Luke L Lairson (Luke Lairson)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 24

Top Venues

Science (New York, N.Y.)

Biochemistry

Journal of medicinal chemistry

Nature chemical biology

Scripps Research Institute

University of British Columbia (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Scripps Research Institute Apr 01 2017

United States

Associate Professor :: Chemistry

Education History

University of British Columbia

Canada

PHD :: Chemistry

University of Guelph

Canada

BSC :: Chemistry and Biochemistry

Publications

Andrew J Ambrose, Christopher J Zerio, Jared Sivinski, Xiaoyi Zhu, Jack Godek, Jonathan L Sanchez, May Khanna, Rajesh Khanna, Luke L Lairson, Donna D Zhang, Eli Chapman
Human Hsp70 Substrate-Binding Domains Recognize Distinct Client Proteins. Biochemistry (2024)
Jaroslav Zak, Isaraphorn Pratumchai, Brett S Marro, Kristi L Marquardt, Reza Beheshti Zavareh, Luke L Lairson, Michael B A Oldstone, Judith A Varner, Livia Hegerova, Qing Cao, Umar Farooq, Vaishalee P Kenkre, Veronika Bachanova, John R Teijaro
JAK inhibition enhances checkpoint blockade immunotherapy in patients with Hodgkin lymphoma. Science (New York, N.Y.) 384 (6702) (2024)
Jaroslav Zak, Isaraphorn Pratumchai, Brett S Marro, Kristi L Marquardt, Reza Beheshti Zavareh, Luke L Lairson, Michael B A Oldstone, Judith A Varner, Livia Hegerova, Qing Cao, Umar Farooq, Vaishalee P Kenkre, Veronika Bachanova, John R Teijaro
JAK inhibition enhances checkpoint blockade immunotherapy in patients with Hodgkin lymphoma. Science (New York, N.Y.) 384 (6702) (2024)
Jaroslav Zak, Isaraphorn Pratumchai, Brett S Marro, Kristi L Marquardt, Reza Beheshti Zavareh, Luke L Lairson, Michael B A Oldstone, Judith A Varner, Livia Hegerova, Qing Cao, Umar Farooq, Vaishalee P Kenkre, Veronika Bachanova, John R Teijaro
JAK inhibition enhances checkpoint blockade immunotherapy in patients with Hodgkin lymphoma. Science (New York, N.Y.) 384 (6702) (2024)
Andrew J Ambrose, Christopher J Zerio, Jared Sivinski, Xiaoyi Zhu, Jack Godek, Jonathan L Sanchez, May Khanna, Rajesh Khanna, Luke L Lairson, Donna D Zhang, Eli Chapman
Human Hsp70 Substrate-Binding Domains Recognize Distinct Client Proteins. Biochemistry 63 (3) (2024)
Jaroslav Zak, Isaraphorn Pratumchai, Brett S Marro, Kristi L Marquardt, Reza Beheshti Zavareh, Luke L Lairson, Michael B A Oldstone, Judith A Varner, Livia Hegerova, Qing Cao, Umar Farooq, Vaishalee P Kenkre, Veronika Bachanova, John R Teijaro
JAK inhibition enhances checkpoint blockade immunotherapy in patients with Hodgkin lymphoma. Science (New York, N.Y.) 384 (6702) (2024)
Jaroslav Zak, Isaraphorn Pratumchai, Brett S Marro, Kristi L Marquardt, Reza Beheshti Zavareh, Luke L Lairson, Michael B A Oldstone, Judith A Varner, Livia Hegerova, Qing Cao, Umar Farooq, Vaishalee P Kenkre, Veronika Bachanova, John R Teijaro
JAK inhibition enhances checkpoint blockade immunotherapy in patients with Hodgkin lymphoma. Science (New York, N.Y.) 384 (6702) (2024)
