Caroline Sychterz

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 6

Top Topics

Molecular Dynamics

Machine Learning

Top Venues

CPT: pharmacometrics & systems pharmacology

Clinical pharmacology and therapeutics

Biopharmaceutics & drug disposition

International journal of molecular sciences

This page only lists publications with an associated author ORCID identifier.

Publications

Caroline Sychterz, Hong Shen, Yueping Zhang, Michael Sinz, Amin Rostami-Hodjegan, Brian James Schmidt, Lu Gaohua, Aleksandra Galetin
A close examination of BCRP's role in lactation and methods for predicting drug distribution into milk. CPT: pharmacometrics & systems pharmacology (2024)
Lu Gaohua, Mian Zhang, Caroline Sychterz, Ming Chang, Brian James Schmidt
The Interplay of Permeability, Metabolism, Transporters, and Dosing in Determining the Dynamics of the Tissue/Plasma Partition Coefficient and Volume of Distribution-A Theoretical Investigation Using Permeability-Limited, Physiologically Based Pharmacokinetic Modeling. International journal of molecular sciences 24 (22) (2023)
Manting Chiang, Caroline Sychterz, Vidya Perera, Samira Merali, Maria Palmisano, Ian E Templeton, Lu Gaohua
Physiologically Based Pharmacokinetic Modeling and Simulation of Mavacamten Exposure with Drug-Drug Interactions from CYP Inducers and Inhibitors by CYP2C19 Phenotype. Clinical pharmacology and therapeutics (2023)
Mian Zhang, Caroline Sychterz, Ming Chang, Lu Huang, Brian J Schmidt, Lu Gaohua
A perspective on the current use of the phase distribution model for predicting milk-to-plasma drug concentration ratio. CPT: pharmacometrics & systems pharmacology (2022)
Caroline Sychterz, Iain Gardner, Manting Chiang, Ramakrishna Rachumallu, Sibylle Neuhoff, Vidya Perera, Samira Merali, Brian J Schmidt, Lu Gaohua
Performance Verification of CYP2C19 Enzyme Abundance Polymorphism Settings within the Simcyp Simulator v21. Metabolites 12 (10) (2022)
Caroline Sychterz, Aleksandra Galetin, Kunal S Taskar
When special populations intersect with drug-drug interactions: Application of physiologically-based pharmacokinetic modeling in pregnant populations. Biopharmaceutics & drug disposition 42 (4) (2021)