Angela Casini (A Casini)

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 52

Top Venues

Journal of medicinal chemistry

Chemistry (Weinheim an der Bergstrasse, Germany)

Inorganic chemistry

Angewandte Chemie (International ed. in English)

Technical University Munich

University of Florence (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Technical University Munich

Germany

Chair of Medicinal and Bioinorganic chemistry :: Chemistry

Cardiff University Oct 01 2015 - Sep 01 2019

United Kingdom

Chair of Medicinal and Bioinorganic chemistry :: Cardiff School of Chemistry

University of Groningen Sep 01 2011 - Oct 01 2015

Netherlands

Assistant Professor :: Groningen Research Institute of Pharmacy

Ecole Polytechnique Federale de Lausanne Sep 01 2008 - Aug 31 2011

Switzerland

Principal Investigator

Education History

University of Florence

Italy

PHD :: Chemistry

Publications

Sandra Deiser, Sebastian Fenzl, Victor König, Marike Drexler, Lydia M Smith, Madeleine E George, Roswitha Beck, Timothy H Witney, Shigeyoshi Inoue, Angela Casini
(SiFA)SeFe: A Hydrophilic Silicon-Based Fluoride Acceptor Enabling Versatile Peptidic Radiohybrid Tracers. Journal of medicinal chemistry 67 (16) (2024)
Philipp Weingarten, Sophie R Thomas, Ana Luiza de Andrade Querino, Kerstin Halama, Moritz Kränzlein, Angela Casini, Bernhard Rieger
A graft-to strategy of poly(vinylphosphonates) on dopazide-coated gold nanoparticles using in situ catalyst activation. RSC advances 14 (12) (2024)
Sandra Deiser, Sebastian Fenzl, Victor König, Marike Drexler, Lydia M Smith, Madeleine E George, Roswitha Beck, Timothy H Witney, Shigeyoshi Inoue, Angela Casini
(SiFA)SeFe: A Hydrophilic Silicon-Based Fluoride Acceptor Enabling Versatile Peptidic Radiohybrid Tracers. Journal of medicinal chemistry 67 (16) (2024)
Sandra Deiser, Sebastian Fenzl, Victor König, Marike Drexler, Lydia M Smith, Madeleine E George, Roswitha Beck, Timothy H Witney, Shigeyoshi Inoue, Angela Casini
(SiFA)SeFe: A Hydrophilic Silicon-Based Fluoride Acceptor Enabling Versatile Peptidic Radiohybrid Tracers. Journal of medicinal chemistry 67 (16) (2024)
Sandra Deiser, Sebastian Fenzl, Victor König, Marike Drexler, Lydia M Smith, Madeleine E George, Roswitha Beck, Timothy H Witney, Shigeyoshi Inoue, Angela Casini
(SiFA)SeFe: A Hydrophilic Silicon-Based Fluoride Acceptor Enabling Versatile Peptidic Radiohybrid Tracers. Journal of medicinal chemistry (2024)
Angela Casini, Alexander Pöthig
Metals in Cancer Research: Beyond Platinum Metallodrugs. ACS central science 10 (2) (2024)
Philipp Weingarten, Sophie R Thomas, Ana Luiza de Andrade Querino, Kerstin Halama, Moritz Kränzlein, Angela Casini, Bernhard Rieger
A graft-to strategy of poly(vinylphosphonates) on dopazide-coated gold nanoparticles using in situ catalyst activation. RSC advances 14 (12) (2024)
Angela Casini, Alexander Pöthig
Metals in Cancer Research: Beyond Platinum Metallodrugs. ACS central science 10 (2) (2024)
James S Craig, Lazaros Melidis, Hugo D Williams, Samuel J Dettmer, Alexandra A Heidecker, Philipp J Altmann, Shengyang Guan, Callum Campbell, Douglas F Browning, Roland K O Sigel, Silke Johannsen, Ross T Egan, Brech Aikman, Angela Casini, Alexander Pöthig, Michael J Hannon
Organometallic Pillarplexes That Bind DNA 4-Way Holliday Junctions and Forks. Journal of the American Chemical Society (2023)
