Rakan El-Mayta

Publication Activity (10 Years)

Years Active: 2023-2024
Publications (10 Years): 26

Top Topics

Multiple Myeloma

Top Venues

Nature communications

Nature biomedical engineering

Science advances

Proceedings of the National Academy of Sciences of the United States of America

This page only lists publications with an associated author ORCID identifier.

Publications

Ningqiang Gong, Mohamad-Gabriel Alameh, Rakan El-Mayta, Lulu Xue, Drew Weissman, Michael J Mitchell
Enhancing in situ cancer vaccines using delivery technologies. Nature reviews. Drug discovery 23 (8) (2024)
Xuexiang Han, Mohamad-Gabriel Alameh, Ningqiang Gong, Lulu Xue, Majed Ghattas, Goutham Bojja, Junchao Xu, Gan Zhao, Claude C Warzecha, Marshall S Padilla, Rakan El-Mayta, Garima Dwivedi, Ying Xu, Andrew E Vaughan, James M Wilson, Drew Weissman, Michael J Mitchell
Fast and facile synthesis of amidine-incorporated degradable lipids for versatile mRNA delivery in vivo. Nature chemistry (2024)
Lulu Xue, Alex G Hamilton, Gan Zhao, Zebin Xiao, Rakan El-Mayta, Xuexiang Han, Ningqiang Gong, Xinhong Xiong, Junchao Xu, Christian G Figueroa-Espada, Sarah J Shepherd, Alvin J Mukalel, Mohamad Gabriel Alameh, Jiaxi Cui, Karin Wang, Andrew E Vaughan, Drew Weissman, Michael J Mitchell
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models. Nature communications 15 (1) (2024)
Lulu Xue, Alex G Hamilton, Gan Zhao, Zebin Xiao, Rakan El-Mayta, Xuexiang Han, Ningqiang Gong, Xinhong Xiong, Junchao Xu, Christian G Figueroa-Espada, Sarah J Shepherd, Alvin J Mukalel, Mohamad Gabriel Alameh, Jiaxi Cui, Karin Wang, Andrew E Vaughan, Drew Weissman, Michael J Mitchell
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models. Nature communications 15 (1) (2024)
Ningqiang Gong, Wenqun Zhong, Mohamad Gabriel Alameh, Xuexiang Han, Lulu Xue, Rakan El-Mayta, Gan Zhao, Andrew E Vaughan, Zhiyuan Qin, Fengyuan Xu, Alex G Hamilton, Dongyoon Kim, Junchao Xu, Junhyong Kim, Xucong Teng, Jinghong Li, Xing-Jie Liang, Drew Weissman, Wei Guo, Michael J Mitchell
Tumour-derived small extracellular vesicles act as a barrier to therapeutic nanoparticle delivery. Nature materials (2024)
Ningqiang Gong, Xuexiang Han, Lulu Xue, Margaret M Billingsley, Xisha Huang, Rakan El-Mayta, Jingya Qin, Neil C Sheppard, Carl H June, Michael J Mitchell
Small-molecule-mediated control of the anti-tumour activity and off-tumour toxicity of a supramolecular bispecific T cell engager. Nature biomedical engineering 8 (5) (2024)
Lulu Xue, Alex G Hamilton, Gan Zhao, Zebin Xiao, Rakan El-Mayta, Xuexiang Han, Ningqiang Gong, Xinhong Xiong, Junchao Xu, Christian G Figueroa-Espada, Sarah J Shepherd, Alvin J Mukalel, Mohamad Gabriel Alameh, Jiaxi Cui, Karin Wang, Andrew E Vaughan, Drew Weissman, Michael J Mitchell
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models. Nature communications 15 (1) (2024)
Ningqiang Gong, Xuexiang Han, Lulu Xue, Margaret M Billingsley, Xisha Huang, Rakan El-Mayta, Jingya Qin, Neil C Sheppard, Carl H June, Michael J Mitchell
Small-molecule-mediated control of the anti-tumour activity and off-tumour toxicity of a supramolecular bispecific T cell engager. Nature biomedical engineering (2024)
