Ralf Bernd Schittenhelm (Ralf B Schittenhelm)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 88

Top Topics

Glycemic Control

Amyotrophic Lateral Sclerosis

Plasmodium Falciparum

Top Venues

Nature communications

Organic letters

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Pok Man Leung, Rhys W Grinter, Eve Tudor-Matthew, James P Lingford, Luis Jimenez, Han-Chung Lee, Michael Milton, Iresha Hanchapola, Erwin Tanuwidjaya, Ashleigh Kropp, Hanna A Peach, Carlo R Carere, Matthew B Stott, Ralf Bernd Schittenhelm, Chris Greening
Trace gas oxidation sustains energy needs of a thermophilic archaeon at suboptimal temperatures. Nature communications 15 (1) (2024)
Liam M Koehn, Joel Ricky Steele, Ralf Bernd Schittenhelm, Bradley J Turner, Joseph A Nicolazzo
Sex-Dependent Changes to the Intestinal and Hepatic Abundance of Drug Transporters and Metabolizing Enzymes in the SOD1 G93A Mouse Model of Amyotrophic Lateral Sclerosis. Molecular pharmaceutics 21 (4) (2024)
Elizabeth G Reisman, Javier Botella, Cheng Huang, Ralf Bernd Schittenhelm, David Arthur Stroud, Cesare Granata, Owala S Chandrasiri, Georg Ramm, Viola Oorschot, Nikeisha J Caruana, David J Bishop
Fibre-specific mitochondrial protein abundance is linked to resting and post-training mitochondrial content in the muscle of men. Nature communications 15 (1) (2024)
Elizabeth G Reisman, Javier Botella, Cheng Huang, Ralf Bernd Schittenhelm, David Arthur Stroud, Cesare Granata, Owala S Chandrasiri, Georg Ramm, Viola Oorschot, Nikeisha J Caruana, David J Bishop
Fibre-specific mitochondrial protein abundance is linked to resting and post-training mitochondrial content in the muscle of men. Nature communications 15 (1) (2024)
Mee Chee Chong, Anup D Shah, Ralf Bernd Schittenhelm, Anabel Silva, Patrick F James, Sam Shi Xuan Wu, Jason Howitt
Acute exercise-induced release of innate immune proteins via small extracellular vesicles changes with aerobic fitness and age. Acta physiologica (Oxford, England) (2024)
Pok Man Leung, Rhys W Grinter, Eve Tudor-Matthew, James P Lingford, Luis Jimenez, Han-Chung Lee, Michael Milton, Iresha Hanchapola, Erwin Tanuwidjaya, Ashleigh Kropp, Hanna A Peach, Carlo R Carere, Matthew B Stott, Ralf Bernd Schittenhelm, Chris Greening
Trace gas oxidation sustains energy needs of a thermophilic archaeon at suboptimal temperatures. Nature communications 15 (1) (2024)
Maxine Treisman, Laura Coe, Yongwei Zhao, Vishnu Mini Sasi, Jemma Gullick, Mathias H Hansen, Aviva Ly, Victor Leichthammer, Caroline Hess, Daniel L Machell, Ralf Bernd Schittenhelm, Joel Hooper, Colin J Jackson, Julien Tailhades, James J De Voss, Max J Cryle
An Engineered Biarylitide Cross-Linking P450 from RiPP Biosynthesis Generates Alternative Cyclic Peptides. Organic letters (2024)
Mee Chee Chong, Anup D Shah, Ralf Bernd Schittenhelm, Anabel Silva, Patrick F James, Sam Shi Xuan Wu, Jason Howitt
Acute exercise-induced release of innate immune proteins via small extracellular vesicles changes with aerobic fitness and age. Acta physiologica (Oxford, England) 240 (3) (2024)
Keith Siew, Kevin A Nestler, Charlotte A Nelson, Viola D'Ambrosio, Chutong Zhong, Zhongwang Li, Alessandra Grillo, Elizabeth R Wan, Vaksha Patel, Eliah G Overbey, Jang-Keun Kim, Sanghee Yun, Michael B Vaughan, Chris Cheshire, Laura Cubitt, Jessica Broni-Tabi, Maneera Yousef Al-Jaber, Valery Boyko, Cem Meydan, Peter Barker, Shehbeel Arif, Fatemeh Afsari, Noah Allen, Mohammed Al-Maadheed, Selin Altinok, Nourdine Bah, Samuel Border, Amanda L Brown, Keith Burling, Margareth Cheng-Campbell, Lorianna M Colón, Lovorka Degoricija, Nichola Figg, Rebecca Finch, Jonathan Foox, Pouya Faridi, Alison French, Samrawit Gebre, Peter Gordon, Nadia Houerbi, Hossein Valipour Kahrood, Frederico C Kiffer, Aleksandra S Klosinska, Angela Kubik, Han-Chung Lee, Yinghui Li, Nicholas Lucarelli, Anthony L Marullo, Irina R Matei, Colleen M McCann, Sayat Mimar, Ahmed Naglah, Jérôme Nicod, Kevin M O'Shaughnessy, Lorraine Christine De Oliveira, Leah E Oswalt, Laura Ioana Patras, San-Huei Lai Polo, Maria Rodriguez-Lopez, Candice A Roufosse, Omid Sadeghi-Alavijeh, Rebekah Sanchez-Hodge, Anindya S Paul, Ralf Bernd Schittenhelm, Annalise Schweickart, Ryan T Scott, Terry Chin Choy Lim Kam Sian, Willian A da Silveira, Hubert Slawinski, Daniel Snell, Julio Sosa, Amanda M Saravia-Butler, Marshall Tabetah, Erwin Tanuwidjaya, Simon Walker-Samuel, Xiaoping Yang, null Yasmin, Haijian Zhang, Jasminka Godovac-Zimmermann, Pinaki Sarder, Lauren M Sanders, Sylvain V Costes, Robert A A Campbell, Fathi Karouia, Vidya Mohamed-Alis, Samuel Rodriques, Steven Lynham, Joel Ricky Steele, Sergio E Baranzini, Hossein Fazelinia, Zhongquan Dai, Akira Uruno, Dai Shiba, Masayuki Yamamoto, Eduardo A C Almeida, Elizabeth Blaber, Jonathan C Schisler, Amelia J Eisch, Masafumi Muratani, Sara R Zwart, Scott M Smith, Jonathan M Galazka, Christopher E Mason, Afshin Behesti, Stephen B Walsh
Cosmic kidney disease: an integrated pan-omic, physiological and morphological study into spaceflight-induced renal dysfunction. Nature communications 15 (1) (2024)
Matthew D Blunt, Hayden Fisher, Ralf Bernd Schittenhelm, Berenice Mbiribindi, Rebecca Fulton, Sajida Khan, Laura Espana-Serrano, Lara V Graham, Leidy Bastidas-Legarda, Daniel Burns, Sophie M S Khakoo, Salah Mansour, Jonathan W Essex, Rochelle Ayala, Jayajit Das, Anthony Wayne Purcell, Salim I Khakoo
