Alan Brown

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 34

Top Venues

Nature

Science (New York, N.Y.)

Nature structural & molecular biology

eLife

Harvard Medical School

University of Cambridge (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Harvard Medical School Sep 01 2017

United States

Assistant Professor :: BCMP

MRC Laboratory of Molecular Biology - Aug 31 2017

United Kingdom

Senior Investigator Scientist

MRC Laboratory of Molecular Biology

United Kingdom

Career Development Fellow

University of Cambridge

United Kingdom

Research Associate :: Department of Biochemistry

Education History

University of Cambridge

United Kingdom

PHD :: Department of Biochemistry

Publications

Daniel O Dodd, Sabrina Mechaussier, Patricia L Yeyati, Fraser McPhie, Jacob R Anderson, Chen Jing Khoo, Amelia Shoemark, Deepesh Kumar Gupta, Thomas Attard, Maimoona A Zariwala, Marie Legendre, Diana Bracht, Julia Wallmeier, Miao Gui, Mahmoud R Fassad, David A Parry, Peter A Tennant, Alison M Meynert, Gabrielle Wheway, Lucas Fares-Taie, Holly A Black, Rana Mitri-Frangieh, Catherine Faucon, Josseline Kaplan, Mitali P Patel, Lisa McKie, Roly Megaw, Christos Gatsogiannis, Mai A Mohamed, Stuart Aitken, Philippe Gautier, Finn R Reinholt, Robert A Hirst, Chris O'Callaghan, Ketil Heimdal, Mathieu Bottier, Estelle Escudier, Suzanne Crowley, Maria Descartes, Ethylin Wang Jabs, Priti Kenia, Jeanne Amiel, Giacomo Maria Bacci, Claudia Calogero, Viviana Palazzo, Lucia Tiberi, Ulrike Blümlein, Andrew Rogers, Jennifer A Wambach, Daniel J Wegner, Anne B Fulton, Margaret A Kenna, Margaret Rosenfeld, Ingrid A Holm, Alan Quigley, Emma A Hall, Laura C Murphy, Diane M Cassidy, Alexander von Kriegsheim, null null, null null, null null, Jean-François Papon, Laurent Pasquier, Marlène S Murris, James D Chalmers, Claire Hogg, Kenneth A MacLeod, Donald S Urquhart, Stefan A Unger, Timothy J Aitman, Serge Amselem, Margaret W Leigh, Michael R Knowles, Heymut Omran, Hannah M Mitchison, Alan Brown, Joseph A Marsh, Julie P I Welburn, Shih-Chieh Ti, Amjad Horani, Jean-Michel Rozet, Isabelle Perrault, Pleasantine Mill
Ciliopathy patient variants reveal organelle-specific functions for TUBB4B in axonemal microtubules. Science (New York, N.Y.) 384 (6694) (2024)
Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, Sjors H W Scheres
Automated model building and protein identification in cryo-EM maps. Nature (2024)
Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, Sjors H W Scheres
Automated model building and protein identification in cryo-EM maps. Nature 628 (8007) (2024)
Daniel O Dodd, Sabrina Mechaussier, Patricia L Yeyati, Fraser McPhie, Jacob R Anderson, Chen Jing Khoo, Amelia Shoemark, Deepesh Kumar Gupta, Thomas Attard, Maimoona A Zariwala, Marie Legendre, Diana Bracht, Julia Wallmeier, Miao Gui, Mahmoud R Fassad, David A Parry, Peter A Tennant, Alison M Meynert, Gabrielle Wheway, Lucas Fares-Taie, Holly A Black, Rana Mitri-Frangieh, Catherine Faucon, Josseline Kaplan, Mitali P Patel, Lisa McKie, Roly Megaw, Christos Gatsogiannis, Mai A Mohamed, Stuart Aitken, Philippe Gautier, Finn R Reinholt, Robert A