Fan Yang, Md Naushad Akhtar, Duo Zhang, Rakan El-Mayta, Junyoung Shin, Jay F Dorsey, Lin Zhang, George X Xu, Wei Guo, Stephen J Bagley, Serge Y Fuchs, Constantinos Koumenis, Justin D Lathia, Michael J Mitchell, Yanqing Gong, Yi Fan
An immunosuppressive vascular niche drives macrophage polarization and immunotherapy resistance in glioblastoma. Science advances 10 (9) (2024)
Ningqiang Gong, Mohamad-Gabriel Alameh, Rakan El-Mayta, Lulu Xue, Drew Weissman, Michael J Mitchell
Enhancing in situ cancer vaccines using delivery technologies. Nature reviews. Drug discovery (2024)
Ningqiang Gong, Xuexiang Han, Lulu Xue, Margaret M Billingsley, Xisha Huang, Rakan El-Mayta, Jingya Qin, Neil C Sheppard, Carl H June, Michael J Mitchell
Small-molecule-mediated control of the anti-tumour activity and off-tumour toxicity of a supramolecular bispecific T cell engager. Nature biomedical engineering (2024)
Fan Yang, Md Naushad Akhtar, Duo Zhang, Rakan El-Mayta, Junyoung Shin, Jay F Dorsey, Lin Zhang, George X Xu, Wei Guo, Stephen J Bagley, Serge Y Fuchs, Constantinos Koumenis, Justin D Lathia, Michael J Mitchell, Yanqing Gong, Yi Fan
An immunosuppressive vascular niche drives macrophage polarization and immunotherapy resistance in glioblastoma. Science advances 10 (9) (2024)
Xuexiang Han, Junchao Xu, Ying Xu, Mohamad Gabriel Alameh, Lulu Xue, Ningqiang Gong, Rakan El-Mayta, Rohan Palanki, Claude C Warzecha, Gan Zhao, Andrew E Vaughan, James M Wilson, Drew Weissman, Michael J Mitchell
In situ combinatorial synthesis of degradable branched lipidoids for systemic delivery of mRNA therapeutics and gene editors. Nature communications 15 (1) (2024)
Lulu Xue, Alex G Hamilton, Gan Zhao, Zebin Xiao, Rakan El-Mayta, Xuexiang Han, Ningqiang Gong, Xinhong Xiong, Junchao Xu, Christian G Figueroa-Espada, Sarah J Shepherd, Alvin J Mukalel, Mohamad Gabriel Alameh, Jiaxi Cui, Karin Wang, Andrew E Vaughan, Drew Weissman, Michael J Mitchell
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models. Nature communications 15 (1) (2024)
Fan Yang, Md Naushad Akhtar, Duo Zhang, Rakan El-Mayta, Junyoung Shin, Jay F Dorsey, Lin Zhang, George X Xu, Wei Guo, Stephen J Bagley, Serge Y Fuchs, Constantinos Koumenis, Justin D Lathia, Michael J Mitchell, Yanqing Gong, Yi Fan
An immunosuppressive vascular niche drives macrophage polarization and immunotherapy resistance in glioblastoma. Science advances 10 (9) (2024)
Lulu Xue, Alex G Hamilton, Gan Zhao, Zebin Xiao, Rakan El-Mayta, Xuexiang Han, Ningqiang Gong, Xinhong Xiong, Junchao Xu, Christian G Figueroa-Espada, Sarah J Shepherd, Alvin J Mukalel, Mohamad Gabriel Alameh, Jiaxi Cui, Karin Wang, Andrew E Vaughan, Drew Weissman, Michael J Mitchell
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models. Nature communications 15 (1) (2024)
Ningqiang Gong, Xuexiang Han, Lulu Xue, Margaret M Billingsley, Xisha Huang, Rakan El-Mayta, Jingya Qin, Neil C Sheppard, Carl H June, Michael J Mitchell
Small-molecule-mediated control of the anti-tumour activity and off-tumour toxicity of a supramolecular bispecific T cell engager. Nature biomedical engineering 8 (5) (2024)
Ningqiang Gong, Xuexiang Han, Lulu Xue, Margaret M Billingsley, Xisha Huang, Rakan El-Mayta, Jingya Qin, Neil C Sheppard, Carl H June, Michael J Mitchell
