Xuexiang Han

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 42

Top Topics

Epidermal Growth Factor Receptor

Top Venues

Nature communications

Nature biomedical engineering

Science translational medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Xuexiang Han, Mohamad-Gabriel Alameh, Ningqiang Gong, Lulu Xue, Majed Ghattas, Goutham Bojja, Junchao Xu, Gan Zhao, Claude C Warzecha, Marshall S Padilla, Rakan El-Mayta, Garima Dwivedi, Ying Xu, Andrew E Vaughan, James M Wilson, Drew Weissman, Michael J Mitchell
Fast and facile synthesis of amidine-incorporated degradable lipids for versatile mRNA delivery in vivo. Nature chemistry (2024)
Lulu Xue, Alex G Hamilton, Gan Zhao, Zebin Xiao, Rakan El-Mayta, Xuexiang Han, Ningqiang Gong, Xinhong Xiong, Junchao Xu, Christian G Figueroa-Espada, Sarah J Shepherd, Alvin J Mukalel, Mohamad Gabriel Alameh, Jiaxi Cui, Karin Wang, Andrew E Vaughan, Drew Weissman, Michael J Mitchell
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models. Nature communications 15 (1) (2024)
Lulu Xue, Alex G Hamilton, Gan Zhao, Zebin Xiao, Rakan El-Mayta, Xuexiang Han, Ningqiang Gong, Xinhong Xiong, Junchao Xu, Christian G Figueroa-Espada, Sarah J Shepherd, Alvin J Mukalel, Mohamad Gabriel Alameh, Jiaxi Cui, Karin Wang, Andrew E Vaughan, Drew Weissman, Michael J Mitchell
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models. Nature communications 15 (1) (2024)
Gan Zhao, Lulu Xue, Aaron I Weiner, Ningqiang Gong, Stephanie Adams-Tzivelekidis, Joanna Wong, Maria E Gentile, Ana N Nottingham, Maria C Basal, Susan M Lin, Terren K Niethamer, Joshua M Diamond, Christian A Bermudez, Edward Cantu, Xuexiang Han, Yaqi Cao, Mohamad Gabriel Alameh, Drew Weissman, Edward E Morrisey, Michael J Mitchell, Andrew E Vaughan
TGF-βR2 signaling coordinates pulmonary vascular repair after viral injury in mice and human tissue. Science translational medicine 16 (732) (2024)
Ningqiang Gong, Wenqun Zhong, Mohamad Gabriel Alameh, Xuexiang Han, Lulu Xue, Rakan El-Mayta, Gan Zhao, Andrew E Vaughan, Zhiyuan Qin, Fengyuan Xu, Alex G Hamilton, Dongyoon Kim, Junchao Xu, Junhyong Kim, Xucong Teng, Jinghong Li, Xing-Jie Liang, Drew Weissman, Wei Guo, Michael J Mitchell
Tumour-derived small extracellular vesicles act as a barrier to therapeutic nanoparticle delivery. Nature materials (2024)
Gan Zhao, Lulu Xue, Aaron I Weiner, Ningqiang Gong, Stephanie Adams-Tzivelekidis, Joanna Wong, Maria E Gentile, Ana N Nottingham, Maria C Basal, Susan M Lin, Terren K Niethamer, Joshua M Diamond, Christian A Bermudez, Edward Cantu, Xuexiang Han, Yaqi Cao, Mohamad Gabriel Alameh, Drew Weissman, Edward E Morrisey, Michael J Mitchell, Andrew E Vaughan
TGF-βR2 signaling coordinates pulmonary vascular repair after viral injury in mice and human tissue. Science translational medicine 16 (732) (2024)
Ningqiang Gong, Xuexiang Han, Lulu Xue, Margaret M Billingsley, Xisha Huang, Rakan El-Mayta, Jingya Qin, Neil C Sheppard, Carl H June, Michael J Mitchell
Small-molecule-mediated control of the anti-tumour activity and off-tumour toxicity of a supramolecular bispecific T cell engager. Nature biomedical engineering 8 (5) (2024)
