Ivan Ahel

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 48

Top Venues

Nature structural & molecular biology

Nature communications

The EMBO journal

Nucleic acids research

University of Oxford

University of Zagreb (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Oxford Oct 01 2013

United Kingdom

Group Leader :: Sir William Dunn School of Pathology

Education History

University of Zagreb

Croatia

PHD

Publications

Bara Cihlova, Yang Lu, Andreja Mikoč, Marion Schuller, Ivan Ahel
Specificity of DNA ADP-Ribosylation Reversal by NADARs. Toxins 16 (5) (2024)
Anne R Wondisford, Junyeop Lee, Robert Lu, Marion Schuller, Joséphine Groslambert, Ragini Bhargava, Sandra Schamus-Haynes, Leyneir C Cespedes, Patricia L Opresko, Hilda A Pickett, Jaewon Min, Ivan Ahel, Roderick J O'Sullivan
Deregulated DNA ADP-ribosylation impairs telomere replication. Nature structural & molecular biology 31 (5) (2024)
Pulak Kar, Chatrin Chatrin, Nina Đukić, Osamu Suyari, Marion Schuller, Kang Zhu, Evgeniia Prokhorova, Nicolas Bigot, Juraj Ahel, Jonas Damgaard Elsborg, Michael L Nielsen, Tim Clausen, Sébastien Huet, Mario Niepel, Sumana Sanyal, Dragana Ahel, Rebecca Smith, Ivan Ahel
PARP14 and PARP9/DTX3L regulate interferon-induced ADP-ribosylation. The EMBO journal 43 (14) (2024)
Anne R Wondisford, Junyeop Lee, Robert Lu, Marion Schuller, Joséphine Groslambert, Ragini Bhargava, Sandra Schamus-Haynes, Leyneir C Cespedes, Patricia L Opresko, Hilda A Pickett, Jaewon Min, Ivan Ahel, Roderick J O'Sullivan
Deregulated DNA ADP-ribosylation impairs telomere replication. Nature structural & molecular biology (2024)
Pulak Kar, Chatrin Chatrin, Nina Đukić, Osamu Suyari, Marion Schuller, Kang Zhu, Evgeniia Prokhorova, Nicolas Bigot, Juraj Ahel, Jonas Damgaard Elsborg, Michael L Nielsen, Tim Clausen, Sébastien Huet, Mario Niepel, Sumana Sanyal, Dragana Ahel, Rebecca Smith, Ivan Ahel
PARP14 and PARP9/DTX3L regulate interferon-induced ADP-ribosylation. The EMBO journal (2024)
Pulak Kar, Chatrin Chatrin, Nina Đukić, Osamu Suyari, Marion Schuller, Kang Zhu, Evgeniia Prokhorova, Nicolas Bigot, Juraj Ahel, Jonas Damgaard Elsborg, Michael L Nielsen, Tim Clausen, Sébastien Huet, Mario Niepel, Sumana Sanyal, Dragana Ahel, Rebecca Smith, Ivan Ahel
PARP14 and PARP9/DTX3L regulate interferon-induced ADP-ribosylation. The EMBO journal 43 (14) (2024)
Zhengrui Zhang, Jiaqi Fu, Johannes Gregor Matthias Rack, Chuang Li, Jim Voorneveld, Dmitri V Filippov, Ivan Ahel, Zhao-Qing Luo, Chittaranjan Das
Legionella metaeffector MavL reverses ubiquitin ADP-ribosylation via a conserved arginine-specific macrodomain. Nature communications 15 (1) (2024)
Siham Zentout, Victor Imburchia, Catherine Chapuis, Lena Duma, Kira Schützenhofer, Evgeniia Prokhorova, Ivan Ahel, Rebecca Smith, Sébastien Huet
Histone ADP-ribosylation promotes resistance to PARP inhibitors by facilitating PARP1 release from DNA lesions. Proceedings of the National Academy of Sciences of the United States of America 121 (25) (2024)
Siham Zentout, Victor Imburchia, Catherine Chapuis, Lena Duma, Kira Schützenhofer, Evgeniia Prokhorova, Ivan Ahel, Rebecca Smith, Sébastien Huet
Histone ADP-ribosylation promotes resistance to PARP inhibitors by facilitating PARP1 release from DNA lesions. Proceedings of the National Academy of Sciences of the United States of America 121 (25) (2024)