Jaroslav Zak, Isaraphorn Pratumchai, Brett S Marro, Kristi L Marquardt, Reza Beheshti Zavareh, Luke L Lairson, Michael B A Oldstone, Judith A Varner, Livia Hegerova, Qing Cao, Umar Farooq, Vaishalee P Kenkre, Veronika Bachanova, John R Teijaro
JAK inhibition enhances checkpoint blockade immunotherapy in patients with Hodgkin lymphoma. Science (New York, N.Y.) 384 (6702) (2024)
Jaroslav Zak, Isaraphorn Pratumchai, Brett S Marro, Kristi L Marquardt, Reza Beheshti Zavareh, Luke L Lairson, Michael B A Oldstone, Judith A Varner, Livia Hegerova, Qing Cao, Umar Farooq, Vaishalee P Kenkre, Veronika Bachanova, John R Teijaro
JAK inhibition enhances checkpoint blockade immunotherapy in patients with Hodgkin lymphoma. Science (New York, N.Y.) 384 (6702) (2024)
Andrew J Ambrose, Christopher J Zerio, Jared Sivinski, Xiaoyi Zhu, Jack Godek, Jonathan L Sanchez, May Khanna, Rajesh Khanna, Luke L Lairson, Donna D Zhang, Eli Chapman
Human Hsp70 Substrate-Binding Domains Recognize Distinct Client Proteins. Biochemistry 63 (3) (2024)
Xiaohui Zhao, Kathryn R Stein, Howard C Hang, Matthew E Griffin, Luke L Lairson, Howard C Hang
Chemoproteomics reveals microbiota-derived aromatic monoamine agonists for GPRC5A. Nature chemical biology (2023)
Junchen Tang, Weichao Li, Tzu-Yuan Chiu, Francisco Martínez-Peña, Zengwei Luo, Christine T Chong, Qijia Wei, Nathalia Gazaniga, Thomas J West, Yi Yang See, Luke L Lairson, Christopher G Parker, Phil S Baran
Author Correction: Synthesis of portimines reveals the basis of their anti-cancer activity. Nature (2023)
Thomas J West, Junfeng Bi, Francisco Martínez-Peña, Ellis J Curtis, Nathalia R Gazaniga, Paul S Mischel, Luke L Lairson
A Cell Type Selective YM155 Prodrug Targets Receptor-Interacting Protein Kinase 2 to Induce Brain Cancer Cell Death. Journal of the American Chemical Society (2023)
Ariana Sulpizio, Luke L Lairson
A new road to STING activation. Nature chemical biology (2023)
Junchen Tang, Weichao Li, Tzu-Yuan Chiu, Francisco Martínez-Peña, Zengwei Luo, Christine T Chong, Qijia Wei, Nathalia Gazaniga, Thomas J West, Yi Yang See, Luke L Lairson, Christopher G Parker, Phil S Baran
Synthesis of portimines reveals the basis of their anti-cancer activity. Nature (2023)
Andrew J Ambrose, Jared Sivinski, Christopher J Zerio, Xiaoyi Zhu, Jack Godek, Vlad K Kumirov, Teresa Coma Brujas, Joan Torra Garcia, Anandhan Annadurai, Cody J Schmidlin, Alyssa Werner, Taoda Shi, Reza Beheshti Zavareh, Luke L Lairson, Donna D Zhang, Eli Chapman
Discovery and Development of a Selective Inhibitor of the ER Resident Chaperone Grp78. Journal of medicinal chemistry 66 (1) (2022)
Andrew J Ambrose, Jared Sivinski, Christopher J Zerio, Xiaoyi Zhu, Jack Godek, Vlad K Kumirov, Teresa Coma Brujas, Joan Torra Garcia, Anandhan Annadurai, Cody J Schmidlin, Alyssa Werner, Taoda Shi, Reza Beheshti Zavareh, Luke L Lairson, Donna D Zhang, Eli Chapman
Discovery and Development of a Selective Inhibitor of the ER Resident Chaperone Grp78. Journal of medicinal chemistry 66 (1) (2022)