The nuclear export protein XPO1 provides a peptide ligand for natural killer cells. Science advances 10 (34) (2024)
Keith Siew, Kevin A Nestler, Charlotte A Nelson, Viola D'Ambrosio, Chutong Zhong, Zhongwang Li, Alessandra Grillo, Elizabeth R Wan, Vaksha Patel, Eliah G Overbey, Jang-Keun Kim, Sanghee Yun, Michael B Vaughan, Chris Cheshire, Laura Cubitt, Jessica Broni-Tabi, Maneera Yousef Al-Jaber, Valery Boyko, Cem Meydan, Peter Barker, Shehbeel Arif, Fatemeh Afsari, Noah Allen, Mohammed Al-Maadheed, Selin Altinok, Nourdine Bah, Samuel Border, Amanda L Brown, Keith Burling, Margareth Cheng-Campbell, Lorianna M Colón, Lovorka Degoricija, Nichola Figg, Rebecca Finch, Jonathan Foox, Pouya Faridi, Alison French, Samrawit Gebre, Peter Gordon, Nadia Houerbi, Hossein Valipour Kahrood, Frederico C Kiffer, Aleksandra S Klosinska, Angela Kubik, Han-Chung Lee, Yinghui Li, Nicholas Lucarelli, Anthony L Marullo, Irina R Matei, Colleen M McCann, Sayat Mimar, Ahmed Naglah, Jérôme Nicod, Kevin M O'Shaughnessy, Lorraine Christine De Oliveira, Leah E Oswalt, Laura Ioana Patras, San-Huei Lai Polo, Maria Rodriguez-Lopez, Candice A Roufosse, Omid Sadeghi-Alavijeh, Rebekah Sanchez-Hodge, Anindya S Paul, Ralf Bernd Schittenhelm, Annalise Schweickart, Ryan T Scott, Terry Chin Choy Lim Kam Sian, Willian A da Silveira, Hubert Slawinski, Daniel Snell, Julio Sosa, Amanda M Saravia-Butler, Marshall Tabetah, Erwin Tanuwidjaya, Simon Walker-Samuel, Xiaoping Yang, null Yasmin, Haijian Zhang, Jasminka Godovac-Zimmermann, Pinaki Sarder, Lauren M Sanders, Sylvain V Costes, Robert A A Campbell, Fathi Karouia, Vidya Mohamed-Alis, Samuel Rodriques, Steven Lynham, Joel Ricky Steele, Sergio E Baranzini, Hossein Fazelinia, Zhongquan Dai, Akira Uruno, Dai Shiba, Masayuki Yamamoto, Eduardo A C Almeida, Elizabeth Blaber, Jonathan C Schisler, Amelia J Eisch, Masafumi Muratani, Sara R Zwart, Scott M Smith, Jonathan M Galazka, Christopher E Mason, Afshin Behesti, Stephen B Walsh
Cosmic kidney disease: an integrated pan-omic, physiological and morphological study into spaceflight-induced renal dysfunction. Nature communications 15 (1) (2024)
Matthew D Blunt, Hayden Fisher, Ralf Bernd Schittenhelm, Berenice Mbiribindi, Rebecca Fulton, Sajida Khan, Laura Espana-Serrano, Lara V Graham, Leidy Bastidas-Legarda, Daniel Burns, Sophie M S Khakoo, Salah Mansour, Jonathan W Essex, Rochelle Ayala, Jayajit Das, Anthony Wayne Purcell, Salim I Khakoo
The nuclear export protein XPO1 provides a peptide ligand for natural killer cells. Science advances 10 (34) (2024)
Liam M Koehn, Joel Ricky Steele, Ralf Bernd Schittenhelm, Bradley J Turner, Joseph A Nicolazzo
Sex-Dependent Changes to the Intestinal and Hepatic Abundance of Drug Transporters and Metabolizing Enzymes in the SOD1 G93A Mouse Model of Amyotrophic Lateral Sclerosis. Molecular pharmaceutics 21 (4) (2024)
Maxine Treisman, Laura Coe, Yongwei Zhao, Vishnu Mini Sasi, Jemma Gullick, Mathias H Hansen, Aviva Ly, Victor Leichthammer, Caroline Hess, Daniel L Machell, Ralf Bernd Schittenhelm, Joel Hooper, Colin J Jackson, Julien Tailhades, James J De Voss, Max J Cryle
An Engineered Biarylitide Cross-Linking P450 from RiPP Biosynthesis Generates Alternative Cyclic Peptides. Organic letters 26 (9) (2024)
Maxine Treisman, Laura Coe, Yongwei Zhao, Vishnu Mini Sasi, Jemma Gullick, Mathias H Hansen, Aviva Ly, Victor Leichthammer, Caroline Hess, Daniel L Machell, Ralf Bernd Schittenhelm, Joel Hooper, Colin J Jackson, Julien Tailhades, James J De Voss, Max J Cryle
An Engineered Biarylitide Cross-Linking P450 from RiPP Biosynthesis Generates Alternative Cyclic Peptides. Organic letters 26 (9) (2024)
Maxine Treisman, Laura Coe, Yongwei Zhao, Vishnu Mini Sasi, Jemma Gullick, Mathias H Hansen, Aviva Ly, Victor Leichthammer, Caroline Hess, Daniel L Machell, Ralf Bernd Schittenhelm, Joel Hooper, Colin J Jackson, Julien Tailhades, James J De Voss, Max J Cryle
An Engineered Biarylitide Cross-Linking P450 from RiPP Biosynthesis Generates Alternative Cyclic Peptides. Organic letters 26 (9) (2024)
Liam M Koehn, Joel Ricky Steele, Ralf Bernd Schittenhelm, Bradley J Turner, Joseph A Nicolazzo
Sex-Dependent Changes to the Intestinal and Hepatic Abundance of Drug Transporters and Metabolizing Enzymes in the SOD1 G93A Mouse Model of Amyotrophic Lateral Sclerosis. Molecular pharmaceutics 21 (4) (2024)
Cara A Timpani, Didier Debrincat, Stephanie Kourakis, Rebecca Boyer, Luke E Formosa, Joel Ricky Steele, Haijian Zhang, Ralf Bernd Schittenhelm, Aaron P Russell, Emma Rybalka, Angus Lindsay
Loss of endogenous estrogen alters mitochondrial metabolism and muscle clock-related protein Rbm20 in female mdx mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 38 (11) (2024)
Mee Chee Chong, Anup D Shah, Ralf Bernd Schittenhelm, Anabel Silva, Patrick F James, Sam Shi Xuan Wu, Jason Howitt
Acute exercise-induced release of innate immune proteins via small extracellular vesicles changes with aerobic fitness and age. Acta physiologica (Oxford, England) 240 (3) (2024)
Yi Hsiao, Haijian Zhang, Ginny Xiaohe Li, Yamei Deng, Fengchao Yu, Hossein Valipour Kahrood, Joel Ricky Steele, Ralf Bernd Schittenhelm, Alexey I Nesvizhskii
Analysis and visualization of quantitative proteomics data using FragPipe-Analyst. bioRxiv : the preprint server for biology (2024)
