Alvaro Sanchez-Martinez

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 20

Top Venues

eLife

Life science alliance

Science translational medicine

Nature communications

MRC Mitochondrial Biology Unit

Universidad Autónoma de Madrid (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

MRC Mitochondrial Biology Unit Nov 02 2015

United Kingdom

Investigator Scientist :: MBU, University of Cambridge

University of Sheffield May 17 2010 - Oct 31 2015

United Kingdom

Postdoctoral Research associate :: Biomedical Science

Universidad Autónoma de Madrid Oct 21 2009 - Apr 20 2010

Spain

Postdoctoral Research associate :: Biochemistry

Education History

Universidad Autónoma de Madrid Oct 04 2003 - Oct 20 2009

Spain

PHD :: Biochemistry

Publications

Wing Hei Au, Leonor Miller-Fleming, Alvaro Sanchez-Martinez, James Ak Lee, Madeleine J Twyning, Hiran A Prag, Laura Raik, Scott P Allen, Pamela J Shaw, Laura Ferraiuolo, Heather Mortiboys, Alexander J Whitworth
Activation of the Keap1/Nrf2 pathway suppresses mitochondrial dysfunction, oxidative stress, and motor phenotypes in C9orf72 ALS/FTD models. Life science alliance 7 (9) (2024)
Wing Hei Au, Leonor Miller-Fleming, Alvaro Sanchez-Martinez, James Ak Lee, Madeleine J Twyning, Hiran A Prag, Laura Raik, Scott P Allen, Pamela J Shaw, Laura Ferraiuolo, Heather Mortiboys, Alexander J Whitworth
Activation of the Keap1/Nrf2 pathway suppresses mitochondrial dysfunction, oxidative stress, and motor phenotypes in C9orf72 ALS/FTD models. Life science alliance 7 (9) (2024)
Wing Hei Au, Leonor Miller-Fleming, Alvaro Sanchez-Martinez, James Ak Lee, Madeleine J Twyning, Hiran A Prag, Laura Raik, Scott P Allen, Pamela J Shaw, Laura Ferraiuolo, Heather Mortiboys, Alexander J Whitworth
Activation of the Keap1/Nrf2 pathway suppresses mitochondrial dysfunction, oxidative stress, and motor phenotypes in C9orf72 ALS/FTD models. Life science alliance 7 (9) (2024)
Ahmed-Noor A Agip, Injae Chung, Alvaro Sanchez-Martinez, Alexander J Whitworth, Judy Hirst
Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster . eLife 12 (2023)
Lydia M Castelli, Ya-Hui Lin, Alvaro Sanchez-Martinez, Aytaç Gül, Kamallia Mohd Imran, Adrian Higginbottom, Santosh Kumar Upadhyay, Nóra M Márkus, Raquel R Martins, Johnathan Cooper-Knock, Claire Montmasson, Rebecca Cohen, Amy Walton, Claudia S Bauer, Kurt J De Vos, Richard J Mead, Mimoun Azzouz, Cyril Dominguez, Laura Ferraiuolo, Dame Pamela J Shaw, Alexander J Whitworth, Guillaume M Hautbergue
A cell-penetrant peptide blocking C9ORF72 -repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins. Science translational medicine 15 (685) (2023)
Lydia M Castelli, Ya-Hui Lin, Alvaro Sanchez-Martinez, Aytaç Gül, Kamallia Mohd Imran, Adrian Higginbottom, Santosh Kumar Upadhyay, Nóra M Márkus, Raquel R Martins, Johnathan Cooper-Knock, Claire Montmasson, Rebecca Cohen, Amy Walton, Claudia S Bauer, Kurt J De Vos, Richard J Mead, Mimoun Azzouz, Cyril Dominguez, Laura Ferraiuolo, Dame Pamela J Shaw, Alexander J Whitworth, Guillaume M Hautbergue
A cell-penetrant peptide blocking C9ORF72 -repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins. Science translational medicine 15 (685) (2023)
Ahmed-Noor A Agip, Injae Chung, Alvaro Sanchez-Martinez, Alexander J Whitworth, Judy Hirst
Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster . eLife 12 (2023)
Ahmed-Noor A Agip, Injae Chung, Alvaro Sanchez-Martinez, Alexander J Whitworth, Judy Hirst
Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster . eLife 12 (2023)
Ahmed-Noor A Agip, Injae Chung, Alvaro Sanchez-Martinez, Alexander J Whitworth, Judy Hirst
Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster . eLife 12 (2023)
Alvaro Sanchez-Martinez, Aitor Martinez, Alexander J Whitworth
