Andreas Link (A Link)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 37

Top Venues

ChemMedChem

Archiv der Pharmazie

Expert opinion on drug discovery

Molecules (Basel, Switzerland)

Universität Greifswald Mathematisch-Naturwissenschaftliche Fakultät

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Universität Greifswald Mathematisch-Naturwissenschaftliche Fakultät Dec 21 2004

Germany

Full professor :: Institut für Pharmazie

Publications

Abdrrahman Shemsu Surur, Chin Fung Chan, Frieda-Marie Bartz, Iris L K Wong, Van T D Nguyen, Lukas Schulig, Andreas Link, Tak Hang Chan, Larry M C Chow, Patrick J Bednarski
Fexinidazole optimization: enhancing anti-leishmanial profile, metabolic stability and hERG safety. RSC medicinal chemistry (2024)
Daniel Längle, Stephanie Wojtowicz-Piotrowski, Till Priegann, Niklas Keller, Fabian Wesseler, Elena S Reckzeh, Karsten Steffens, Christoph Grathwol, Jana Lemke, Maren Flasshoff, Christian Näther, Anna C Jonson, Andreas Link, Oliver Koch, Gianni M Di Guglielmo, Dennis Schade
Expanding the Chemical Space of Transforming Growth Factor-β (TGFβ) Receptor Type II Degraders with 3,4-Disubstituted Indole Derivatives. ACS pharmacology & translational science 7 (4) (2024)
Felix Potlitz, Gottfried J Palm, Anja Bodtke, Michael Lammers, Dennis Schade, Andreas Link
A Novel C 3/ C 4-Fused Indole Scaffold through Acid-Catalyzed Cascade Reaction. Molecules (Basel, Switzerland) 29 (13) (2024)
Felix Potlitz, Gottfried J Palm, Anja Bodtke, Michael Lammers, Dennis Schade, Andreas Link
A Novel C 3/ C 4-Fused Indole Scaffold through Acid-Catalyzed Cascade Reaction. Molecules (Basel, Switzerland) 29 (13) (2024)
Daniel Längle, Stephanie Wojtowicz-Piotrowski, Till Priegann, Niklas Keller, Fabian Wesseler, Elena S Reckzeh, Karsten Steffens, Christoph Grathwol, Jana Lemke, Maren Flasshoff, Christian Näther, Anna C Jonson, Andreas Link, Oliver Koch, Gianni M Di Guglielmo, Dennis Schade
Expanding the Chemical Space of Transforming Growth Factor-β (TGFβ) Receptor Type II Degraders with 3,4-Disubstituted Indole Derivatives. ACS pharmacology & translational science 7 (4) (2024)
Daniel Längle, Stephanie Wojtowicz-Piotrowski, Till Priegann, Niklas Keller, Fabian Wesseler, Elena S Reckzeh, Karsten Steffens, Christoph Grathwol, Jana Lemke, Maren Flasshoff, Christian Näther, Anna C Jonson, Andreas Link, Oliver Koch, Gianni M Di Guglielmo, Dennis Schade
Expanding the Chemical Space of Transforming Growth Factor-β (TGFβ) Receptor Type II Degraders with 3,4-Disubstituted Indole Derivatives. ACS pharmacology & translational science 7 (4) (2024)
Felix Potlitz, Andreas Link, Lukas Schulig
Advances in the discovery of new chemotypes through ultra-large library docking. Expert opinion on drug discovery 18 (3) (2023)
Felix Potlitz, Andreas Link, Lukas Schulig
Advances in the discovery of new chemotypes through ultra-large library docking. Expert opinion on drug discovery 18 (3) (2023)
Mohsen Ahmadi, Debora Singer, Felix Potlitz, Zahra Nasri, Thomas von Woedtke, Andreas Link, Sander Bekeschus, Kristian Wende
Cold Physical Plasma-Mediated Fenretinide Prodrug Activation Confers Additive Cytotoxicity in Epithelial Cells. Antioxidants (Basel, Switzerland) 12 (6) (2023)
Frieda-Marie Bartz, Kristin Beirow, Konrad Wurm, Daniel Baecker, Andreas Link, Patrick J Bednarski
A graphite furnace-atomic absorption spectrometry-based rubidium efflux assay for screening activators of the K v 7.2/3 channel. Archiv der Pharmazie (2023)
Felix Potlitz, Andreas Link, Lukas Schulig