Author Correction: Small-molecule-mediated control of the anti-tumour activity and off-tumour toxicity of a supramolecular bispecific T cell engager. Nature biomedical engineering (2024)
Lulu Xue, Alex G Hamilton, Gan Zhao, Zebin Xiao, Rakan El-Mayta, Xuexiang Han, Ningqiang Gong, Xinhong Xiong, Junchao Xu, Christian G Figueroa-Espada, Sarah J Shepherd, Alvin J Mukalel, Mohamad Gabriel Alameh, Jiaxi Cui, Karin Wang, Andrew E Vaughan, Drew Weissman, Michael J Mitchell
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models. Nature communications 15 (1) (2024)
Lulu Xue, Alex G Hamilton, Gan Zhao, Zebin Xiao, Rakan El-Mayta, Xuexiang Han, Ningqiang Gong, Xinhong Xiong, Junchao Xu, Christian G Figueroa-Espada, Sarah J Shepherd, Alvin J Mukalel, Mohamad Gabriel Alameh, Jiaxi Cui, Karin Wang, Andrew E Vaughan, Drew Weissman, Michael J Mitchell
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models. Nature communications 15 (1) (2024)
Xuexiang Han, Junchao Xu, Ying Xu, Mohamad Gabriel Alameh, Lulu Xue, Ningqiang Gong, Rakan El-Mayta, Rohan Palanki, Claude C Warzecha, Gan Zhao, Andrew E Vaughan, James M Wilson, Drew Weissman, Michael J Mitchell
In situ combinatorial synthesis of degradable branched lipidoids for systemic delivery of mRNA therapeutics and gene editors. Nature communications 15 (1) (2024)
Xuexiang Han, Junchao Xu, Ying Xu, Mohamad Gabriel Alameh, Lulu Xue, Ningqiang Gong, Rakan El-Mayta, Rohan Palanki, Claude C Warzecha, Gan Zhao, Andrew E Vaughan, James M Wilson, Drew Weissman, Michael J Mitchell
In situ combinatorial synthesis of degradable branched lipidoids for systemic delivery of mRNA therapeutics and gene editors. Nature communications 15 (1) (2024)
Ningqiang Gong, Xuexiang Han, Lulu Xue, Margaret M Billingsley, Xisha Huang, Rakan El-Mayta, Jingya Qin, Neil C Sheppard, Carl H June, Michael J Mitchell
Small-molecule-mediated control of the anti-tumour activity and off-tumour toxicity of a supramolecular bispecific T cell engager. Nature biomedical engineering (2024)
Pedro Pires Goulart Guimaraes, Christian G Figueroa-Espada, Rachel S Riley, Ningqiang Gong, Lulu Xue, Tomasz Sewastianik, Peter S Dennis, Claudia Loebel, Amanda Chung, Sarah J Shepherd, Rebecca M Haley, Alex G Hamilton, Rakan El-Mayta, Karin Wang, Robert S Langer, Daniel G Anderson, Ruben D Carrasco, Michael J Mitchell
In vivo bone marrow microenvironment siRNA delivery using lipid-polymer nanoparticles for multiple myeloma therapy. Proceedings of the National Academy of Sciences of the United States of America 120 (25) (2023)
Ningqiang Gong, Xuexiang Han, Lulu Xue, Rakan El-Mayta, Ann E Metzloff, Margaret M Billingsley, Alex G Hamilton, Michael J Mitchell
In situ PEGylation of CAR T cells alleviates cytokine release syndrome and neurotoxicity. Nature materials (2023)
Sarah J Shepherd, Xuexiang Han, Alvin J Mukalel, Rakan El-Mayta, Ajay S Thatte, Jingyu Wu, Marshall S Padilla, Mohamad-Gabriel Alameh, Neha Srikumar, Daeyeon Lee, Drew Weissman, David Issadore, Michael J Mitchell
Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines. Proceedings of the National Academy of Sciences of the United States of America 120 (33) (2023)