FBXO7/ntc and USP30 antagonistically set the ubiquitination threshold for basal mitophagy and provide a target for Pink1 phosphorylation in vivo. PLoS biology 21 (8) (2023)
Ahmed-Noor A Agip, Injae Chung, Alvaro Sanchez-Martinez, Alexander J Whitworth, Judy Hirst
Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster . eLife 12 (2023)
Ahmed-Noor A Agip, Injae Chung, Alvaro Sanchez-Martinez, Alexander J Whitworth, Judy Hirst
Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster . eLife 12 (2023)
Lydia M Castelli, Ya-Hui Lin, Alvaro Sanchez-Martinez, Aytaç Gül, Kamallia Mohd Imran, Adrian Higginbottom, Santosh Kumar Upadhyay, Nóra M Márkus, Raquel R Martins, Johnathan Cooper-Knock, Claire Montmasson, Rebecca Cohen, Amy Walton, Claudia S Bauer, Kurt J De Vos, Richard J Mead, Mimoun Azzouz, Cyril Dominguez, Laura Ferraiuolo, Dame Pamela J Shaw, Alexander J Whitworth, Guillaume M Hautbergue
A cell-penetrant peptide blocking C9ORF72 -repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins. Science translational medicine 15 (685) (2023)
Maeve Long, Alvaro Sanchez-Martinez, Marianna Longo, Fumi Suomi, Hans Stenlund, Annika I Johansson, Homa Ehsan, Veijo T Salo, Lambert Montava-Garriga, Seyedehshima Naddafi, Elina Ikonen, Ian G Ganley, Alexander J Whitworth, Thomas G McWilliams
DGAT1 activity synchronises with mitophagy to protect cells from metabolic rewiring by iron depletion. The EMBO journal 41 (10) (2022)
Joanne L Usher, Alvaro Sanchez-Martinez, Ana Terriente-Felix, Po-Lin Chen, Juliette J Lee, Chun-Hong Chen, Alexander J Whitworth
Parkin drives pS65-Ub turnover independently of canonical autophagy in Drosophila. EMBO reports 23 (12) (2022)
Sophia von Stockum, Alvaro Sanchez-Martinez, Samantha Corrà, Joy Chakraborty, Elena Marchesan, Locatello Lisa, Caterina Da Rè, Paola Cusumano, Federico Caicci, Vanni Ferrari, Rodolfo Costa, Luigi Bubacco, Maria Berica Rasotto, Ildiko Szabo, Alexander J Whitworth, Luca Scorrano, Ziviani Elena
Inhibition of the deubiquitinase USP8 corrects a Drosophila PINK1 model of mitochondria dysfunction. Life science alliance 2 (2) (2019)
Simonetta Andreazza, Colby L Samstag, Alvaro Sanchez-Martinez, Erika Fernández-Vizarra, Aurora Gomez-Duran, Juliette J Lee, Roberta Tufi, Michael J Hipp, Elizabeth K Schmidt, Thomas J Nicholls, Payam A Gammage, Patrick F Chinnery, Michal Minczuk, Leo J Pallanck, Scott R Kennedy, Alexander J Whitworth
Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila. Nature communications 10 (1) (2019)
Juliette J Lee, Alvaro Sanchez-Martinez, Aitor Martinez Zarate, Cristiane Benincá, Ugo Mayor, Michael J Clague, Alexander J Whitworth
Basal mitophagy is widespread in Drosophila but minimally affected by loss of Pink1 or parkin. The Journal of cell biology 217 (5) (2018)
Domenica Lovero, Luca Giordano, René Massimiliano Marsano, Alvaro Sanchez-Martinez, Hadi Boukhatmi, Maik Drechsler, Marta Oliva, Alexander J Whitworth, Damiano Porcelli, Corrado Caggese
Characterization of Drosophila ATPsynC mutants as a new model of mitochondrial ATP synthase disorders. PloS one 13 (8) (2018)
Guillaume M Hautbergue, Lydia M Castelli, Laura Ferraiuolo, Alvaro Sanchez-Martinez, Johnathan Cooper-Knock, Adrian Higginbottom, Ya-Hui Lin, Claudia S Bauer, Jennifer E Dodd, Monika A Myszczynska, Sarah M Alam, Pierre Garneret, Jayanth S Chandran, Evangelia Karyka, Matthew J Stopford, Emma F Smith, Janine Kirby, Kathrin C Meyer, Brian K Kaspar, Adrian M Isaacs, Sherif F El-Khamisy, Kurt J De Vos, Ke Ning, Mimoun Azzouz, Alexander J Whitworth, Pamela J Shaw
SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits. Nature communications 8 (2017)

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Publication Activity (10 Years)

Top Topics

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Alvaro Sanchez-Martinez