Michal Minczuk

ResearcherID Loop profile Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 36

Top Topics

Hypertrophic Cardiomyopathy

Duchenne Muscular Dystrophy

Quality Control

Top Venues

Nature communications

Journal of inherited metabolic disease

This page only lists publications with an associated author ORCID identifier.

Publications

Christian D Mutti, Lindsey Van Haute, Michal Minczuk
The catalytic activity of methyltransferase METTL15 is dispensable for its role in mitochondrial ribosome biogenesis. RNA biology 21 (1) (2024)
Nandaki Keshavan, Michal Minczuk, Carlos Pardo-Hernández, Shamima Rahman
Gene therapy for mitochondrial disorders. Journal of inherited metabolic disease (2024)
Christian D Mutti, Lindsey Van Haute, Michal Minczuk
The catalytic activity of methyltransferase METTL15 is dispensable for its role in mitochondrial ribosome biogenesis. RNA biology 21 (1) (2024)
Nandaki Keshavan, Michal Minczuk, Carlos Pardo-Hernández, Shamima Rahman
Gene therapy for mitochondrial disorders. Journal of inherited metabolic disease 47 (1) (2024)
Miriam Cipullo, Genís Valentín Gesé, Shreekara Gopalakrishna, Annika Krueger, Vivian Lobo, Maria A Pirozhkova, James Marks, Petra Páleníková, Dmitrii Shiriaev, Yong Liu, Jelena Misic, Yu Cai, Minh Duc Nguyen, Abubakar Abdelbagi, Xinping Li, Michal Minczuk, Markus Hafner, Daniel Benhalevy, Aishe A Sarshad, Ilian Atanassov, B Martin Hällberg, Joanna Rorbach
GTPBP8 plays a role in mitoribosome formation in human mitochondria. Nature communications 15 (1) (2024)
Miriam Cipullo, Genís Valentín Gesé, Shreekara Gopalakrishna, Annika Krueger, Vivian Lobo, Maria A Pirozhkova, James Marks, Petra Páleníková, Dmitrii Shiriaev, Yong Liu, Jelena Misic, Yu Cai, Minh Duc Nguyen, Abubakar Abdelbagi, Xinping Li, Michal Minczuk, Markus Hafner, Daniel Benhalevy, Aishe A Sarshad, Ilian Atanassov, B Martin Hällberg, Joanna Rorbach
GTPBP8 plays a role in mitoribosome formation in human mitochondria. Nature communications 15 (1) (2024)
Miriam Cipullo, Genís Valentín Gesé, Shreekara Gopalakrishna, Annika Krueger, Vivian Lobo, Maria A Pirozhkova, James Marks, Petra Páleníková, Dmitrii Shiriaev, Yong Liu, Jelena Misic, Yu Cai, Minh Duc Nguyen, Abubakar Abdelbagi, Xinping Li, Michal Minczuk, Markus Hafner, Daniel Benhalevy, Aishe A Sarshad, Ilian Atanassov, B Martin Hällberg, Joanna Rorbach
GTPBP8 plays a role in mitoribosome formation in human mitochondria. Nature communications 15 (1) (2024)
Christian D Mutti, Lindsey Van Haute, Michal Minczuk
The catalytic activity of methyltransferase METTL15 is dispensable for its role in mitochondrial ribosome biogenesis. RNA biology 21 (1) (2024)
Nandaki Keshavan, Michal Minczuk, Carlos Pardo-Hernández, Shamima Rahman
Gene therapy for mitochondrial disorders. Journal of inherited metabolic disease 47 (1) (2024)
Christian D Mutti, Lindsey Van Haute, Michal Minczuk
The catalytic activity of methyltransferase METTL15 is dispensable for its role in mitochondrial ribosome biogenesis. RNA biology 21 (1) (2024)
Nandaki Keshavan, Michal Minczuk, Carlos Pardo-Hernández, Shamima Rahman
