Michael O Hottiger (Michael Hottiger)

ResearcherID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 31

Top Venues

EMBO reports

Nature communications

Biomedicines

Journal of proteome research

University of Zurich

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Zurich

Switzerland

Head of Department :: Department of Molecular Mechanisms of Disease

Publications

Simon D Schwarz, Jianming Xu, Kapila Gunasekera, David Schürmann, Cathrine B Vågbø, Elena Ferrari, Geir Slupphaug, Michael O Hottiger, Primo Schär, Roland Steinacher
Covalent PARylation of DNA base excision repair proteins regulates DNA demethylation. Nature communications 15 (1) (2024)
Meneka Rupasinghe, Cristiana Bersaglieri, Deena M Leslie Pedrioli, Patrick G A Pedrioli, Martina Panatta, Michael O Hottiger, Paolo Cinelli, Raffaella Santoro
PRAMEL7 and CUL2 decrease NuRD stability to establish ground-state pluripotency. EMBO reports (2024)
Flurina Böhi, Michael O Hottiger
Expanding the Perspective on PARP1 and Its Inhibitors in Cancer Therapy: From DNA Damage Repair to Immunomodulation. Biomedicines 12 (7) (2024)
Flurina Böhi, Michael O Hottiger
Expanding the Perspective on PARP1 and Its Inhibitors in Cancer Therapy: From DNA Damage Repair to Immunomodulation. Biomedicines 12 (7) (2024)
Simon D Schwarz, Jianming Xu, Kapila Gunasekera, David Schürmann, Cathrine B Vågbø, Elena Ferrari, Geir Slupphaug, Michael O Hottiger, Primo Schär, Roland Steinacher
Covalent PARylation of DNA base excision repair proteins regulates DNA demethylation. Nature communications 15 (1) (2024)
Meneka Rupasinghe, Cristiana Bersaglieri, Deena M Leslie Pedrioli, Patrick G A Pedrioli, Martina Panatta, Michael O Hottiger, Paolo Cinelli, Raffaella Santoro
PRAMEL7 and CUL2 decrease NuRD stability to establish ground-state pluripotency. EMBO reports 25 (3) (2024)
Meneka Rupasinghe, Cristiana Bersaglieri, Deena M Leslie Pedrioli, Patrick G A Pedrioli, Martina Panatta, Michael O Hottiger, Paolo Cinelli, Raffaella Santoro
PRAMEL7 and CUL2 decrease NuRD stability to establish ground-state pluripotency. EMBO reports 25 (3) (2024)
Flurina Böhi, Michael O Hottiger
Expanding the Perspective on PARP1 and Its Inhibitors in Cancer Therapy: From DNA Damage Repair to Immunomodulation. Biomedicines 12 (7) (2024)
Meneka Rupasinghe, Cristiana Bersaglieri, Deena M Leslie Pedrioli, Patrick G A Pedrioli, Martina Panatta, Michael O Hottiger, Paolo Cinelli, Raffaella Santoro
PRAMEL7 and CUL2 decrease NuRD stability to establish ground-state pluripotency. EMBO reports 25 (3) (2024)
Meneka Rupasinghe, Cristiana Bersaglieri, Deena M Leslie Pedrioli, Patrick G A Pedrioli, Martina Panatta, Michael O Hottiger, Paolo Cinelli, Raffaella Santoro
PRAMEL7 and CUL2 decrease NuRD stability to establish ground-state pluripotency. EMBO reports (2024)
Simon D Schwarz, Jianming Xu, Kapila Gunasekera, David Schürmann, Cathrine B Vågbø, Elena Ferrari, Geir Slupphaug, Michael O Hottiger, Primo Schär, Roland Steinacher
Covalent PARylation of DNA base excision repair proteins regulates DNA demethylation. Nature communications 15 (1) (2024)