Hirst, Chris O'Callaghan, Ketil Heimdal, Mathieu Bottier, Estelle Escudier, Suzanne Crowley, Maria Descartes, Ethylin Wang Jabs, Priti Kenia, Jeanne Amiel, Giacomo Maria Bacci, Claudia Calogero, Viviana Palazzo, Lucia Tiberi, Ulrike Blümlein, Andrew Rogers, Jennifer A Wambach, Daniel J Wegner, Anne B Fulton, Margaret A Kenna, Margaret Rosenfeld, Ingrid A Holm, Alan Quigley, Emma A Hall, Laura C Murphy, Diane M Cassidy, Alexander von Kriegsheim, null null, null null, null null, Jean-François Papon, Laurent Pasquier, Marlène S Murris, James D Chalmers, Claire Hogg, Kenneth A MacLeod, Donald S Urquhart, Stefan A Unger, Timothy J Aitman, Serge Amselem, Margaret W Leigh, Michael R Knowles, Heymut Omran, Hannah M Mitchison, Alan Brown, Joseph A Marsh, Julie P I Welburn, Shih-Chieh Ti, Amjad Horani, Jean-Michel Rozet, Isabelle Perrault, Pleasantine Mill
Ciliopathy patient variants reveal organelle-specific functions for TUBB4B in axonemal microtubules. Science (New York, N.Y.) 384 (6694) (2024)
Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, Sjors H W Scheres
Automated model building and protein identification in cryo-EM maps. Nature (2024)
Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, Sjors H W Scheres
Automated model building and protein identification in cryo-EM maps. Nature (2024)
Daniel O Dodd, Sabrina Mechaussier, Patricia L Yeyati, Fraser McPhie, Jacob R Anderson, Chen Jing Khoo, Amelia Shoemark, Deepesh Kumar Gupta, Thomas Attard, Maimoona A Zariwala, Marie Legendre, Diana Bracht, Julia Wallmeier, Miao Gui, Mahmoud R Fassad, David A Parry, Peter A Tennant, Alison M Meynert, Gabrielle Wheway, Lucas Fares-Taie, Holly A Black, Rana Mitri-Frangieh, Catherine Faucon, Josseline Kaplan, Mitali P Patel, Lisa McKie, Roly Megaw, Christos Gatsogiannis, Mai A Mohamed, Stuart Aitken, Philippe Gautier, Finn R Reinholt, Robert A Hirst, Chris O'Callaghan, Ketil Heimdal, Mathieu Bottier, Estelle Escudier, Suzanne Crowley, Maria Descartes, Ethylin Wang Jabs, Priti Kenia, Jeanne Amiel, Giacomo Maria Bacci, Claudia Calogero, Viviana Palazzo, Lucia Tiberi, Ulrike Blümlein, Andrew Rogers, Jennifer A Wambach, Daniel J Wegner, Anne B Fulton, Margaret A Kenna, Margaret Rosenfeld, Ingrid A Holm, Alan Quigley, Emma A Hall, Laura C Murphy, Diane M Cassidy, Alexander von Kriegsheim, null null, null null, null null, Jean-François Papon, Laurent Pasquier, Marlène S Murris, James D Chalmers, Claire Hogg, Kenneth A MacLeod, Donald S Urquhart, Stefan A Unger, Timothy J Aitman, Serge Amselem, Margaret W Leigh, Michael R Knowles, Heymut Omran, Hannah M Mitchison, Alan Brown, Joseph A Marsh, Julie P I Welburn, Shih-Chieh Ti, Amjad Horani, Jean-Michel Rozet, Isabelle Perrault, Pleasantine Mill
Ciliopathy patient variants reveal organelle-specific functions for TUBB4B in axonemal microtubules. Science (New York, N.Y.) 384 (6694) (2024)
