Chris Abell

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 28

Top Topics

Mass Spectrometry

Mycobacterium Tuberculosis

Top Venues

Journal of medicinal chemistry

Angewandte Chemie (International ed. in English)

ACS infectious diseases

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Simon R Stockwell, Duncan E Scott, Gerhard Fischer, Estrella Guarino, Timothy P C Rooney, Tzu-Shean Feng, Tommaso Moschetti, Rajavel Srinivasan, Esther Alza, Alice Asteian, Claudio Dagostin, Anna Alcaide, Mathieu Rocaboy, Beata Blaszczyk, Alicia Higueruelo, Xuelu Wang, Maxim Rossmann, Trevor R Perrior, Tom L Blundell, David R Spring, Grahame McKenzie, Chris Abell, John Skidmore, Ashok R Venkitaraman, Marko Hyvönen
Selective Aurora A-TPX2 Interaction Inhibitors Have In Vivo Efficacy as Targeted Antimitotic Agents. Journal of medicinal chemistry (2024)
Jamal El Bakali, Michal Blaszczyk, Joanna C Evans, Jennifer A Boland, William J McCarthy, Imam Fathoni, Marcio Vinicius Bertacine Dias, Eachan O Johnson, Anthony G Coyne, Valerie Mizrahi, Thomas L Blundell, Chris Abell, Christina Spry
Chemical Validation of Mycobacterium tuberculosis Phosphopantetheine Adenylyltransferase Using Fragment Linking and CRISPR Interference. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 135 (17) (2023)
Jamal El Bakali, Michal Blaszczyk, Joanna C Evans, Jennifer A Boland, William J McCarthy, Imam Fathoni, Marcio Vinicius Bertacine Dias, Eachan O Johnson, Anthony G Coyne, Valerie Mizrahi, Thomas L Blundell, Chris Abell, Christina Spry
Chemical Validation of Mycobacterium tuberculosis Phosphopantetheine Adenylyltransferase Using Fragment Linking and CRISPR Interference. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 135 (17) (2023)
Jamal El Bakali, Michal Blaszczyk, Joanna C Evans, Jennifer A Boland, William J McCarthy, Imam Fathoni, Marcio Vinicius Bertacine Dias, Eachan O Johnson, Anthony G Coyne, Valerie Mizrahi, Thomas L Blundell, Chris Abell, Christina Spry
Chemical Validation of Mycobacterium tuberculosis Phosphopantetheine Adenylyltransferase Using Fragment Linking and CRISPR Interference. Angewandte Chemie (International ed. in English) (2023)
Sara Abalde-Cela, Patricia Taladriz-Blanco, Marcelo Ganzarolli de Oliveira, Chris Abell
Author Correction: Droplet microfluidics for the highly controlled synthesis of branched gold nanoparticles. Scientific reports 12 (1) (2022)
Sitthivut Charoensutthivarakul, Sherine E Thomas, Amy Curran, Karen P Brown, Juan M Belardinelli, Andrew J Whitehouse, Marta Acebrón-García-de-Eulate, Jaspar Sangan, Subramanian G Gramani, Mary Jackson, Vitor Mendes, R Andres Floto, Tom L Blundell, Anthony G Coyne, Chris Abell
Development of Inhibitors of SAICAR Synthetase (PurC) from Mycobacterium abscessus Using a Fragment-Based Approach. ACS infectious diseases 8 (2) (2022)
William Addison, Martyn Frederickson, Anthony G Coyne, Chris Abell
Potential therapeutic targets from Mycobacterium abscessus ( Mab ): recently reported efforts towards the discovery of novel antibacterial agents to treat Mab infections. RSC medicinal chemistry 13 (4) (2022)