Anne R Wondisford, Junyeop Lee, Robert Lu, Marion Schuller, Joséphine Groslambert, Ragini Bhargava, Sandra Schamus-Haynes, Leyneir C Cespedes, Patricia L Opresko, Hilda A Pickett, Jaewon Min, Ivan Ahel, Roderick J O'Sullivan
Deregulated DNA ADP-ribosylation impairs telomere replication. Nature structural & molecular biology 31 (5) (2024)
Zhengrui Zhang, Jiaqi Fu, Johannes Gregor Matthias Rack, Chuang Li, Jim Voorneveld, Dmitri V Filippov, Ivan Ahel, Zhao-Qing Luo, Chittaranjan Das
Legionella metaeffector MavL reverses ubiquitin ADP-ribosylation via a conserved arginine-specific macrodomain. Nature communications 15 (1) (2024)
Pulak Kar, Chatrin Chatrin, Nina Đukić, Osamu Suyari, Marion Schuller, Kang Zhu, Evgeniia Prokhorova, Nicolas Bigot, Juraj Ahel, Jonas Damgaard Elsborg, Michael L Nielsen, Tim Clausen, Sébastien Huet, Mario Niepel, Sumana Sanyal, Dragana Ahel, Rebecca Smith, Ivan Ahel
PARP14 and PARP9/DTX3L regulate interferon-induced ADP-ribosylation. The EMBO journal 43 (14) (2024)
Zhengrui Zhang, Jiaqi Fu, Johannes Gregor Matthias Rack, Chuang Li, Jim Voorneveld, Dmitri V Filippov, Ivan Ahel, Zhao-Qing Luo, Chittaranjan Das
Legionella metaeffector MavL reverses ubiquitin ADP-ribosylation via a conserved arginine-specific macrodomain. Nature communications 15 (1) (2024)
Siham Zentout, Victor Imburchia, Catherine Chapuis, Lena Duma, Kira Schützenhofer, Evgeniia Prokhorova, Ivan Ahel, Rebecca Smith, Sébastien Huet
Histone ADP-ribosylation promotes resistance to PARP inhibitors by facilitating PARP1 release from DNA lesions. Proceedings of the National Academy of Sciences of the United States of America 121 (25) (2024)
Pulak Kar, Chatrin Chatrin, Nina Đukić, Osamu Suyari, Marion Schuller, Kang Zhu, Evgeniia Prokhorova, Nicolas Bigot, Juraj Ahel, Jonas Damgaard Elsborg, Michael L Nielsen, Tim Clausen, Sébastien Huet, Mario Niepel, Sumana Sanyal, Dragana Ahel, Rebecca Smith, Ivan Ahel
PARP14 and PARP9/DTX3L regulate interferon-induced ADP-ribosylation. The EMBO journal 43 (14) (2024)
Bara Cihlova, Yang Lu, Andreja Mikoč, Marion Schuller, Ivan Ahel
Specificity of DNA ADP-Ribosylation Reversal by NADARs. Toxins 16 (5) (2024)
Zhengrui Zhang, Jiaqi Fu, Johannes Gregor Matthias Rack, Chuang Li, Jim Voorneveld, Dmitri V Filippov, Ivan Ahel, Zhao-Qing Luo, Chittaranjan Das
Legionella metaeffector MavL reverses ubiquitin ADP-ribosylation via a conserved arginine-specific macrodomain. Nature communications 15 (1) (2024)
Bara Cihlova, Yang Lu, Andreja Mikoč, Marion Schuller, Ivan Ahel
Specificity of DNA ADP-Ribosylation Reversal by NADARs. Toxins 16 (5) (2024)
Kang Zhu, Chatrin Chatrin, Marcin Józef Suskiewicz, Vincent Aucagne, Benjamin M Foster, Benedikt Mathias Kessler, Ian Gibbs-Seymour, Dragana Ahel, Ivan Ahel
Ubiquitylation of nucleic acids by DELTEX ubiquitin E3 ligase DTX3L. EMBO reports (2024)
Anne R Wondisford, Junyeop Lee, Robert Lu, Marion Schuller, Joséphine Groslambert, Ragini Bhargava, Sandra Schamus-Haynes, Leyneir C Cespedes, Patricia L Opresko, Hilda A Pickett, Jaewon Min, Ivan Ahel, Roderick J O'Sullivan
Deregulated DNA ADP-ribosylation impairs telomere replication. Nature structural & molecular biology (2024)