Sandra Deiser, Marike Drexler, Guillermo Moreno-Alcántar, Maximilian Irl, Claudia Schmidt, Thomas Günther, Angela Casini
Synthesis of 177 Lu-Labeled, Somatostatin-2 Receptor-Targeted Metalla-Assemblies: Challenges in the Design of Supramolecular Radiotherapeutics. Inorganic chemistry (2023)
Nilima Manoj Kumar, Patrick Gruhs, Angela Casini, Frank Biedermann, Guillermo Moreno-Alcántar, Pierre Picchetti
Electrochemical Detection of Drugs via a Supramolecular Cucurbit[7]uril-Based Indicator Displacement Assay. ACS sensors (2023)
Valeria Scalcon, Riccardo Bonsignore, Jana Aupič, Sophie R Thomas, Alessandra Folda, Alexandra A Heidecker, Alexander Pöthig, Alessandra Magistrato, Angela Casini, Maria Pia Rigobello
Exploring the Anticancer Activity of Tamoxifen-Based Metal Complexes Targeting Mitochondria. Journal of medicinal chemistry (2023)
Jing-Jing Zhang, Qi-Jie Xu, Claudia Schmidt, Mohamed A Abu El Maaty, Jinglin Song, Chunqiu Yu, Jun Zhou, Kang Han, Hao Sun, Angela Casini, Ingo Ott, Stefan Wölfl
Elucidating the Multimodal Anticancer Mechanism of an Organometallic Terpyridine Platinum(II) N-Heterocyclic Carbene Complex against Triple-Negative Breast Cancer In Vitro and In Vivo. Journal of medicinal chemistry 66 (6) (2023)
Jing-Jing Zhang, Qi-Jie Xu, Claudia Schmidt, Mohamed A Abu El Maaty, Jinglin Song, Chunqiu Yu, Jun Zhou, Kang Han, Hao Sun, Angela Casini, Ingo Ott, Stefan Wölfl
Elucidating the Multimodal Anticancer Mechanism of an Organometallic Terpyridine Platinum(II) N-Heterocyclic Carbene Complex against Triple-Negative Breast Cancer In Vitro and In Vivo. Journal of medicinal chemistry 66 (6) (2023)
Guillermo Moreno-Alcántar, Pierre Picchetti, Angela Casini
Gold Complexes in Anticancer Therapy: From New Design Principles to Particle-Based Delivery Systems. Angewandte Chemie (International ed. in English) (2023)
Jing-Jing Zhang, Qi-Jie Xu, Claudia Schmidt, Mohamed A Abu El Maaty, Jinglin Song, Chunqiu Yu, Jun Zhou, Kang Han, Hao Sun, Angela Casini, Ingo Ott, Stefan Wölfl
Elucidating the Multimodal Anticancer Mechanism of an Organometallic Terpyridine Platinum(II) N-Heterocyclic Carbene Complex against Triple-Negative Breast Cancer In Vitro and In Vivo. Journal of medicinal chemistry (2023)
Thomas Günther, Matthias Konrad, León Stopper, Jan-Philip Kunert, Sebastian Fischer, Roswitha Beck, Angela Casini, Hans-Jürgen Wester
Optimization of the Pharmacokinetic Profile of [ 99m Tc]Tc-N 4 -Bombesin Derivatives by Modification of the Pharmacophoric Gln-Trp Sequence. Pharmaceuticals (Basel, Switzerland) 15 (9) (2022)
Guillermo Moreno-Alcántar, Angela Casini
Bioinorganic supramolecular coordination complexes and their biomedical applications. FEBS letters (2022)
Sophie R Thomas, Wenjie Yang, David J Morgan, Thomas E Davies, Jiao Jiao Li, Roland A Fischer, Jun Huang, Nikolaos Dimitratos, Angela Casini
Bottom-up Synthesis of Water-Soluble Gold Nanoparticles Stabilized by N-Heterocyclic Carbenes: From Structural Characterization to Applications. Chemistry (Weinheim an der Bergstrasse, Germany) 28 (56) (2022)
Claudia Schmidt, Michael Zollo, Riccardo Bonsignore, Angela Casini, Stephan M Hacker
Competitive profiling of ligandable cysteines in Staphylococcus aureus with an organogold compound. Chemical communications (Cambridge, England) 58 (36) (2022)