Lulu Xue, Alex G Hamilton, Gan Zhao, Zebin Xiao, Rakan El-Mayta, Xuexiang Han, Ningqiang Gong, Xinhong Xiong, Junchao Xu, Christian G Figueroa-Espada, Sarah J Shepherd, Alvin J Mukalel, Mohamad Gabriel Alameh, Jiaxi Cui, Karin Wang, Andrew E Vaughan, Drew Weissman, Michael J Mitchell
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models. Nature communications 15 (1) (2024)
Ningqiang Gong, Xuexiang Han, Lulu Xue, Margaret M Billingsley, Xisha Huang, Rakan El-Mayta, Jingya Qin, Neil C Sheppard, Carl H June, Michael J Mitchell
Small-molecule-mediated control of the anti-tumour activity and off-tumour toxicity of a supramolecular bispecific T cell engager. Nature biomedical engineering (2024)
Gan Zhao, Lulu Xue, Aaron I Weiner, Ningqiang Gong, Stephanie Adams-Tzivelekidis, Joanna Wong, Maria E Gentile, Ana N Nottingham, Maria C Basal, Susan M Lin, Terren K Niethamer, Joshua M Diamond, Christian A Bermudez, Edward Cantu, Xuexiang Han, Yaqi Cao, Mohamad Gabriel Alameh, Drew Weissman, Edward E Morrisey, Michael J Mitchell, Andrew E Vaughan
TGF-βR2 signaling coordinates pulmonary vascular repair after viral injury in mice and human tissue. Science translational medicine 16 (732) (2024)
Ningqiang Gong, Xuexiang Han, Lulu Xue, Margaret M Billingsley, Xisha Huang, Rakan El-Mayta, Jingya Qin, Neil C Sheppard, Carl H June, Michael J Mitchell
Small-molecule-mediated control of the anti-tumour activity and off-tumour toxicity of a supramolecular bispecific T cell engager. Nature biomedical engineering (2024)
Xuexiang Han, Junchao Xu, Ying Xu, Mohamad Gabriel Alameh, Lulu Xue, Ningqiang Gong, Rakan El-Mayta, Rohan Palanki, Claude C Warzecha, Gan Zhao, Andrew E Vaughan, James M Wilson, Drew Weissman, Michael J Mitchell
In situ combinatorial synthesis of degradable branched lipidoids for systemic delivery of mRNA therapeutics and gene editors. Nature communications 15 (1) (2024)
Gan Zhao, Lulu Xue, Aaron I Weiner, Ningqiang Gong, Stephanie Adams-Tzivelekidis, Joanna Wong, Maria E Gentile, Ana N Nottingham, Maria C Basal, Susan M Lin, Terren K Niethamer, Joshua M Diamond, Christian A Bermudez, Edward Cantu, Xuexiang Han, Yaqi Cao, Mohamad Gabriel Alameh, Drew Weissman, Edward E Morrisey, Michael J Mitchell, Andrew E Vaughan
TGF-βR2 signaling coordinates pulmonary vascular repair after viral injury in mice and human tissue. Science translational medicine 16 (732) (2024)
Lulu Xue, Alex G Hamilton, Gan Zhao, Zebin Xiao, Rakan El-Mayta, Xuexiang Han, Ningqiang Gong, Xinhong Xiong, Junchao Xu, Christian G Figueroa-Espada, Sarah J Shepherd, Alvin J Mukalel, Mohamad Gabriel Alameh, Jiaxi Cui, Karin Wang, Andrew E Vaughan, Drew Weissman, Michael J Mitchell
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models. Nature communications 15 (1) (2024)
Gan Zhao, Lulu Xue, Aaron I Weiner, Ningqiang Gong, Stephanie Adams-Tzivelekidis, Joanna Wong, Maria E Gentile, Ana N Nottingham, Maria C Basal, Susan M Lin, Terren K Niethamer, Joshua M Diamond, Christian A Bermudez, Edward Cantu, Xuexiang Han, Yaqi Cao, Mohamad Gabriel Alameh, Drew Weissman, Edward E Morrisey, Michael J Mitchell, Andrew E Vaughan