Anne R Wondisford, Junyeop Lee, Robert Lu, Marion Schuller, Joséphine Groslambert, Ragini Bhargava, Sandra Schamus-Haynes, Leyneir C Cespedes, Patricia L Opresko, Hilda A Pickett, Jaewon Min, Ivan Ahel, Roderick J O'Sullivan
Deregulated DNA ADP-ribosylation impairs telomere replication. Nature structural & molecular biology 31 (5) (2024)
Rebecca Smith, Siham Zentout, Magdalena Rother, Nicolas Bigot, Catherine Chapuis, Alexandra Mihuț, Florian Franz Zobel, Ivan Ahel, Haico van Attikum, Gyula Timinszky, Sébastien Huet
HPF1-dependent histone ADP-ribosylation triggers chromatin relaxation to promote the recruitment of repair factors at sites of DNA damage. Nature structural & molecular biology (2023)
Rebecca Smith, Siham Zentout, Magdalena Rother, Nicolas Bigot, Catherine Chapuis, Alexandra Mihuț, Florian Franz Zobel, Ivan Ahel, Haico van Attikum, Gyula Timinszky, Sébastien Huet
HPF1-dependent histone ADP-ribosylation triggers chromatin relaxation to promote the recruitment of repair factors at sites of DNA damage. Nature structural & molecular biology 30 (5) (2023)
Marcin Józef Suskiewicz, Deeksha Munnur, Øyvind Strømland, Ji-Chun Yang, Laura E Easton, Chatrin Chatrin, Kang Zhu, Domagoj Baretić, Stéphane Goffinont, Marion Schuller, Wing-Fung Wu, Jonathan M Elkins, Dragana Ahel, Sumana Sanyal, David Neuhaus, Ivan Ahel
Updated protein domain annotation of the PARP protein family sheds new light on biological function. Nucleic acids research (2023)
Rebecca Smith, Siham Zentout, Magdalena Rother, Nicolas Bigot, Catherine Chapuis, Alexandra Mihuț, Florian Franz Zobel, Ivan Ahel, Haico van Attikum, Gyula Timinszky, Sébastien Huet
HPF1-dependent histone ADP-ribosylation triggers chromatin relaxation to promote the recruitment of repair factors at sites of DNA damage. Nature structural & molecular biology 30 (5) (2023)
Rebecca Smith, Siham Zentout, Magdalena Rother, Nicolas Bigot, Catherine Chapuis, Alexandra Mihuț, Florian Franz Zobel, Ivan Ahel, Haico van Attikum, Gyula Timinszky, Sébastien Huet
HPF1-dependent histone ADP-ribosylation triggers chromatin relaxation to promote the recruitment of repair factors at sites of DNA damage. Nature structural & molecular biology (2023)
Lena Duma, Ivan Ahel
The function and regulation of ADP-ribosylation in the DNA damage response. Biochemical Society transactions (2023)
Kang Zhu, Marcin Józef Suskiewicz, Chatrin Chatrin, Øyvind Strømland, Bryan W Dorsey, Vincent Aucagne, Dragana Ahel, Ivan Ahel
DELTEX E3 ligases ubiquitylate ADP-ribosyl modification on nucleic acids. Nucleic acids research (2023)
Rebecca Smith, Siham Zentout, Magdalena Rother, Nicolas Bigot, Catherine Chapuis, Alexandra Mihuț, Florian Franz Zobel, Ivan Ahel, Haico van Attikum, Gyula Timinszky, Sébastien Huet
HPF1-dependent histone ADP-ribosylation triggers chromatin relaxation to promote the recruitment of repair factors at sites of DNA damage. Nature structural & molecular biology 30 (5) (2023)
Nina Đukić, Øyvind Strømland, Jonas Damgaard Elsborg, Deeksha Munnur, Kang Zhu, Marion Schuller, Chatrin Chatrin, Pulak Kar, Lena Duma, Osamu Suyari, Johannes Gregor Matthias Rack, Domagoj Baretić, Dorian Richard Kenneth Crudgington, Joséphine Groslambert, Gerissa Fowler, Sven Wijngaarden, Evgeniia A Prokhorova, Jan Rehwinkel, Herwig Schüler, Dmitri V Filippov, Sumana Sanyal, Dragana Ahel, Michael Lund Nielsen, Rebecca Smith, Ivan Ahel