Daniel O Dodd, Sabrina Mechaussier, Patricia L Yeyati, Fraser McPhie, Jacob R Anderson, Chen Jing Khoo, Amelia Shoemark, Deepesh Kumar Gupta, Thomas Attard, Maimoona A Zariwala, Marie Legendre, Diana Bracht, Julia Wallmeier, Miao Gui, Mahmoud R Fassad, David A Parry, Peter A Tennant, Alison M Meynert, Gabrielle Wheway, Lucas Fares-Taie, Holly A Black, Rana Mitri-Frangieh, Catherine Faucon, Josseline Kaplan, Mitali P Patel, Lisa McKie, Roly Megaw, Christos Gatsogiannis, Mai A Mohamed, Stuart Aitken, Philippe Gautier, Finn R Reinholt, Robert A Hirst, Chris O'Callaghan, Ketil Heimdal, Mathieu Bottier, Estelle Escudier, Suzanne Crowley, Maria Descartes, Ethylin Wang Jabs, Priti Kenia, Jeanne Amiel, Giacomo Maria Bacci, Claudia Calogero, Viviana Palazzo, Lucia Tiberi, Ulrike Blümlein, Andrew Rogers, Jennifer A Wambach, Daniel J Wegner, Anne B Fulton, Margaret A Kenna, Margaret Rosenfeld, Ingrid A Holm, Alan Quigley, Emma A Hall, Laura C Murphy, Diane M Cassidy, Alexander von Kriegsheim, null null, null null, null null, Jean-François Papon, Laurent Pasquier, Marlène S Murris, James D Chalmers, Claire Hogg, Kenneth A MacLeod, Donald S Urquhart, Stefan A Unger, Timothy J Aitman, Serge Amselem, Margaret W Leigh, Michael R Knowles, Heymut Omran, Hannah M Mitchison, Alan Brown, Joseph A Marsh, Julie P I Welburn, Shih-Chieh Ti, Amjad Horani, Jean-Michel Rozet, Isabelle Perrault, Pleasantine Mill
Ciliopathy patient variants reveal organelle-specific functions for TUBB4B in axonemal microtubules. Science (New York, N.Y.) 384 (6694) (2024)
Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, Sjors H W Scheres
Automated model building and protein identification in cryo-EM maps. Nature (2024)
Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, Sjors H W Scheres
Automated model building and protein identification in cryo-EM maps. Nature 628 (8007) (2024)
Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, Sjors H W Scheres
Automated model building and protein identification in cryo-EM maps. Nature 628 (8007) (2024)
Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, Sjors H W Scheres
Automated model building and protein identification in cryo-EM maps. Nature (2024)
Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, Sjors H W Scheres
Automated model building and protein identification in cryo-EM maps. Nature 628 (8007) (2024)
Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, Sjors H W Scheres
Automated model building and protein identification in cryo-EM maps. Nature 628 (8007) (2024)
Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, Sjors H W Scheres
Automated model building and protein identification in cryo-EM maps. Nature (2024)
Daniel O Dodd, Sabrina Mechaussier, Patricia L Yeyati, Fraser McPhie, Jacob R Anderson, Chen Jing Khoo, Amelia Shoemark, Deepesh Kumar Gupta, Thomas Attard, Maimoona A Zariwala, Marie Legendre, Diana Bracht, Julia Wallmeier, Miao Gui, Mahmoud R Fassad, David A Parry, Peter A Tennant, Alison M Meynert, Gabrielle Wheway, Lucas Fares-Taie, Holly A Black, Rana Mitri-Frangieh, Catherine Faucon, Josseline Kaplan, Mitali P Patel, Lisa McKie, Roly Megaw, Christos Gatsogiannis, Mai A Mohamed, Stuart Aitken, Philippe Gautier, Finn R Reinholt, Robert A Hirst, Chris O'Callaghan, Ketil Heimdal, Mathieu Bottier, Estelle Escudier, Suzanne Crowley, Maria Descartes, Ethylin Wang Jabs, Priti Kenia, Jeanne Amiel, Giacomo Maria Bacci, Claudia