Johnathan Cooper-Knock (J Cooper-Knock, Jonathan Cooper-Knock)

Scopus Author ID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 24

Top Topics

Amyotrophic Lateral Sclerosis

Dna Methylation

Top Venues

Journal of the American Heart Association

Science translational medicine

Journal of neurology, neurosurgery, and psychiatry

International journal of molecular sciences

This page only lists publications with an associated author ORCID identifier.

Publications

Elham Alhathli, Thomas Henry Julian, Zain Ul Abideen Girach, Alfred Arthur Roger Thompson, Christopher J Rhodes, Stefan Gräf, Niamh Errington, Martin R Wilkins, Allan Lawrie, Dennis Wang, Johnathan Cooper-Knock
Mendelian Randomization Study With Clinical Follow-Up Links Metabolites to Risk and Severity of Pulmonary Arterial Hypertension. Journal of the American Heart Association 13 (6) (2024)
Elham Alhathli, Thomas Henry Julian, Zain Ul Abideen Girach, Alfred Arthur Roger Thompson, Christopher J Rhodes, Stefan Gräf, Niamh Errington, Martin R Wilkins, Allan Lawrie, Dennis Wang, Johnathan Cooper-Knock
Mendelian Randomization Study With Clinical Follow-Up Links Metabolites to Risk and Severity of Pulmonary Arterial Hypertension. Journal of the American Heart Association 13 (6) (2024)
Elham Alhathli, Thomas Henry Julian, Zain Ul Abideen Girach, Alfred Arthur Roger Thompson, Christopher J Rhodes, Stefan Gräf, Niamh Errington, Martin R Wilkins, Allan Lawrie, Dennis Wang, Johnathan Cooper-Knock
Mendelian Randomization Study With Clinical Follow-Up Links Metabolites to Risk and Severity of Pulmonary Arterial Hypertension. Journal of the American Heart Association 13 (6) (2024)
Marcel Weinreich, Harry McDonough, Nancy Sarah Yacovzada, Iddo Magen, Yahel Cohen, Calum Harvey, Sarah Gornall, Sarah Boddy, James J P Alix, Nima Mohseni, Julian M Kurz, Kevin P Kenna, Sai Zhang, Alfredo Iacoangeli, Ahmad Al Khleifat, Michael Paul Snyder, Esther V Hobson, Ammar Al-Chalabi, Eran Hornstein, Eran Elhaik, Dame Pamela J Shaw, Christopher J McDermott, Johnathan Cooper-Knock
predicTTE: An accessible and optimal tool for time-to-event prediction in neurological diseases. bioRxiv : the preprint server for biology (2024)
Elham Alhathli, Thomas Henry Julian, Zain Ul Abideen Girach, Alfred Arthur Roger Thompson, Christopher J Rhodes, Stefan Gräf, Niamh Errington, Martin R Wilkins, Allan Lawrie, Dennis Wang, Johnathan Cooper-Knock
Mendelian Randomization Study With Clinical Follow-Up Links Metabolites to Risk and Severity of Pulmonary Arterial Hypertension. Journal of the American Heart Association 13 (6) (2024)
Marcel Weinreich, Harry McDonough, Nancy Sarah Yacovzada, Iddo Magen, Yahel Cohen, Calum Harvey, Sarah Gornall, Sarah Boddy, James J P Alix, Nima Mohseni, Julian M Kurz, Kevin P Kenna, Sai Zhang, Alfredo Iacoangeli, Ahmad Al Khleifat, Michael Paul Snyder, Esther V Hobson, Ammar Al-Chalabi, Eran Hornstein, Eran Elhaik, Dame Pamela J Shaw, Christopher J McDermott, Johnathan Cooper-Knock
predicTTE: An accessible and optimal tool for time-to-event prediction in neurological diseases. bioRxiv : the preprint server for biology (2024)
Elham Alhathli, Thomas Henry Julian, Zain Ul Abideen Girach, Alfred Arthur Roger Thompson, Christopher J Rhodes, Stefan Gräf, Niamh Errington, Martin R Wilkins, Allan Lawrie, Dennis Wang, Johnathan Cooper-Knock
Mendelian Randomization Study With Clinical Follow-Up Links Metabolites to Risk and Severity of Pulmonary Arterial Hypertension. Journal of the American Heart Association (2024)
Elham Alhathli, Thomas Henry Julian, Zain Ul Abideen Girach, Alfred Arthur Roger Thompson, Christopher J Rhodes, Stefan Gräf, Niamh Errington, Martin R Wilkins, Allan Lawrie, Dennis Wang, Johnathan Cooper-Knock
Mendelian Randomization Study With Clinical Follow-Up Links Metabolites to Risk and Severity of Pulmonary Arterial Hypertension. Journal of the American Heart Association 13 (6) (2024)