Advances in the discovery of new chemotypes through ultra-large library docking. Expert opinion on drug discovery (2023)
Felix Potlitz, Andreas Link, Lukas Schulig
Advances in the discovery of new chemotypes through ultra-large library docking. Expert opinion on drug discovery 18 (3) (2023)
Mohsen Ahmadi, Debora Singer, Felix Potlitz, Zahra Nasri, Thomas von Woedtke, Andreas Link, Sander Bekeschus, Kristian Wende
Cold Physical Plasma-Mediated Fenretinide Prodrug Activation Confers Additive Cytotoxicity in Epithelial Cells. Antioxidants (Basel, Switzerland) 12 (6) (2023)
Konrad W Wurm, Frieda-Marie Bartz, Lukas Schulig, Anja Bodtke, Patrick J Bednarski, Andreas Link
Modifications of the Triaminoaryl Metabophore of Flupirtine and Retigabine Aimed at Avoiding Quinone Diimine Formation. ACS omega 7 (9) (2022)
Konrad W Wurm, Frieda-Marie Bartz, Lukas Schulig, Anja Bodtke, Patrick J Bednarski, Andreas Link
Replacing the oxidation-sensitive triaminoaryl chemotype of problematic K V 7 channel openers: Exploration of a nicotinamide scaffold. Archiv der Pharmazie (2022)
Mohsen Ahmadi, Felix Potlitz, Andreas Link, Thomas von Woedtke, Zahra Nasri, Kristian Wende
Flucytosine-based prodrug activation by cold physical plasma. Archiv der Pharmazie 355 (9) (2022)
Lukas Schulig, Norman Geist, Mihaela Delcea, Andreas Link, Martin Kulke
Fundamental Redesign of the TIGER2hs Kernel to Address Severe Parameter Sensitivity. Journal of chemical information and modeling 62 (17) (2022)
Konrad W Wurm, Frieda-Marie Bartz, Lukas Schulig, Anja Bodtke, Patrick J Bednarski, Andreas Link
Carba Analogues of Flupirtine and Retigabine with Improved Oxidation Resistance and Reduced Risk of Quinoid Metabolite Formation. ChemMedChem 17 (16) (2022)
Steven Behnisch-Cornwell, Christoph W Grathwol, Lukas Schulig, Anika Voigt, Daniel Baecker, Andreas Link, Patrick J Bednarski
Correlation Analysis of Protein Expression of 10 HDAC/Sirtuin Isoenzymes with Sensitivities of 23 Anticancer Drugs in 17 Cancer Cell Lines and Potentiation of Drug Activity by Co-Treatment with HDAC Inhibitors. Cancers 14 (1) (2021)
Martin Kulke, Felix Nagel, Lukas Schulig, Norman Geist, Marcel Gabor, Julia Mayerle, Markus M Lerch, Andreas Link, Mihaela Delcea
A Hypothesized Mechanism for Chronic Pancreatitis Caused by the N34S Mutation of Serine Protease Inhibitor Kazal-Type 1 Based on Conformational Studies. Journal of inflammation research 14 (2021)
Lukas Schulig, Piotr Grabarczyk, Norman Geist, Martin Delin, Hannes Forkel, Martin Kulke, Mihaela Delcea, Christian A Schmidt, Andreas Link
Unveiling the N-Terminal Homodimerization of BCL11B by Hybrid Solvent Replica-Exchange Simulations. International journal of molecular sciences 22 (7) (2021)
Qingyun Tang, Christoph W Grathwol, Aşkın S Aslan-Üzel, Shuke Wu, Andreas Link, Ιoannis V Pavlidis, Christoffel P S Badenhorst, Uwe T Bornscheuer
Directed Evolution of a Halide Methyltransferase Enables Biocatalytic Synthesis of Diverse SAM Analogs. Angewandte Chemie (International ed. in English) 60 (3) (2020)
Christoph W Grathwol, Nathalie Wössner, Steven Behnisch-Cornwell, Lukas Schulig, Lin Zhang, Oliver Einsle, Manfred Jung, Andreas Link
Activation of Sirtuin 2 Inhibitors Employing Photoswitchable Geometry and Aqueous Solubility. ChemMedChem 15 (15) (2020)
Sascha Grobe, Christoffel P S Badenhorst, Thomas Bayer, Emil Hamnevik, Shuke Wu, Christoph W Grathwol, Andreas Link, Sven Koban, Henrike Brundiek, Beatrice Großjohann, Uwe T Bornscheuer
