Adam J Mead (A J Mead, Adam Mead)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 68

Top Topics

Acute Myeloid Leukemia

Tyrosine Kinase

Top Venues

British journal of haematology

Nature immunology

This page only lists publications with an associated author ORCID identifier.

Publications

Joana Carrelha, Stefania Mazzi, Axel Winroth, Michael Hagemann-Jensen, Christoph Ziegenhain, Kari Högstrand, Masafumi Seki, Margs S Brennan, Madeleine Lehander, Bishan Wu, Yiran Meng, Ellen Markljung, Ruggiero Norfo, Hisashi Ishida, Karin Belander Strålin, Francesca Grasso, Christina Simoglou Karali, Affaf Aliouat, Amy Hillen, Edwin Chari, Kimberly Siletti, Supat Thongjuea, Adam J Mead, Sten Linnarsson, Claus Nerlov, Rickard Sandberg, Tetsuichi Yoshizato, Petter S Woll, Sten Eirik W Jacobsen
Alternative platelet differentiation pathways initiated by nonhierarchically related hematopoietic stem cells. Nature immunology (2024)
Joana Carrelha, Stefania Mazzi, Axel Winroth, Michael Hagemann-Jensen, Christoph Ziegenhain, Kari Högstrand, Masafumi Seki, Margs S Brennan, Madeleine Lehander, Bishan Wu, Yiran Meng, Ellen Markljung, Ruggiero Norfo, Hisashi Ishida, Karin Belander Strålin, Francesca Grasso, Christina Simoglou Karali, Affaf Aliouat, Amy Hillen, Edwin Chari, Kimberly Siletti, Supat Thongjuea, Adam J Mead, Sten Linnarsson, Claus Nerlov, Rickard Sandberg, Tetsuichi Yoshizato, Petter S Woll, Sten Eirik W Jacobsen
Alternative platelet differentiation pathways initiated by nonhierarchically related hematopoietic stem cells. Nature immunology 25 (6) (2024)
Joana Carrelha, Stefania Mazzi, Axel Winroth, Michael Hagemann-Jensen, Christoph Ziegenhain, Kari Högstrand, Masafumi Seki, Margs S Brennan, Madeleine Lehander, Bishan Wu, Yiran Meng, Ellen Markljung, Ruggiero Norfo, Hisashi Ishida, Karin Belander Strålin, Francesca Grasso, Christina Simoglou Karali, Affaf Aliouat, Amy Hillen, Edwin Chari, Kimberly Siletti, Supat Thongjuea, Adam J Mead, Sten Linnarsson, Claus Nerlov, Rickard Sandberg, Tetsuichi Yoshizato, Petter S Woll, Sten Eirik W Jacobsen
Alternative platelet differentiation pathways initiated by nonhierarchically related hematopoietic stem cells. Nature immunology 25 (6) (2024)
Joana Carrelha, Stefania Mazzi, Axel Winroth, Michael Hagemann-Jensen, Christoph Ziegenhain, Kari Högstrand, Masafumi Seki, Margs S Brennan, Madeleine Lehander, Bishan Wu, Yiran Meng, Ellen Markljung, Ruggiero Norfo, Hisashi Ishida, Karin Belander Strålin, Francesca Grasso, Christina Simoglou Karali, Affaf Aliouat, Amy Hillen, Edwin Chari, Kimberly Siletti, Supat Thongjuea, Adam J Mead, Sten Linnarsson, Claus Nerlov, Rickard Sandberg, Tetsuichi Yoshizato, Petter S Woll, Sten Eirik W Jacobsen
Alternative platelet differentiation pathways initiated by nonhierarchically related hematopoietic stem cells. Nature immunology 25 (6) (2024)
Anna L Godfrey, Nikolaos Sousos, Rebecca Frewin, Mahesh Prahladan, Anna C Green, Andrew McGregor, Alesia Khan, Kate Milne, Faisal Amin, Elena Torre, Emma J Gudgin, Jonathan Lambert, Andrew James Wilson, Daniel Royston, Claire N Harrison, Adam J Mead
Clinical utility of investigations in triple-negative thrombocytosis: A real-world, multicentre evaluation of UK practice. British journal of haematology (2024)
Joana Carrelha, Stefania Mazzi, Axel Winroth, Michael Hagemann-Jensen, Christoph Ziegenhain, Kari Högstrand, Masafumi Seki, Margs S Brennan, Madeleine Lehander, Bishan Wu, Yiran Meng, Ellen Markljung, Ruggiero Norfo, Hisashi Ishida, Karin Belander Strålin, Francesca Grasso, Christina Simoglou Karali, Affaf Aliouat, Amy Hillen, Edwin Chari, Kimberly Siletti, Supat Thongjuea, Adam J Mead, Sten Linnarsson, Claus Nerlov, Rickard Sandberg, Tetsuichi Yoshizato, Petter S Woll, Sten Eirik W Jacobsen
Alternative platelet differentiation pathways initiated by nonhierarchically related hematopoietic stem cells. Nature immunology 25 (6) (2024)
