily E Fay, Jeffrey LaFrance, Chase K Smith, Sara Shum, Sue L Moreni, Jennie Mao, Nina Isoherranen, Mary F Hebert
Plasma Retinoid Concentrations Are Altered in Pregnant Women. Nutrients 14 (7) (2022)
King Clyde B Yabut, Nina Isoherranen
CRABPs Alter all-trans -Retinoic Acid Metabolism by CYP26A1 via Protein-Protein Interactions. Nutrients 14 (9) (2022)
Sara Shum, Nina Isoherranen
Human Fetal Liver Metabolism of Oxycodone Is Mediated by CYP3A7. The AAPS journal 23 (1) (2021)
Weize Huang, Lindsay C Czuba, Jennifer A Manuzak, Jeffrey N Martin, Peter W Hunt, Nichole R Klatt, Nina Isoherranen
Objective Identification of Cannabis Use Levels in Clinical Populations Is Critical for Detecting Pharmacological Outcomes. Cannabis and cannabinoid research (2021)
Weize Huang, Lindsay C Czuba, Nina Isoherranen
Mechanistic PBPK Modeling of Urine pH Effect on Renal and Systemic Disposition of Methamphetamine and Amphetamine. The Journal of pharmacology and experimental therapeutics 373 (3) (2020)
Weize Huang, Nina Isoherranen
Sampling Site Has a Critical Impact on Physiologically Based Pharmacokinetic Modeling. The Journal of pharmacology and experimental therapeutics 372 (1) (2019)
Kathi A Lefebvre, Betsy Jean Yakes, Elizabeth Frame, Preston Kendrick, Sara Shum, Nina Isoherranen, Bridget E Ferriss, Alison Robertson, Alicia Hendrix, David J Marcinek, Lynn Grattan
Discovery of a Potential Human Serum Biomarker for Chronic Seafood Toxin Exposure Using an SPR Biosensor. Toxins 11 (5) (2019)
Guo Zhong, Cathryn Hogarth, Jessica M Snyder, Laura Palau, Traci Topping, Weize Huang, Lindsay C Czuba, Jeffrey LaFrance, Gabriel Ghiaur, Nina Isoherranen
The retinoic acid hydroxylase Cyp26a1 has minor effects on postnatal vitamin A homeostasis, but is required for exogenous atRA clearance. The Journal of biological chemistry 294 (29) (2019)