Anka Güldenpfennig, Ann-Katrin Hopp, Lukas Muskalla, Patrick Manetsch, Fabio Raith, Lars Hellweg, Cyril Dördelmann, Deena M Leslie Pedrioli, Kai Johnsson, Giulio Superti-Furga, Michael O Hottiger
Absence of mitochondrial SLC25A51 enhances PARP1-dependent DNA repair by increasing nuclear NAD+ levels. Nucleic acids research (2023)
Tatiana Kamaletdinova, Wen Zong, Pavel Urbánek, Sijia Wang, Mara Sannai, Paulius Grigaravičius, Wenli Sun, Zahra Fanaei-Kahrani, Aswin Mangerich, Michael O Hottiger, Tang-Liang Li, Zhao-Qi Wang
Poly(ADP-Ribose) Polymerase-1 Lacking Enzymatic Activity Is Not Compatible with Mouse Development. Cells 12 (16) (2023)
Peter Schraml, Fabio Aimi, Martin Zoche, Domingo Aguilera-Garcia, Fabian Arnold, Holger Moch, Michael O Hottiger
Altered cytoplasmic and nuclear ADP-ribosylation levels analyzed with an improved ADP-ribose binder are a prognostic factor in renal cell carcinoma. The journal of pathology. Clinical research (2023)
Patrick Manetsch, Flurina Böhi, Kathrin Nowak, Deena M Leslie Pedrioli, Michael O Hottiger
PARP7-mediated ADP-ribosylation of FRA1 promotes cancer cell growth by repressing IRF1- and IRF3-dependent apoptosis. Proceedings of the National Academy of Sciences of the United States of America 120 (49) (2023)
Lorenza P Ferretti, Flurina Böhi, Deena M Leslie Pedrioli, Phil Fang Cheng, Elena Ferrari, Petra Baumgaertner, Abdiel Alvarado-Diaz, Federica Sella, Alessandra Cereghetti, Patrick Turko, Roni H G Wright, Katrien De Bock, Daniel E Speiser, Roberto Ferrari, Mitchell Paul Levesque, Michael O Hottiger
Combinatorial treatment with PARP and MAPK inhibitors overcomes phenotype switch-driven drug resistance in advanced melanoma. Cancer research (2023)
Lin Liu, Jarrod John Sandow, Deena M Leslie Pedrioli, André L Samson, Natasha Silke, Tobias Kratina, Rebecca L Ambrose, Marcel Doerflinger, Zhaoqing Hu, Emma Morrish, Diep Chau, Andrew J Kueh, Cheree Fitzibbon, Marc Pellegrini, Jaclyn S Pearson, Michael O Hottiger, Andrew Ian Webb, Najoua Lalaoui, John Silke
Tankyrase-mediated ADP-ribosylation is a regulator of TNF-induced death. Science advances 8 (19) (2022)
Stephanie C Lüthi, Anna Howald, Kathrin Nowak, Robert Graage, Giody Bartolomei, Christine Neupert, Xaver Sidler, Deena M Leslie Pedrioli, Michael O Hottiger
Establishment of a Mass-Spectrometry-Based Method for the Identification of the In Vivo Whole Blood and Plasma ADP-Ribosylomes. Journal of proteome research 20 (6) (2021)
Flurina Boehi, Patrick Manetsch, Michael O Hottiger
Interplay between ADP-ribosyltransferases and essential cell signaling pathways controls cellular responses. Cell discovery 7 (1) (2021)
Fabio Aimi, Holger Moch, Peter Schraml, Michael O Hottiger
Cytoplasmic ADP-ribosylation levels correlate with markers of patient outcome in distinct human cancers. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 34 (8) (2021)
Ann-Katrin Hopp, Michael O Hottiger
Uncovering the Invisible: Mono-ADP-ribosylation Moved into the Spotlight. Cells 10 (3) (2021)
Kathrin Nowak, Florian Rosenthal, Tobias Karlberg, Mareike Bütepage, Ann-Gerd Thorsell, Birgit Dreier, Jonas Grossmann, Jens Sobek, Ralph Imhof, Bernhard Lüscher, Herwig Schüler, Andreas Plückthun, Deena M Leslie Pedrioli, Michael O Hottiger
Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins. Nature communications 11 (1) (2020)
Yashwanth Ashok, Moona Miettinen, Danilo Kimio Hirabae de Oliveira, Mahlet Z Tamirat, Katja Näreoja, Avlokita Tiwari, Michael O Hottiger, Mark S Johnson, Lari Lehtiö, Arto T Pulliainen
Discovery of Compounds Inhibiting the ADP-Ribosyltransferase Activity of Pertussis Toxin. ACS infectious diseases 6 (4) (2020)
Zhuan Zhou, Furong Huang, Indira Shrivastava, Rui Zhu, Aiping Luo, Michael O Hottiger, Ivet Bahar, Zhihua Liu, Massimo Cristofanilli, Yong Wan
New insight into the significance of KLF4 PARylation in genome stability, carcinogenesis, and therapy. EMBO molecular medicine 12 (12) (2020)
Peter M Gehrig, Kathrin Nowak, Christian Panse, Mario Leutert, Jonas Grossmann, Ralph Schlapbach, Michael O Hottiger
Gas-Phase Fragmentation of ADP-Ribosylated Peptides: Arginine-Specific Side-Chain Losses and Their Implication in Database Searches. Journal of the American Society for Mass Spectrometry 32 (1) (2020)
Hideyuki Higashi, Takashi Maejima, Lang Ho Lee, Yukiyoshi Yamazaki, Michael O Hottiger, Sasha A Singh, Masanori Aikawa
A Study into the ADP-Ribosylome of IFN-γ-Stimulated THP-1 Human Macrophage-like Cells Identifies ARTD8/PARP14 and ARTD9/PARP9 ADP-Ribosylation. Journal of proteome research 18 (4) (2019)
Friedrich A Kunze, Michael Bauer, Juliana Komuczki, Margit Lanzinger, Kapila Gunasekera, Ann-Katrin Hopp, Mareike Lehmann, Burkhard Becher, Anne Müller, Michael O Hottiger
ARTD1 in Myeloid Cells Controls the IL-12/18-IFN-γ Axis in a Model of Sterile Sepsis, Chronic Bacterial Infection, and Cancer. Journal of immunology (Baltimore, Md. : 1950) 202 (5) (2019)
Sonia Tugues, Ana Amorim, Sabine Spath, Guillaume Martin-Blondel, Bettina Schreiner, Donatella De Feo, Mirjam Lutz, Franco Guscetti, Petya Apostolova, Claudia Haftmann, Peter Hasselblatt, Nicolas G Núñez, Michael O Hottiger, Maries van den Broek, Markus Gabriel Manz, Robert Zeiser, Burkhard Becher
Graft-versus-host disease, but not graft-versus-leukemia immunity, is mediated by GM-CSF-licensed myeloid cells. Science translational medicine 10 (469) (2019)
Deena M Leslie Pedrioli, Mario Leutert, Vera Bilan, Kathrin Nowak, Kapila Gunasekera, Elena Ferrari, Ralph Imhof, Lars Malmström, Michael O Hottiger
Comprehensive ADP-ribosylome analysis identifies tyrosine as an ADP-ribose acceptor site. EMBO reports 19 (8) (2018)
Jeannette Abplanalp, Mario Leutert, Emilie Frugier, Kathrin Nowak, Roxane Feurer, Jiro Kato, Hans V A Kistemaker, Dmitri V Filippov, Joel Moss, Amedeo Caflisch, Michael O Hottiger
Proteomic analyses identify ARH3 as a serine mono-ADP-ribosylhydrolase. Nature communications 8 (1) (2017)
Vera Bilan, Mario Leutert, Paolo Nanni, Christian Panse, Michael O Hottiger
Combining Higher-Energy Collision Dissociation and Electron-Transfer/Higher-Energy Collision Dissociation Fragmentation in a Product-Dependent Manner Confidently Assigns Proteomewide ADP-Ribose Acceptor Sites. Analytical chemistry 89 (3) (2017)

Michael O Hottiger.css-eqlu8i{font-size:small;padding-left:4px;} (Michael Hottiger)

Publication Activity (10 Years)

Top Topics

Top Venues

Michael O Hottiger (Michael Hottiger)