Gene therapy for mitochondrial disorders. Journal of inherited metabolic disease 47 (1) (2024)
Lindsey Van Haute, Emily O'Connor, Héctor Díaz-Maldonado, Benjamin Munro, Kiran Polavarapu, Daniella Helena Hock, Gautham Arunachal, Alkyoni Athanasiou-Fragkouli, Mainak Bardhan, Magalie Barth, Dominique Bonneau, Nicola Brunetti-Pierri, Gerarda Cappuccio, Nikeisha J Caruana, Natalia Dominik, Himanshu Goel, Guy Helman, Henry Houlden, Guy Lenaers, Karine Mention, David Murphy, Bevinahalli Nandeesh, Catarina Olimpio, Christopher A Powell, Veeramani Preethish-Kumar, Vincent Procaccio, Rocio Rius, Pedro Rebelo-Guiomar, Cas Simons, Seena Vengalil, Maha Saad Zaki, Alban Ziegler, David R Thorburn, David Arthur Stroud, Reza Maroofian, John Chrisodoulou, Claes M Gustafsson, Atchayaram Nalini, Hanns Lochmüller, Michal Minczuk, Rita Horvath
TEFM variants impair mitochondrial transcription causing childhood-onset neurological disease. Nature communications 14 (1) (2023)
Lindsey Van Haute, Emily O'Connor, Héctor Díaz-Maldonado, Benjamin Munro, Kiran Polavarapu, Daniella Helena Hock, Gautham Arunachal, Alkyoni Athanasiou-Fragkouli, Mainak Bardhan, Magalie Barth, Dominique Bonneau, Nicola Brunetti-Pierri, Gerarda Cappuccio, Nikeisha J Caruana, Natalia Dominik, Himanshu Goel, Guy Helman, Henry Houlden, Guy Lenaers, Karine Mention, David Murphy, Bevinahalli Nandeesh, Catarina Olimpio, Christopher A Powell, Veeramani Preethish-Kumar, Vincent Procaccio, Rocio Rius, Pedro Rebelo-Guiomar, Cas Simons, Seena Vengalil, Maha Saad Zaki, Alban Ziegler, David R Thorburn, David Arthur Stroud, Reza Maroofian, John Chrisodoulou, Claes M Gustafsson, Atchayaram Nalini, Hanns Lochmüller, Michal Minczuk, Rita Horvath
TEFM variants impair mitochondrial transcription causing childhood-onset neurological disease. Nature communications 14 (1) (2023)
Lindsey Van Haute, Emily O'Connor, Héctor Díaz-Maldonado, Benjamin Munro, Kiran Polavarapu, Daniella Helena Hock, Gautham Arunachal, Alkyoni Athanasiou-Fragkouli, Mainak Bardhan, Magalie Barth, Dominique Bonneau, Nicola Brunetti-Pierri, Gerarda Cappuccio, Nikeisha J Caruana, Natalia Dominik, Himanshu Goel, Guy Helman, Henry Houlden, Guy Lenaers, Karine Mention, David Murphy, Bevinahalli Nandeesh, Catarina Olimpio, Christopher A Powell, Veeramani Preethish-Kumar, Vincent Procaccio, Rocio Rius, Pedro Rebelo-Guiomar, Cas Simons, Seena Vengalil, Maha Saad Zaki, Alban Ziegler, David R Thorburn, David Arthur Stroud, Reza Maroofian, John Chrisodoulou, Claes M Gustafsson, Atchayaram Nalini, Hanns Lochmüller, Michal Minczuk, Rita Horvath
TEFM variants impair mitochondrial transcription causing childhood-onset neurological disease. Nature communications 14 (1) (2023)
