Jeffrey R Holt

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 18

Top Topics

Cerebrospinal Fluid

Top Venues

Science translational medicine

The Journal of general physiology

Science advances

EMBO molecular medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Jeffrey R Holt, Robert Fettiplace, Ulrich Mueller
Sensory transduction in auditory hair cells-PIEZOs can't touch this. The Journal of general physiology 156 (6) (2024)
Jeffrey R Holt, Robert Fettiplace, Ulrich Mueller
Sensory transduction in auditory hair cells-PIEZOs can't touch this. The Journal of general physiology 156 (6) (2024)
Jeffrey R Holt, Robert Fettiplace, Ulrich Mueller
Sensory transduction in auditory hair cells-PIEZOs can't touch this. The Journal of general physiology 156 (6) (2024)
Jeffrey R Holt, Robert Fettiplace, Ulrich Mueller
Sensory transduction in auditory hair cells-PIEZOs can't touch this. The Journal of general physiology 156 (6) (2024)
Barbara K Mathiesen, Leo M Miyakoshi, Christopher R Cederroth, Evangelia Tserga, Corstiaen Versteegh, Peter A R Bork, Natalie Linea Hauglund, Ryszard Stefan Gomolka, Yuki Mori, Niklas K Edvall, Stephanie Rouse, Kjeld Møllgård, Jeffrey R Holt, Maiken Nedergaard, Barbara Canlon
Delivery of gene therapy through a cerebrospinal fluid conduit to rescue hearing in adult mice. Science translational medicine 15 (702) (2023)
Barbara K Mathiesen, Leo M Miyakoshi, Christopher R Cederroth, Evangelia Tserga, Corstiaen Versteegh, Peter A R Bork, Natalie Linea Hauglund, Ryszard Stefan Gomolka, Yuki Mori, Niklas K Edvall, Stephanie Rouse, Kjeld Møllgård, Jeffrey R Holt, Maiken Nedergaard, Barbara Canlon
Delivery of gene therapy through a cerebrospinal fluid conduit to rescue hearing in adult mice. Science translational medicine 15 (702) (2023)
Barbara K Mathiesen, Leo M Miyakoshi, Christopher R Cederroth, Evangelia Tserga, Corstiaen Versteegh, Peter A R Bork, Natalie Linea Hauglund, Ryszard Stefan Gomolka, Yuki Mori, Niklas K Edvall, Stephanie Rouse, Kjeld Møllgård, Jeffrey R Holt, Maiken Nedergaard, Barbara Canlon
Delivery of gene therapy through a cerebrospinal fluid conduit to rescue hearing in adult mice. Science translational medicine 15 (702) (2023)
Irina Marcovich, Nicholas K Baer, Olga Shubina-Oleinik, Rachel Eclov, Clayton W Beard, Jeffrey R Holt
Optimized AAV Vectors for TMC1 Gene Therapy in a Humanized Mouse Model of DFNB7/11. Biomolecules 12 (7) (2022)
Wang Zheng, Chen Shen, Longfei Wang, Shaun Rawson, Wen Jun Xie, Carl Nist-Lund, Jason Wu, Zhangfei Shen, Shiyu Xia, Jeffrey R Holt, Hao Wu, Tian-Min Fu
pH regulates potassium conductance and drives a constitutive proton current in human TMEM175. Science advances 8 (12) (2022)
Edward S A van Beelen, Wouter H van der Valk, Thijs O Verhagen, John C M J de Groot, Margot A Madison, Wijs Shadmanfar, Erik F Hensen, Jeroen C Jansen, Peter Paul G van Benthem, Jeffrey R Holt, Heiko Locher
Efficient Viral Transduction in Fetal and Adult Human Inner Ear Explants with AAV9-PHP.B Vectors. Biomolecules 12 (6) (2022)
Wei-Hsi Yeh, Olga Shubina-Oleinik, Jonathan M Levy, Bifeng Pan, Gregory A Newby, Michael Wornow, Rachel Burt, Jonathan C Chen, Jeffrey R Holt, David R Liu
In vivo base editing restores sensory transduction and transiently improves auditory function in a mouse model of recessive deafness. Science translational medicine 12 (546) (2021)
Olga Shubina-Oleinik, Carl Nist-Lund, Courtney E French, Shira Rockowitz, A Eliot Shearer, Jeffrey R Holt
Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss. Science advances 7 (51) (2021)
John Lee, Kosuke Kawai, Jeffrey R Holt, Gwenaëlle Sg Géléoc
Sensory transduction is required for normal development and maturation of cochlear inner hair cell synapses. eLife 10 (2021)
Jeffrey R Holt, Mélanie Tobin, Johannes Elferich, Eric Gouaux, Angela Ballesteros, Zhiqiang Yan, Zubair M Ahmed, Teresa Nicolson
Putting the Pieces Together: the Hair Cell Transduction Complex. Journal of the Association for Research in Otolaryngology : JARO 22 (6) (2021)
Shahar Taiber, Roie Cohen, Ofer Yizhar-Barnea, David Sprinzak, Jeffrey R Holt, Karen B Avraham
Neonatal AAV gene therapy rescues hearing in a mouse model of SYNE4 deafness. EMBO molecular medicine 13 (2) (2020)
Jeffrey R Holt, Gwénaëlle S G Géléoc
Split otoferlins reunited. EMBO molecular medicine 11 (1) (2019)
Benjamin W Thuronyi, Luke W Koblan, Jonathan M Levy, Wei-Hsi Yeh, Christine Zheng, Gregory A Newby, Christopher Wilson, Mantu Bhaumik, Olga Shubina-Oleinik, Jeffrey R Holt, David R Liu
Continuous evolution of base editors with expanded target compatibility and improved activity. Nature biotechnology 37 (9) (2019)
Bence György, Carl Nist-Lund, Bifeng Pan, Yukako Asai, K Domenica Karavitaki, Benjamin P Kleinstiver, Sara P Garcia, Mikołaj P Zaborowski, Paola Solanes, Sofia Spataro, Bernard L Schneider, J Keith Joung, Gwenaëlle S G Géléoc, Jeffrey R Holt, David P Corey
Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss. Nature medicine 25 (7) (2019)