Guillaume M Hautbergue (Guillaume Hautbergue)

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 15

Top Topics

Protein Protein

Machine Learning

Genome Wide Association Study

Top Venues

Science translational medicine

Life science alliance

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Lydia M Castelli, Ya-Hui Lin, Alvaro Sanchez-Martinez, Aytaç Gül, Kamallia Mohd Imran, Adrian Higginbottom, Santosh Kumar Upadhyay, Nóra M Márkus, Raquel R Martins, Johnathan Cooper-Knock, Claire Montmasson, Rebecca Cohen, Amy Walton, Claudia S Bauer, Kurt J De Vos, Richard J Mead, Mimoun Azzouz, Cyril Dominguez, Laura Ferraiuolo, Dame Pamela J Shaw, Alexander J Whitworth, Guillaume M Hautbergue
A cell-penetrant peptide blocking C9ORF72 -repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins. Science translational medicine 15 (685) (2023)
Lydia M Castelli, Ya-Hui Lin, Alvaro Sanchez-Martinez, Aytaç Gül, Kamallia Mohd Imran, Adrian Higginbottom, Santosh Kumar Upadhyay, Nóra M Márkus, Raquel R Martins, Johnathan Cooper-Knock, Claire Montmasson, Rebecca Cohen, Amy Walton, Claudia S Bauer, Kurt J De Vos, Richard J Mead, Mimoun Azzouz, Cyril Dominguez, Laura Ferraiuolo, Dame Pamela J Shaw, Alexander J Whitworth, Guillaume M Hautbergue
A cell-penetrant peptide blocking C9ORF72 -repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins. Science translational medicine 15 (685) (2023)
Simeon R Mihaylov, Lydia M Castelli, Ya-Hui Lin, Aytac Gül, Nikita Soni, Christopher Hastings, Helen R Flynn, Oana Păun, Mark J Dickman, Ambrosius P Snijders, Robert Goldstone, Oliver Bandmann, Tatyana A Shelkovnikova, Heather Mortiboys, Sila K Ultanir, Guillaume M Hautbergue
The master energy homeostasis regulator PGC-1α exhibits an mRNA nuclear export function. Nature communications 14 (1) (2023)
Lydia M Castelli, Ya-Hui Lin, Alvaro Sanchez-Martinez, Aytaç Gül, Kamallia Mohd Imran, Adrian Higginbottom, Santosh Kumar Upadhyay, Nóra M Márkus, Raquel R Martins, Johnathan Cooper-Knock, Claire Montmasson, Rebecca Cohen, Amy Walton, Claudia S Bauer, Kurt J De Vos, Richard J Mead, Mimoun Azzouz, Cyril Dominguez, Laura Ferraiuolo, Dame Pamela J Shaw, Alexander J Whitworth, Guillaume M Hautbergue
A cell-penetrant peptide blocking C9ORF72 -repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins. Science translational medicine 15 (685) (2023)
Evangelia Karyka, Nelly Berrueta Ramirez, Christopher P Webster, Paolo M Marchi, Emily J Graves, Vinay K Godena, Lara Marrone, Anushka Bhargava, Swagat Ray, Ke Ning, Hannah Crane, Guillaume M Hautbergue, Sherif F El-Khamisy, Mimoun Azzouz
SMN-deficient cells exhibit increased ribosomal DNA damage. Life science alliance 5 (8) (2022)
Pamela J Shaw, Valerie Odon, Calum Harvey, Mark O Collins, Andrew Peden, John Franklin, Emily Graves, Jack Ng Marshall, Cleide Dos Santos Souza, Sai Zhang, Lydia Castelli, Guillaume M Hautbergue, Mimoun Azzouz, David Gordon, Nevan J Krogan, Laura Ferraiuolo, Michael P Snyder, Pamela J Shaw, Jan Rehwinkel, Johnathan Cooper-Knock
Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication. Life science alliance 6 (1) (2022)