Joana Carrelha, Stefania Mazzi, Axel Winroth, Michael Hagemann-Jensen, Christoph Ziegenhain, Kari Högstrand, Masafumi Seki, Margs S Brennan, Madeleine Lehander, Bishan Wu, Yiran Meng, Ellen Markljung, Ruggiero Norfo, Hisashi Ishida, Karin Belander Strålin, Francesca Grasso, Christina Simoglou Karali, Affaf Aliouat, Amy Hillen, Edwin Chari, Kimberly Siletti, Supat Thongjuea, Adam J Mead, Sten Linnarsson, Claus Nerlov, Rickard Sandberg, Tetsuichi Yoshizato, Petter S Woll, Sten Eirik W Jacobsen
Alternative platelet differentiation pathways initiated by nonhierarchically related hematopoietic stem cells. Nature immunology 25 (6) (2024)
Adam J de Smith, Joseph L Wiemels, Adam J Mead, Irene Roberts, Anindita Roy, Logan G Spector
Backtracking to the future: unraveling the origins of childhood leukemia. Leukemia 38 (2) (2023)
Claire N Harrison, Jyoti Nangalia, Rebecca Boucher, Aimee Jackson, Christina Yap, Jennifer O'Sullivan, Sonia Fox, Isaak Ailts, Amylou C Dueck, Holly L Geyer, Ruben A Mesa, William G Dunn, Eugene Nadezhdin, Natalia Curto-Garcia, Anna Green, Bridget Wilkins, Jason Coppell, John Laurie, Mamta Garg, Joanne Ewing, Stephen Knapper, Josephine Crowe, Frederick Chen, Ioannis Koutsavlis, Anna Godfrey, Siamak Arami, Mark Drummond, Jennifer L Byrne, Fiona Clark, Carolyn Mead-Harvey, Elizabeth Joanna Baxter, Mary Frances Frances McMullin, Adam J Mead
Ruxolitinib Versus Best Available Therapy for Polycythemia Vera Intolerant or Resistant to Hydroxycarbamide in a Randomized Trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
Adam J de Smith, Joseph L Wiemels, Adam J Mead, Irene Roberts, Anindita Roy, Logan G Spector
Backtracking to the future: unraveling the origins of childhood leukemia. Leukemia 38 (2) (2023)
Adam J de Smith, Joseph L Wiemels, Adam J Mead, Irene Roberts, Anindita Roy, Logan G Spector
Backtracking to the future: unraveling the origins of childhood leukemia. Leukemia (2023)
Adam J de Smith, Joseph L Wiemels, Adam J Mead, Irene Roberts, Anindita Roy, Logan G Spector
Backtracking to the future: unraveling the origins of childhood leukemia. Leukemia 38 (2) (2023)
Annatina Sarah Schnegg-Kaufmann, Julie A I Thoms, Golam Sarower Bhuyan, Henry R Hampton, Lachlin Vaughan, Kayleigh Rutherford, Purvi M Kakadia, Hui Mei Lee, Emma M V Johansson, Timothy W Failes, Greg M Arndt, Jason Koval, Robert Lindeman, Pauline Warburton, Alba Rodriguez-Meira, Adam J Mead, Ashwin Unnikrishnan, Sarah Davidson, Mark N Polizzotto, Mark Hertzberg, Elli Papaemmanuil, Stefan K Bohlander, Omid R Faridani, Christopher J Jolly, Fabio Zanini, John E Pimanda
Contribution of mutant HSC clones to immature and mature cells in MDS and CMML, and variations with AZA therapy. Blood 141 (11) (2023)
Alexandros Rampotas, Luke Carter-Brzezinski, Tim C Somervaille, James Forryan, Fotios P Panitsas, Claire N Harrison, Ruth Witherall, Andrew J Innes, Louise Wallis, Nauman M Butt, Bethan Psaila, Adam J Mead, Matthew Carter, Anna L Godfrey, Heather Laing, Mamta Garg, Sebastian Francis, Joanne Ewing, Chun Huat Teh, Hannah B Cowan, Peter Dyer, Conal McConville, Frances Wadelin, Sahra Ali, Andrew McGregor, Elizabeth Kulakov, Donal P McLornan, Jonathan Lambert
Outcomes and Characteristics of Non-Melanoma Skin Cancers in Patients with Myeloproliferative Neoplasms on Ruxolitinib. Blood (2023)
Adam J de Smith, Joseph L Wiemels, Adam J Mead, Irene Roberts, Anindita Roy, Logan G Spector
Backtracking to the future: unraveling the origins of childhood leukemia. Leukemia 38 (2) (2023)
Tiago C Luis, Nikolaos Barkas, Joana Carrelha, Alice Giustacchini, Stefania Mazzi, Ruggiero Norfo, Bishan Wu, Affaf Aliouat, Jose Antonio Guerrero, Alba Rodriguez-Meira, Tiphaine Bouriez-Jones, Iain C Macaulay, Maria Jasztal, Guangheng Zhu, Heyu Ni, Matthew J Robson, Randy D Blakely, Adam J Mead, Claus Nerlov, Cedric Ghevaert, Sten Eirik W Jacobsen
Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner. Nature communications 14 (1) (2023)
Donal P McLornan, Bethan Psaila, Joanne Ewing, Andrew J Innes, Siamak Arami, Jessica Brady, Nauman M Butt, Catherine Cargo, Nicholas C P Cross, Sebastian Francis, Rebecca Frewin, Mamta Garg, Anna L Godfrey, Anna Green, Alesia Khan, Steve Knapper, Jonathan Lambert, Andrew McGregor, Mary Frances Frances McMullin, Jyoti Nangalia, Pratap Neelakantan, Claire Woodley, Adam J Mead, Tim C P Somervaille, Claire N Harrison, null null
The management of myelofibrosis: A British Society for Haematology Guideline. British journal of haematology (2023)
John O Mascarenhas, Marina Kremyanskaya, Andrea Patriarca, Francesca Palandri, Timothy Devos, Francesco Passamonti, Raajit K Rampal, Adam J Mead, Gabriella Hobbs, Joseph M Scandura, Moshe Talpaz, Nikki Granacher, Tim C P Somervaille, Ronald Hoffman, Marielle J Wondergem, Mohamed E Salama, Gozde Colak, Jike Cui, Jean-Jacques Kiladjian, Alessandro Maria Maria Vannucchi, Srdan Verstovsek, Natalia Curto-García, Claire N Harrison, Vikas K Gupta
MANIFEST: Pelabresib in Combination With Ruxolitinib for Janus Kinase Inhibitor Treatment-Naïve Myelofibrosis. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
Adam J de Smith, Joseph L Wiemels, Adam J Mead, Irene Roberts, Anindita Roy, Logan G Spector
Backtracking to the future: unraveling the origins of childhood leukemia. Leukemia 38 (2) (2023)
Adam J de Smith, Joseph L Wiemels, Adam J Mead, Irene Roberts, Anindita Roy, Logan G Spector
Backtracking to the future: unraveling the origins of childhood leukemia. Leukemia 38 (2) (2023)
Adam J de Smith, Joseph L Wiemels, Adam J Mead, Irene Roberts, Anindita Roy, Logan G Spector
Backtracking to the future: unraveling the origins of childhood leukemia. Leukemia 38 (2) (2023)
Adam J de Smith, Joseph L Wiemels, Adam J Mead, Irene Roberts, Anindita Roy, Logan G Spector
Backtracking to the future: unraveling the origins of childhood leukemia. Leukemia 38 (2) (2023)
Adam J de Smith, Joseph L Wiemels, Adam J Mead, Irene Roberts, Anindita Roy, Logan G Spector
Backtracking to the future: unraveling the origins of childhood leukemia. Leukemia (2023)
Annatina Sarah Schnegg-Kaufmann, Julie A I Thoms, Golam Sarower Bhuyan, Henry R Hampton, Lachlin Vaughan, Kayleigh Rutherford, Purvi M Kakadia, Hui Mei Lee, Emma M V Johansson, Timothy W Failes, Greg M Arndt, Jason Koval, Robert Lindeman, Pauline Warburton, Alba Rodriguez-Meira, Adam J Mead, Ashwin Unnikrishnan, Sarah Davidson, Mark N Polizzotto, Mark Hertzberg, Elli Papaemmanuil, Stefan K Bohlander, Omid R Faridani, Christopher J Jolly, Fabio Zanini, John E Pimanda
Contribution of mutant HSC clones to immature and mature cells in MDS and CMML, and variations with AZA therapy. Blood 141 (11) (2023)
Pedro Luis Moura, Teresa Mortera Blanco, Isabel Juliana Hofman, Gabriele Todisco, Warren W Kretzschmar, Ann-Charlotte Björklund, Maria Creignou, Michael Hagemann-Jensen, Christoph Ziegenhain, David Cabrerizo Granados, Indira Barbosa, Gunilla Walldin, Monika Jansson, Neil Ashley, Adam J Mead, Vanessa Lundin, Marios Dimitriou, Tetsuichi Yoshizato, Petter S Woll, Seishi Ogawa, Rickard Sandberg, Sten Eirik W Jacobsen, Eva Hellström Lindberg
Erythroid differentiation enhances RNA mis-splicing in SF3B1-mutant myelodysplastic syndromes with ring sideroblasts. Cancer research (2023)
Adam J de Smith, Joseph L Wiemels, Adam J Mead, Irene Roberts, Anindita Roy, Logan G Spector
Backtracking to the future: unraveling the origins of childhood leukemia. Leukemia 38 (2) (2023)
Donal P McLornan, Anna L Godfrey, Anna Green, Rebecca Frewin, Siamak Arami, Jessica Brady, Nauman M Butt, Catherine Cargo, Joanne Ewing, Sebastian Francis, Mamta Garg, Claire N Harrison, Andrew J Innes, Alesia Khan, Steve Knapper, Jonathan Lambert, Adam J Mead, Andrew McGregor, Pratap Neelakantan, Bethan Psaila, Tim C P Somervaille, Claire Woodley, Jyoti Nangalia, Nicholas C P Cross, Mary Frances Frances McMullin, null null