Raúl Cosialls, Cristina Simó, Salvador Borrós, Vanessa Gómez-Vallejo, Claudia Schmidt, Jordi Llop, Ana Belén Cuenca, Angela Casini
PET Imaging of Self-Assembled 18 F-Labelled Pd 2 L 4 Metallacages for Anticancer Drug Delivery. Chemistry (Weinheim an der Bergstrasse, Germany) (2022)
Brech Aikman, Riccardo Bonsignore, Ben Woods, Daniel Doellerer, Riccardo Scotti, Claudia Schmidt, Alexandra A Heidecker, Alexander Pöthig, Edward John Sayers, Arwyn Tomos Jones, Angela Casini
Highly-fluorescent BODIPY-functionalised metallacages as drug delivery systems: synthesis, characterisation and cellular accumulation studies. Dalton transactions (Cambridge, England : 2003) 51 (19) (2022)
Catarina Pimpão, Darren Wragg, Riccardo Bonsignore, Brech Aikman, Per Amstrup Pedersen, Stefano Leoni, Graça Soveral, Angela Casini
Mechanisms of irreversible aquaporin-10 inhibition by organogold compounds studied by combined biophysical methods and atomistic simulations. Metallomics : integrated biometal science 13 (9) (2022)
Sarah V Dummert, Haneesh Saini, Mian Zahid Hussain, Khushboo Yadava, Kolleboyina Jayaramulu, Angela Casini, Roland A Fischer
Cyclodextrin metal-organic frameworks and derivatives: recent developments and applications. Chemical Society reviews 51 (12) (2022)
Clemens Kaußler, Darren Wragg, Claudia Schmidt, Guillermo Moreno-Alcántar, Christian Jandl, Johannes Stephan, Roland A Fischer, Stefano Leoni, Angela Casini, Riccardo Bonsignore
"Dynamical Docking" of Cyclic Dinuclear Au(I) Bis-N-heterocyclic Complexes Facilitates Their Binding to G-Quadruplexes. Inorganic chemistry (2022)
Parichita Chakraborty, Dorenda Oosterhuis, Riccardo Bonsignore, Angela Casini, Peter Olinga, Dirk-Jan Scheffers
An Organogold Compound as Potential Antimicrobial Agent against Drug-Resistant Bacteria: Initial Mechanistic Insights. ChemMedChem 16 (19) (2021)
Ben Woods, Rúben D M Silva, Claudia Schmidt, Darren Wragg, Marco Cavaco, Vera Neves, Vera F C Ferreira, Lurdes Gano, Tânia S Morais, Filipa Mendes, João D G Correia, Angela Casini
Bioconjugate Supramolecular Pd2+ Metallacages Penetrate the Blood Brain Barrier In Vitro and In Vivo. Bioconjugate chemistry 32 (7) (2021)
Shengyang Guan, David C Mayer, Christian Jandl, Sebastian J Weishäupl, Angela Casini, Alexander Pöthig
Investigation of Solvatomorphism and Its Photophysical Implications for Archetypal Trinuclear Au3(1-Methylimidazolate)3. Molecules (Basel, Switzerland) 26 (15) (2021)
Holly M Craven, Riccardo Bonsignore, Vasileios P Lenis, Nicolo Santi, Daniel Berrar, Martin T Swain, Helen Whiteland, Angela Casini, Karl F Hoffmann
Identifying and validating the presence of Guanine-Quadruplexes (G4) within the blood fluke parasite Schistosoma mansoni. PLoS neglected tropical diseases 15 (2) (2021)
Riccardo Bonsignore, Sophie R Thomas, Mathilde Rigoulet, Christian Jandl, Alexander Pöthig, Didier Bourissou, Giampaolo Barone, Angela Casini
C-C Cross-Couplings from a Cyclometalated Au(III) C ∧ N Complex: Mechanistic Insights and Synthetic Developments. Chemistry (Weinheim an der Bergstrasse, Germany) 27 (57) (2021)
Eva J Ge, Ashley I Bush, Angela Casini, Paul A Cobine, Justin R Cross, Gina M DeNicola, Q Ping Dou, Katherine J Franz, Vishal M Gohil, Sanjeev Gupta, Stephen G Kaler, Svetlana Lutsenko, Vivek Mittal, Michael J Petris, Roman S Polishchuk, Martina Ralle, Michael L Schilsky, Nicholas K Tonks, Linda T Vahdat, Linda Van Aelst, Dan Xi, Peng Yuan, Donita C Brady, Christopher J Chang