Lindsey Van Haute, Emily O'Connor, Héctor Díaz-Maldonado, Benjamin Munro, Kiran Polavarapu, Daniella Helena Hock, Gautham Arunachal, Alkyoni Athanasiou-Fragkouli, Mainak Bardhan, Magalie Barth, Dominique Bonneau, Nicola Brunetti-Pierri, Gerarda Cappuccio, Nikeisha J Caruana, Natalia Dominik, Himanshu Goel, Guy Helman, Henry Houlden, Guy Lenaers, Karine Mention, David Murphy, Bevinahalli Nandeesh, Catarina Olimpio, Christopher A Powell, Veeramani Preethish-Kumar, Vincent Procaccio, Rocio Rius, Pedro Rebelo-Guiomar, Cas Simons, Seena Vengalil, Maha Saad Zaki, Alban Ziegler, David R Thorburn, David Arthur Stroud, Reza Maroofian, John Chrisodoulou, Claes M Gustafsson, Atchayaram Nalini, Hanns Lochmüller, Michal Minczuk, Rita Horvath
TEFM variants impair mitochondrial transcription causing childhood-onset neurological disease. Nature communications 14 (1) (2023)
Lindsey Van Haute, Emily O'Connor, Héctor Díaz-Maldonado, Benjamin Munro, Kiran Polavarapu, Daniella Helena Hock, Gautham Arunachal, Alkyoni Athanasiou-Fragkouli, Mainak Bardhan, Magalie Barth, Dominique Bonneau, Nicola Brunetti-Pierri, Gerarda Cappuccio, Nikeisha J Caruana, Natalia Dominik, Himanshu Goel, Guy Helman, Henry Houlden, Guy Lenaers, Karine Mention, David Murphy, Bevinahalli Nandeesh, Catarina Olimpio, Christopher A Powell, Veeramani Preethish-Kumar, Vincent Procaccio, Rocio Rius, Pedro Rebelo-Guiomar, Cas Simons, Seena Vengalil, Maha Saad Zaki, Alban Ziegler, David R Thorburn, David Arthur Stroud, Reza Maroofian, John Chrisodoulou, Claes M Gustafsson, Atchayaram Nalini, Hanns Lochmüller, Michal Minczuk, Rita Horvath
TEFM variants impair mitochondrial transcription causing childhood-onset neurological disease. Nature communications 14 (1) (2023)
Lindsey Van Haute, Emily O'Connor, Héctor Díaz-Maldonado, Benjamin Munro, Kiran Polavarapu, Daniella Helena Hock, Gautham Arunachal, Alkyoni Athanasiou-Fragkouli, Mainak Bardhan, Magalie Barth, Dominique Bonneau, Nicola Brunetti-Pierri, Gerarda Cappuccio, Nikeisha J Caruana, Natalia Dominik, Himanshu Goel, Guy Helman, Henry Houlden, Guy Lenaers, Karine Mention, David Murphy, Bevinahalli Nandeesh, Catarina Olimpio, Christopher A Powell, Veeramani Preethish-Kumar, Vincent Procaccio, Rocio Rius, Pedro Rebelo-Guiomar, Cas Simons, Seena Vengalil, Maha Saad Zaki, Alban Ziegler, David R Thorburn, David Arthur Stroud, Reza Maroofian, John Chrisodoulou, Claes M Gustafsson, Atchayaram Nalini, Hanns Lochmüller, Michal Minczuk, Rita Horvath
TEFM variants impair mitochondrial transcription causing childhood-onset neurological disease. Nature communications 14 (1) (2023)
Lindsey Van Haute, Emily O'Connor, Héctor Díaz-Maldonado, Benjamin Munro, Kiran Polavarapu, Daniella Helena Hock, Gautham Arunachal, Alkyoni Athanasiou-Fragkouli, Mainak Bardhan, Magalie Barth, Dominique Bonneau, Nicola Brunetti-Pierri, Gerarda Cappuccio, Nikeisha J Caruana, Natalia Dominik, Himanshu Goel, Guy Helman, Henry Houlden, Guy Lenaers, Karine Mention, David Murphy, Bevinahalli Nandeesh, Catarina Olimpio, Christopher A Powell, Veeramani Preethish-Kumar, Vincent Procaccio, Rocio Rius, Pedro Rebelo-Guiomar, Cas Simons, Seena Vengalil, Maha Saad Zaki, Alban Ziegler, David R Thorburn, David Arthur Stroud, Reza Maroofian, John Chrisodoulou, Claes M Gustafsson, Atchayaram Nalini, Hanns Lochmüller, Michal Minczuk, Rita Horvath
TEFM variants impair mitochondrial transcription causing childhood-onset neurological disease. Nature communications 14 (1) (2023)