Diagnosis and evaluation of prognosis of myelofibrosis: A British Society for Haematology Guideline. British journal of haematology (2023)
Hosuk Ryou, Korsuk Sirinukunwattana, Alan Aberdeen, Gillian Grindstaff, Bernadette J Stolz, Helen Byrne, Heather A Harrington, Nikolaos Sousos, Anna L Godfrey, Claire N Harrison, Bethan Psaila, Adam J Mead, Gabrielle Rees, Gareth D H Turner, Jens Rittscher, Daniel Royston
Correction: Continuous Indexing of Fibrosis (CIF): improving the assessment and classification of MPN patients. Leukemia (2023)
J M O'Sullivan, J Taylor, Aaron T Gerds, S Buckley, C N Harrison, Stephen T Oh, A F List, Kieran Howard, H Dreau, A Hamblin, Adam J Mead
RAS-pathway mutations are common in patients with ruxolitinib refractory/intolerant myelofibrosis: molecular analysis of the PAC203 cohort. Leukemia (2023)
Adam J de Smith, Joseph L Wiemels, Adam J Mead, Irene Roberts, Anindita Roy, Logan G Spector
Backtracking to the future: unraveling the origins of childhood leukemia. Leukemia 38 (2) (2023)
Zijian Fang, Giuditta Corbizi Fattori, Thomas McKerrell, Rebecca H Boucher, Aimee Jackson, Rachel S Fletcher, Dorian Forte, Jose-Ezequiel Martin, Sonia Fox, James Roberts, Rachel Glover, Erica Harris, Hannah R Bridges, Luigi Grassi, Alba Rodriguez-Meira, Adam J Mead, Stephen Knapper, Joanne Ewing, Nauman M Butt, Manish Jain, Sebastian Francis, Fiona J Clark, Jason Coppell, Mary Frances Frances McMullin, Frances Wadelin, Srinivasan Narayanan, Dragana Milojkovic, Mark W Drummond, Mallika Sekhar, Hesham ElDaly, Judy Hirst, Maike Paramor, Elizabeth Joanna Baxter, Anna L Godfrey, Claire N Harrison, Simon Mendez-Ferrer
Tamoxifen for the treatment of myeloproliferative neoplasms: A Phase II clinical trial and exploratory analysis. Nature communications 14 (1) (2023)
Alba Rodriguez-Meira, Ruggiero Norfo, Sean Wen, Agathe L Chédeville, Haseeb Rahman, Jennifer O'Sullivan, Guanlin Wang, Eleni Louka, Warren W Kretzschmar, Aimee Paterson, Charlotte Brierley, Jean-Edouard Martin, Caroline Demeule, Matthew Bashton, Nikolaos Sousos, Daniela Moralli, Lamia Subha Meem, Joana Carrelha, Bishan Wu, Angela Hamblin, Hélène Guermouche, Florence Pasquier, Christophe Marzac, Francois Girodon, William Vainchenker, Mark Drummond, Claire Harrison, J Ross Chapman, Isabelle Plo, Sten Eirik W Jacobsen, Bethan Psaila, Supat Thongjuea, Iléana Antony-Debré, Adam J Mead
Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution. Nature genetics (2023)
Hosuk Ryou, Korsuk Sirinukunwattana, Alan Aberdeen, Gillian Grindstaff, Bernadette J Stolz, Helen Byrne, Heather A Harrington, Nikolaos Sousos, Anna L Godfrey, Claire N Harrison, Bethan Psaila, Adam J Mead, Gabrielle Rees, Gareth D H Turner, Jens Rittscher, Daniel Royston
Correction: Continuous Indexing of Fibrosis (CIF): improving the assessment and classification of MPN patients. Leukemia (2023)
Nikolaos Sousos, Máire Ní Leathlobhair, Christina Simoglou Karali, Eleni Louka, Nicola Bienz, Daniel Royston, Sally-Ann Clark, Angela Hamblin, Kieran Howard, Vikram Mathews, Biju George, Anindita Roy, Bethan Psaila, David C Wedge, Adam J Mead
In utero origin of myelofibrosis presenting in adult monozygotic twins. Nature medicine 28 (6) (2022)
Namrata Rastogi, Juan Bautista Menendez Gonzalez, Vikas Kumar Srivastava, Bader Alanazi, Rehab N Alanazi, Owen M Hughes, Niamh S O'Neill, Amanda F Gilkes, Neil Ashley, Sumukh Deshpande, Robert M Andrews, Adam J Mead, Neil P Rodrigues, Stephen Knapper, Richard L Darley, Alex Tonks
Nuclear factor I-C overexpression promotes monocytic development and cell survival in acute myeloid leukemia. Leukemia 37 (2) (2022)
