Daniel A Bachovchin

ORCID

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 17

Top Venues

Journal of medicinal chemistry

Nature chemical biology

Cell death & disease

ACS chemical biology

This page only lists publications with an associated author ORCID identifier.

Publications

Michael B Geeson, Jeffrey C Hsiao, Lydia P Tsamouri, Daniel P Ball, Daniel A Bachovchin
The interaction between NLRP1 and oxidized TRX1 involves a transient disulfide bond. bioRxiv : the preprint server for biology (2023)
Qifeng Chen, Alvin Wang, Dominic J Covelli, Abir Bhattacharjee, Qinghui Wang, Elizabeth L Orth-He, Sahana D Rao, Hsin-Che Huang, Daniel P Ball, Jeffrey C Hsiao, Daniel A Bachovchin
Optimized M24B Aminopeptidase Inhibitors for CARD8 Inflammasome Activation. Journal of medicinal chemistry 66 (4) (2023)
Qifeng Chen, Alvin Wang, Dominic J Covelli, Abir Bhattacharjee, Qinghui Wang, Elizabeth L Orth-He, Sahana D Rao, Hsin-Che Huang, Daniel P Ball, Jeffrey C Hsiao, Daniel A Bachovchin
Optimized M24B Aminopeptidase Inhibitors for CARD8 Inflammasome Activation. Journal of medicinal chemistry 66 (4) (2023)
Qifeng Chen, Alvin Wang, Dominic J Covelli, Abir Bhattacharjee, Qinghui Wang, Elizabeth L Orth-He, Sahana D Rao, Hsin-Che Huang, Daniel P Ball, Jeffrey C Hsiao, Daniel A Bachovchin
Optimized M24B Aminopeptidase Inhibitors for CARD8 Inflammasome Activation. Journal of medicinal chemistry 66 (4) (2023)
Qifeng Chen, Alvin Wang, Dominic J Covelli, Abir Bhattacharjee, Qinghui Wang, Elizabeth L Orth-He, Sahana D Rao, Hsin-Che Huang, Daniel P Ball, Jeffrey C Hsiao, Daniel A Bachovchin
Optimized M24B Aminopeptidase Inhibitors for CARD8 Inflammasome Activation. Journal of medicinal chemistry (2023)
Matthew R Volpe, José A Velilla, Martin Daniel-Ivad, Jenny J Yao, Alessia Stornetta, Peter W Villalta, Hsin-Che Huang, Daniel A Bachovchin, Silvia Balbo, Rachelle Gaudet, Emily P Balskus
A small molecule inhibitor prevents gut bacterial genotoxin production. Nature chemical biology (2022)
Daniel P Ball, Lydia P Tsamouri, Alvin E Wang, Hsin-Che Huang, Charles D Warren, Qinghui Wang, Isabelle H Edmondson, Andrew R Griswold, Sahana D Rao, Darren C Johnson, Daniel A Bachovchin
Oxidized thioredoxin-1 restrains the NLRP1 inflammasome. Science immunology 7 (77) (2022)
Sahana D Rao, Qifeng Chen, Qinghui Wang, Elizabeth L Orth-He, Michelle Saoi, Andrew R Griswold, Abir Bhattacharjee, Daniel P Ball, Hsin-Che Huang, Ashley J Chui, Dominic J Covelli, Shaochen You, Justin R Cross, Daniel A Bachovchin
M24B aminopeptidase inhibitors selectively activate the CARD8 inflammasome. Nature chemical biology 18 (5) (2022)
L Robert Hollingsworth, Humayun Sharif, Andrew R Griswold, Pietro Fontana, Julian Mintseris, Kevin B Dagbay, Joao A Paulo, Steven P Gygi, Daniel A Bachovchin, Hao Wu
DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation. Nature 592 (7856) (2021)
L Robert Hollingsworth, Liron David, Yang Li, Andrew R Griswold, Jianbin Ruan, Humayun Sharif, Pietro Fontana, Elizabeth L Orth-He, Tian-Min Fu, Daniel A Bachovchin, Hao Wu
Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes. Nature communications 12 (1) (2021)
Daniel P Ball, Cornelius Y Taabazuing, Andrew R Griswold, Elizabeth L Orth, Sahana D Rao, Ilana B Kotliar, Lauren E Vostal, Darren C Johnson, Daniel A Bachovchin
Caspase-1 interdomain linker cleavage is required for pyroptosis. Life science alliance 3 (3) (2020)
Cornelius Y Taabazuing, Andrew R Griswold, Daniel A Bachovchin
The NLRP1 and CARD8 inflammasomes. Immunological reviews 297 (1) (2020)
Darren C Johnson, Marian C Okondo, Elizabeth L Orth, Sahana D Rao, Hsin-Che Huang, Daniel P Ball, Daniel A Bachovchin
DPP8/9 inhibitors activate the CARD8 inflammasome in resting lymphocytes. Cell death & disease 11 (8) (2020)
Andrew R Griswold, Daniel P Ball, Abir Bhattacharjee, Ashley J Chui, Sahana D Rao, Cornelius Y Taabazuing, Daniel A Bachovchin
DPP9's Enzymatic Activity and Not Its Binding to CARD8 Inhibits Inflammasome Activation. ACS chemical biology 14 (11) (2019)
Kuo Gai, Marian C Okondo, Sahana D Rao, Ashley J Chui, Daniel P Ball, Darren C Johnson, Daniel A Bachovchin
DPP8/9 inhibitors are universal activators of functional NLRP1 alleles. Cell death & disease 10 (8) (2019)
Ashley J Chui, Marian C Okondo, Sahana D Rao, Kuo Gai, Andrew R Griswold, Darren C Johnson, Daniel P Ball, Cornelius Y Taabazuing, Elizabeth L Orth, Brooke A Vittimberga, Daniel A Bachovchin
N-terminal degradation activates the NLRP1B inflammasome. Science (New York, N.Y.) 364 (6435) (2019)
Benjamin J Buckley, Ashraf Aboelela, Elahe Minaei, Longguang X Jiang, Zhihong Xu, Umar Ali, Karen Fildes, Chen-Yi Cheung, Simon M Cook, Darren C Johnson, Daniel A Bachovchin, Gregory M Cook, Minoti Apte, Ming-Dong Huang, Marie Ranson, Michael J Kelso
6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer. Journal of medicinal chemistry 61 (18) (2018)

Daniel A Bachovchin.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

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Daniel A Bachovchin