Karl F Hoffmann (K F Hoffmann)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 25

Top Topics

Toxoplasma Gondii

Dendritic Cells

Drosophila Melanogaster

Top Venues

ACS infectious diseases

PLoS neglected tropical diseases

Wellcome open research

This page only lists publications with an associated author ORCID identifier.

Publications

Nicola Caldwell, Rana Afshar, Beatriz Baragaña, Amaya L Bustinduy, Conor R Caffrey, James J Collins, Daniela Fusco, Amadou Garba, Mark Gardner, Mireille Gomes, Karl F Hoffmann, Michael Hsieh, Nathan C Lo, Case W MacNamara, Justin Komguep Nono, Gilda Padalino, Kevin D Read, Meta Roestenberg, Thomas Spangenberg, Sabine Specht, Ian H Gilbert
Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022. ACS infectious diseases (2023)
Nicola Caldwell, Rana Afshar, Beatriz Baragaña, Amaya L Bustinduy, Conor R Caffrey, James J Collins, Daniela Fusco, Amadou Garba, Mark Gardner, Mireille Gomes, Karl F Hoffmann, Michael Hsieh, Nathan C Lo, Case W MacNamara, Justin Komguep Nono, Gilda Padalino, Kevin D Read, Meta Roestenberg, Thomas Spangenberg, Sabine Specht, Ian H Gilbert
Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022. ACS infectious diseases 9 (5) (2023)
Nicola Caldwell, Rana Afshar, Beatriz Baragaña, Amaya L Bustinduy, Conor R Caffrey, James J Collins, Daniela Fusco, Amadou Garba, Mark Gardner, Mireille Gomes, Karl F Hoffmann, Michael Hsieh, Nathan C Lo, Case W MacNamara, Justin Komguep Nono, Gilda Padalino, Kevin D Read, Meta Roestenberg, Thomas Spangenberg, Sabine Specht, Ian H Gilbert
Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022. ACS infectious diseases 9 (5) (2023)
Nicola Caldwell, Rana Afshar, Beatriz Baragaña, Amaya L Bustinduy, Conor R Caffrey, James J Collins, Daniela Fusco, Amadou Garba, Mark Gardner, Mireille Gomes, Karl F Hoffmann, Michael Hsieh, Nathan C Lo, Case W MacNamara, Justin Komguep Nono, Gilda Padalino, Kevin D Read, Meta Roestenberg, Thomas Spangenberg, Sabine Specht, Ian H Gilbert
Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022. ACS infectious diseases 9 (5) (2023)
Matthias Schiedel, Darius J B McArdle, Gilda Padalino, Anthony K C Chan, Josephine Forde-Thomas, Michael McDonough, Helen Whiteland, Manfred Beckmann, Rosa Cookson, Karl F Hoffmann, Stuart J Conway
Small Molecule Ligands of the BET-like Bromodomain, Sm BRD3, Affect Schistosoma mansoni Survival, Oviposition, and Development. Journal of medicinal chemistry (2023)
Gilda Padalino, Cassandra A Celatka, Hugh Y Rienhoff, Jay H Kalin, Philip A Cole, Damien Lassalle, Josephine Forde-Thomas, Iain W Chalmers, Andrea Brancale, Christoph Grunau, Karl F Hoffmann
Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes. Wellcome open research 8 (2023)
Nicola Caldwell, Rana Afshar, Beatriz Baragaña, Amaya L Bustinduy, Conor R Caffrey, James J Collins, Daniela Fusco, Amadou Garba, Mark Gardner, Mireille Gomes, Karl F Hoffmann, Michael Hsieh, Nathan C Lo, Case W MacNamara, Justin Komguep Nono, Gilda Padalino, Kevin D Read, Meta Roestenberg, Thomas Spangenberg, Sabine Specht, Ian H Gilbert
Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022. ACS infectious diseases (2023)
Nicola Caldwell, Rana Afshar, Beatriz Baragaña, Amaya L Bustinduy, Conor R Caffrey, James J Collins, Daniela Fusco, Amadou Garba, Mark Gardner, Mireille Gomes, Karl F Hoffmann, Michael Hsieh, Nathan C Lo, Case W MacNamara, Justin Komguep Nono, Gilda Padalino, Kevin D Read, Meta Roestenberg, Thomas Spangenberg, Sabine Specht, Ian H Gilbert
Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022. ACS infectious diseases 9 (5) (2023)
Nicola Caldwell, Rana Afshar, Beatriz Baragaña, Amaya L Bustinduy, Conor R Caffrey, James J Collins, Daniela Fusco, Amadou Garba, Mark Gardner, Mireille Gomes, Karl F Hoffmann, Michael Hsieh, Nathan C Lo, Case W MacNamara, Justin Komguep Nono, Gilda Padalino, Kevin D Read, Meta Roestenberg, Thomas Spangenberg, Sabine Specht, Ian H Gilbert
Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022. ACS infectious diseases 9 (5) (2023)
Nicola Caldwell, Rana Afshar, Beatriz Baragaña, Amaya L Bustinduy, Conor R Caffrey, James J Collins, Daniela Fusco, Amadou Garba, Mark Gardner, Mireille Gomes, Karl F Hoffmann, Michael Hsieh, Nathan C Lo, Case W MacNamara, Justin Komguep Nono, Gilda Padalino, Kevin D Read, Meta Roestenberg, Thomas Spangenberg, Sabine Specht, Ian H Gilbert
Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022. ACS infectious diseases (2023)
Emma L Houlder, A H Costain, I Nambuya, S L Brown, Jan Pieter R Koopman, M C C Langenberg, J J Janse, M A Hoogerwerf, A J L Ridley, J E Forde-Thomas, S A P Colombo, B M F Winkel, A A Galdon, Karl F Hoffmann, P C Cook, Meta Roestenberg, H Mpairwe, Andrew S MacDonald
Pulmonary inflammation promoted by type-2 dendritic cells is a feature of human and murine schistosomiasis. Nature communications 14 (1) (2023)
Nicola Caldwell, Rana Afshar, Beatriz Baragaña, Amaya L Bustinduy, Conor R Caffrey, James J Collins, Daniela Fusco, Amadou Garba, Mark Gardner, Mireille Gomes, Karl F Hoffmann, Michael Hsieh, Nathan C Lo, Case W MacNamara, Justin Komguep Nono, Gilda Padalino, Kevin D Read, Meta Roestenberg, Thomas Spangenberg, Sabine Specht, Ian H Gilbert
Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022. ACS infectious diseases (2023)
Avril Coghlan, Gilda Padalino, Noel M O'Boyle, Karl F Hoffmann, Matthew Berriman
Identification of anti-schistosomal, anthelmintic and anti-parasitic compounds curated and text-mined from the scientific literature. Wellcome open research 7 (2022)
Benjamin J Hulme, Kathrin K Geyer, Josephine E Forde-Thomas, Gilda Padalino, Dylan Wyn Phillips, Wannaporn Ittiprasert, Shannon E Karinshak, Victoria H Mann, Iain W Chalmers, Paul J Brindley, Cornelis H Hokke, Karl F Hoffmann
Schistosoma mansoni α-N-acetylgalactosaminidase (SmNAGAL) regulates coordinated parasite movement and egg production. PLoS pathogens 18 (1) (2022)
Frederick A Partridge, Carole J R Bataille, Ruth Forman, Amy E Marriott, Josephine Forde-Thomas, Cécile Häberli, Ria L Dinsdale, James D B O'Sullivan, Nicky J Willis, Graham M Wynne, Helen Whiteland, John Archer, Andrew Steven, Jennifer Keiser, Joseph D Turner, Karl F Hoffmann, Mark J Taylor, Kathryn J Else, Angela J Russell, David B Sattelle
Structural Requirements for Dihydrobenzoxazepinone Anthelmintics: Actions against Medically Important and Model Parasites: Trichuris muris, Brugia malayi, Heligmosomoides polygyrus, and Schistosoma mansoni. ACS infectious diseases 7 (5) (2021)
Thomas A Gasan, Marije E Kuipers, Grisial H Roberts, Gilda Padalino, Josephine E Forde-Thomas, Shona Wilson, Jakub Wawrzyniak, Edridah M Tukahebwa, Karl F Hoffmann, Iain W Chalmers