Annatina Sarah Schnegg-Kaufmann, Julie A I Thoms, Golam Sarower Bhuyan, Henry R Hampton, Lachlin Vaughan, Kayleigh Diane Rutherford, Purvi M Kakadia, Hui Mei Lee, Emma Mv Johansson, Timothy W Failes, Greg M Arndt, Jason Koval, Robert Lindeman, Pauline Warburton, Alba Rodriguez-Meira, Adam J Mead, Ashwin Unnikrishnan, Sarah Davidson, Mark Polizzotto, Mark Hertzberg, Elli Papaemmanuil, Stefan K Bohlander, Omid R Faridani, Christopher J Jolly, Fabio Zanini, John E Pimanda
Contribution of mutant HSC clones to immature and mature cells in MDS and CMML, and variations with AZA therapy. Blood (2022)
Namrata Rastogi, Juan Bautista Menendez Gonzalez, Vikas Kumar Srivastava, Bader Alanazi, Rehab N Alanazi, Owen M Hughes, Niamh S O'Neill, Amanda F Gilkes, Neil Ashley, Sumukh Deshpande, Robert M Andrews, Adam J Mead, Neil P Rodrigues, Stephen Knapper, Richard L Darley, Alex Tonks
Nuclear factor I-C overexpression promotes monocytic development and cell survival in acute myeloid leukemia. Leukemia 37 (2) (2022)
Namrata Rastogi, Juan Bautista Menendez Gonzalez, Vikas Kumar Srivastava, Bader Alanazi, Rehab N Alanazi, Owen M Hughes, Niamh S O'Neill, Amanda F Gilkes, Neil Ashley, Sumukh Deshpande, Robert M Andrews, Adam J Mead, Neil P Rodrigues, Stephen Knapper, Richard L Darley, Alex Tonks
Nuclear factor I-C overexpression promotes monocytic development and cell survival in acute myeloid leukemia. Leukemia 37 (2) (2022)
Clara Bueno, Susana Barrera, Alex Bataller, Valentín Ortiz-Maldonado, Natalina Elliot, Sorcha O'Byrne, Guanlin Wang, Montse Rovira, Francisco Gutierrez-Agüera, Juan L Trincado, María González-González, Mireia Morgades, Marc Sorigue, Paloma Bárcena, Samanta Romina Zanetti, Montserrat Torrebadell, Nerea Vega-García, Susana Rives, Mar Mallo, Francisco Solé, Adam J Mead, Irene Roberts, Supat Thongjuea, Bethan Psaila, Manel Juan, Julio Delgado, Alvaro Urbano-Ispizúa, Josep-María Ribera, Alberto Orfao, Anindita Roy, Pablo Menendez
CD34+CD19-CD22+ B-cell progenitors may underlie phenotypic escape in patients treated with CD19-directed therapies. Blood 140 (1) (2022)
Annatina Sarah Schnegg-Kaufmann, Julie A I Thoms, Golam Sarower Bhuyan, Henry R Hampton, Lachlin Vaughan, Kayleigh Diane Rutherford, Purvi M Kakadia, Hui Mei Lee, Emma Mv Johansson, Timothy W Failes, Greg M Arndt, Jason Koval, Robert Lindeman, Pauline Warburton, Alba Rodriguez-Meira, Adam J Mead, Ashwin Unnikrishnan, Sarah Davidson, Mark Polizzotto, Mark Hertzberg, Elli Papaemmanuil, Stefan K Bohlander, Omid R Faridani, Christopher J Jolly, Fabio Zanini, John E Pimanda
Contribution of mutant HSC clones to immature and mature cells in MDS and CMML, and variations with AZA therapy. Blood (2022)
Hosuk Ryou, Korsuk Sirinukunwattana, Alan Aberdeen, Gillian Grindstaff, Bernadette J Stolz, Helen Byrne, Heather A Harrington, Nikolaos Sousos, Anna L Godfrey, Claire N Harrison, Bethan Psaila, Adam J Mead, Gabrielle Rees, Gareth D H Turner, Jens Rittscher, Daniel Royston
Continuous Indexing of Fibrosis (CIF): improving the assessment and classification of MPN patients. Leukemia (2022)
Namrata Rastogi, Juan Bautista Menendez Gonzalez, Vikas Kumar Srivastava, Bader Alanazi, Rehab N Alanazi, Owen M Hughes, Niamh S O'Neill, Amanda F Gilkes, Neil Ashley, Sumukh Deshpande, Robert M Andrews, Adam J Mead, Neil P Rodrigues, Stephen Knapper, Richard L Darley, Alex Tonks
Nuclear factor I-C overexpression promotes monocytic development and cell survival in acute myeloid leukemia. Leukemia 37 (2) (2022)
Adam J Mead, Nauman M Butt, Waseem Nagi, Alastair Whiteway, Suriya Kirkpatrick, Ciro Rinaldi, Catherine Roughley, Sam Ackroyd, Joanne Ewing, Pratap Neelakantan, Mamta Garg, David Tucker, John Murphy, Hitesh Patel, Rozinder Bains, Gavin Chiu, Joe Hickey, Claire Harrison, Tim C P Somervaille
A retrospective real-world study of the current treatment pathways for myelofibrosis in the United Kingdom: the REALISM UK study. Therapeutic advances in hematology 13 (2022)
