Anthony G Coyne

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 18

Top Venues

Journal of medicinal chemistry

Angewandte Chemie (International ed. in English)

ACS infectious diseases

Angewandte Chemie (Weinheim an der Bergstrasse, Germany)

University of Cambridge

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Cambridge Nov 03 2015

United Kingdom

Senior Research Associate :: Chemistry

Publications

William J McCarthy, Sherine E Thomas, Tayo Olaleye, Jennifer A Boland, R Andres Floto, Glyn Williams, Thomas L Blundell, Anthony G Coyne, Chris Abell
A Fragment-Based Competitive 19 F LB-NMR Platform For Hotspot-Directed Ligand Profiling. Angewandte Chemie (International ed. in English) (2024)
William J McCarthy, Sherine E Thomas, Tayo Olaleye, Jennifer A Boland, R Andres Floto, Glyn Williams, Thomas L Blundell, Anthony G Coyne, Chris Abell
A Fragment-Based Competitive 19 F LB-NMR Platform For Hotspot-Directed Ligand Profiling. Angewandte Chemie (International ed. in English) 63 (37) (2024)
Jamal El Bakali, Michal Blaszczyk, Joanna C Evans, Jennifer A Boland, William J McCarthy, Imam Fathoni, Marcio Vinicius Bertacine Dias, Eachan O Johnson, Anthony G Coyne, Valerie Mizrahi, Thomas L Blundell, Chris Abell, Christina Spry
Chemical Validation of Mycobacterium tuberculosis Phosphopantetheine Adenylyltransferase Using Fragment Linking and CRISPR Interference. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 135 (17) (2023)
Jamal El Bakali, Michal Blaszczyk, Joanna C Evans, Jennifer A Boland, William J McCarthy, Imam Fathoni, Marcio Vinicius Bertacine Dias, Eachan O Johnson, Anthony G Coyne, Valerie Mizrahi, Thomas L Blundell, Chris Abell, Christina Spry
Chemical Validation of Mycobacterium tuberculosis Phosphopantetheine Adenylyltransferase Using Fragment Linking and CRISPR Interference. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 135 (17) (2023)
Jamal El Bakali, Michal Blaszczyk, Joanna C Evans, Jennifer A Boland, William J McCarthy, Imam Fathoni, Marcio Vinicius Bertacine Dias, Eachan O Johnson, Anthony G Coyne, Valerie Mizrahi, Thomas L Blundell, Chris Abell, Christina Spry
Chemical Validation of Mycobacterium tuberculosis Phosphopantetheine Adenylyltransferase Using Fragment Linking and CRISPR Interference. Angewandte Chemie (International ed. in English) (2023)
Marta Acebrón-García-de-Eulate, Joan Mayol-Llinàs, Matthew T O Holland, So Yeon Kim, Karen P Brown, Chiara Marchetti, Jeannine Hess, Ornella Di Pietro, Vitor Mendes, Chris Abell, R Andres Floto, Anthony G Coyne, Tom L Blundell
Discovery of Novel Inhibitors of Uridine Diphosphate- N -Acetylenolpyruvylglucosamine Reductase (MurB) from Pseudomonas aeruginosa , an Opportunistic Infectious Agent Causing Death in Cystic Fibrosis Patients. Journal of medicinal chemistry 65 (3) (2022)
Sitthivut Charoensutthivarakul, Sherine E Thomas, Amy Curran, Karen P Brown, Juan M Belardinelli, Andrew J Whitehouse, Marta Acebrón-García-de-Eulate, Jaspar Sangan, Subramanian G Gramani, Mary Jackson, Vitor Mendes, R Andres Floto, Tom L Blundell, Anthony G Coyne, Chris Abell
Development of Inhibitors of SAICAR Synthetase (PurC) from Mycobacterium abscessus Using a Fragment-Based Approach. ACS infectious diseases 8 (2) (2022)
William Addison, Martyn Frederickson, Anthony G Coyne, Chris Abell
Potential therapeutic targets from Mycobacterium abscessus ( Mab ): recently reported efforts towards the discovery of novel antibacterial agents to treat Mab infections. RSC medicinal chemistry 13 (4) (2022)