TGF-βR2 signaling coordinates pulmonary vascular repair after viral injury in mice and human tissue. Science translational medicine 16 (732) (2024)
Lulu Xue, Alex G Hamilton, Gan Zhao, Zebin Xiao, Rakan El-Mayta, Xuexiang Han, Ningqiang Gong, Xinhong Xiong, Junchao Xu, Christian G Figueroa-Espada, Sarah J Shepherd, Alvin J Mukalel, Mohamad Gabriel Alameh, Jiaxi Cui, Karin Wang, Andrew E Vaughan, Drew Weissman, Michael J Mitchell
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models. Nature communications 15 (1) (2024)
Ningqiang Gong, Xuexiang Han, Lulu Xue, Margaret M Billingsley, Xisha Huang, Rakan El-Mayta, Jingya Qin, Neil C Sheppard, Carl H June, Michael J Mitchell
Small-molecule-mediated control of the anti-tumour activity and off-tumour toxicity of a supramolecular bispecific T cell engager. Nature biomedical engineering 8 (5) (2024)
Ningqiang Gong, Xuexiang Han, Lulu Xue, Margaret M Billingsley, Xisha Huang, Rakan El-Mayta, Jingya Qin, Neil C Sheppard, Carl H June, Michael J Mitchell
Author Correction: Small-molecule-mediated control of the anti-tumour activity and off-tumour toxicity of a supramolecular bispecific T cell engager. Nature biomedical engineering (2024)
Lulu Xue, Alex G Hamilton, Gan Zhao, Zebin Xiao, Rakan El-Mayta, Xuexiang Han, Ningqiang Gong, Xinhong Xiong, Junchao Xu, Christian G Figueroa-Espada, Sarah J Shepherd, Alvin J Mukalel, Mohamad Gabriel Alameh, Jiaxi Cui, Karin Wang, Andrew E Vaughan, Drew Weissman, Michael J Mitchell
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models. Nature communications 15 (1) (2024)
Gan Zhao, Lulu Xue, Aaron I Weiner, Ningqiang Gong, Stephanie Adams-Tzivelekidis, Joanna Wong, Maria E Gentile, Ana N Nottingham, Maria C Basal, Susan M Lin, Terren K Niethamer, Joshua M Diamond, Christian A Bermudez, Edward Cantu, Xuexiang Han, Yaqi Cao, Mohamad Gabriel Alameh, Drew Weissman, Edward E Morrisey, Michael J Mitchell, Andrew E Vaughan
TGF-βR2 signaling coordinates pulmonary vascular repair after viral injury in mice and human tissue. Science translational medicine 16 (732) (2024)
Lulu Xue, Alex G Hamilton, Gan Zhao, Zebin Xiao, Rakan El-Mayta, Xuexiang Han, Ningqiang Gong, Xinhong Xiong, Junchao Xu, Christian G Figueroa-Espada, Sarah J Shepherd, Alvin J Mukalel, Mohamad Gabriel Alameh, Jiaxi Cui, Karin Wang, Andrew E Vaughan, Drew Weissman, Michael J Mitchell
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models. Nature communications 15 (1) (2024)
Xuexiang Han, Junchao Xu, Ying Xu, Mohamad Gabriel Alameh, Lulu Xue, Ningqiang Gong, Rakan El-Mayta, Rohan Palanki, Claude C Warzecha, Gan Zhao, Andrew E Vaughan, James M Wilson, Drew Weissman, Michael J Mitchell
In situ combinatorial synthesis of degradable branched lipidoids for systemic delivery of mRNA therapeutics and gene editors. Nature communications 15 (1) (2024)
Xuexiang Han, Junchao Xu, Ying Xu, Mohamad Gabriel Alameh, Lulu Xue, Ningqiang Gong, Rakan El-Mayta, Rohan Palanki, Claude C Warzecha, Gan Zhao, Andrew E Vaughan, James M Wilson, Drew Weissman, Michael J Mitchell