PARP14 is a PARP with both ADP-ribosyl transferase and hydrolase activities. Science advances 9 (37) (2023)
Pietro Fontana, Sara C Buch-Larsen, Osamu Suyari, Rebecca Smith, Marcin Józef Suskiewicz, Kira Schützenhofer, Antonio Ariza, Johannes Gregor Matthias Rack, Michael Lund Nielsen, Ivan Ahel
Serine ADP-ribosylation in Drosophila provides insights into the evolution of reversible ADP-ribosylation signalling. Nature communications 14 (1) (2023)
Marion Schuller, Ivan Ahel
Beyond protein modification: the rise of non-canonical ADP-ribosylation. The Biochemical journal 479 (4) (2022)
Kang Zhu, Marcin Józef Suskiewicz, Andrea Hloušek-Kasun, Hervé Meudal, Andreja Mikoč, Vincent Aucagne, Dragana Ahel, Ivan Ahel
DELTEX E3 ligases ubiquitylate ADP-ribosyl modification on protein substrates. Science advances 8 (40) (2022)
Thorsten Mosler, H Irem Baymaz, Justus F Gräf, Ivan Mikicic, Georges Blattner, Edward Bartlett, Matthias Ostermaier, Rossana Piccinno, Jiwen Yang, Andrea Voigt, Marco Gatti, Stefania Pellegrino, Matthias Altmeyer, Katja Luck, Ivan Ahel, Vassilis Roukos, Petra Beli
PARP1 proximity proteomics reveals interaction partners at stressed replication forks. Nucleic acids research 50 (20) (2022)
Stefan Gahbauer, Galen J Correy, Marion Schuller, Matteo P Ferla, Yagmur Umay Doruk, Moira M Rachman, Taiasean Wu, Morgan E Diolati, Siyi Wang, R Jeffrey Neitz, Daren Fearon, Dmytro S Radchenko, Yurii S Moroz, John J Irwin, Adam R Renslo, Jenny C Taylor, Jason E Gestwicki, Frank von Delft, Alan Ashworth, Ivan Ahel, Brian K Shoichet, Brian K Shoichet
Structure-based inhibitor optimization for the Nsp3 Macrodomain of SARS-CoV-2. bioRxiv : the preprint server for biology (2022)
Danique Beijer, Thomas Agnew, Johannes Gregor Matthias Rack, Evgeniia A Prokhorova, Tine Deconinck, Berten Ceulemans, Stojan Peric, Vedrana Milic Rasic, Peter De Jonghe, Ivan Ahel, Jonathan Baets
Biallelic ADPRHL2 mutations in complex neuropathy affect ADP ribosylation and DNA damage response. Life science alliance 4 (11) (2021)
Ivo A Hendriks, Sara C Buch-Larsen, Evgeniia A Prokhorova, Jonas Damgaard Elsborg, Alexandra K L F S Rebak, Kang Zhu, Dragana Ahel, Claudia Lukas, Ivan Ahel, Michael Lund Nielsen
The regulatory landscape of the human HPF1- and ARH3-dependent ADP-ribosylome. Nature communications 12 (1) (2021)
Marion Schuller, Rachel E Butler, Antonio Ariza, Callum Tromans-Coia, Gytis Jankevicius, Timothy D W Claridge, Sharon L Kendall, Shan Goh, Graham R Stewart, Ivan Ahel
Molecular basis for DarT ADP-ribosylation of a DNA base. Nature 596 (7873) (2021)
Evgeniia A Prokhorova, Florian Zobel, Rebecca Smith, Siham Zentout, Ian Gibbs-Seymour, Kira Schützenhofer, Alessandra Peters, Joséphine Groslambert, Valentina Zorzini, Thomas Agnew, John Brognard, Michael Lund Nielsen, Dragana Ahel, Sébastien Huet, Marcin Józef Suskiewicz, Ivan Ahel
Serine-linked PARP1 auto-modification controls PARP inhibitor response. Nature communications 12 (1) (2021)
Callum Tromans-Coia, Andrea Sanchi, Giuliana K Moeller, Gyula Timinszky, Massimo Lopes, Ivan Ahel
TARG1 protects against toxic DNA ADP-ribosylation. Nucleic acids research 49 (18) (2021)