Vitor Mendes, Simon R Green, Joanna C Evans, Jeannine Hess, Michal Blaszczyk, Christina Spry, Owain Bryant, James Cory-Wright, Daniel S-H Chan, Pedro H M Torres, Zhe Wang, Navid Nahiyaan, Sandra O'Neill, Sebastian Damerow, John Post, Tracy Bayliss, Sasha L Lynch, Anthony G Coyne, Peter C Ray, Chris Abell, Kyu Y Rhee, Helena I M Boshoff, Clifton Earl Barry, Valerie Mizrahi, Paul G Wyatt, Thomas L Blundell
Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site. Nature communications 12 (1) (2021)
Joanna C Evans, Dinakaran Murugesan, John M Post, Vitor Mendes, Zhe Wang, Navid Nahiyaan, Sasha L Lynch, Stephen Thompson, Simon R Green, Peter C Ray, Jeannine Hess, Christina Spry, Anthony G Coyne, Chris Abell, Helena I M Boshoff, Paul G Wyatt, Kyu Y Rhee, Tom L Blundell, Clifton E Barry, Valerie Mizrahi
Targeting Mycobacterium tuberculosis CoaBC through Chemical Inhibition of 4'-Phosphopantothenoyl-l-cysteine Synthetase (CoaB) Activity. ACS infectious diseases 7 (6) (2021)
Mohamad Sabbah, Vitor Mendes, Robert G Vistal, David M G Dias, Monika Záhorszká, Katarína Mikušová, Jana Korduláková, Anthony G Coyne, Tom L Blundell, Chris Abell
Fragment-Based Design of Mycobacterium tuberculosis InhA Inhibitors. Journal of medicinal chemistry 63 (9) (2020)
João A Ribeiro, Alexander Hammer, Gerardo Andrés Libreros-Zúñiga, Sair M Chavez-Pacheco, Petros Tyrakis, Gabriel S de Oliveira, Timothy Kirkman, Jamal El Bakali, Silvana A Rocco, Mauricio L Sforça, Roberto Parise-Filho, Anthony G Coyne, Tom L Blundell, Chris Abell, Marcio Vinicius Bertacine Dias
Using a Fragment-Based Approach to Identify Alternative Chemical Scaffolds Targeting Dihydrofolate Reductase from Mycobacterium tuberculosis. ACS infectious diseases 6 (8) (2020)
Mohamad Sabbah, Vitor Mendes, Robert G Vistal, David M G Dias, Monika Záhorszká, Katarína Mikušová, Jana Korduláková, Anthony G Coyne, Tom L Blundell, Chris Abell
Correction to Fragment-Based Design of Mycobacterium tuberculosis InhA Inhibitors. Journal of medicinal chemistry 63 (15) (2020)
Andrew J Whitehouse, Sherine E Thomas, Karen P Brown, Alexander Fanourakis, Daniel S-H Chan, M Daben J Libardo, Vitor Mendes, Helena I M Boshoff, R Andres Floto, Chris Abell, Tom L Blundell, Anthony G Coyne
Development of Inhibitors against Mycobacterium abscessus tRNA (m1G37) Methyltransferase (TrmD) Using Fragment-Based Approaches. Journal of medicinal chemistry 62 (15) (2019)
Andrew J Whitehouse, M Daben J Libardo, Monica Kasbekar, Paul D Brear, Gerhard Fischer, Craig J Thomas, Clifton E Barry, Helena I M Boshoff, Anthony G Coyne, Chris Abell
Targeting of Fumarate Hydratase from Mycobacterium tuberculosis Using Allosteric Inhibitors with a Dimeric-Binding Mode. Journal of medicinal chemistry 62 (23) (2019)
Ana Trapero, Angela Pacitto, Vinayak Singh, Mohamad Sabbah, Anthony G Coyne, Valerie Mizrahi, Tom L Blundell, David B Ascher, Chris Abell
Fragment-Based Approach to Targeting Inosine-5'-monophosphate Dehydrogenase (IMPDH) from Mycobacterium tuberculosis. Journal of medicinal chemistry 61 (7) (2018)
Daniel S-H Chan, Madeline E Kavanagh, Kirsty J McLean, Andrew W Munro, Dijana Matak-Vinković, Anthony G Coyne, Chris Abell
Effect of DMSO on Protein Structure and Interactions Assessed by Collision-Induced Dissociation and Unfolding. Analytical chemistry 89 (18) (2017)
Daniel Shiu-Hin Chan, Vitor Mendes, Sherine E Thomas, Brendan N McConnell, Dijana Matak-Vinković, Anthony G Coyne, Tom L Blundell, Chris Abell
Fragment Screening against the EthR-DNA Interaction by Native Mass Spectrometry. Angewandte Chemie (International ed. in English) 56 (26) (2017)

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Publication Activity (10 Years)

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Anthony G Coyne