In situ combinatorial synthesis of degradable branched lipidoids for systemic delivery of mRNA therapeutics and gene editors. Nature communications 15 (1) (2024)
Ningqiang Gong, Xuexiang Han, Lulu Xue, Margaret M Billingsley, Xisha Huang, Rakan El-Mayta, Jingya Qin, Neil C Sheppard, Carl H June, Michael J Mitchell
Small-molecule-mediated control of the anti-tumour activity and off-tumour toxicity of a supramolecular bispecific T cell engager. Nature biomedical engineering (2024)
Stefan R Torborg, Olivera Grbovic-Huezo, Anupriya Singhal, Matilda Holm, Katherine Wu, Xuexiang Han, Yu-Jui Ho, Caj Haglund, Michael J Mitchell, Scott W Lowe, Lukas E Dow, Kenneth L Pitter, Francisco J Sánchez Rivera, Andre Levchenko, Tuomas Tammela
Solid tumor growth depends on an intricate equilibrium of malignant cell states. bioRxiv : the preprint server for biology (2023)
Xuexiang Han, Ningqiang Gong, Lulu Xue, Margaret M Billingsley, Rakan El-Mayta, Sarah J Shepherd, Mohamad Gabriel Alameh, Drew Weissman, Michael J Mitchell
Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis. Nature communications 14 (1) (2023)
Xuexiang Han, Mohamad-Gabriel Alameh, Kamila Butowska, James J Knox, Kendall A Lundgreen, Majed Ghattas, Ningqiang Gong, Lulu Xue, Ying Xu, Marc Lavertu, Paul Bates, Junchao Xu, Guangjun Nie, Yi Zhong, Drew Weissman, Michael J Mitchell
Adjuvant lipidoid-substituted lipid nanoparticles augment the immunogenicity of SARS-CoV-2 mRNA vaccines. Nature nanotechnology (2023)
Xuexiang Han, Ningqiang Gong, Lulu Xue, Margaret M Billingsley, Rakan El-Mayta, Sarah J Shepherd, Mohamad Gabriel Alameh, Drew Weissman, Michael J Mitchell
Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis. Nature communications 14 (1) (2023)
Xuexiang Han, Ningqiang Gong, Lulu Xue, Margaret M Billingsley, Rakan El-Mayta, Sarah J Shepherd, Mohamad Gabriel Alameh, Drew Weissman, Michael J Mitchell
Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis. Nature communications 14 (1) (2023)
Ningqiang Gong, Xuexiang Han, Lulu Xue, Rakan El-Mayta, Ann E Metzloff, Margaret M Billingsley, Alex G Hamilton, Michael J Mitchell
In situ PEGylation of CAR T cells alleviates cytokine release syndrome and neurotoxicity. Nature materials (2023)
Xuexiang Han, Ningqiang Gong, Lulu Xue, Margaret M Billingsley, Rakan El-Mayta, Sarah J Shepherd, Mohamad Gabriel Alameh, Drew Weissman, Michael J Mitchell
Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis. Nature communications 14 (1) (2023)
Linhao You, Jing Wang, Tianqing Liu, Yinlong Zhang, Xuexiang Han, Ting Wang, Shanshan Guo, Tianyu Dong, Junchao Xu, Gregory J Anderson, Qiang Liu, Yan-Zhong Chang, Xin Lou, Guangjun Nie
Correction to Targeted Brain Delivery of Rabies Virus Glycoprotein 29-Modified Deferoxamine-Loaded Nanoparticles Reverses Functional Deficits in Parkinsonian Mice. ACS nano 16 (11) (2022)
Xuexiang Han, Keman Cheng, Ying Xu, Yazhou Wang, Huan Min, Yinlong Zhang, Xiao Zhao, Ruifang Zhao, Gregory J Anderson, Lei Ren, Guangjun Nie, Yiye Li