Calogero, Viviana Palazzo, Lucia Tiberi, Ulrike Blümlein, Andrew Rogers, Jennifer A Wambach, Daniel J Wegner, Anne B Fulton, Margaret A Kenna, Margaret Rosenfeld, Ingrid A Holm, Alan Quigley, Emma A Hall, Laura C Murphy, Diane M Cassidy, Alexander von Kriegsheim, null null, null null, null null, Jean-François Papon, Laurent Pasquier, Marlène S Murris, James D Chalmers, Claire Hogg, Kenneth A MacLeod, Donald S Urquhart, Stefan A Unger, Timothy J Aitman, Serge Amselem, Margaret W Leigh, Michael R Knowles, Heymut Omran, Hannah M Mitchison, Alan Brown, Joseph A Marsh, Julie P I Welburn, Shih-Chieh Ti, Amjad Horani, Jean-Michel Rozet, Isabelle Perrault, Pleasantine Mill
Ciliopathy patient variants reveal organelle-specific functions for TUBB4B in axonemal microtubules. Science (New York, N.Y.) 384 (6694) (2024)
Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, Sjors H W Scheres
Automated model building and protein identification in cryo-EM maps. Nature (2024)
Daniel O Dodd, Sabrina Mechaussier, Patricia L Yeyati, Fraser McPhie, Jacob R Anderson, Chen Jing Khoo, Amelia Shoemark, Deepesh Kumar Gupta, Thomas Attard, Maimoona A Zariwala, Marie Legendre, Diana Bracht, Julia Wallmeier, Miao Gui, Mahmoud R Fassad, David A Parry, Peter A Tennant, Alison M Meynert, Gabrielle Wheway, Lucas Fares-Taie, Holly A Black, Rana Mitri-Frangieh, Catherine Faucon, Josseline Kaplan, Mitali P Patel, Lisa McKie, Roly Megaw, Christos Gatsogiannis, Mai A Mohamed, Stuart Aitken, Philippe Gautier, Finn R Reinholt, Robert A Hirst, Chris O'Callaghan, Ketil Heimdal, Mathieu Bottier, Estelle Escudier, Suzanne Crowley, Maria Descartes, Ethylin Wang Jabs, Priti Kenia, Jeanne Amiel, Giacomo Maria Bacci, Claudia Calogero, Viviana Palazzo, Lucia Tiberi, Ulrike Blümlein, Andrew Rogers, Jennifer A Wambach, Daniel J Wegner, Anne B Fulton, Margaret A Kenna, Margaret Rosenfeld, Ingrid A Holm, Alan Quigley, Emma A Hall, Laura C Murphy, Diane M Cassidy, Alexander von Kriegsheim, null null, null null, null null, Jean-François Papon, Laurent Pasquier, Marlène S Murris, James D Chalmers, Claire Hogg, Kenneth A MacLeod, Donald S Urquhart, Stefan A Unger, Timothy J Aitman, Serge Amselem, Margaret W Leigh, Michael R Knowles, Heymut Omran, Hannah M Mitchison, Alan Brown, Joseph A Marsh, Julie P I Welburn, Shih-Chieh Ti, Amjad Horani, Jean-Michel Rozet, Isabelle Perrault, Pleasantine Mill
Ciliopathy patient variants reveal organelle-specific functions for TUBB4B in axonemal microtubules. Science (New York, N.Y.) 384 (6694) (2024)
Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, Sjors H W Scheres
Automated model building and protein identification in cryo-EM maps. Nature 628 (8007) (2024)
Travis Walton, Miao Gui, Simona Velkova, Mahmoud R Fassad, Robert A Hirst, Eric Haarman, Christopher O'Callaghan, Mathieu Bottier, Thomas Burgoyne, Hannah M Mitchison, Alan Brown
Axonemal structures reveal mechanoregulatory and disease mechanisms. Nature (2023)
Miao Gui, Jacob T Croft, Davide Zabeo, Vajradhar Acharya, Justin M Kollman, Thomas Burgoyne, Johanna L Höög, Alan Brown
