Steven A Johnsen

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 34

Top Venues

Cancers

Cell death & disease

Cell death and differentiation

Science immunology

Mayo Clinic Rochester

Mayo Clinic Rochester (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Mayo Clinic Rochester Feb 25 2019

United States

Senior Associate Consultant II :: Division of Gastroenterology and Hepatology

University Medical Center Göttingen Apr 01 2014 - Feb 28 2019

Germany

Full Professor for Translational Cancer Research :: General, Visceral & Pediatric Surgery

University Hospital Hamburg-Eppendorf Apr 01 2012 - Mar 31 2014

Germany

Associate Professor for Tumor Biology :: Department of Tumor Biology

University Medical Center Göttingen Jun 01 2007 - Mar 31 2012

Germany

Assistant Professor of Molecular Oncology :: Department of Molecular Oncology

European Molecular Biology Laboratory Jan 04 2006 - May 30 2007

Germany

Post-doctoral Fellow :: Director's Research (Frank Gannon Group)

Education History

Mayo Clinic Rochester Jun 07 1999 - Dec 22 2002

United States

PHD :: Biochemistry & Molecular Biology

Publications

Thomas L Ekstrom, Sajjad Hussain, Tibor Bedekovics, Asma Ali, Lucia Paolini, Hina Mahmood, Raya M Rosok, Jan Koster, Steven A Johnsen, Paul J Galardy
USP44 overexpression drives a MYC-like gene expression program in neuroblastoma through epigenetic reprogramming. Molecular cancer research : MCR (2024)
Xin Wang, Ana Patricia Kutschat, Joana Aggrey-Fynn, Feda H Hamdan, Rondell P Graham, Alexander Q Wixom, Yara Souto, Swetlana Ladigan-Badura, Jennifer A Yonkus, Amro M Abdelrahman, Roberto Alva-Ruiz, Jochen Gaedcke, Philipp Stroebel, Robyn Laura Kosinsky, Florian Wegwitz, Patrick Christian Hermann, Mark J Truty, Jens Thomas Siveke, Stephan A Hahn, Elisabeth Hessmann, Steven A Johnsen, Zeynab Najafova
Identification of a ΔNp63-Dependent Basal-Like A Subtype-Specific Transcribed Enhancer Program (B-STEP) in Aggressive Pancreatic Ductal Adenocarcinoma. Molecular cancer research : MCR (2023)
Evangelos Prokakis, Shaishavi Jansari, Angela Boshnakovska, Maria Wiese, Kathrin Kusch, Christof Maria Kramm, Christian Dullin, Peter Rehling, Markus Glatzel, Klaus Pantel, Harriett Wikman, Steven A Johnsen, Julia Gallwas, Florian Wegwitz
RNF40 epigenetically modulates glycolysis to support the aggressiveness of basal-like breast cancer. Cell death & disease 14 (9) (2023)
Feda H Hamdan, Amro M Abdelrahman, Ana Patricia Kutschat, Xin Wang, Thomas L Ekstrom, Nidhi Jalan-Sakrikar, Catherine Wegner Wippel, Negar Taheri, Liezel Tamon, Waltraut Kopp, Joana Aggrey-Fynn, Aditya V Bhagwate, Roberto Alva-Ruiz, Isaac Lynch, Jennifer Yonkus, Robyn Laura Kosinsky, Jochen Gaedcke, Stephan A Hahn, Jens Thomas Siveke, Rondell Graham, Zeynab Najafova, Elisabeth Hessmann, Mark J Truty, Steven A Johnsen
Interactive enhancer hubs (iHUBs) mediate transcriptional reprogramming and adaptive resistance in pancreatic cancer. Gut (2023)
Kirsten G M Aspros, Jodi M Carter, Tanya L Hoskin, Vera J Suman, Malayannan Subramaniam, Michael J Emch, Zhenqing Ye, Zhifu Sun, Jason P Sinnwell, Kevin J Thompson, Xiaojia Tang, Esther P B Rodman, Xiyin Wang, Adam W Nelson, Igor Chernukhin, Feda H Hamdan, Elizabeth S Bruinsma, Jason S Carroll, Martin E Fernandez-Zapico, Steven A Johnsen, Krishna R Kalari, Zhenlin Huang, Roberto A Leon-Ferre, Fergus J Couch, James N Ingle, Matthew P Goetz, John R Hawse