Paolo M Marchi, Lara Marrone, Laurent Brasseur, Audrey Coens, Christopher P Webster, Luc Bousset, Marco Destro, Emma F Smith, Christa G Walther, Victor Alfred, Raffaele Marroccella, Emily J Graves, Darren Robinson, Allan C Shaw, Lai Mei Wan, Andrew J Grierson, Stephen J Ebbens, Kurt J De Vos, Guillaume M Hautbergue, Laura Ferraiuolo, Ronald Melki, Mimoun Azzouz
C9ORF72 -derived poly-GA DPRs undergo endocytic uptake in iAstrocytes and spread to motor neurons. Life science alliance 5 (9) (2022)
Lydia M Castelli, Luisa Cutillo, Cleide Dos Santos Souza, Alvaro Sanchez-Martinez, Ilaria Granata, Ya-Hui Lin, Monika A Myszczynska, Paul R Heath, Matthew R Livesey, Ke Ning, Mimoun Azzouz, Pamela J Shaw, Mario R Guarracino, Alexander J Whitworth, Laura Ferraiuolo, Marta Milo, Guillaume M Hautbergue
SRSF1-dependent inhibition of C9ORF72-repeat RNA nuclear export: genome-wide mechanisms for neuroprotection in amyotrophic lateral sclerosis. Molecular neurodegeneration 16 (1) (2021)
Monika A Myszczynska, Poojitha N Ojamies, Alix M B Lacoste, Daniel Neil, Amir Saffari, Richard J Mead, Guillaume M Hautbergue, Joanna D Holbrook, Laura Ferraiuolo
Applications of machine learning to diagnosis and treatment of neurodegenerative diseases. Nature reviews. Neurology 16 (8) (2020)
Aleksander Rust, Sajid Shah, Guillaume M Hautbergue, Bazbek Davletov
Burkholderia Lethal Factor 1, a Novel Anti-Cancer Toxin, Demonstrates Selective Cytotoxicity in MYCN-Amplified Neuroblastoma Cells. Toxins 10 (7) (2018)
Callum Walker, Saul Herranz-Martin, Evangelia Karyka, Chunyan Liao, Katherine Lewis, Waheba Elsayed, Vera Lukashchuk, Shih-Chieh Chiang, Swagat Ray, Padraig J Mulcahy, Mateusz Jurga, Ioannis Tsagakis, Tommaso Iannitti, Jayanth Chandran, Ian Coldicott, Kurt J De Vos, Mohamed K Hassan, Adrian Higginbottom, Pamela J Shaw, Guillaume M Hautbergue, Mimoun Azzouz, Sherif F El-Khamisy
C9orf72 expansion disrupts ATM-mediated chromosomal break repair. Nature neuroscience 20 (9) (2017)
Jayanth S Chandran, Paul S Sharp, Evangelia Karyka, João Miguel da Conceição Aves-Cruzeiro, Ian Coldicott, Lydia Castelli, Guillaume M Hautbergue, Mark O Collins, Mimoun Azzouz
Site Specific Modification of Adeno-Associated Virus Enables Both Fluorescent Imaging of Viral Particles and Characterization of the Capsid Interactome. Scientific reports 7 (1) (2017)
Guillaume M Hautbergue, Lydia M Castelli, Laura Ferraiuolo, Alvaro Sanchez-Martinez, Johnathan Cooper-Knock, Adrian Higginbottom, Ya-Hui Lin, Claudia S Bauer, Jennifer E Dodd, Monika A Myszczynska, Sarah M Alam, Pierre Garneret, Jayanth S Chandran, Evangelia Karyka, Matthew J Stopford, Emma F Smith, Janine Kirby, Kathrin C Meyer, Brian K Kaspar, Adrian M Isaacs, Sherif F El-Khamisy, Kurt J De Vos, Ke Ning, Mimoun Azzouz, Alexander J Whitworth, Pamela J Shaw
SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits. Nature communications 8 (2017)
Aleksander Rust, Lynda J Partridge, Bazbek Davletov, Guillaume M Hautbergue
The Use of Plant-Derived Ribosome Inactivating Proteins in Immunotoxin Development: Past, Present and Future Generations. Toxins 9 (11) (2017)
Christopher P Webster, Emma F Smith, Claudia S Bauer, Annekathrin Moller, Guillaume M Hautbergue, Laura Ferraiuolo, Monika A Myszczynska, Adrian Higginbottom, Matthew J Walsh, Alexander J Whitworth, Brian K Kaspar, Kathrin Meyer, Pamela J Shaw, Andrew J Grierson, Kurt J De Vos
The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy. The EMBO journal 35 (15) (2016)