Namrata Rastogi, Juan Bautista Menendez Gonzalez, Vikas Kumar Srivastava, Bader Alanazi, Rehab N Alanazi, Owen M Hughes, Niamh S O'Neill, Amanda F Gilkes, Neil Ashley, Sumukh Deshpande, Robert M Andrews, Adam J Mead, Neil P Rodrigues, Stephen Knapper, Richard L Darley, Alex Tonks
Nuclear factor I-C overexpression promotes monocytic development and cell survival in acute myeloid leukemia. Leukemia 37 (2) (2022)
Namrata Rastogi, Juan Bautista Menendez Gonzalez, Vikas Kumar Srivastava, Bader Alanazi, Rehab N Alanazi, Owen M Hughes, Niamh S O'Neill, Amanda F Gilkes, Neil Ashley, Sumukh Deshpande, Robert M Andrews, Adam J Mead, Neil P Rodrigues, Stephen Knapper, Richard L Darley, Alex Tonks
Nuclear factor I-C overexpression promotes monocytic development and cell survival in acute myeloid leukemia. Leukemia (2022)
Gonzalo Carreno-Tarragona, Alberto Alvarez-Larran, Claire N Harrison, Jose Carlos Martínez Ávila, Juan Carlos Carlos Hernández-Boluda, Francisca Ferrer-Marín, Deepti H Radia, Elvira Mora Casterá, Sebastian Francis, Teresa González-Martínez, Kathryn Goddard, Manuel Mateo Pérez Encinas, Srinivasan Narayanan, Jose Maria Raya, Vikram Singh, Peter Toth, Xabier Gutiérrez, Paula Amat Martinez, Louisa McIlwaine, Magda Alobaidi, Karan Mayani, Andrew McGregor, Ruth Stuckey, Bethan Psaila, Adrian Segura, Caroline L Alvares, Kerri Davidson, Santiago Osorio, Robert Cutting, Caroline P Sweeney, Laura Rufian, Laura Moreno, Isabel Cuenca, Jeffrey Smith, Maria Luz Morales, Rodrigo Gil-Manso, Ioannis Koutsavlis, Lihui Wang, Adam J Mead, Maria Rozman, Joaquin Martínez-López, Rosa María Ayala, Nicholas C P Cross
CNL and aCML should be considered as single entity based on molecular profiles and outcomes. Blood advances (2022)
John O Mascarenhas, Heidi E Kosiorek, Josef T Prchal, Alessandro Rambaldi, Dmitriy Berenzon, Abdulraheem Yacoub, Claire N Harrison, Mary Frances Frances McMullin, Alessandro Maria Maria Vannucchi, Joanne Ewing, Casey L O'Connell, Jean-Jacques Kiladjian, Adam J Mead, Elliott F Winton, David S Leibowitz, Valerio De Stefano, Murat O Arcasoy, Craig M Kessler, Rosalind Catchatourian, Damiano Rondelli, Richard T Silver, Andrea Bacigalupo, Arnon Nagler, Marina Kremyanskaya, Max Fine Levine, Juan Esteban Arango Ossa, Erin M McGovern, Lonette Sandy, Mohamad E Salama, Vesna Najfeld, Joseph Tripodi, Noushin Farnoud, Alexander V Penson, Rona Singer Weinberg, Leah Price, Judith D Goldberg, Tiziano Barbui, Roberto Marchioli, Gianni Tognoni, Raajit K Rampal, Ruben A Mesa, Amylou C Dueck, Ronald Hoffman
A randomized phase 3 trial of interferon-α vs hydroxyurea in polycythemia vera and essential thrombocythemia. Blood 139 (19) (2022)
Claire N Harrison, Vikas K Gupta, Aaron T Gerds, Raajit K Rampal, Srdan Verstovsek, Moshe Talpaz, Jean-Jacques Kiladjian, Ruben A Mesa, Andrew T Kuykendall, Alessandro Maria Maria Vannucchi, Francesca Palandri, Sebastian Grosicki, Timothy Devos, Eric Jourdan, Marielle J Wondergem, Haifa Kathrin Al-Ali, Veronika Buxhofer-Ausch, Alberto Álvarez-Larrán, Andrea Patriarca, Marina Kremyanskaya, Adam J Mead, Sanjay Akhani, Yuri Sheikine, Gozde Colak, John O Mascarenhas
Phase III MANIFEST-2: pelabresib + ruxolitinib vs placebo + ruxolitinib in JAK inhibitor treatment-naive myelofibrosis. Future oncology (London, England) 18 (27) (2022)
Jennifer M O'Sullivan, Adam J Mead, Bethan Psaila
Single-cell methods in myeloproliferative neoplasms - old questions, new technologies. Blood (2022)
Namrata Rastogi, Juan Bautista Menendez Gonzalez, Vikas Kumar Srivastava, Bader Alanazi, Rehab N Alanazi, Owen M Hughes, Niamh S O'Neill, Amanda F Gilkes, Neil Ashley, Sumukh Deshpande, Robert M Andrews, Adam J Mead, Neil P Rodrigues, Stephen Knapper, Richard L Darley, Alex Tonks
Nuclear factor I-C overexpression promotes monocytic development and cell survival in acute myeloid leukemia. Leukemia (2022)