Estrogen receptor beta repurposes EZH2 to suppress oncogenic NFκB/p65 signaling in triple negative breast cancer. NPJ breast cancer 8 (1) (2022)
Nikolaus Dietlein, Xi Wang, Jonas Metz, Olivier Disson, Fuwei Shang, Celine Beyersdörffer, Esther Rodríguez Correa, Daniel B Lipka, Yvonne Begus-Nahrmann, Robyn Laura Kosinsky, Steven A Johnsen, Marc Lecuit, Thomas Höfer, Hans-Reimer Rodewald
Usp22 is an intracellular regulator of systemic emergency hematopoiesis. Science immunology 7 (78) (2022)
Nikolaus Dietlein, Xi Wang, Jonas Metz, Olivier Disson, Fuwei Shang, Celine Beyersdörffer, Esther Rodríguez Correa, Daniel B Lipka, Yvonne Begus-Nahrmann, Robyn Laura Kosinsky, Steven A Johnsen, Marc Lecuit, Thomas Höfer, Hans-Reimer Rodewald
Usp22 is an intracellular regulator of systemic emergency hematopoiesis. Science immunology 7 (78) (2022)
Nikolaus Dietlein, Xi Wang, Jonas Metz, Olivier Disson, Fuwei Shang, Celine Beyersdörffer, Esther Rodríguez Correa, Daniel B Lipka, Yvonne Begus-Nahrmann, Robyn Laura Kosinsky, Steven A Johnsen, Marc Lecuit, Thomas Höfer, Hans-Reimer Rodewald
Usp22 is an intracellular regulator of systemic emergency hematopoiesis. Science immunology 7 (78) (2022)
Nikolaus Dietlein, Xi Wang, Jonas Metz, Olivier Disson, Fuwei Shang, Celine Beyersdörffer, Esther Rodríguez Correa, Daniel B Lipka, Yvonne Begus-Nahrmann, Robyn Laura Kosinsky, Steven A Johnsen, Marc Lecuit, Thomas Höfer, Hans-Reimer Rodewald
Usp22 is an intracellular regulator of systemic emergency hematopoiesis. Science immunology 7 (78) (2022)
Su Jung Oh-Hohenhorst, Derya Tilki, Ann-Kristin Ahlers, Anna Suling, Oliver Hahn, Pierre Tennstedt, Christiane Matuszcak, Hanna Maar, Vera Labitzky, Sandra Hanika, Sarah Starzonek, Simon Baumgart, Steven A Johnsen, Martina Kluth, Hüseyin Sirma, Ronald Simon, Guido Sauter, Hartwig Huland, Udo Schumacher, Tobias Lange
CHD1 loss negatively influences metastasis-free survival in R0-resected prostate cancer patients and promotes spontaneous metastasis in vivo. Cancer gene therapy (2021)
Mengfei Liu, Sheng Cao, Li He, Jinhang Gao, Juan Pablo Arab, Huarui Cui, Weixia Xuan, Yandong Gao, Tejasav S Sehrawat, Feda H Hamdan, Meritxell Ventura-Cots, Josepmaria Argemi, William C K Pomerantz, Steven A Johnsen, Jeong-Heon Lee, Fei Gao, Tamas Ordog, Philippe Mathurin, Alexander Revzin, Ramon Bataller, Huihuang Yan, Vijay H Shah
Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis. Nature communications 12 (1) (2021)
Karolin Walter, Eva Rodriguez-Aznar, Monica S Ventura Ferreira, Pierre-Olivier Frappart, Tabea Dittrich, Kanishka Tiwary, Sabine Meessen, Laura Lerma, Nora Daiss, Lucas-Alexander Schulte, Zeynab Najafova, Frank Arnold, Valentyn Usachov, Ninel Azoitei, Mert Erkan, Andre Lechel, Tim Henrik Brümmendorf, Thomas Seufferlein, Alexander Kleger, Enrique Tabarés, Cagatay Gunes, Steven A Johnsen, Fabian Beier, Bruno Sainz, Patrick Christian Hermann
Telomerase and Pluripotency Factors Jointly Regulate Stemness in Pancreatic Cancer Stem Cells. Cancers 13 (13) (2021)
Ana Patricia Kutschat, Feda H Hamdan, Xin Wang, Alexander Q Wixom, Zeynab Najafova, Christine S Gibhardt, Waltraut Kopp, Jochen Gaedcke, Philipp Ströbel, Volker Ellenrieder, Ivan Bogeski, Elisabeth Hessmann, Steven A Johnsen