Micol Falabella, Michal Minczuk, Michael G Hanna, Carlo Viscomi, Robert D S Pitceathly
Gene therapy for primary mitochondrial diseases: experimental advances and clinical challenges. Nature reviews. Neurology 18 (11) (2022)
Pedro Silva-Pinheiro, Pavel A Nash, Lindsey Van Haute, Christian D Mutti, Keira Turner, Michal Minczuk
In vivo mitochondrial base editing via adeno-associated viral delivery to mouse post-mitotic tissue. Nature communications 13 (1) (2022)
Pedro Silva-Pinheiro, Christian D Mutti, Lindsey Van Haute, Christopher A Powell, Pavel A Nash, Keira Turner, Michal Minczuk
A library of base editors for the precise ablation of all protein-coding genes in the mouse mitochondrial genome. Nature biomedical engineering (2022)
Julian C W Willis, Pedro Silva-Pinheiro, Lily Widdup, Michal Minczuk, David R Liu
Compact zinc finger base editors that edit mitochondrial or nuclear DNA in vitro and in vivo. Nature communications 13 (1) (2022)
Pedro Rebelo-Guiomar, Simone Pellegrino, Kyle C Dent, Aldema Sas-Chen, Leonor Miller-Fleming, Caterina Garone, Lindsey Van Haute, Jack F Rogan, Adam Dinan, Andrew E Firth, Byron Andrews, Alexander J Whitworth, Schraga Schwartz, Alan John Warren, Michal Minczuk
A late-stage assembly checkpoint of the human mitochondrial ribosome large subunit. Nature communications 13 (1) (2022)
Aaron R D'Souza, Lindsey Van Haute, Christopher A Powell, Christian D Mutti, Petra Páleníková, Pedro Rebelo-Guiomar, Joanna Rorbach, Michal Minczuk
YbeY is required for ribosome small subunit assembly and tRNA processing in human mitochondria. Nucleic acids research 49 (10) (2021)
Akira Ohkubo, Lindsey Van Haute, Danielle L Rudler, Maike Stentenbach, Florian A Steiner, Oliver Rackham, Michal Minczuk, Aleksandra Filipovska, Jean-Claude Martinou
The FASTK family proteins fine-tune mitochondrial RNA processing. PLoS genetics 17 (11) (2021)
Pedro Silva-Pinheiro, Michal Minczuk
The potential of mitochondrial genome engineering. Nature reviews. Genetics (2021)
Denisa Hathazi, Helen Griffin, Matthew J Jennings, Michele Giunta, Christopher A Powell, Sarah F Pearce, Benjamin Munro, Wei Wei, Veronika Boczonadi, Joanna Poulton, Angela Pyle, Claudia Calabrese, Aurora Gomez-Duran, Ulrike Schara, Robert D S Pitceathly, Michael G Hanna, Kairit Joost, Ana Cotta, Julia Filardi Paim, Monica Machado Navarro, Jennifer Duff, Andre Mattman, Kristine Chapman, Serenella Servidei, Adela Della Marina, Johanna Uusimaa, Andreas Roos, Vamsi Mootha, Michio Hirano, Mar Tulinius, Mamta Giri, Eric P Hoffmann, Hanns Lochmüller, Salvatore DiMauro, Michal Minczuk, Patrick F Chinnery, Juliane S Müller, Rita Horvath
Metabolic shift underlies recovery in reversible infantile respiratory chain deficiency. The EMBO journal 39 (23) (2020)
Matthew Baxter, Maria Voronkov, Toryn Poolman, Gina Galli, Christian Pinali, Laurence Goosey, Abigail Knight, Karolina Krakowiak, Robert Maidstone, Mudassar Iqbal, Min Zi, Sukhpal Prehar, Elizabeth J Cartwright, Julie Gibbs, Laura C Matthews, Antony D Adamson, Neil E Humphreys, Pedro Rebelo-Guiomar, Michal Minczuk, David A Bechtold, Andrew Loudon, David Ray