Lydia M Castelli, Ya-Hui Lin, Alvaro Sanchez-Martinez, Aytaç Gül, Kamallia Mohd Imran, Adrian Higginbottom, Santosh Kumar Upadhyay, Nóra M Márkus, Raquel R Martins, Johnathan Cooper-Knock, Claire Montmasson, Rebecca Cohen, Amy Walton, Claudia S Bauer, Kurt J De Vos, Richard J Mead, Mimoun Azzouz, Cyril Dominguez, Laura Ferraiuolo, Dame Pamela J Shaw, Alexander J Whitworth, Guillaume M Hautbergue
A cell-penetrant peptide blocking C9ORF72 -repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins. Science translational medicine 15 (685) (2023)
Lydia M Castelli, Ya-Hui Lin, Alvaro Sanchez-Martinez, Aytaç Gül, Kamallia Mohd Imran, Adrian Higginbottom, Santosh Kumar Upadhyay, Nóra M Márkus, Raquel R Martins, Johnathan Cooper-Knock, Claire Montmasson, Rebecca Cohen, Amy Walton, Claudia S Bauer, Kurt J De Vos, Richard J Mead, Mimoun Azzouz, Cyril Dominguez, Laura Ferraiuolo, Dame Pamela J Shaw, Alexander J Whitworth, Guillaume M Hautbergue
A cell-penetrant peptide blocking C9ORF72 -repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins. Science translational medicine 15 (685) (2023)
Laura R Chapman, Johnathan Cooper-Knock, Dame Pamela J Shaw
Physical activity as an exogenous risk factor for amyotrophic lateral sclerosis: a review of the evidence. Brain : a journal of neurology (2023)
Lydia M Castelli, Ya-Hui Lin, Alvaro Sanchez-Martinez, Aytaç Gül, Kamallia Mohd Imran, Adrian Higginbottom, Santosh Kumar Upadhyay, Nóra M Márkus, Raquel R Martins, Johnathan Cooper-Knock, Claire Montmasson, Rebecca Cohen, Amy Walton, Claudia S Bauer, Kurt J De Vos, Richard J Mead, Mimoun Azzouz, Cyril Dominguez, Laura Ferraiuolo, Dame Pamela J Shaw, Alexander J Whitworth, Guillaume M Hautbergue
A cell-penetrant peptide blocking C9ORF72 -repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins. Science translational medicine 15 (685) (2023)
Chen Eitan, Aviad Siany, Elad Barkan, Tsviya Olender, Kristel R van Eijk, Matthieu Moisse, Sali M K Farhan, Yehuda M Danino, Eran Yanowski, Hagai Marmor-Kollet, Natalia Rivkin, Nancy Sarah Yacovzada, Shu-Ting Hung, Johnathan Cooper-Knock, Chien-Hsiung Yu, Cynthia Louis, Seth L Masters, Kevin P Kenna, Rick A A van der Spek, William Sproviero, Ahmad Al Khleifat, Alfredo Iacoangeli, Aleksey Shatunov, Ashley R Jones, Yael Elbaz-Alon, Yahel Cohen, Elik Chapnik, Daphna Rothschild, Omer Weissbrod, Gilad Beck, Elena Ainbinder, Shifra Ben-Dor, Sebastian Werneburg, Dorothy P Schafer, Robert H Brown, Pamela J Shaw, Philip Van Damme, Leonard H van den Berg, Hemali Phatnani, Eran Segal, Justin K Ichida, Ammar Al Chalabi, Jan Herman Veldink, null null, null null, Eran Hornstein
Whole-genome sequencing reveals that variants in the Interleukin 18 Receptor Accessory Protein 3'UTR protect against ALS. Nature neuroscience 25 (4) (2022)
Paul J Hop, Ramona A J Zwamborn, Eilis J Hannon, Gemma L Shireby, Marta F Nabais, Emma M Walker, Wouter Van Rheenen, Joke J F A van Vugt, Annelot M Dekker, Henk-Jan Westeneng, Gijs H P Tazelaar, Kristel R van Eijk, Matthieu Moisse, Denis Baird, Ahmad Al Khleifat, Alfredo Iacoangeli, Nicola Ticozzi, Antonia Ratti, Johnathan Cooper-Knock, Karen E Morrison, Dame Pamela J Shaw, Ayse Nazli Basak, Adriano Chio, Andrea Calvo, Cristina Moglia, Antonio Canosa, Maura Brunetti, Maurizio Grassano, Marc Gotkine, Yossef Lerner, Michal Zabari, Patrick Vourc'h, Philippe Corcia, Philippe Couratier, Jesus S Mora, Teresa Salas, Patrick Dion, Jay P Ross, Robert David Henderson, Susan Mathers, Pamela A McCombe, Merrilee Needham, Garth Nicholson, Dominic B Rowe, Roger Pamphlett, Karen A Mather, Perminder Singh Sachdev, Sarah Furlong, Fleur C Garton, Anjali K Henders, Tian Lin, Shyuan T Ngo, Frederik J Steyn, Leanne Wallace, Kelly Louise Williams, null null, null null, Miguel Mitne Neto, Ruben J Cauchi, Ian P Blair, Matthew C Kiernan, Vivian Drory, Monica Povedano, Mamede de Carvalho, Susana Pinto, Markus Weber, Guy A Rouleau, Vincenzo Silani, John E Landers, Christopher E Shaw, Peter Munch Andersen, Allan F McRae, Michael A van Es, R Jeroen Pasterkamp, Naomi R Wray, Russell Lewis McLaughlin, Orla Hardiman, Kevin P Kenna, Ellen A Tsai, Heiko Runz, Ammar Al Chalabi, Leonard H van den Berg, Philip Van Damme, Jonathan S Mill, Jan Herman Veldink
Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS. Science translational medicine 14 (633) (2022)
Johnathan Cooper-Knock, Thomas H Julian, Emily Feneberg, J Robin Highley, Maurice Sidra, Martin R Turner, Kevin Talbot, Olaf Ansorge, Scott P Allen, Tobias Moll, Tatyana Shelkovnikova, Lydia Castelli, Guillaume M Hautbergue, Christopher Hewitt, Janine Kirby, Stephen B Wharton, Richard J Mead, Pamela J Shaw
Atypical TDP-43 protein expression in an ALS pedigree carrying a p.Y374X truncation mutation in TARDBP. Brain pathology (Zurich, Switzerland) (2022)
Sarah Boddy, Mahjabin Islam, Tobias Moll, Julian Kurz, David Burrows, Alexander McGown, Anushka Bhargava, Thomas H Julian, Calum Harvey, Jack Ng Marshall, Benjamin Pc Hall, Scott P Allen, Kevin P Kenna, Eleanor C M Sanderson, Sai Zhang, Tennore Ramesh, Michael P Snyder, Pamela J Shaw, Christopher McDermott, Johnathan Cooper-Knock
Unbiased metabolome screen leads to personalized medicine strategy for amyotrophic lateral sclerosis. Brain communications 4 (2) (2022)
Pamela J Shaw, Valerie Odon, Calum Harvey, Mark O Collins, Andrew Peden, John Franklin, Emily Graves, Jack Ng Marshall, Cleide Dos Santos Souza, Sai Zhang, Lydia Castelli, Guillaume M Hautbergue, Mimoun Azzouz, David Gordon, Nevan J Krogan, Laura Ferraiuolo, Michael P Snyder, Pamela J Shaw, Jan Rehwinkel, Johnathan Cooper-Knock
Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication. Life science alliance 6 (1) (2022)
Johnathan Cooper-Knock
Implications of confirmed de novo pathogenic SOD1 mutations. Journal of neurology, neurosurgery, and psychiatry (2021)
Stephanie R Shepheard, Matthew D Parker, Johnathan Cooper-Knock, Nick S Verber, Lee Tuddenham, Paul Heath, Nick Beauchamp, Elsie Place, Elizabeth S A Sollars, Matthew C Kiernan, Andrea Malaspina, Pietro Fratta, Channa Hewamadduma, Thomas M Jenkins, Christopher J McDermott, Dennis Wang, Janine Kirby, Dame Pamela J Shaw, null null, null null
Value of systematic genetic screening of patients with amyotrophic lateral sclerosis. Journal of neurology, neurosurgery, and psychiatry 92 (5) (2021)
Motaz M Fadul, Paul Roy Heath, Johnathan Cooper-Knock, Julian M Kurz, Hayder A Al-Azzawi, Zarki Ali, Taylor Smith, Fiona E Matthews, Carol Brayne, Stephen B Wharton, Julie E Simpson
Transcriptomic Analysis of Age-Associated Periventricular Lesions Reveals Dysregulation of the Immune Response. International journal of molecular sciences 21 (21) (2020)
Helia Ghahremani Nezhad, John P Franklin, James J P Alix, Tobias Moll, Michael Pattrick, Johnathan Cooper-Knock, Priya Shanmugarajah, Nick J Beauchamp, Marios Hadjivissiliou, David Paling, Christopher J McDermott, Dame Pamela J Shaw, Thomas M Jenkins
Simultaneous ALS and SCA2 associated with an intermediate-length ATXN2 CAG-repeat expansion. Amyotrophic lateral sclerosis & frontotemporal degeneration 22 (7-8) (2020)
B A Ashford, Delphine Boche, Johnathan Cooper-Knock, Paul Roy Heath, Julie E Simpson, J Robin Highley
Review: Microglia in motor neuron disease. Neuropathology and applied neurobiology 47 (2) (2020)
Emily F Goodall, Vicki Leach, Chunfang Wang, Johnathan Cooper-Knock, Paul Roy Heath, David Baker, David R Drew, M Jill Saffrey, Julie E Simpson, Ignacio A Romero, Stephen B Wharton
Age-Associated mRNA and miRNA Expression Changes in the Blood-Brain Barrier. International journal of molecular sciences 20 (12) (2019)
Johnathan Cooper-Knock, Claire Green, Gabriel Altschuler, Wenbin Wei, Joanna J Bury, Paul R Heath, Matthew Wyles, Catherine Gelsthorpe, J Robin Highley, Alejandro Lorente-Pons, Tim Beck, Kathryn Doyle, Karel Otero, Bryan Traynor, Janine Kirby, Pamela J Shaw, Winston Hide
A data-driven approach links microglia to pathology and prognosis in amyotrophic lateral sclerosis. Acta neuropathologica communications 5 (1) (2017)