Namrata Rastogi, Juan Bautista Menendez Gonzalez, Vikas Kumar Srivastava, Bader Alanazi, Rehab N Alanazi, Owen M Hughes, Niamh S O'Neill, Amanda F Gilkes, Neil Ashley, Sumukh Deshpande, Robert M Andrews, Adam J Mead, Neil P Rodrigues, Stephen Knapper, Richard L Darley, Alex Tonks
Nuclear factor I-C overexpression promotes monocytic development and cell survival in acute myeloid leukemia. Leukemia 37 (2) (2022)
Wen Hao Neo, Yiran Meng, Alba Rodriguez-Meira, Muhammad Z H Fadlullah, Christopher A G Booth, Emanuele Azzoni, Supat Thongjuea, Marella F T R de Bruijn, Sten Eirik W Jacobsen, Adam J Mead, Georges Lacaud
Ezh2 is essential for the generation of functional yolk sac derived erythro-myeloid progenitors. Nature communications 12 (1) (2021)
Richard A Salisbury, Natalia Curto-Garcia, Jennifer O'Sullivan, Frederick Chen, Paolo Polzella, Anna L Godfrey, James Russell, Steven Knapper, John Willan, Rebecca Frewin, Shivani Joshi, Siamak Arami, Sarah Burns, Chun Huat Teh, Frances Wadelin, Jaymathi Dhanapal, Pratap Neelakantan, Dragana Milojkovic, Beth Psaila, Richard Szydlo, Sebastian Francis, Catherine Cargo, Manish Jain, Andrew McGregor, Louise Wallis, Andrew Duncombe, Hayder Hussein, Peter Dyer, Laura Munro, Lee Bond, Mary Frances Frances McMullin, Tim C P Somervaille, Mamta Garg, Mallika Sekhar, Claire Harrison, Adam J Mead, Andrew J Innes
Results of a national UK physician reported survey of COVID-19 infection in patients with a myeloproliferative neoplasm. Leukemia 35 (8) (2021)
Siobhan Rice, Thomas Jackson, Nicholas T Crump, Nicholas Fordham, Natalina Elliott, Sorcha O'Byrne, Maria Del Mar Lara Fanego, Dilys Addy, Trisevgeni Crabb, Carryl Dryden, Sarah Inglott, Dariusz Ladon, Gary Wright, Jack Bartram, Philip Ancliff, Adam J Mead, Christina Halsey, Irene Roberts, Thomas A Milne, Anindita Roy
A human fetal liver-derived infant MLL-AF4 acute lymphoblastic leukemia model reveals a distinct fetal gene expression program. Nature communications 12 (1) (2021)
Srdan Verstovsek, Chih-Cheng Chen, Miklós Egyed, Martin Ellis, Maria Laura Fox, Yeow T Goh, Vikas K Gupta, Claire Harrison, Jean-Jacques Kiladjian, Mihaela C Lazaroiu, Adam J Mead, Donal McLornan, Mary Frances Frances McMullin, Stephen T Oh, Andrew Charles Perkins, Uwe Platzbecker, Christof Scheid, Alessandro Maria Maria Vannucchi, Sung-Soo Yoon, Mark M Kowalski, Ruben A Mesa
MOMENTUM: momelotinib vs danazol in patients with myelofibrosis previously treated with JAKi who are symptomatic and anemic. Future oncology (London, England) 17 (12) (2021)
Nicholas C P Cross, Anna L Godfrey, Catherine Cargo, Mamta Garg, Adam J Mead, null null
The use of genetic tests to diagnose and manage patients with myeloproliferative and myeloproliferative/myelodysplastic neoplasms, and related disorders. British journal of haematology 195 (3) (2021)
Onima Chowdhury, Hannah Bruguier, Garry Mallett, Nikolaos Sousos, Kirsty Crozier, Caroline Allman, David Eyre, Sheila Lumley, Marie Strickland, Christina S Karali, Lauren Murphy, Alex Sternberg, Katie Jeffery, Adam J Mead, Andy Peniket, Bethan Psaila
Impaired antibody response to COVID-19 vaccination in patients with chronic myeloid neoplasms. British journal of haematology 194 (6) (2021)
Lauren C Murphy, Adam J Mead
Familial thrombocytopenia: The long and short of it. The Journal of experimental medicine 218 (6) (2021)
Wei Xiong Wen, Adam J Mead, Supat Thongjuea
VALERIE: Visual-based inspection of alternative splicing events at single-cell resolution. PLoS computational biology 16 (9) (2020)
Dragana Milojkovic, Nicholas C P Cross, Sahra Ali, Jenny Byrne, Gavin Campbell, Fiona L Dignan, Mark Drummond, Brian Huntly, Scott Marshall, Mary Frances Frances McMullin, Pratap Neelakantan, Manoj Raghavan, Muttuswamy Sivakumaran, Jane Tighe, Farooq A Wandroo, Fenella Willis, Fiona Glen, Louise Fildes, Sarah J Collington, Jacqueline Ryan, Richard E Clark, Adam J Mead