Cardiac mitochondrial function depends on BUD23 mediated ribosome programming. eLife 9 (2020)
Makenzie Saoura, Christopher A Powell, Robert Kopajtich, Ahmad Alahmad, Haya H Al-Balool, Buthaina Albash, Majid Alfadhel, Charlotte L Alston, Enrico Silvio Bertini, Penelope E Bonnen, Drago Bratkovic, Rosalba Carrozzo, Maria A Donati, Michela Di Nottia, Daniele Ghezzi, Amy Goldstein, Eric Haan, Rita Horvath, Joanne Hughes, Federica Invernizzi, Eleonora Lamantea, Benjamin Lucas, Kyla-Gaye Pinnock, Maria Pujantell, Shamima Rahman, Pedro Rebelo-Guiomar, Saikat Santra, Daniela Verrigni, Robert McFarland, Holger Prokisch, Robert W Taylor, Louis Levinger, Michal Minczuk
Mutations in ELAC2 associated with hypertrophic cardiomyopathy impair mitochondrial tRNA 3'-end processing. Human mutation 40 (10) (2019)
Hanne Hoitzing, Payam A Gammage, Lindsey Van Haute, Michal Minczuk, Iain G Johnston, Nick S Jones
Energetic costs of cellular and therapeutic control of stochastic mitochondrial DNA populations. PLoS computational biology 15 (6) (2019)
Simonetta Andreazza, Colby L Samstag, Alvaro Sanchez-Martinez, Erika Fernández-Vizarra, Aurora Gomez-Duran, Juliette J Lee, Roberta Tufi, Michael J Hipp, Elizabeth K Schmidt, Thomas J Nicholls, Payam A Gammage, Patrick F Chinnery, Michal Minczuk, Leo J Pallanck, Scott R Kennedy, Alexander J Whitworth
Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila. Nature communications 10 (1) (2019)
Viktoriya Peeva, Daniel Blei, Genevieve Trombly, Sarah Corsi, Maciej J Szukszto, Pedro Rebelo-Guiomar, Payam A Gammage, Alexei P Kudin, Christian Becker, Janine Altmüller, Michal Minczuk, Gábor Zsurka, Wolfram S Kunz
Linear mitochondrial DNA is rapidly degraded by components of the replication machinery. Nature communications 9 (1) (2018)
Payam A Gammage, Carlos Pardo-Hernández, Marie-Lune Simard, Ana S H Costa, Edoardo Gaude, Christopher A Powell, Lindsey Van Haute, Beverly J McCann, Pedro Rebelo-Guiomar, Raffaele Cerutti, Lei Zhang, Edward J Rebar, Massimo Zeviani, Christian Frezza, James Bruce Stewart, Michal Minczuk
Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo. Nature medicine 24 (11) (2018)
Sofia Zaganelli, Pedro Rebelo-Guiomar, Kinsey Maundrell, Agata Rozanska, Sandra Pierredon, Christopher A Powell, Alexis A Jourdain, Nicolas Hulo, Robert N Lightowlers, Zofia M A Chrzanowska-Lightowlers, Michal Minczuk, Jean-Claude Martinou
The Pseudouridine Synthase RPUSD4 Is an Essential Component of Mitochondrial RNA Granules. The Journal of biological chemistry 292 (11) (2017)
Dipali Patel, Joanna Rorbach, Kate Downes, Maciej J Szukszto, Marcin L Pekalski, Michal Minczuk
Macropinocytic entry of isolated mitochondria in epidermal growth factor-activated human osteosarcoma cells. Scientific reports 7 (1) (2017)
Sarah F Pearce, Joanna Rorbach, Lindsey Van Haute, Aaron R D'Souza, Pedro Rebelo-Guiomar, Christopher A Powell, Ian Brierley, Andrew E Firth, Michal Minczuk
Maturation of selected human mitochondrial tRNAs requires deadenylation. eLife 6 (2017)