Maxine Treisman, Laura Coe, Yongwei Zhao, Vishnu Mini Sasi, Jemma Gullick, Mathias H Hansen, Aviva Ly, Victor Leichthammer, Caroline Hess, Daniel L Machell, Ralf Bernd Schittenhelm, Joel Hooper, Colin J Jackson, Julien Tailhades, James J De Voss, Max J Cryle
An Engineered Biarylitide Cross-Linking P450 from RiPP Biosynthesis Generates Alternative Cyclic Peptides. Organic letters 26 (9) (2024)
Mee Chee Chong, Anup D Shah, Ralf Bernd Schittenhelm, Anabel Silva, Patrick F James, Sam Shi Xuan Wu, Jason Howitt
Acute exercise-induced release of innate immune proteins via small extracellular vesicles changes with aerobic fitness and age. Acta physiologica (Oxford, England) 240 (3) (2024)
Keith Siew, Kevin A Nestler, Charlotte A Nelson, Viola D'Ambrosio, Chutong Zhong, Zhongwang Li, Alessandra Grillo, Elizabeth R Wan, Vaksha Patel, Eliah G Overbey, Jang-Keun Kim, Sanghee Yun, Michael B Vaughan, Chris Cheshire, Laura Cubitt, Jessica Broni-Tabi, Maneera Yousef Al-Jaber, Valery Boyko, Cem Meydan, Peter Barker, Shehbeel Arif, Fatemeh Afsari, Noah Allen, Mohammed Al-Maadheed, Selin Altinok, Nourdine Bah, Samuel Border, Amanda L Brown, Keith Burling, Margareth Cheng-Campbell, Lorianna M Colón, Lovorka Degoricija, Nichola Figg, Rebecca Finch, Jonathan Foox, Pouya Faridi, Alison French, Samrawit Gebre, Peter Gordon, Nadia Houerbi, Hossein Valipour Kahrood, Frederico C Kiffer, Aleksandra S Klosinska, Angela Kubik, Han-Chung Lee, Yinghui Li, Nicholas Lucarelli, Anthony L Marullo, Irina R Matei, Colleen M McCann, Sayat Mimar, Ahmed Naglah, Jérôme Nicod, Kevin M O'Shaughnessy, Lorraine Christine De Oliveira, Leah E Oswalt, Laura Ioana Patras, San-Huei Lai Polo, Maria Rodriguez-Lopez, Candice A Roufosse, Omid Sadeghi-Alavijeh, Rebekah Sanchez-Hodge, Anindya S Paul, Ralf Bernd Schittenhelm, Annalise Schweickart, Ryan T Scott, Terry Chin Choy Lim Kam Sian, Willian A da Silveira, Hubert Slawinski, Daniel Snell, Julio Sosa, Amanda M Saravia-Butler, Marshall Tabetah, Erwin Tanuwidjaya, Simon Walker-Samuel, Xiaoping Yang, null Yasmin, Haijian Zhang, Jasminka Godovac-Zimmermann, Pinaki Sarder, Lauren M Sanders, Sylvain V Costes, Robert A A Campbell, Fathi Karouia, Vidya Mohamed-Alis, Samuel Rodriques, Steven Lynham, Joel Ricky Steele, Sergio E Baranzini, Hossein Fazelinia, Zhongquan Dai, Akira Uruno, Dai Shiba, Masayuki Yamamoto, Eduardo A C Almeida, Elizabeth Blaber, Jonathan C Schisler, Amelia J Eisch, Masafumi Muratani, Sara R Zwart, Scott M Smith, Jonathan M Galazka, Christopher E Mason, Afshin Behesti, Stephen B Walsh
Cosmic kidney disease: an integrated pan-omic, physiological and morphological study into spaceflight-induced renal dysfunction. Nature communications 15 (1) (2024)
Pok Man Leung, Rhys W Grinter, Eve Tudor-Matthew, James P Lingford, Luis Jimenez, Han-Chung Lee, Michael Milton, Iresha Hanchapola, Erwin Tanuwidjaya, Ashleigh Kropp, Hanna A Peach, Carlo R Carere, Matthew B Stott, Ralf Bernd Schittenhelm, Chris Greening
Trace gas oxidation sustains energy needs of a thermophilic archaeon at suboptimal temperatures. Nature communications 15 (1) (2024)
Liam M Koehn, Joel Ricky Steele, Ralf Bernd Schittenhelm, Bradley J Turner, Joseph A Nicolazzo
Sex-Dependent Changes to the Intestinal and Hepatic Abundance of Drug Transporters and Metabolizing Enzymes in the SOD1 G93A Mouse Model of Amyotrophic Lateral Sclerosis. Molecular pharmaceutics (2024)
Pok Man Leung, Rhys W Grinter, Eve Tudor-Matthew, James P Lingford, Luis Jimenez, Han-Chung Lee, Michael Milton, Iresha Hanchapola, Erwin Tanuwidjaya, Ashleigh Kropp, Hanna A Peach, Carlo R Carere, Matthew B Stott, Ralf Bernd Schittenhelm, Chris Greening
Trace gas oxidation sustains energy needs of a thermophilic archaeon at suboptimal temperatures. Nature communications 15 (1) (2024)
Matthew D Blunt, Hayden Fisher, Ralf Bernd Schittenhelm, Berenice Mbiribindi, Rebecca Fulton, Sajida Khan, Laura Espana-Serrano, Lara V Graham, Leidy Bastidas-Legarda, Daniel Burns, Sophie M S Khakoo, Salah Mansour, Jonathan W Essex, Rochelle Ayala, Jayajit Das, Anthony Wayne Purcell, Salim I Khakoo
The nuclear export protein XPO1 provides a peptide ligand for natural killer cells. Science advances 10 (34) (2024)
Matthew D Blunt, Hayden Fisher, Ralf Bernd Schittenhelm, Berenice Mbiribindi, Rebecca Fulton, Sajida Khan, Laura Espana-Serrano, Lara V Graham, Leidy Bastidas-Legarda, Daniel Burns, Sophie M S Khakoo, Salah Mansour, Jonathan W Essex, Rochelle Ayala, Jayajit Das, Anthony Wayne Purcell, Salim I Khakoo
The nuclear export protein XPO1 provides a peptide ligand for natural killer cells. Science advances 10 (34) (2024)
Yi Hsiao, Haijian Zhang, Ginny Xiaohe Li, Yamei Deng, Fengchao Yu, Hossein Valipour Kahrood, Joel Ricky Steele, Ralf Bernd Schittenhelm, Alexey I Nesvizhskii
Analysis and Visualization of Quantitative Proteomics Data Using FragPipe-Analyst. Journal of proteome research (2024)