Johannes Gregor Matthias Rack, Qiang Liu, Valentina Zorzini, Jim Voorneveld, Antonio Ariza, Kourosh Honarmand Ebrahimi, Julia M Reber, Sarah C Krassnig, Dragana Ahel, Gijsbert A van der Marel, Aswin Mangerich, James S O McCullagh, Dmitri V Filippov, Ivan Ahel
Mechanistic insights into the three steps of poly(ADP-ribosylation) reversal. Nature communications 12 (1) (2021)
Bernhard Lüscher, Ivan Ahel, Matthias Altmeyer, Alan Ashworth, Peter Bai, Paul Chang, Michael Cohen, Daniela Corda, Françoise Dantzer, Matthew D Daugherty, Ted M Dawson, Valina L Dawson, Sebastian Deindl, Anthony R Fehr, Karla L H Feijs, Dmitri V Filippov, Jean-Philippe Gagné, Giovanna Grimaldi, Sebastian Guettler, Nicolas C Hoch, Michael O Hottiger, Patricia Korn, W Lee Kraus, Andreas Ladurner, Lari Lehtiö, Anthony K L Leung, Christopher J Lord, Aswin Mangerich, Ivan Matic, Jason Matthews, George-Lucian Moldovan, Joel Moss, Gioacchino Natoli, Michael L Nielsen, Mario Niepel, Friedrich Nolte, John Pascal, Bryce M Paschal, Krzysztof Pawłowski, Guy G Poirier, Susan Smith, Gyula Timinszky, Zhao-Qi Wang, José Yélamos, Xiaochun Yu, Roko Zaja, Mathias Ziegler
ADP-ribosyltransferases, an update on function and nomenclature. The FEBS journal (2021)
Marion Schuller, Galen J Correy, Stefan Gahbauer, Daren Fearon, Taiasean Wu, Roberto Efraín Díaz, Iris D Young, Luan Carvalho Martins, Dominique H Smith, Ursula Schulze-Gahmen, Tristan W Owens, Ishan Deshpande, Gregory E Merz, Aye C Thwin, Justin T Biel, Jessica K Peters, Michelle Moritz, Nadia Herrera, Huong T Kratochvil, null null, Anthony Aimon, James M Bennett, José Brandão-Neto, Aina E Cohen, Alexandre Dias, Alice Douangamath, Louise Dunnett, Oleg Fedorov, Matteo P Ferla, Martin R Fuchs, Tyler J Gorrie-Stone, James M Holton, Michael G Johnson, Tobias Krojer, George Meigs, Ailsa J Powell, Johannes Gregor Matthias Rack, Victor L Rangel, Silvia Russi, Rachael E Skyner, Clyde A Smith, Alexei S Soares, Jennifer L Wierman, Kang Zhu, Peter O'Brien, Natalia Jura, Alan Ashworth, John J Irwin, Michael C Thompson, Jason E Gestwicki, Frank von Delft, Brian K Shoichet, Brian K Shoichet, Ivan Ahel
Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking. Science advances 7 (16) (2021)
Marcin Józef Suskiewicz, Luca Palazzo, Rebecca Hughes, Ivan Ahel
Progress and outlook in studying the substrate specificities of PARPs and related enzymes. The FEBS journal 288 (7) (2020)
Luca Palazzo, Orsolya Leidecker, Evgeniia A Prokhorova, Helen Dauben, Ivan Matic, Ivan Ahel
Serine is the major residue for ADP-ribosylation upon DNA damage. eLife 7 (2018)
Luca Palazzo, Ivan Ahel
PARPs in genome stability and signal transduction: implications for cancer therapy. Biochemical Society transactions 46 (6) (2018)
Pietro Fontana, Juan Jose Bonfiglio, Luca Palazzo, Edward Bartlett, Ivan Matic, Ivan Ahel
Serine ADP-ribosylation reversal by the hydrolase ARH3. eLife 6 (2017)
Alasdair R Gunn, Benito Banos-Pinero, Peggy Paschke, Luis Sanchez-Pulido, Antonio Ariza, Joseph Day, Mehera Emrich, David Leys, Chris P Ponting, Ivan Ahel, Nicholas D Lakin
The role of ADP-ribosylation in regulating DNA interstrand crosslink repair. Journal of cell science 129 (20) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Ivan Ahel