Vitor Mendes, Simon R Green, Joanna C Evans, Jeannine Hess, Michal Blaszczyk, Christina Spry, Owain Bryant, James Cory-Wright, Daniel S-H Chan, Pedro H M Torres, Zhe Wang, Navid Nahiyaan, Sandra O'Neill, Sebastian Damerow, John Post, Tracy Bayliss, Sasha L Lynch, Anthony G Coyne, Peter C Ray, Chris Abell, Kyu Y Rhee, Helena I M Boshoff, Clifton Earl Barry, Valerie Mizrahi, Paul G Wyatt, Thomas L Blundell
Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site. Nature communications 12 (1) (2021)
Joanna C Evans, Dinakaran Murugesan, John M Post, Vitor Mendes, Zhe Wang, Navid Nahiyaan, Sasha L Lynch, Stephen Thompson, Simon R Green, Peter C Ray, Jeannine Hess, Christina Spry, Anthony G Coyne, Chris Abell, Helena I M Boshoff, Paul G Wyatt, Kyu Y Rhee, Tom L Blundell, Clifton E Barry, Valerie Mizrahi
Targeting Mycobacterium tuberculosis CoaBC through Chemical Inhibition of 4'-Phosphopantothenoyl-l-cysteine Synthetase (CoaB) Activity. ACS infectious diseases 7 (6) (2021)
Shaobo Jin, Xueyong Wei, Juan Ren, Zhuangde Jiang, Chris Abell, Ziyi Yu
Construction of core-shell microcapsules via focused surface acoustic wave microfluidics. Lab on a chip 20 (17) (2020)
Zhi-Jun Meng, Ji Liu, Ziyi Yu, Hantao Zhou, Xu Deng, Chris Abell, Oren A Scherman
Viscoelastic Hydrogel Microfibers Exploiting Cucurbit[8]uril Host-Guest Chemistry and Microfluidics. ACS applied materials & interfaces 12 (15) (2020)
Mohamad Sabbah, Vitor Mendes, Robert G Vistal, David M G Dias, Monika Záhorszká, Katarína Mikušová, Jana Korduláková, Anthony G Coyne, Tom L Blundell, Chris Abell
Fragment-Based Design of Mycobacterium tuberculosis InhA Inhibitors. Journal of medicinal chemistry 63 (9) (2020)
João A Ribeiro, Alexander Hammer, Gerardo Andrés Libreros-Zúñiga, Sair M Chavez-Pacheco, Petros Tyrakis, Gabriel S de Oliveira, Timothy Kirkman, Jamal El Bakali, Silvana A Rocco, Mauricio L Sforça, Roberto Parise-Filho, Anthony G Coyne, Tom L Blundell, Chris Abell, Marcio Vinicius Bertacine Dias
Using a Fragment-Based Approach to Identify Alternative Chemical Scaffolds Targeting Dihydrofolate Reductase from Mycobacterium tuberculosis. ACS infectious diseases 6 (8) (2020)
Alejandro Méndez-Ardoy, Alfonso Bayón-Fernández, Ziyi Yu, Chris Abell, Juan R Granja, Javier Montenegro
Spatially Controlled Supramolecular Polymerization of Peptide Nanotubes by Microfluidics. Angewandte Chemie (International ed. in English) 59 (17) (2020)
Mohamad Sabbah, Vitor Mendes, Robert G Vistal, David M G Dias, Monika Záhorszká, Katarína Mikušová, Jana Korduláková, Anthony G Coyne, Tom L Blundell, Chris Abell
Correction to Fragment-Based Design of Mycobacterium tuberculosis InhA Inhibitors. Journal of medicinal chemistry 63 (15) (2020)
Andrew J Whitehouse, Sherine E Thomas, Karen P Brown, Alexander Fanourakis, Daniel S-H Chan, M Daben J Libardo, Vitor Mendes, Helena I M Boshoff, R Andres Floto, Chris Abell, Tom L Blundell, Anthony G Coyne
Development of Inhibitors against Mycobacterium abscessus tRNA (m1G37) Methyltransferase (TrmD) Using Fragment-Based Approaches. Journal of medicinal chemistry 62 (15) (2019)
Benoît Bestgen, Isabelle Krimm, Irina Kufareva, Ahmed Ashraf Moustafa Kamal, Wei-Guang Seetoh, Chris Abell, Rolf Wolfgang Hartmann, Ruben Abagyan, Claude Cochet, Marc Le Borgne, Matthias Engel, Thierry Lomberget
2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 1. Identification of an Allosteric Binding Site. Journal of medicinal chemistry 62 (4) (2019)