Keith Siew, Kevin A Nestler, Charlotte A Nelson, Viola D'Ambrosio, Chutong Zhong, Zhongwang Li, Alessandra Grillo, Elizabeth R Wan, Vaksha Patel, Eliah G Overbey, Jang-Keun Kim, Sanghee Yun, Michael B Vaughan, Chris Cheshire, Laura Cubitt, Jessica Broni-Tabi, Maneera Yousef Al-Jaber, Valery Boyko, Cem Meydan, Peter Barker, Shehbeel Arif, Fatemeh Afsari, Noah Allen, Mohammed Al-Maadheed, Selin Altinok, Nourdine Bah, Samuel Border, Amanda L Brown, Keith Burling, Margareth Cheng-Campbell, Lorianna M Colón, Lovorka Degoricija, Nichola Figg, Rebecca Finch, Jonathan Foox, Pouya Faridi, Alison French, Samrawit Gebre, Peter Gordon, Nadia Houerbi, Hossein Valipour Kahrood, Frederico C Kiffer, Aleksandra S Klosinska, Angela Kubik, Han-Chung Lee, Yinghui Li, Nicholas Lucarelli, Anthony L Marullo, Irina R Matei, Colleen M McCann, Sayat Mimar, Ahmed Naglah, Jérôme Nicod, Kevin M O'Shaughnessy, Lorraine Christine De Oliveira, Leah E Oswalt, Laura Ioana Patras, San-Huei Lai Polo, Maria Rodriguez-Lopez, Candice A Roufosse, Omid Sadeghi-Alavijeh, Rebekah Sanchez-Hodge, Anindya S Paul, Ralf Bernd Schittenhelm, Annalise Schweickart, Ryan T Scott, Terry Chin Choy Lim Kam Sian, Willian A da Silveira, Hubert Slawinski, Daniel Snell, Julio Sosa, Amanda M Saravia-Butler, Marshall Tabetah, Erwin Tanuwidjaya, Simon Walker-Samuel, Xiaoping Yang, null Yasmin, Haijian Zhang, Jasminka Godovac-Zimmermann, Pinaki Sarder, Lauren M Sanders, Sylvain V Costes, Robert A A Campbell, Fathi Karouia, Vidya Mohamed-Alis, Samuel Rodriques, Steven Lynham, Joel Ricky Steele, Sergio E Baranzini, Hossein Fazelinia, Zhongquan Dai, Akira Uruno, Dai Shiba, Masayuki Yamamoto, Eduardo A C Almeida, Elizabeth Blaber, Jonathan C Schisler, Amelia J Eisch, Masafumi Muratani, Sara R Zwart, Scott M Smith, Jonathan M Galazka, Christopher E Mason, Afshin Behesti, Stephen B Walsh
Cosmic kidney disease: an integrated pan-omic, physiological and morphological study into spaceflight-induced renal dysfunction. Nature communications 15 (1) (2024)
Rhys W Grinter, Ashleigh Kropp, Hari Venugopal, Moritz Senger, Jack Badley, Princess R Cabotaje, Ruyu Jia, Zehui Duan, Ping Huang, Sven Timo Stripp, Christopher K Barlow, Matthew Belousoff, Hannah S Shafaat, Gregory M Cook, Ralf Bernd Schittenhelm, Kylie A Vincent, Syma Khalid, Gustav Berggren, Chris Greening
Structural basis for bacterial energy extraction from atmospheric hydrogen. Nature 615 (7952) (2023)
Rhys W Grinter, Ashleigh Kropp, Hari Venugopal, Moritz Senger, Jack Badley, Princess R Cabotaje, Ruyu Jia, Zehui Duan, Ping Huang, Sven Timo Stripp, Christopher K Barlow, Matthew Belousoff, Hannah S Shafaat, Gregory M Cook, Ralf Bernd Schittenhelm, Kylie A Vincent, Syma Khalid, Gustav Berggren, Chris Greening
Structural basis for bacterial energy extraction from atmospheric hydrogen. Nature 615 (7952) (2023)
Connie Fung, Brendan Wilding, Ralf Bernd Schittenhelm, Robert J Bryson-Richardson, Phillip I Bird
Expression of the Z Variant of α1-Antitrypsin Suppresses Hepatic Cholesterol Biosynthesis in Transgenic Zebrafish. International journal of molecular sciences 24 (3) (2023)
Joshua N Johnstone, Christen Kerry Mirth, Travis K Johnson, Ralf Bernd Schittenhelm, Matthew W D Piper
GCN2 mediates access to stored amino acids for somatic maintenance during Drosophila ageing. bioRxiv : the preprint server for biology (2023)
Rhys W Grinter, Ashleigh Kropp, Hari Venugopal, Moritz Senger, Jack Badley, Princess R Cabotaje, Ruyu Jia, Zehui Duan, Ping Huang, Sven Timo Stripp, Christopher K Barlow, Matthew Belousoff, Hannah S Shafaat, Gregory M Cook, Ralf Bernd Schittenhelm, Kylie A Vincent, Syma Khalid, Gustav Berggren, Chris Greening
Structural basis for bacterial energy extraction from atmospheric hydrogen. Nature (2023)
Xue Yang, Miguel I Cruz, Elizabeth V Nguyen, Cheng Huang, Ralf Bernd Schittenhelm, Jennii Luu, Karla J Cowley, Sung-Young Shin, Lan K Nguyen, Terry Chin Choy Lim Kam Sian, Kimberley C Clark, Kaylene J Simpson, Xiuquan Ma, Roger J Daly
The pseudokinase NRBP1 activates Rac1/Cdc42 via P-Rex1 to drive oncogenic signalling in triple-negative breast cancer. Oncogene 42 (11) (2023)
Louise Uoselis, Runa S J Lindblom, Wai Kit Lam, Catharina J Küng, Marvin Skulsuppaisarn, Grace Khuu, Thanh Ngoc Nguyen, Danielle L Rudler, Aleksandra Filipovska, Ralf Bernd Schittenhelm, Michael Lazarou
Temporal landscape of mitochondrial proteostasis governed by the UPR mt . Science advances 9 (38) (2023)
Connie Fung, Brendan Wilding, Ralf Bernd Schittenhelm, Robert J Bryson-Richardson, Phillip I Bird
Expression of the Z Variant of α1-Antitrypsin Suppresses Hepatic Cholesterol Biosynthesis in Transgenic Zebrafish. International journal of molecular sciences 24 (3) (2023)
Xue Yang, Miguel I Cruz, Elizabeth V Nguyen, Cheng Huang, Ralf Bernd Schittenhelm, Jennii Luu, Karla J Cowley, Sung-Young Shin, Lan K Nguyen, Terry Chin Choy Lim Kam Sian, Kimberley C Clark, Kaylene J Simpson, Xiuquan Ma, Roger J Daly
The pseudokinase NRBP1 activates Rac1/Cdc42 via P-Rex1 to drive oncogenic signalling in triple-negative breast cancer. Oncogene 42 (11) (2023)
Macsue Jacques, Shanie Landen, Javier Alvarez Romero, Danielle Hiam, Ralf Bernd Schittenhelm, Iresha Hanchapola, Anup D Shah, Sarah Voisin, Nir Eynon
Methylome and proteome integration in human skeletal muscle uncover group and individual responses to high-intensity interval training. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 37 (10) (2023)
Xue Yang, Miguel I Cruz, Elizabeth V Nguyen, Cheng Huang, Ralf Bernd Schittenhelm, Jennii Luu, Karla J Cowley, Sung-Young Shin, Lan K Nguyen, Terry Chin Choy Lim Kam Sian, Kimberley C Clark, Kaylene J Simpson, Xiuquan Ma, Roger J Daly