Schistosoma mansoni Larval Extracellular Vesicle protein 1 (SmLEV1) is an immunogenic antigen found in EVs released from pre-acetabular glands of invading cercariae. PLoS neglected tropical diseases 15 (11) (2021)
Holly M Craven, Riccardo Bonsignore, Vasileios P Lenis, Nicolo Santi, Daniel Berrar, Martin T Swain, Helen Whiteland, Angela Casini, Karl F Hoffmann
Identifying and validating the presence of Guanine-Quadruplexes (G4) within the blood fluke parasite Schistosoma mansoni. PLoS neglected tropical diseases 15 (2) (2021)
Lauren M Webb, Alexander T Phythian-Adams, Alice H Costain, Sheila L Brown, Rachel J Lundie, Josephine Forde-Thomas, Peter Charles Cook, Lucy H Jackson-Jones, Angela K Marley, Hermelijn H Smits, Karl F Hoffmann, Elia D Tait Wojno, Andrew S MacDonald
Plasmacytoid Dendritic Cells Facilitate Th Cell Cytokine Responses throughout Schistosoma mansoni Infection. ImmunoHorizons 5 (8) (2021)
Helen Whiteland, Alessandra Crusco, Lisa W Bloemberg, Jamie Tibble-Howlings, Josephine E Forde-Thomas, Avril Coghlan, Patrick J Murphy, Karl F Hoffmann
Quorum sensing N-Acyl homoserine lactones are a new class of anti-schistosomal. PLoS neglected tropical diseases 14 (10) (2020)
Marije E Kuipers, Esther N M Nolte-'t Hoen, Alwin J van der Ham, Arifa Ozir-Fazalalikhan, D Linh Nguyen, Clarize M de Korne, Roman I Koning, John J Tomes, Karl F Hoffmann, Hermelijn H Smits, Cornelis H Hokke
DC-SIGN mediated internalisation of glycosylated extracellular vesicles from Schistosoma mansoni increases activation of monocyte-derived dendritic cells. Journal of extracellular vesicles 9 (1) (2020)
Alessandra Crusco, Helen Whiteland, Rafael Baptista, Josephine E Forde-Thomas, Manfred Beckmann, Luis A J Mur, Robert J Nash, Andrew D Westwell, Karl F Hoffmann
Antischistosomal Properties of Sclareol and Its Heck-Coupled Derivatives: Design, Synthesis, Biological Evaluation, and Untargeted Metabolomics. ACS infectious diseases 5 (7) (2019)
Kezia C L Whatley, Gilda Padalino, Helen Whiteland, Kathrin K Geyer, Benjamin J Hulme, Iain W Chalmers, Josephine Forde-Thomas, Salvatore Ferla, Andrea Brancale, Karl F Hoffmann
The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets. PLoS neglected tropical diseases 13 (11) (2019)
David Roquis, Aaron Taudt, Kathrin K Geyer, Gilda Padalino, Karl F Hoffmann, Nancy E Holroyd, Matthew Berriman, Benoît Aliaga, Cristian Chaparro, Christoph Grunau, Ronaldo de Carvalho Augusto
Histone methylation changes are required for life cycle progression in the human parasite Schistosoma mansoni. PLoS pathogens 14 (5) (2018)
Kathrin K Geyer, Sabrina E Munshi, Helen L Whiteland, Narcís Fernandez-Fuentes, Dylan Wyn Phillips, Karl F Hoffmann
Methyl-CpG-binding (SmMBD2/3) and chromobox (SmCBX) proteins are required for neoblast proliferation and oviposition in the parasitic blood fluke Schistosoma mansoni. PLoS pathogens 14 (6) (2018)
Kathrin K Geyer, Umar H Niazi, David Duval, Céline Cosseau, Chad Tomlinson, Iain W Chalmers, Martin T Swain, David J Cutress, Utibe Bickham-Wright, Sabrina E Munshi, Christoph Grunau, Timothy P Yoshino, Karl F Hoffmann
The Biomphalaria glabrata DNA methylation machinery displays spatial tissue expression, is differentially active in distinct snail populations and is modulated by interactions with Schistosoma mansoni. PLoS neglected tropical diseases 11 (5) (2017)