Engineering Regioselectivity of a P450 Monooxygenase Enables the Synthesis of Ursodeoxycholic Acid via 7β-Hydroxylation of Lithocholic Acid. Angewandte Chemie (International ed. in English) 60 (2) (2020)
Christian Bock, Abdrrahman S Surur, Kristin Beirow, Markus K Kindermann, Lukas Schulig, Anja Bodtke, Patrick J Bednarski, Andreas Link
Sulfide Analogues of Flupirtine and Retigabine with Nanomolar KV 7.2/KV 7.3 Channel Opening Activity. ChemMedChem 14 (9) (2019)
Abdrrahman S Surur, Kristin Beirow, Christian Bock, Lukas Schulig, Markus K Kindermann, Anja Bodtke, Werner Siegmund, Patrick J Bednarski, Andreas Link
Flupirtine Analogues: Explorative Synthesis and Influence of Chemical Structure on KV7.2/KV7.3 Channel Opening Activity. ChemistryOpen 8 (1) (2019)
Piotr H Małecki, Nicole Rüger, Martin Roatsch, Oxana Krylova, Andreas Link, Manfred Jung, Udo Heinemann, Manfred S Weiss
Structure-Based Screening of Tetrazolylhydrazide Inhibitors versus KDM4 Histone Demethylases. ChemMedChem 14 (21) (2019)
Norman Geist, Martin Kulke, Lukas Schulig, Andreas Link, Walter Langel
Replica-Based Protein Structure Sampling Methods II: Advanced Hybrid Solvent TIGER2hs. The journal of physical chemistry. B 123 (28) (2019)
Christoph W Grathwol, Nathalie Wössner, Sören Swyter, Adam C Smith, Enrico Tapavicza, Robert Klaus Hofstetter, Anja Bodtke, Manfred Jung, Andreas Link
Azologization and repurposing of a hetero-stilbene-based kinase inhibitor: towards the design of photoswitchable sirtuin inhibitors. Beilstein journal of organic chemistry 15 (2019)
Robert Hofstetter, Benedict J Elvers, Felix Potlitz, Andreas Link, Carola Schulzke
Crystal structure of 7,8,15,16,17-penta-thiadi-spiro-[5.2.59.36]hepta-deca-ne. Acta crystallographica. Section E, Crystallographic communications 75 (Pt 6) (2019)
Robert Klaus Hofstetter, Felix Potlitz, Lukas Schulig, Simon Kim, Mahmoud Hasan, Andreas Link
Subcritical Fluid Chromatography at Sub-Ambient Temperatures for the Chiral Resolution of Ketamine Metabolites with Rapid-Onset Antidepressant Effects. Molecules (Basel, Switzerland) 24 (10) (2019)
Christoph W Grathwol, Nicolas Chrysochos, Benedict J Elvers, Andreas Link, Carola Schulzke
Crystal structure of benzo[h]quinoline-3-carbox-amide. Acta crystallographica. Section E, Crystallographic communications 75 (Pt 12) (2019)
Steffen Vojacek, Lukas Schulig, Nathalie Wössner, Norman Geist, Walter Langel, Manfred Jung, Dennis Schade, Andreas Link
Tetrahydroindoles as Multipurpose Screening Compounds and Novel Sirtuin Inhibitors. ChemMedChem 14 (8) (2019)
Abdrrahman Shemsu Surur, Lukas Schulig, Andreas Link
Interconnection of sulfides and sulfoxides in medicinal chemistry. Archiv der Pharmazie 352 (1) (2018)
Steffen Vojacek, Katja Beese, Zayan Alhalabi, Sören Swyter, Anja Bodtke, Carola Schulzke, Manfred Jung, Wolfgang Sippl, Andreas Link
Three-Component Aminoalkylations Yielding Dihydronaphthoxazine-Based Sirtuin Inhibitors: Scaffold Modification and Exploration of Space for Polar Side-Chains. Archiv der Pharmazie 350 (7) (2017)
Andreas Link, Christa E Müller
G-Protein-Coupled Receptors: Sustained Signaling via Intracellular Megaplexes and Pathway-Specific Drugs. Angewandte Chemie (International ed. in English) 55 (52) (2016)
Nicole Rüger, Georg Michael Fassauer, Christian Bock, Thomas Emmrich, Anja Bodtke, Andreas Link
Substituted tetrazoles as multipurpose screening compounds. Molecular diversity 21 (1) (2016)

Andreas Link.css-eqlu8i{font-size:small;padding-left:4px;} (A Link)

Publication Activity (10 Years)

Top Topics

Top Venues

Andreas Link (A Link)