STIM1 Mediates Calcium-Dependent Epigenetic Reprogramming in Pancreatic Cancer. Cancer research 81 (11) (2021)
Kristin Koerdel, Melanie Spitzner, Thomas Meyer, Niklas Engels, Florian Krause, Jochen Gaedcke, Lena-Christin Conradi, Martin Haubrock, Tim Beißbarth, Andreas Leha, Steven A Johnsen, B Michael Ghadimi, Stefan Rose-John, Marian Grade, Jürgen Wienands
NOTCH Activation via gp130/STAT3 Signaling Confers Resistance to Chemoradiotherapy. Cancers 13 (3) (2021)
Robyn Laura Kosinsky, Dominik Saul, Christoph Ammer-Herrmenau, William A Faubion, Albrecht Neesse, Steven A Johnsen
USP22 Suppresses SPARC Expression in Acute Colitis and Inflammation-Associated Colorectal Cancer. Cancers 13 (8) (2021)
Robyn Laura Kosinsky, Maria Zerche, Ana Patricia Kutschat, Asha Nair, Zhenqing Ye, Dominik Saul, Maximilian von Heesen, Jessica J Friton, Ana Carolina Schwarzer, Nadia Paglilla, Shehzad Z Sheikh, Florian Wegwitz, Zhifu Sun, Michael Ghadimi, Rodney D Newberry, R Balfour Sartor, William A Faubion, Steven A Johnsen
RNF20 and RNF40 regulate vitamin D receptor-dependent signaling in inflammatory bowel disease. Cell death and differentiation 28 (11) (2021)
Xin Wang, Ana P Kutschat, Moyuru Yamada, Evangelos Prokakis, Patricia Böttcher, Koji Tanaka, Yuichiro Doki, Feda H Hamdan, Steven A Johnsen
Bromodomain protein BRDT directs ΔNp63 function and super-enhancer activity in a subset of esophageal squamous cell carcinomas. Cell death and differentiation 28 (7) (2021)
Evangelos Prokakis, Anna Dyas, Regina Grün, Sonja Fritzsche, Upasana Bedi, Zahra B Kazerouni, Robyn Laura Kosinsky, Steven A Johnsen, Florian Wegwitz
USP22 promotes HER2-driven mammary carcinoma aggressiveness by suppressing the unfolded protein response. Oncogene 40 (23) (2021)
Ana Patricia Kutschat, Steven A Johnsen, Feda H Hamdan
Store-Operated Calcium Entry: Shaping the Transcriptional and Epigenetic Landscape in Pancreatic Cancer. Cells 10 (5) (2021)
Wanhua Xie, Michaela Miehe, Sandra Laufer, Steven A Johnsen
The H2B ubiquitin-protein ligase RNF40 is required for somatic cell reprogramming. Cell death & disease 11 (4) (2020)
Maria Wiese, Feda H Hamdan, Klaudia Kubiak, Christopher Diederichs, Gerrit H Gielen, Gunther Nussbaumer, Angel Montero Carcaboso, Esther Hulleman, Steven A Johnsen, Christof M Kramm
Combined treatment with CBP and BET inhibitors reverses inadvertent activation of detrimental super enhancer programs in DIPG cells. Cell death & disease 11 (8) (2020)
Zeynab Najafova, Peng Liu, Florian Wegwitz, Mubashir Ahmad, Liezel Tamon, Robyn Laura Kosinsky, Wanhua Xie, Steven A Johnsen, Jan P Tuckermann
RNF40 exerts stage-dependent functions in differentiating osteoblasts and is essential for bone cell crosstalk. Cell death and differentiation 28 (2) (2020)
Shilpa Patil, Benjamin Steuber, Waltraut Kopp, Vijayalakshmi Kari, Laura Urbach, Xin Wang, Stefan Küffer, Hanibal Bohnenberger, Dimitra Spyropoulou, Zhe Zhang, Lennart Versemann, Mark Sebastian Bösherz, Marius Brunner, Jochen Gaedcke, Philipp Ströbel, Jin-San Zhang, Albrecht Neesse, Volker Ellenrieder, Shiv K Singh, Steven A Johnsen, Elisabeth Hessmann
EZH2 Regulates Pancreatic Cancer Subtype Identity and Tumor Progression via Transcriptional Repression of GATA6. Cancer research 80 (21) (2020)