The pseudokinase NRBP1 activates Rac1/Cdc42 via P-Rex1 to drive oncogenic signalling in triple-negative breast cancer. Oncogene (2023)
Andre Mu, William P Klare, Sarah L Baines, Chi Nam Ignatius Pang, Romain J R Guérillot, Nichaela Harbison-Price, Nadia Keller, Jonathan Wilksch, Nguyen Thi Khanh Nhu, Minh Duy Phan, Bernhard Keller, Brunda Nijagal, Dedreia Tull, Saravanan Dayalan, Hwa Huat Charlie Chua, Dominik Skoneczny, Jason Koval, Abderrahman Hachani, Anup D Shah, Nitika Neha, Snehal Jadhav, Sally R Partridge, Amanda J Cork, Kate Peters, Olivia Bertolla, Stephan Brouwer, Steven J Hancock, Laura Alvarez-Fraga, David M P De Oliveira, Brian M Forde, Ashleigh Dale, Warasinee Mujchariyakul, Calum J Walsh, Ian R Monk, Anna Fitzgerald, Mabel Lum, Carolina Correa-Ospina, Piklu Roy Chowdhury, Robert G Parton, James J De Voss, James Beckett, Francois Monty, Jessica McKinnon, Xiaomin Song, John R Stephen, Marie Everest, Matthew I Bellgard, Matthew Tinning, Michael Leeming, Dianna M Hocking, Leila Jebeli, Nancy Wang, Nouri L Ben Zakour, Serhat A Yasar, Stefano Vecchiarelli, Tonia Russell, Thiri Zaw, Tyrone Chen, Don Teng, Zena Kassir, Trevor J Lithgow, Adam Jenney, Jason N Cole, Victor Nizet, Tania C Sorrell, Anton Y Peleg, David L Paterson, Scott A Beatson, Jemma Wu, Mark P Molloy, Anna E Syme, Robert J A Goode, Adam A Hunter, Grahame Bowland, Nicholas P West, Marc R Wilkins, Steven Philip Djordjevic, Mark R Davies, Torsten Seemann, Benjamin Peter Howden, Dana Pascovici, Sonika Tyagi, Ralf Bernd Schittenhelm, David P de Souza, Malcolm J McConville, Jonathan R Iredell, Stuart J Cordwell, Richard A Strugnell, Timothy P Stinear, Mark A Schembri, Mark J Walker
Integrative omics identifies conserved and pathogen-specific responses of sepsis-causing bacteria. Nature communications 14 (1) (2023)
Rhys W Grinter, Ashleigh Kropp, Hari Venugopal, Moritz Senger, Jack Badley, Princess R Cabotaje, Ruyu Jia, Zehui Duan, Ping Huang, Sven Timo Stripp, Christopher K Barlow, Matthew Belousoff, Hannah S Shafaat, Gregory M Cook, Ralf Bernd Schittenhelm, Kylie A Vincent, Syma Khalid, Gustav Berggren, Chris Greening
Structural basis for bacterial energy extraction from atmospheric hydrogen. Nature 615 (7952) (2023)
Haijian Zhang, Joel Ricky Steele, Hossein Valipour Kahrood, Deanna Deveson Lucas, Anup D Shah, Ralf Bernd Schittenhelm
Phospho-Analyst: An Interactive, Easy-to-Use Web Platform To Analyze Quantitative Phosphoproteomics Data. Journal of proteome research (2023)
Rhys W Grinter, Ashleigh Kropp, Hari Venugopal, Moritz Senger, Jack Badley, Princess R Cabotaje, Ruyu Jia, Zehui Duan, Ping Huang, Sven Timo Stripp, Christopher K Barlow, Matthew Belousoff, Hannah S Shafaat, Gregory M Cook, Ralf Bernd Schittenhelm, Kylie A Vincent, Syma Khalid, Gustav Berggren, Chris Greening
Structural basis for bacterial energy extraction from atmospheric hydrogen. Nature 615 (7952) (2023)
Xue Yang, Miguel I Cruz, Elizabeth V Nguyen, Cheng Huang, Ralf Bernd Schittenhelm, Jennii Luu, Karla J Cowley, Sung-Young Shin, Lan K Nguyen, Terry Chin Choy Lim Kam Sian, Kimberley C Clark, Kaylene J Simpson, Xiuquan Ma, Roger J Daly
The pseudokinase NRBP1 activates Rac1/Cdc42 via P-Rex1 to drive oncogenic signalling in triple-negative breast cancer. Oncogene (2023)
Katie L Ayers, Stefanie Eggers, Ben N Rollo, Katherine R Smith, Nadia M Davidson, Nicole A Siddall, Liang Zhao, Josephine Bowles, Karin Weiss, Ginevra Zanni, Lydie Burglen, Shay Ben-Shachar, Jenny Rosensaft, Annick Raas-Rothschild, Anne Jørgensen, Ralf Bernd Schittenhelm, Cheng Huang, Gorjana Robevska, Jocelyn van den Bergen, Franca Casagranda, Justyna Cyza, Svenja Pachernegg, David K Wright, Melanie Bahlo, Alicia Oshlack, Terrence J O'Brien, Patrick Kwan, Peter Koopman, Gary R Hime, Nadine Girard, Chen Hoffmann, Yuval Shilon, Amnon Zung, Enrico Bertini, Mathieu Milh, Bochra Ben Rhouma, Neila Belguith, Anu Bashamboo, Kenneth MacElreavey, Ehud Banne, Naomi Weintrob, Bruria BenZeev, Andrew H Sinclair
Variants in SART3 cause a spliceosomopathy characterised by failure of testis development and neuronal defects. Nature communications 14 (1) (2023)
Xue Yang, Miguel I Cruz, Elizabeth V Nguyen, Cheng Huang, Ralf Bernd Schittenhelm, Jennii Luu, Karla J Cowley, Sung-Young Shin, Lan K Nguyen, Terry Chin Choy Lim Kam Sian, Kimberley C Clark, Kaylene J Simpson, Xiuquan Ma, Roger J Daly
The pseudokinase NRBP1 activates Rac1/Cdc42 via P-Rex1 to drive oncogenic signalling in triple-negative breast cancer. Oncogene 42 (11) (2023)
Connie Fung, Brendan Wilding, Ralf Bernd Schittenhelm, Robert J Bryson-Richardson, Phillip I Bird
Expression of the Z Variant of α1-Antitrypsin Suppresses Hepatic Cholesterol Biosynthesis in Transgenic Zebrafish. International journal of molecular sciences 24 (3) (2023)