SPACA9 is a lumenal protein of human ciliary singlet and doublet microtubules. Proceedings of the National Academy of Sciences of the United States of America 119 (41) (2022)
Manuel F Juette, Jordan D Carelli, Emily J Rundlet, Alan Brown, Sichen Shao, Angelica Ferguson, Michael R Wasserman, Mikael Holm, Jack Taunton, Scott C Blanchard
Didemnin B and ternatin-4 differentially inhibit conformational changes in eEF1A required for aminoacyl-tRNA accommodation into mammalian ribosomes. eLife 11 (2022)
Jacob R Anderson, Jing Li, Timothy A Springer, Alan Brown
Structures of VWF tubules before and after concatemerization reveal a mechanism of disulfide bond exchange. Blood 140 (12) (2022)
Miao Gui, Xiangli Wang, Susan K Dutcher, Alan Brown, Rui Zhang
Ciliary central apparatus structure reveals mechanisms of microtubule patterning. Nature structural & molecular biology 29 (5) (2022)
Xiangli Wang, Yong Fu, Wandy L Beatty, Meisheng Ma, Alan Brown, L David Sibley, Rui Zhang
Cryo-EM structure of cortical microtubules from human parasite Toxoplasma gondii identifies their microtubule inner proteins. Nature communications 12 (1) (2021)
Meng Zhang, Miao Gui, Zi-Fu Wang, Christoph Gorgulla, James J Yu, Hao Wu, Zhen-Yu J Sun, Christoph Klenk, Lisa Merklinger, Lena Morstein, Franz Hagn, Andreas Plückthun, Alan Brown, Mahmoud L Nasr, Gerhard Wagner
Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs. Nature structural & molecular biology 28 (3) (2021)
Travis Walton, Hao Wu, Alan Brown
Structure of a microtubule-bound axonemal dynein. Nature communications 12 (1) (2021)
Haixia Zhou, Manal S Zaher, Johannes C Walter, Alan Brown
Structure of CRL2Lrr1, the E3 ubiquitin ligase that promotes DNA replication termination in vertebrates. Nucleic acids research (2021)
Xiangli Wang, Yong Fu, Wandy L Beatty, Meisheng Ma, Alan Brown, L David Sibley, Rui Zhang
Publisher Correction: Cryo-EM structure of cortical microtubules from human parasite Toxoplasma gondii identifies their microtubule inner proteins. Nature communications 12 (1) (2021)
Sandeep K Singh, Miao Gui, Fujiet Koh, Matthew C J Yip, Alan Brown
Structure and activation mechanism of the BBSome membrane protein trafficking complex. eLife 9 (2020)
Miao Gui, Meisheng Ma, Erica Sze-Tu, Xiangli Wang, Fujiet Koh, Ellen D Zhong, Bonnie Berger, Joseph H Davis, Susan K Dutcher, Rui Zhang, Alan Brown
Structures of radial spokes and associated complexes important for ciliary motility. Nature structural & molecular biology 28 (1) (2020)
Viswanathan Chandrasekaran, Szymon Juszkiewicz, Junhong Choi, Joseph D Puglisi, Alan Brown, Sichen Shao, V Ramakrishnan, Ramanujan S Hegde
Mechanism of ribosome stalling during translation of a poly(A) tail. Nature structural & molecular biology 26 (12) (2019)
Alan Brown, Matthew R Baird, Matthew C J Yip, Jason Murray, Sichen Shao
Structures of translationally inactive mammalian ribosomes. eLife 7 (2018)
Alan Brown, Sorbhi Rathore, Dari Kimanius, Shintaro Aibara, Xiao-Chen Bai, Joanna Rorbach, Alexey Amunts, V Ramakrishnan
Structures of the human mitochondrial ribosome in native states of assembly. Nature structural & molecular biology 24 (10) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Alan Brown