Real-world tyrosine kinase inhibitor treatment pathways, monitoring patterns and responses in patients with chronic myeloid leukaemia in the United Kingdom: the UK TARGET CML study. British journal of haematology 192 (1) (2020)
Lucia M Moreira, Abhijit Takawale, Mohit M Hulsurkar, David A Menassa, Agne Antanaviciute, Satadru K Lahiri, Neelam Mehta, Neil Evans, Constantinos Psarros, Paul Robinson, Alexander J Sparrow, Marc-Antoine Gillis, Neil Ashley, Patrice Naud, Javier Barallobre-Barreiro, Konstantinos Theofilatos, Angela Lee, Mary Norris, Michele V Clarke, Patricia K Russell, Barabara Casadei, Shoumo Bhattacharya, Jeffrey D Zajac, Rachel A Davey, Martin Sirois, Adam J Mead, Alison Simmons, Manuel Mayr, Rana Sayeed, George Krasopoulos, Charles Redwood, Keith M Channon, Jean-Claude Tardif, Xander H T Wehrens, Stanley Nattel, Svetlana Reilly
Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia. Nature 587 (7834) (2020)
Onima Chowdhury, Jennifer O'Sullivan, Nikolaos Barkas, Guanlin Wang, Gemma Buck, Angela Hamblin, Ayalew Tefferi, Haifa K Al-Ali, Giovanni Barosi, Timothy Devos, Heinz Gisslinger, Qian Jiang, Jean-Jacques Kiladjian, Ruben Mesa, Francesco Passamonti, Vincent Ribrag, Gary Schiller, Alessandro M Vannucchi, Daobin Zhou, Mary Frances Frances McMullin, Jianhua Zhong, Robert Peter Gale, Adam J Mead, null null
Spliceosome mutations are common in persons with myeloproliferative neoplasm-associated myelofibrosis with RBC-transfusion-dependence and correlate with response to pomalidomide. Leukemia 35 (4) (2020)
Graeme Smith, Jane Apperley, Dragana Milojkovic, Nicholas C P Cross, Letizia Foroni, Jenny Byrne, Andy Goringe, Anupama Rao, Jamshid Khorashad, Hugues de Lavallade, Adam J Mead, Wendy Osborne, Chris Plummer, Gail Jones, Mhairi Copland, null null
A British Society for Haematology Guideline on the diagnosis and management of chronic myeloid leukaemia. British journal of haematology 191 (2) (2020)
Sarah Gooding, Sam W Z Olechnowicz, Emma V Morris, Andrew E Armitage, Joao Arezes, Joe Frost, Emmanouela Repapi, James R Edwards, Neil Ashley, Craig Waugh, Nicola Gray, Erik Martinez-Hackert, Pei Jin Lim, Sant-Rayn Pasricha, Helen J Knowles, Adam J Mead, Karthik Ramasamy, Alexander Drakesmith, Claire M Edwards
Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease. Nature communications 10 (1) (2019)
Wen Hao Neo, Christopher A G Booth, Emanuele Azzoni, Lijun Chi, Paul Delgado-Olguín, Marella F T R de Bruijn, Sten Eirik W Jacobsen, Adam J Mead
Cell-extrinsic hematopoietic impact of Ezh2 inactivation in fetal liver endothelial cells. Blood 131 (20) (2018)
Adam J Mead, Wen Hao Neo, Nikolaos Barkas, Sahoko Matsuoka, Alice Giustacchini, Raffaella Facchini, Supat Thongjuea, Lauren Jamieson, Christopher A G Booth, Nicholas J Fordham, Cristina Di Genua, Deborah Atkinson, Onima Chowdhury, Emmanouela Repapi, Nicki Gray, Shabnam Kharazi, Sally-Ann Clark, Tiphaine Bouriez, Petter S Woll, Toshio Suda, Claus Nerlov, Sten Eirik W Jacobsen
Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation. The Journal of experimental medicine 214 (7) (2017)
Alice Giustacchini, Supat Thongjuea, Nikolaos Barkas, Petter S Woll, Benjamin J Povinelli, Christopher A G Booth, Paul Sopp, Ruggiero Norfo, Alba Rodriguez-Meira, Neil Ashley, Lauren Jamieson, Paresh Vyas, Kristina Anderson, Åsa Segerstolpe, Hong Qian, Ulla Olsson-Strömberg, Satu Mustjoki, Rickard Sandberg, Sten Eirik W Jacobsen, Adam J Mead
Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia. Nature medicine 23 (6) (2017)
Stephen John Loughran, Federico Comoglio, Fiona K Hamey, Alice Giustacchini, Youssef Errami, Eleanor M Earp, Berthold Göttgens, Sten Eirik W Jacobsen, Adam J Mead, Brian Hendrich, Anthony R Green
Mbd3/NuRD controls lymphoid cell fate and inhibits tumorigenesis by repressing a B cell transcriptional program. The Journal of experimental medicine 214 (10) (2017)