Andre Mu, William P Klare, Sarah L Baines, Chi Nam Ignatius Pang, Romain J R Guérillot, Nichaela Harbison-Price, Nadia Keller, Jonathan Wilksch, Nguyen Thi Khanh Nhu, Minh Duy Phan, Bernhard Keller, Brunda Nijagal, Dedreia Tull, Saravanan Dayalan, Hwa Huat Charlie Chua, Dominik Skoneczny, Jason Koval, Abderrahman Hachani, Anup D Shah, Nitika Neha, Snehal Jadhav, Sally R Partridge, Amanda J Cork, Kate Peters, Olivia Bertolla, Stephan Brouwer, Steven J Hancock, Laura Alvarez-Fraga, David M P De Oliveira, Brian M Forde, Ashleigh Dale, Warasinee Mujchariyakul, Calum J Walsh, Ian R Monk, Anna Fitzgerald, Mabel Lum, Carolina Correa-Ospina, Piklu Roy Chowdhury, Robert G Parton, James J De Voss, James Beckett, Francois Monty, Jessica McKinnon, Xiaomin Song, John R Stephen, Marie Everest, Matthew I Bellgard, Matthew Tinning, Michael Leeming, Dianna M Hocking, Leila Jebeli, Nancy Wang, Nouri L Ben Zakour, Serhat A Yasar, Stefano Vecchiarelli, Tonia Russell, Thiri Zaw, Tyrone Chen, Don Teng, Zena Kassir, Trevor J Lithgow, Adam Jenney, Jason N Cole, Victor Nizet, Tania C Sorrell, Anton Y Peleg, David L Paterson, Scott A Beatson, Jemma Wu, Mark P Molloy, Anna E Syme, Robert J A Goode, Adam A Hunter, Grahame Bowland, Nicholas P West, Marc R Wilkins, Steven Philip Djordjevic, Mark R Davies, Torsten Seemann, Benjamin Peter Howden, Dana Pascovici, Sonika Tyagi, Ralf Bernd Schittenhelm, David P de Souza, Malcolm J McConville, Jonathan R Iredell, Stuart J Cordwell, Richard A Strugnell, Timothy P Stinear, Mark A Schembri, Mark J Walker
Integrative omics identifies conserved and pathogen-specific responses of sepsis-causing bacteria. Nature communications 14 (1) (2023)
Xue Yang, Miguel I Cruz, Elizabeth V Nguyen, Cheng Huang, Ralf Bernd Schittenhelm, Jennii Luu, Karla J Cowley, Sung-Young Shin, Lan K Nguyen, Terry Chin Choy Lim Kam Sian, Kimberley C Clark, Kaylene J Simpson, Xiuquan Ma, Roger J Daly
The pseudokinase NRBP1 activates Rac1/Cdc42 via P-Rex1 to drive oncogenic signalling in triple-negative breast cancer. Oncogene 42 (11) (2023)
Andre Mu, William P Klare, Sarah L Baines, Chi Nam Ignatius Pang, Romain J R Guérillot, Nichaela Harbison-Price, Nadia Keller, Jonathan Wilksch, Nguyen Thi Khanh Nhu, Minh Duy Phan, Bernhard Keller, Brunda Nijagal, Dedreia Tull, Saravanan Dayalan, Hwa Huat Charlie Chua, Dominik Skoneczny, Jason Koval, Abderrahman Hachani, Anup D Shah, Nitika Neha, Snehal Jadhav, Sally R Partridge, Amanda J Cork, Kate Peters, Olivia Bertolla, Stephan Brouwer, Steven J Hancock, Laura Alvarez-Fraga, David M P De Oliveira, Brian M Forde, Ashleigh Dale, Warasinee Mujchariyakul, Calum J Walsh, Ian R Monk, Anna Fitzgerald, Mabel Lum, Carolina Correa-Ospina, Piklu Roy Chowdhury, Robert G Parton, James J De Voss, James Beckett, Francois Monty, Jessica McKinnon, Xiaomin Song, John R Stephen, Marie Everest, Matthew I Bellgard, Matthew Tinning, Michael Leeming, Dianna M Hocking, Leila Jebeli, Nancy Wang, Nouri L Ben Zakour, Serhat A Yasar, Stefano Vecchiarelli, Tonia Russell, Thiri Zaw, Tyrone Chen, Don Teng, Zena Kassir, Trevor J Lithgow, Adam Jenney, Jason N Cole, Victor Nizet, Tania C Sorrell, Anton Y Peleg, David L Paterson, Scott A Beatson, Jemma Wu, Mark P Molloy, Anna E Syme, Robert J A Goode, Adam A Hunter, Grahame Bowland, Nicholas P West, Marc R Wilkins, Steven Philip Djordjevic, Mark R Davies, Torsten Seemann, Benjamin Peter Howden, Dana Pascovici, Sonika Tyagi, Ralf Bernd Schittenhelm, David P de Souza, Malcolm J McConville, Jonathan R Iredell, Stuart J Cordwell, Richard A Strugnell, Timothy P Stinear, Mark A Schembri, Mark J Walker
Integrative omics identifies conserved and pathogen-specific responses of sepsis-causing bacteria. Nature communications 14 (1) (2023)
Connie Fung, Brendan Wilding, Ralf Bernd Schittenhelm, Robert J Bryson-Richardson, Phillip I Bird
Expression of the Z Variant of α1-Antitrypsin Suppresses Hepatic Cholesterol Biosynthesis in Transgenic Zebrafish. International journal of molecular sciences 24 (3) (2023)
Gamze Kuser-Abali, Youfang Zhang, Pacman Szeto, Peinan Zhao, Samar Masoumi-Moghaddam, Clare G Fedele, Isobel Leece, Cheng Huang, Jen G Cheung, Malaka Ameratunga, Fumihito Noguchi, Miles C Andrews, Nicholas C Wong, Ralf Bernd Schittenhelm, Mark Shackleton
UHRF1/UBE2L6/UBR4-mediated ubiquitination regulates EZH2 abundance and thereby melanocytic differentiation phenotypes in melanoma. Oncogene (2023)
Katie L Ayers, Stefanie Eggers, Ben N Rollo, Katherine R Smith, Nadia M Davidson, Nicole A Siddall, Liang Zhao, Josephine Bowles, Karin Weiss, Ginevra Zanni, Lydie Burglen, Shay Ben-Shachar, Jenny Rosensaft, Annick Raas-Rothschild, Anne Jørgensen, Ralf Bernd Schittenhelm, Cheng Huang, Gorjana Robevska, Jocelyn van den Bergen, Franca Casagranda, Justyna Cyza, Svenja Pachernegg, David K Wright, Melanie Bahlo, Alicia Oshlack, Terrence J O'Brien, Patrick Kwan, Peter Koopman, Gary R Hime, Nadine Girard, Chen Hoffmann, Yuval Shilon, Amnon Zung, Enrico Bertini, Mathieu Milh, Bochra Ben Rhouma, Neila Belguith, Anu Bashamboo, Kenneth McElreavey, Ehud Banne, Naomi Weintrob, Bruria BenZeev, Andrew H Sinclair
Author Correction: Variants in SART3 cause a spliceosomopathy characterised by failure of testis development and neuronal defects. Nature communications 14 (1) (2023)
Pok Man Leung, Anne Daebeler, Eleonora Chiri, Iresha Hanchapola, David L Gillett, Ralf Bernd Schittenhelm, Holger Daims, Chris Greening
A nitrite-oxidising bacterium constitutively consumes atmospheric hydrogen. The ISME journal 16 (9) (2022)
Yijun Pan, Yoshiteru Kagawa, Jiaqi Sun, Bradley J Turner, Cheng Huang, Anup D Shah, Ralf Bernd Schittenhelm, Joseph A Nicolazzo
Altered Blood-Brain Barrier Dynamics in the C9orf72 Hexanucleotide Repeat Expansion Mouse Model of Amyotrophic Lateral Sclerosis. Pharmaceutics 14 (12) (2022)