Modularly Designed Peptide Nanoprodrug Augments Antitumor Immunity of PD-L1 Checkpoint Blockade by Targeting Indoleamine 2,3-Dioxygenase. Journal of the American Chemical Society 142 (5) (2020)
Mohammad Taleb, Yanping Ding, Bin Wang, Na Yang, Xuexiang Han, Chong Du, Yingqiu Qi, Yinlong Zhang, Zeinab Farhadi Sabet, Hamideh Rezvani Alanagh, Ayeesha Mujeeb, Khosro Khajeh, Guangjun Nie
Dopamine Delivery via pH-Sensitive Nanoparticles for Tumor Blood Vessel Normalization and an Improved Effect of Cancer Chemotherapeutic Drugs. Advanced healthcare materials 8 (18) (2019)
Lijing Zhang, Yingqiu Qi, Huan Min, Chen Ni, Fei Wang, Bin Wang, Hao Qin, Yinlong Zhang, Guangna Liu, Yue Qin, Xixi Duan, Feng Li, Xuexiang Han, Ning Tao, Lirong Zhang, Zhihai Qin, Ying Zhao, Guangjun Nie
Cooperatively Responsive Peptide Nanotherapeutic that Regulates Angiopoietin Receptor Tie2 Activity in Tumor Microenvironment To Prevent Breast Tumor Relapse after Chemotherapy. ACS nano 13 (5) (2019)
Huan Min, Yingqiu Qi, Yanhuan Chen, Yinlong Zhang, Xuexiang Han, Ying Xu, Ying Liu, Jianshe Hu, Huibiao Liu, Yiye Li, Guangjun Nie
Synthesis and Imaging of Biocompatible Graphdiyne Quantum Dots. ACS applied materials & interfaces 11 (36) (2019)
Jiayan Lang, Xiao Zhao, Yingqiu Qi, Yinlong Zhang, Xuexiang Han, Yanping Ding, Jiajing Guan, Tianjiao Ji, Ying Zhao, Guangjun Nie
Reshaping Prostate Tumor Microenvironment To Suppress Metastasis via Cancer-Associated Fibroblast Inactivation with Peptide-Assembly-Based Nanosystem. ACS nano 13 (11) (2019)
Xuexiang Han, Ying Xu, Yiye Li, Xiao Zhao, Yinlong Zhang, Huan Min, Yingqiu Qi, Gregory J Anderson, Linhao You, Yuliang Zhao, Guangjun Nie
An Extendable Star-Like Nanoplatform for Functional and Anatomical Imaging-Guided Photothermal Oncotherapy. ACS nano 13 (4) (2019)
Ying Xu, Xuexiang Han, Yiye Li, Huan Min, Xiao Zhao, Yinlong Zhang, Yingqiu Qi, Jian Shi, Sheng Qi, Yongping Bao, Guangjun Nie
Sulforaphane Mediates Glutathione Depletion via Polymeric Nanoparticles to Restore Cisplatin Chemosensitivity. ACS nano 13 (11) (2019)
Chong Du, Yingqiu Qi, Yinlong Zhang, Yazhou Wang, Xiao Zhao, Huan Min, Xuexiang Han, Jiayan Lang, Hao Qin, Quanwei Shi, Zhengkui Zhang, Xiaodong Tian, Greg J Anderson, Ying Zhao, Guangjun Nie, Yinmo Yang
Epidermal Growth Factor Receptor-Targeting Peptide Nanoparticles Simultaneously Deliver Gemcitabine and Olaparib To Treat Pancreatic Cancer with Breast Cancer 2 ( BRCA2) Mutation. ACS nano 12 (11) (2018)
Linhao You, Jing Wang, Tianqing Liu, Yinlong Zhang, Xuexiang Han, Ting Wang, Shanshan Guo, Tianyu Dong, Junchao Xu, Gregory J Anderson, Qiang Liu, Yan-Zhong Chang, Xin Lou, Guangjun Nie
Targeted Brain Delivery of Rabies Virus Glycoprotein 29-Modified Deferoxamine-Loaded Nanoparticles Reverses Functional Deficits in Parkinsonian Mice. ACS nano 12 (5) (2018)
Yingqiu Qi, Huan Min, Ayeesha Mujeeb, Yinlong Zhang, Xuexiang Han, Xiao Zhao, Greg J Anderson, Ying Zhao, Guangjun Nie
Injectable Hexapeptide Hydrogel for Localized Chemotherapy Prevents Breast Cancer Recurrence. ACS applied materials & interfaces 10 (8) (2018)