Andrew J Ambrose, Jared Sivinski, Christopher J Zerio, Xiaoyi Zhu, Jack Godek, Vlad K Kumirov, Teresa Coma Brujas, Joan Torra Garcia, Anandhan Annadurai, Cody J Schmidlin, Alyssa Werner, Taoda Shi, Reza Beheshti Zavareh, Luke L Lairson, Donna D Zhang, Eli Chapman
Discovery and Development of a Selective Inhibitor of the ER Resident Chaperone Grp78. Journal of medicinal chemistry (2022)
Andrew J Ambrose, Jared Sivinski, Christopher J Zerio, Xiaoyi Zhu, Jack Godek, Vlad K Kumirov, Teresa Coma Brujas, Joan Torra Garcia, Anandhan Annadurai, Cody J Schmidlin, Alyssa Werner, Taoda Shi, Reza Beheshti Zavareh, Luke L Lairson, Donna D Zhang, Eli Chapman
Discovery and Development of a Selective Inhibitor of the ER Resident Chaperone Grp78. Journal of medicinal chemistry 66 (1) (2022)
Rebekah J Karadeema, Sydney E Morris, Luke L Lairson, Ramanarayanan Krishnamurthy
Towards an Understanding of the Molecular Mechanisms of Variable Unnatural Base-Pair Behavior: A Biophysical Analysis of dNaM-dTPT3. Chemistry (Weinheim an der Bergstrasse, Germany) 27 (56) (2021)
Benjamin J Huffman, Shuming Chen, J Luca Schwarz, R Erik Plata, Emily N Chin, Luke L Lairson, Kendall N Houk, Ryan A Shenvi
Electronic complementarity permits hindered butenolide heterodimerization and discovery of novel cGAS/STING pathway antagonists. Nature chemistry 12 (3) (2020)
Emily N Chin, Chenguang Yu, Vincent F Vartabedian, Ying Jia, Manoj Kumar, Ana M Gamo, William Vernier, Sabrina H Ali, Mildred Kissai, Daniel C Lazar, Nhan Nguyen, Laura E Pereira, Brent Benish, Ashley K Woods, Sean B Joseph, Alan Chu, Kristen A Johnson, Philipp N Sander, Francisco Martínez-Peña, Eric N Hampton, Travis S Young, Dennis W Wolan, Arnab K Chatterjee, Peter G Schultz, H Michael Petrassi, John R Teijaro, Luke L Lairson
Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic. Science (New York, N.Y.) 369 (6506) (2020)
Natasha C Lucki, Genaro R Villa, Naja Vergani, Michael J Bollong, Brittney A Beyer, Jae Wook Lee, Justin L Anglin, Stephan H Spangenberg, Emily N Chin, Amandeep Sharma, Kevin Johnson, Philipp N Sander, Perry Gordon, Stephen L Skirboll, Heiko Wurdak, Peter G Schultz, Paul S Mischel, Luke L Lairson
A cell type-selective apoptosis-inducing small molecule for the treatment of brain cancer. Proceedings of the National Academy of Sciences of the United States of America 116 (13) (2019)
Melissa C Holt, Zahra Assar, Reza Beheshti Zavareh, Lin Lin, Justin Anglin, Oksana Mashadova, Daniel Haldar, Edouard Mullarky, Daniel M Kremer, Lewis C Cantley, Alec C Kimmelman, Adam J Stein, Luke L Lairson, Costas Andreas Lyssiotis
Biochemical Characterization and Structure-Based Mutational Analysis Provide Insight into the Binding and Mechanism of Action of Novel Aspartate Aminotransferase Inhibitors. Biochemistry 57 (47) (2018)

Luke L Lairson.css-eqlu8i{font-size:small;padding-left:4px;} (Luke Lairson)

Publication Activity (10 Years)

Top Topics

Top Venues

Luke L Lairson (Luke Lairson)