Anna Harutyunyan, Debbie Chong, Rui Li, Anup D Shah, Zahra Ali, Cheng Huang, Christopher K Barlow, Piero Perucca, Terence J O'Brien, Nigel Charles Jones, Ralf Bernd Schittenhelm, Alison Anderson, Pablo M Casillas-Espinosa
An Integrated Multi-Omic Network Analysis Identifies Seizure-Associated Dysregulated Pathways in the GAERS Model of Absence Epilepsy. International journal of molecular sciences 23 (11) (2022)
Ghizal Siddiqui, Amanda De Paoli, Christopher A MacRaild, Anna E Sexton, Coralie Boulet, Anup D Shah, Mitchell B Batty, Ralf Bernd Schittenhelm, Teresa G Carvalho, Darren John Creek
A new mass spectral library for high-coverage and reproducible analysis of the Plasmodium falciparum-infected red blood cell proteome. GigaScience 11 (2022)
Yijun Pan, Yoshiteru Kagawa, Jiaqi Sun, Bradley J Turner, Cheng Huang, Anup D Shah, Ralf Bernd Schittenhelm, Joseph A Nicolazzo
Altered Blood-Brain Barrier Dynamics in the C9orf72 Hexanucleotide Repeat Expansion Mouse Model of Amyotrophic Lateral Sclerosis. Pharmaceutics 14 (12) (2022)
Yong-Gang Chang, Christopher J Lupton, Charles Bayly-Jones, Alastair C Keen, Laura D'Andrea, Christina M Lucato, Joel Ricky Steele, Hari Venugopal, Ralf Bernd Schittenhelm, James C Whisstock, Michelle L Halls, Andrew M Ellisdon
Structure of the metastatic factor P-Rex1 reveals a two-layered autoinhibitory mechanism. Nature structural & molecular biology 29 (8) (2022)
Yijun Pan, Yoshiteru Kagawa, Jiaqi Sun, Bradley J Turner, Cheng Huang, Anup D Shah, Ralf Bernd Schittenhelm, Joseph A Nicolazzo
Altered Blood-Brain Barrier Dynamics in the C9orf72 Hexanucleotide Repeat Expansion Mouse Model of Amyotrophic Lateral Sclerosis. Pharmaceutics 14 (12) (2022)
Yijun Pan, Yoshiteru Kagawa, Jiaqi Sun, Bradley J Turner, Cheng Huang, Anup D Shah, Ralf Bernd Schittenhelm, Joseph A Nicolazzo
Altered Blood-Brain Barrier Dynamics in the C9orf72 Hexanucleotide Repeat Expansion Mouse Model of Amyotrophic Lateral Sclerosis. Pharmaceutics 14 (12) (2022)
Magdalene K Montgomery, Jacqueline Bayliss, Shuai Nie, William De Nardo, Stacey N Keenan, Paula M Miotto, Hamzeh Karimkhanloo, Cheng Huang, Ralf Bernd Schittenhelm, Anthony S Don, Andrew Ryan, Nicholas A Williamson, Geraldine J Ooi, Wendy A Brown, Paul R Burton, Benjamin L Parker, Matthew J Watt
Deep proteomic profiling unveils arylsulfatase A as a non-alcoholic steatohepatitis inducible hepatokine and regulator of glycemic control. Nature communications 13 (1) (2022)
Thierry Izoré, Y T Candace Ho, Joe A Kaczmarski, Athina Gavriilidou, Ka Ho Chow, David L Steer, Robert J A Goode, Ralf Bernd Schittenhelm, Julien Tailhades, Manuela Tosin, Gregory L Challis, Elizabeth H Krenske, Nadine Ziemert, Colin J Jackson, Max J Cryle
Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity. Nature communications 12 (1) (2021)
Chrysovalantou E Xirouchaki, Yaoyao Jia, Meagan J McGrath, Spencer Greatorex, Melanie Tran, Troy L Merry, Dawn Hong, Matthew J Eramo, Sophie C Broome, Jonathan S T Woodhead, Randall F D'souza, Jenny Gallagher, Ekaterina Salimova, Cheng Huang, Ralf Bernd Schittenhelm, Junichi Sadoshima, Matthew J Watt, Christina A Mitchell, Tony Tiganis
Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance. Science advances 7 (51) (2021)
Linda K H Teng, Brooke A Pereira, Shivakumar Keerthikumar, Cheng Huang, Birunthi Niranjan, Sophie N Lee, Michelle Richards, Ralf Bernd Schittenhelm, Luc Furic, David L Goode, Mitchell G Lawrence, Renea A Taylor, Stuart J Ellem, Gail P Risbridger, Natalie L Lister
Mast Cell-Derived SAMD14 Is a Novel Regulator of the Human Prostate Tumor Microenvironment. Cancers 13 (6) (2021)
Flavia Santamaria, Christopher K Barlow, Rolf Schlagloth, Ralf Bernd Schittenhelm, Rupert Palme, Joerg Henning
Identification of Koala (Phascolarctos cinereus) Faecal Cortisol Metabolites Using Liquid Chromatography-Mass Spectrometry and Enzyme Immunoassays. Metabolites 11 (6) (2021)
Samuel J Rodgers, Lisa M Ooms, Viola M J Oorschot, Ralf Bernd Schittenhelm, Elizabeth V Nguyen, Sabryn A Hamila, Natalie Rynkiewicz, Rajendra Gurung, Matthew J Eramo, Absorn Sriratana, Clare G Fedele, Franco Caramia, Sherene Loi, Genevieve Kerr, Helen E Abud, Georg Ramm, Antonella Papa, Andrew M Ellisdon, Roger J Daly, Catriona A Mclean, Christina A Mitchell
INPP4B promotes PI3Kα-dependent late endosome formation and Wnt/β-catenin signaling in breast cancer. Nature communications 12 (1) (2021)
Anbarasu Karthikaichamy, John Beardall, Ross Coppel, Santosh Noronha, Dieter Bulach, Ralf Bernd Schittenhelm, Sandip Kumar Patel
Data-Independent-Acquisition-Based Proteomic Approach towards Understanding the Acclimation Strategy of Oleaginous Microalga Microchloropsis gaditana CCMP526 in Hypersaline Conditions. ACS omega 6 (34) (2021)
Jennifer A E Payne, Julien Tailhades, Felix Ellett, Xenia Kostoulias, Alex J Fulcher, Ting Fu, Ryan Leung, Stephanie Louch, Amy Tran, Severin A Weber, Ralf Bernd Schittenhelm, Graham J Lieschke, Chengxue Helena Qin, Daniel Irima, Anton Y Peleg, Max J Cryle
Antibiotic-chemoattractants enhance neutrophil clearance of Staphylococcus aureus. Nature communications 12 (1) (2021)
Christopher J Lupton, Charles Bayly-Jones, Laura D'Andrea, Cheng Huang, Ralf Bernd Schittenhelm, Hari Venugopal, James C Whisstock, Michelle L Halls, Andrew M Ellisdon
The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1. Nature structural & molecular biology 28 (12) (2021)