Benoît Bestgen, Irina Kufareva, Wei-Guang Seetoh, Chris Abell, Rolf Wolfgang Hartmann, Ruben Abagyan, Marc Le Borgne, Odile Filhol-Cochet, Claude Cochet, Thierry Lomberget, Matthias Engel
2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 2. Structure-Based Optimization and Investigation of Effects Specific to the Allosteric Mode of Action. Journal of medicinal chemistry 62 (4) (2019)
Andrew J Whitehouse, M Daben J Libardo, Monica Kasbekar, Paul D Brear, Gerhard Fischer, Craig J Thomas, Clifton E Barry, Helena I M Boshoff, Anthony G Coyne, Chris Abell
Targeting of Fumarate Hydratase from Mycobacterium tuberculosis Using Allosteric Inhibitors with a Dimeric-Binding Mode. Journal of medicinal chemistry 62 (23) (2019)
Daniel Shiu-Hin Chan, Wei-Guang Seetoh, Brendan N McConnell, Dijana Matak-Vinković, Sherine E Thomas, Vitor Mendes, Michal Blaszczyk, Anthony G Coyne, Tom L Blundell, Chris Abell
Structural insights into the EthR-DNA interaction using native mass spectrometry. Chemical communications (Cambridge, England) 53 (25) (2018)
Ana Trapero, Angela Pacitto, Vinayak Singh, Mohamad Sabbah, Anthony G Coyne, Valerie Mizrahi, Tom L Blundell, David B Ascher, Chris Abell
Fragment-Based Approach to Targeting Inosine-5'-monophosphate Dehydrogenase (IMPDH) from Mycobacterium tuberculosis. Journal of medicinal chemistry 61 (7) (2018)
Sara Abalde-Cela, Patricia Taladriz-Blanco, Marcelo Ganzarolli de Oliveira, Chris Abell
Droplet microfluidics for the highly controlled synthesis of branched gold nanoparticles. Scientific reports 8 (1) (2018)
Ziyi Yu, Ji Liu, Cindy Soo Yun Tan, Oren A Scherman, Chris Abell
Supramolecular Nested Microbeads as Building Blocks for Macroscopic Self-Healing Scaffolds. Angewandte Chemie (International ed. in English) 57 (12) (2018)
Yang Lan, Alessio Caciagli, Giulia Guidetti, Ziyi Yu, Ji Liu, Villads Egede Johansen, Marlous Kamp, Chris Abell, Silvia Vignolini, Oren A Scherman, Erika Eiser
Unexpected stability of aqueous dispersions of raspberry-like colloids. Nature communications 9 (1) (2018)
Daniel S-H Chan, Madeline E Kavanagh, Kirsty J McLean, Andrew W Munro, Dijana Matak-Vinković, Anthony G Coyne, Chris Abell
Effect of DMSO on Protein Structure and Interactions Assessed by Collision-Induced Dissociation and Unfolding. Analytical chemistry 89 (18) (2017)
Petar O Nikiforov, Michal Blaszczyk, Sachin Surade, Helena I Boshoff, Andaleeb Sajid, Vincent Delorme, Nathalie Deboosere, Priscille Brodin, Alain R Baulard, Clifton E Barry, Tom L Blundell, Chris Abell
Fragment-Sized EthR Inhibitors Exhibit Exceptionally Strong Ethionamide Boosting Effect in Whole-Cell Mycobacterium tuberculosis Assays. ACS chemical biology 12 (5) (2017)
Daniel Shiu-Hin Chan, Vitor Mendes, Sherine E Thomas, Brendan N McConnell, Dijana Matak-Vinković, Anthony G Coyne, Tom L Blundell, Chris Abell
Fragment Screening against the EthR-DNA Interaction by Native Mass Spectrometry. Angewandte Chemie (International ed. in English) 56 (26) (2017)
Madeline E Kavanagh, Jude Chenge, Azedine Zoufir, Kirsty J McLean, Anthony G Coyne, Andreas Bender, Andrew W Munro, Chris Abell
Fragment Profiling Approach to Inhibitors of the Orphan M. tuberculosis P450 CYP144A1. Biochemistry 56 (11) (2017)