Connecting copper and cancer: from transition metal signalling to metalloplasia. Nature reviews. Cancer (2021)
Maria V Babak, Kai Ren Chong, Peter Rapta, Markella Zannikou, Hui Min Tang, Lisa Reichert, Meng Rui Chang, Vladimir Kushnarev, Petra Heffeter, Samuel M Meier-Menches, Zhi Chiaw Lim, Jian Yu Yap, Angela Casini, Irina V Balyasnikova, Wee Han Ang
Interfering with Metabolic Profile of Triple-Negative Breast Cancers Using Rationally Designed Metformin Prodrugs. Angewandte Chemie (International ed. in English) 60 (24) (2021)
Farzana Sabir, Antonella Di Pizio, Maria C Loureiro-Dias, Angela Casini, Graça Soveral, Catarina Prista
Insights into the Selectivity Mechanisms of Grapevine NIP Aquaporins. International journal of molecular sciences 21 (18) (2020)
Karen Minori, Letícia B Rosa, Riccardo Bonsignore, Angela Casini, Danilo Ciccone Miguel
Comparing the Antileishmanial Activity of Gold(I) and Gold(III) Compounds in L. amazonensis and L. braziliensis in Vitro. ChemMedChem 15 (22) (2020)
Samuel M Meier-Menches, Benjamin Neuditschko, Katja Zappe, Martin Schaier, Marlene C Gerner, Klaus Georg Schmetterer, Giorgia Del Favero, Riccardo Bonsignore, Margit Cichna-Markl, Gunda Koellensperger, Angela Casini, Christopher Gerner
An Organometallic Gold(I) Bis-N-Heterocyclic Carbene Complex with Multimodal Activity in Ovarian Cancer Cells. Chemistry (Weinheim an der Bergstrasse, Germany) 26 (67) (2020)
Darren Wragg, Stefano Leoni, Angela Casini
Aquaporin-driven hydrogen peroxide transport: a case of molecular mimicry? RSC chemical biology 1 (5) (2020)
Riccardo Bonsignore, Sophie R Thomas, Wim T Klooster, Simon J Coles, Robert L Jenkins, Didier Bourissou, Giampaolo Barone, Angela Casini
Carbon-Phosphorus Coupling from C^N Cyclometalated AuIII Complexes. Chemistry (Weinheim an der Bergstrasse, Germany) 26 (19) (2020)
Samuel M Meier-Menches, Angela Casini
Design Strategies and Medicinal Applications of Metal-Peptidic Bioconjugates. Bioconjugate chemistry 31 (5) (2020)
Sophie R Thomas, Riccardo Bonsignore, Jorge Sánchez Escudero, Samuel M Meier-Menches, Christopher M Brown, Michael O Wolf, Giampaolo Barone, Louis Y P Luk, Angela Casini
Exploring the Chemoselectivity towards Cysteine Arylation by Cyclometallated AuIII Compounds: New Mechanistic Insights. Chembiochem : a European journal of chemical biology 21 (21) (2020)
Margot N Wenzel, Riccardo Bonsignore, Sophie R Thomas, Didier Bourissou, Giampaolo Barone, Angela Casini
Cyclometalated AuIII Complexes for Cysteine Arylation in Zinc Finger Protein Domains: towards Controlled Reductive Elimination. Chemistry (Weinheim an der Bergstrasse, Germany) 25 (32) (2019)
Natalia Estrada-Ortiz, Elena Lopez-Gonzales, Ben Woods, Stefan Stürup, Inge A M de Graaf, Geny M M Groothuis, Angela Casini
Ex vivo toxicological evaluation of experimental anticancer gold(i) complexes with lansoprazole-type ligands. Toxicology research 8 (6) (2019)
Margot N Wenzel, Andreia F Mósca, Valentina Graziani, Brech Aikman, Sophie R Thomas, Andreia de Almeida, James A Platts, Nazzareno Re, Cecilia Coletti, Alessandro Marrone, Graça Soveral, Angela Casini