Magdalene K Montgomery, Jacqueline Bayliss, Camille J Devereux, Ayenachew Bezawork-Geleta, David Roberts, Cheng Huang, Ralf Bernd Schittenhelm, Andrew Ryan, Scott L Townley, Luke A Selth, Trevor J Biden, Gregory R Steinberg, Dorit Samocha-Bonet, Ruth C R Meex, Matthew J Watt
SMOC1 is a glucose-responsive hepatokine and therapeutic target for glycemic control. Science translational medicine 12 (559) (2021)
Milda Kaniusaite, Tiia Kittilä, Robert J A Goode, Ralf Bernd Schittenhelm, Max J Cryle
Redesign of Substrate Selection in Glycopeptide Antibiotic Biosynthesis Enables Effective Formation of Alternate Peptide Backbones. ACS chemical biology 15 (9) (2020)
Milda Kaniusaite, Robert J A Goode, Julien Tailhades, Ralf Bernd Schittenhelm, Max J Cryle
Exploring modular reengineering strategies to redesign the teicoplanin non-ribosomal peptide synthetase. Chemical science 11 (35) (2020)
Pankaj Deo, Seong Hoong Chow, Mei-Ling Han, Mary Speir, Cheng Huang, Ralf Bernd Schittenhelm, Subhash Dhital, Jack Emery, Jian Li, Benjamin T Kile, James E Vince, Kate E Lawlor, Thomas Naderer
Mitochondrial dysfunction caused by outer membrane vesicles from Gram-negative bacteria activates intrinsic apoptosis and inflammation. Nature microbiology 5 (11) (2020)
Yann W Yap, Patricia M Rusu, Andrea Y Chan, Barbara C Fam, Andreas Jungmann, Samantha M Solon-Biet, Christopher K Barlow, Darren J Creek, Cheng Huang, Ralf Bernd Schittenhelm, Bruce Morgan, Dieter Schmoll, Bente Kiens, Matthew D W Piper, Mathias Heikenwälder, Stephen James Simpson, Stefan Broer, Sofianos Andrikopoulos, Oliver J Müller, Adam J Rose
Restriction of essential amino acids dictates the systemic metabolic response to dietary protein dilution. Nature communications 11 (1) (2020)
Matthew J Watt, Ashlee K Clark, Luke A Selth, Vanessa R Haynes, Natalie Lister, Richard J Rebello, Laura H Porter, Birunthi Niranjan, Sarah T Whitby, Jennifer Lo, Cheng Huang, Ralf Bernd Schittenhelm, Kimberley E Anderson, Luc Furic, Poornima R Wijayaratne, Maria Matzaris, Magdalene K Montgomery, Melissa Papargiris, Sam Norden, Maria Febbraio, Gail P Risbridger, Mark Frydenberg, Daniel K Nomura, Renea A Taylor
Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer. Science translational medicine 11 (478) (2020)
Vinutha K Balachandra, Jiyoti Verma, Madhu Shankar, Timothy M Tucey, Ana Traven, Ralf Bernd Schittenhelm, Santanu Kumar Ghosh
The RSC (Remodels the Structure of Chromatin) complex of Candida albicans shows compositional divergence with distinct roles in regulating pathogenic traits. PLoS genetics 16 (11) (2020)
Pouya Faridi, Katherine Woods, Simone Ostrouska, Cyril Deceneux, Ritchlynn Aranha, Divya Duscharla, Stephen Q Wong, Weisan Chen, Sri H Ramarathinam, Terry C C Lim Kam Sian, Nathan Paul Croft, Chen Li, Rochelle Ayala, Jonathan S Cebon, Anthony Wayne Purcell, Ralf Bernd Schittenhelm, Andreas Behren
Spliced Peptides and Cytokine-Driven Changes in the Immunopeptidome of Melanoma. Cancer immunology research 8 (10) (2020)
Julien Tailhades, Yongwei Zhao, Y T Candace Ho, Anja Greule, Iftekhar Ahmed, Melanie Schoppet, Ketav Kulkarni, Rob J A Goode, Ralf Bernd Schittenhelm, James J De Voss, Max J Cryle
A Chemoenzymatic Approach to the Synthesis of Glycopeptide Antibiotic Analogues. Angewandte Chemie (International ed. in English) 59 (27) (2020)
Cheng Huang, Simon R Foster, Anup D Shah, Oded Kleifeld, Meritxell Canals, Ralf Bernd Schittenhelm, Richard J Payne
Phosphoproteomic characterization of the signaling network resulting from activation of the chemokine receptor CCR2. The Journal of biological chemistry 295 (19) (2020)
Julien Tailhades, Yongwei Zhao, Melanie Schoppet, Anja Greule, Robert J A Goode, Ralf Bernd Schittenhelm, James J De Voss, Max J Cryle
Enzymatic Cascade To Evaluate the Tricyclization of Glycopeptide Antibiotic Precursor Peptides as a Prequel to Biosynthetic Redesign. Organic letters 21 (21) (2019)
Anup D Shah, Robert J A Goode, Cheng Huang, David R Powell, Ralf Bernd Schittenhelm
LFQ-Analyst: An Easy-To-Use Interactive Web Platform To Analyze and Visualize Label-Free Proteomics Data Preprocessed with MaxQuant. Journal of proteome research 19 (1) (2019)
Yongwei Zhao, Robert J A Goode, Ralf Bernd Schittenhelm, Julien Tailhades, Max J Cryle
Exploring the Tetracyclization of Teicoplanin Precursor Peptides through Chemoenzymatic Synthesis. The Journal of organic chemistry 85 (3) (2019)
Srgjan Civciristov, Cheng Huang, Bonan Liu, Elsa A Marquez, Arisbel B Gondin, Ralf Bernd Schittenhelm, Andrew M Ellisdon, Meritxell Canals, Michelle L Halls
Ligand-dependent spatiotemporal signaling profiles of the μ-opioid receptor are controlled by distinct protein-interaction networks. The Journal of biological chemistry 294 (44) (2019)
Milda Kaniusaite, Robert J A Goode, Ralf Bernd Schittenhelm, Thomas M Makris, Max J Cryle
The Diiron Monooxygenase CmlA from Chloramphenicol Biosynthesis Allows Reconstitution of β-Hydroxylation during Glycopeptide Antibiotic Biosynthesis. ACS chemical biology 14 (12) (2019)
Terry Chin Choy Lim Kam Sian, Saranjah Indumathy, Hanim Halim, Anja Greule, Max J Cryle, Paul Bowness, Jamie Rossjohn, Stephanie Gras, Anthony Wayne Purcell, Ralf Bernd Schittenhelm
Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation. The Journal of biological chemistry 294 (52) (2019)