Florian Wegwitz, Evangelos Prokakis, Anastasija Pejkovska, Robyn Laura Kosinsky, Markus Glatzel, Klaus Pantel, Harriett Wikman, Steven A Johnsen
The histone H2B ubiquitin ligase RNF40 is required for HER2-driven mammary tumorigenesis. Cell death & disease 11 (10) (2020)
Malek Kammoun, Jerome Piquereau, Lydie Nadal-Desbarats, Sandra Même, Maud Beuvin, Gisèle Bonne, Vladimir Veksler, Yann Le Fur, Philippe Pouletaut, William Même, Frederic Szeremeta, Jean-Marc Constans, Elizabeth S Bruinsma, Molly H Nelson Holte, Zeynab Najafova, Steven A Johnsen, Malayannan Subramaniam, John R Hawse, Sabine F Bensamoun
Novel role of Tieg1 in muscle metabolism and mitochondrial oxidative capacities. Acta physiologica (Oxford, England) 228 (3) (2019)
Vijayalakshmi Kari, Sanjay Kumar Raul, Jana Maria Henck, Julia Kitz, Frank Kramer, Robyn Laura Kosinsky, Nadine Übelmesser, Wael Yassin Mansour, Jessica Eggert, Melanie Spitzner, Zeynab Najafova, Holger Bastians, Marian Grade, Jochen Gaedcke, Florian Wegwitz, Steven A Johnsen
The histone methyltransferase DOT1L is required for proper DNA damage response, DNA repair, and modulates chemotherapy responsiveness. Clinical epigenetics 11 (1) (2019)
Madhobi Sen, Xin Wang, Feda H Hamdan, Jacobe Rapp, Jessica Eggert, Robyn Laura Kosinsky, Florian Wegwitz, Ana Patricia Kutschat, Fereshteh S Younesi, Jochen Gaedcke, Marian Grade, Elisabeth Hessmann, Argyris Papantonis, Philipp Strӧbel, Steven A Johnsen
ARID1A facilitates KRAS signaling-regulated enhancer activity in an AP1-dependent manner in colorectal cancer cells. Clinical epigenetics 11 (1) (2019)
Robyn Laura Kosinsky, Marlena Helms, Maria Zerche, Luisa Wohn, Anna Dyas, Evangelos Prokakis, Zahra Basir Kazerouni, Upasana Bedi, Florian Wegwitz, Steven A Johnsen
USP22-dependent HSP90AB1 expression promotes resistance to HSP90 inhibition in mammary and colorectal cancer. Cell death & disease 10 (12) (2019)
Robyn Laura Kosinsky, Maria Zerche, Dominik Saul, Xin Wang, Luisa Wohn, Florian Wegwitz, Yvonne Begus-Nahrmann, Steven A Johnsen
USP22 exerts tumor-suppressive functions in colorectal cancer by decreasing mTOR activity. Cell death and differentiation 27 (4) (2019)
Hannah Flebbe, Feda H Hamdan, Vijayalakshmi Kari, Julia Kitz, Jochen Gaedcke, B Michael Ghadimi, Steven A Johnsen, Marian Grade
Epigenome Mapping Identifies Tumor-Specific Gene Expression in Primary Rectal Cancer. Cancers 11 (8) (2019)
Feda H Hamdan, Steven A Johnsen
Perturbing Enhancer Activity in Cancer Therapy. Cancers 11 (5) (2019)
Feda H Hamdan, Steven A Johnsen
DeltaNp63-dependent super enhancers define molecular identity in pancreatic cancer by an interconnected transcription factor network. Proceedings of the National Academy of Sciences of the United States of America 115 (52) (2018)
Feda H Hamdan, Steven A Johnsen
Super enhancers - new analyses and perspectives on the low hanging fruit. Transcription 9 (2) (2017)
Vijayalakshmi Kari, Wael Yassin Mansour, Sanjay Kumar Raul, Simon J Baumgart, Andreas Mund, Marian Grade, Hüseyin Sirma, Ronald Simon, Hans Will, Matthias Dobbelstein, Ekkehard Dikomey, Steven A Johnsen
Loss of CHD1 causes DNA repair defects and enhances prostate cancer therapeutic responsiveness. EMBO reports 17 (11) (2016)

Steven A Johnsen.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Steven A Johnsen