Insights into the Mechanisms of Aquaporin-3 Inhibition by Gold(III) Complexes: the Importance of Non-Coordinative Adduct Formation. Inorganic chemistry 58 (3) (2019)
Darren Wragg, Andreia de Almeida, Angela Casini, Stefano Leoni
Unveiling the Mechanisms of Aquaglyceroporin-3 Water and Glycerol Permeation by Metadynamics. Chemistry (Weinheim an der Bergstrasse, Germany) 25 (37) (2019)
Silvia Carboni, Antonio Zucca, Sergio Stoccoro, Laura Maiore, Massimiliano Arca, Fabrizio Ortu, Christian Artner, Bernhard K Keppler, Samuel M Meier-Menches, Angela Casini, Maria Agostina Cinellu
New Variations on the Theme of Gold(III) C∧N∧N Cyclometalated Complexes as Anticancer Agents: Synthesis and Biological Characterization. Inorganic chemistry 57 (23) (2018)
J Han, A Schmidt, T Zhang, H Permentier, G M M Groothuis, R Bischoff, Fritz E Kühn, P Horvatovich, Angela Casini
Bioconjugation strategies to couple supramolecular exo-functionalized palladium cages to peptides for biomedical applications. Chemical communications (Cambridge, England) 53 (8) (2018)
Andreia de Almeida, Andreia F Mósca, Darren Wragg, Margot Wenzel, Paul Kavanagh, Giampaolo Barone, Stefano Leoni, Graça Soveral, Angela Casini
The mechanism of aquaporin inhibition by gold compounds elucidated by biophysical and computational methods. Chemical communications (Cambridge, England) 53 (27) (2018)
Darren Wragg, Andreia de Almeida, Riccardo Bonsignore, Fritz E Kühn, Stefano Leoni, Angela Casini
On the Mechanism of Gold/NHC Compounds Binding to DNA G-Quadruplexes: Combined Metadynamics and Biophysical Methods. Angewandte Chemie (International ed. in English) 57 (44) (2018)
Jiaying Han, Andreas F B Räder, Florian Reichart, Brech Aikman, Margot N Wenzel, Ben Woods, Michael Weinmüller, Beatrice S Ludwig, Stefan Stürup, Geny M M Groothuis, Hjalmar P Permentier, Rainer Bischoff, Horst Kessler, Peter L Horvatovich, Angela Casini
Bioconjugation of Supramolecular Metallacages to Integrin Ligands for Targeted Delivery of Cisplatin. Bioconjugate chemistry 29 (11) (2018)
Andreia F Mósca, Andreia de Almeida, Darren Wragg, Ana Paula Martins, Farzana Sabir, Stefano Leoni, Teresa F Moura, Catarina Prista, Angela Casini, Graça Soveral
Molecular Basis of Aquaporin-7 Permeability Regulation by pH. Cells 7 (11) (2018)
Özden Karaca, Valeria Scalcon, Samuel M Meier-Menches, Riccardo Bonsignore, Jurriaan M J L Brouwer, Federica Tonolo, Alessandra Folda, Maria Pia Rigobello, Fritz E Kühn, Angela Casini
Characterization of Hydrophilic Gold(I) N-Heterocyclic Carbene (NHC) Complexes as Potent TrxR Inhibitors Using Biochemical and Mass Spectrometric Approaches. Inorganic chemistry 56 (22) (2017)
Sarah Spreckelmeyer, Natalia Estrada-Ortiz, Gerian G H Prins, Margot van der Zee, Bente Gammelgaard, Stefan Stürup, Inge A M de Graaf, Geny M M Groothuis, Angela Casini
On the toxicity and transport mechanisms of cisplatin in kidney tissues in comparison to a gold-based cytotoxic agent. Metallomics : integrated biometal science 9 (12) (2017)
Angela Casini, Benjamin Woods, Margot Wenzel
The Promise of Self-Assembled 3D Supramolecular Coordination Complexes for Biomedical Applications. Inorganic chemistry 56 (24) (2017)

Angela Casini.css-eqlu8i{font-size:small;padding-left:4px;} (A Casini)

Publication Activity (10 Years)

Top Topics

Top Venues

Angela Casini (A Casini)